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The map label for this gene is fnrL [H]

Identifier: 209550266

GI number: 209550266

Start: 2727172

End: 2727891

Strand: Reverse

Name: fnrL [H]

Synonym: Rleg2_2686

Alternate gene names: 209550266

Gene position: 2727891-2727172 (Counterclockwise)

Preceding gene: 209550268

Following gene: 209550265

Centisome position: 60.11

GC content: 61.25

Gene sequence:

>720_bases
GTGATTGAAGCCCTGCTGCTCAATCTTGGAAGCCGCGATGTGCTTTCGGCTGAAGAGGAGAACCTTCTTAGGTCGATCCT
GGTCAAGGACAGGCATTTCGTTGCAGGAGAGGATATCGTCCTCGAAGGCAGCCGCCCGCCCTACAGCACCCTGCTGCTCG
ATGGTTTTGCGGCGCGCTACAAGGTGATGGCCGATGGCAGCCGGCAGATCACCGCGCTGCATGTCGCCGGCGATTTCGTC
GATCTGCATGCCTTTCCCGTCAAGAAGATGGATCACGGCATCGTTGCGCTGTCGACCTGTCATGTCGCCTTCGCCGATCA
TGCCGATCTCAGGGCGATCACCGAGCGCATGCCGCATCTGACCCGGCTGCTCTGGCTCGATACGCTGGTCGATGGCGCCA
TTCACCGCGAGTGGATCGTCGCCATGGGCCGGCGCTCCAAACGCGCCCATATCGCCCACCTCGTCTGCGAGCTTTTCGTG
CGGCTGCAGGTCGTCAAACGGACGCGCGGCGCCAGCTTCCAGTTTCCGTTGACGCAGATCGAGATGGCCGATGTGCTCGG
CGTTTCCGTCGTCCATCTGAACAAGACGCTGCAGGCGCTGAGGCGCGAGGGCGTTTTCACTTGGGAGAACCGGACGATCA
CCATCGTCGACTGGGAGCGCCTGCAGGAAATCGCCGAATTCGACCCCGCCTATCTGAACATCTTCAAGGAGCCGCGCTGA

Upstream 100 bases:

>100_bases
ACAGATGAAGACAATTGTTCCCGAGGCTAGGCATTGATTCTTATAGAAAATACAGGTCGCATCGTCATGATCTCCTCTTG
CGCTATCGGTGGAAAAGCCC

Downstream 100 bases:

>100_bases
CGCCAGACACGCGGGGCCAGACATGCGAGGCCTGAGACGCGATGCCGGAAGGCGCGACATCATATCCGCTCGTTGCAATT
GACAAACCGCTCATCGGAGC

Product: Crp/Fnr family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MIEALLLNLGSRDVLSAEEENLLRSILVKDRHFVAGEDIVLEGSRPPYSTLLLDGFAARYKVMADGSRQITALHVAGDFV
DLHAFPVKKMDHGIVALSTCHVAFADHADLRAITERMPHLTRLLWLDTLVDGAIHREWIVAMGRRSKRAHIAHLVCELFV
RLQVVKRTRGASFQFPLTQIEMADVLGVSVVHLNKTLQALRREGVFTWENRTITIVDWERLQEIAEFDPAYLNIFKEPR

Sequences:

>Translated_239_residues
MIEALLLNLGSRDVLSAEEENLLRSILVKDRHFVAGEDIVLEGSRPPYSTLLLDGFAARYKVMADGSRQITALHVAGDFV
DLHAFPVKKMDHGIVALSTCHVAFADHADLRAITERMPHLTRLLWLDTLVDGAIHREWIVAMGRRSKRAHIAHLVCELFV
RLQVVKRTRGASFQFPLTQIEMADVLGVSVVHLNKTLQALRREGVFTWENRTITIVDWERLQEIAEFDPAYLNIFKEPR
>Mature_239_residues
MIEALLLNLGSRDVLSAEEENLLRSILVKDRHFVAGEDIVLEGSRPPYSTLLLDGFAARYKVMADGSRQITALHVAGDFV
DLHAFPVKKMDHGIVALSTCHVAFADHADLRAITERMPHLTRLLWLDTLVDGAIHREWIVAMGRRSKRAHIAHLVCELFV
RLQVVKRTRGASFQFPLTQIEMADVLGVSVVHLNKTLQALRREGVFTWENRTITIVDWERLQEIAEFDPAYLNIFKEPR

Specific function: Anaerobic regulatory protein; transcriptional activator of hemA. Appears to regulate other genes [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 27167; Mature: 27167

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEALLLNLGSRDVLSAEEENLLRSILVKDRHFVAGEDIVLEGSRPPYSTLLLDGFAARY
CCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCEECCCCEEEECCCCCHHHHHHHHHHHHE
KVMADGSRQITALHVAGDFVDLHAFPVKKMDHGIVALSTCHVAFADHADLRAITERMPHL
EEEECCCCEEEEEEEECCEEEECCCCCHHCCCCEEEEEEEEEEECCCHHHHHHHHHHHHH
TRLLWLDTLVDGAIHREWIVAMGRRSKRAHIAHLVCELFVRLQVVKRTRGASFQFPLTQI
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHH
EMADVLGVSVVHLNKTLQALRREGVFTWENRTITIVDWERLQEIAEFDPAYLNIFKEPR
HHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEEHHHHHHHHHCCCHHHHEECCCC
>Mature Secondary Structure
MIEALLLNLGSRDVLSAEEENLLRSILVKDRHFVAGEDIVLEGSRPPYSTLLLDGFAARY
CCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCEECCCCEEEECCCCCHHHHHHHHHHHHE
KVMADGSRQITALHVAGDFVDLHAFPVKKMDHGIVALSTCHVAFADHADLRAITERMPHL
EEEECCCCEEEEEEEECCEEEECCCCCHHCCCCEEEEEEEEEEECCCHHHHHHHHHHHHH
TRLLWLDTLVDGAIHREWIVAMGRRSKRAHIAHLVCELFVRLQVVKRTRGASFQFPLTQI
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHH
EMADVLGVSVVHLNKTLQALRREGVFTWENRTITIVDWERLQEIAEFDPAYLNIFKEPR
HHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEEHHHHHHHHHCCCHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592416 [H]