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The map label for this gene is yajO [H]

Identifier: 209550131

GI number: 209550131

Start: 2582715

End: 2583749

Strand: Reverse

Name: yajO [H]

Synonym: Rleg2_2549

Alternate gene names: 209550131

Gene position: 2583749-2582715 (Counterclockwise)

Preceding gene: 209550134

Following gene: 209550130

Centisome position: 56.94

GC content: 66.28

Gene sequence:

>1035_bases
ATGGACTACAGAAATCTCGGTGCATCCGGGCTCAGAGTGCCGGTGTTGAGCTTTGGCGCCGGCACATTTGGCGGCAGCGG
CCCGCTGTTTGGCGCCTGGGGTAATACCGAGGCGGACGAGGCGCGGCGGCTCGTCGACATCTGCCTCGAAGCCGGCGTCA
ATCTCTTCGACACCGCCGACGTCTATTCGGCCGGCGCTTCCGAGGAGGTGCTCGGCCAGGCGATCCGCGGCCGGCGCGAC
GCCGTGCTGATCTCGACGAAGACGGCGCTGCCGATCGGCGAGGGGCCGCAGGACTGGGGAACGTCGCGGGCGCGGCTGAT
CCGTGCCACCGAGGCTGCGCTCAGCCGGCTCGGAACCGACTATATCGACCTCCTGCAACTGCACGCCTTCGATGCCTCGA
CGCCGGTCGGCGAGGTGCTGTCGACGCTCGACGGGCTCGTGGCATCCGGCAAGATCCGCTATGTCGGTGTGTCCAACTTT
GCCGGCTGGGAACTGATGAAGTCGCTTGCGGTGGCCGAGCGCCATGGTTATCCGCGTTACGTCGCCCATCAGGTCTATTA
TTCGCTGGCGGGGCGCGATTACGAATGGGAGCTGATGCCGCTCGGCGCCGACCAGGGCGTCGGCGCCCTGGTCTGGAGCC
CGCTCGCCTGGGGACGGCTGACCGGCAAGATCCGCCGCGGCCAGCCGCTGCCCAGTGAGAGCCGGCTGCACGAGACGGCG
CAATATGGCCCGCCGGTCGACGACGAGAAGCTCTTCGATATCGTCGATGTCCTGGATGCCATCGCAGAGGAAACCGGCAA
GACGGTGCCGCAGATCGCCATCAACTGGCTGCTCGGGCGACCGACGGTATCGAGCGTCATCATCGGTGCCCGCAACGAGG
AGCAGCTCAGGCAGAACCTCGGCGCGGTCGGCTGGAGCCTGTCGAAGGAGCAAATCGAAAAGCTCGACGCCGTCAGCGCG
GTGACAACGCCCTATCCCTATTTCCCCTATCGGCGGCAAGAGGGTTTCGCGCGGCTCAATCCGCCAATCGTCTAG

Upstream 100 bases:

>100_bases
CGGCTCATGATGAATTCAAGTCACAGATGATTTGCTCGCAGGCAATCTATATCACCGCGCGGTCGAGGTCTATCTTAGTG
GAAACGAAGGAGACAGATCC

Downstream 100 bases:

>100_bases
GCGGCGGACCGGCGTATAACAAAAGGGGAATGAAATCTTCTCCCAATCTTAACTGGACAGTCGCTTTGACTTGCCGCATA
CCCAGCCTGACCCCATGGGG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MDYRNLGASGLRVPVLSFGAGTFGGSGPLFGAWGNTEADEARRLVDICLEAGVNLFDTADVYSAGASEEVLGQAIRGRRD
AVLISTKTALPIGEGPQDWGTSRARLIRATEAALSRLGTDYIDLLQLHAFDASTPVGEVLSTLDGLVASGKIRYVGVSNF
AGWELMKSLAVAERHGYPRYVAHQVYYSLAGRDYEWELMPLGADQGVGALVWSPLAWGRLTGKIRRGQPLPSESRLHETA
QYGPPVDDEKLFDIVDVLDAIAEETGKTVPQIAINWLLGRPTVSSVIIGARNEEQLRQNLGAVGWSLSKEQIEKLDAVSA
VTTPYPYFPYRRQEGFARLNPPIV

Sequences:

>Translated_344_residues
MDYRNLGASGLRVPVLSFGAGTFGGSGPLFGAWGNTEADEARRLVDICLEAGVNLFDTADVYSAGASEEVLGQAIRGRRD
AVLISTKTALPIGEGPQDWGTSRARLIRATEAALSRLGTDYIDLLQLHAFDASTPVGEVLSTLDGLVASGKIRYVGVSNF
AGWELMKSLAVAERHGYPRYVAHQVYYSLAGRDYEWELMPLGADQGVGALVWSPLAWGRLTGKIRRGQPLPSESRLHETA
QYGPPVDDEKLFDIVDVLDAIAEETGKTVPQIAINWLLGRPTVSSVIIGARNEEQLRQNLGAVGWSLSKEQIEKLDAVSA
VTTPYPYFPYRRQEGFARLNPPIV
>Mature_344_residues
MDYRNLGASGLRVPVLSFGAGTFGGSGPLFGAWGNTEADEARRLVDICLEAGVNLFDTADVYSAGASEEVLGQAIRGRRD
AVLISTKTALPIGEGPQDWGTSRARLIRATEAALSRLGTDYIDLLQLHAFDASTPVGEVLSTLDGLVASGKIRYVGVSNF
AGWELMKSLAVAERHGYPRYVAHQVYYSLAGRDYEWELMPLGADQGVGALVWSPLAWGRLTGKIRRGQPLPSESRLHETA
QYGPPVDDEKLFDIVDVLDAIAEETGKTVPQIAINWLLGRPTVSSVIIGARNEEQLRQNLGAVGWSLSKEQIEKLDAVSA
VTTPYPYFPYRRQEGFARLNPPIV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=341, Percent_Identity=34.8973607038123, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI27436962, Length=341, Percent_Identity=34.8973607038123, Blast_Score=168, Evalue=6e-42,
Organism=Homo sapiens, GI27436966, Length=341, Percent_Identity=34.6041055718475, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI27436969, Length=341, Percent_Identity=34.8973607038123, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI4504825, Length=339, Percent_Identity=34.8082595870207, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI27436971, Length=312, Percent_Identity=32.0512820512821, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI223718702, Length=271, Percent_Identity=32.4723247232472, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI41327764, Length=273, Percent_Identity=30.03663003663, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI41152114, Length=271, Percent_Identity=30.9963099630996, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI87081735, Length=334, Percent_Identity=38.3233532934132, Blast_Score=215, Evalue=3e-57,
Organism=Escherichia coli, GI1789375, Length=329, Percent_Identity=32.2188449848024, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1789199, Length=356, Percent_Identity=30.6179775280899, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1788070, Length=323, Percent_Identity=30.3405572755418, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788081, Length=291, Percent_Identity=27.8350515463918, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI48994888, Length=314, Percent_Identity=24.8407643312102, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI212645785, Length=319, Percent_Identity=24.1379310344828, Blast_Score=74, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6325169, Length=354, Percent_Identity=27.1186440677966, Blast_Score=148, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6323998, Length=329, Percent_Identity=29.1793313069909, Blast_Score=127, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6319958, Length=303, Percent_Identity=28.0528052805281, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6322615, Length=267, Percent_Identity=26.5917602996255, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6319951, Length=328, Percent_Identity=25.3048780487805, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24646155, Length=333, Percent_Identity=29.1291291291291, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24640980, Length=323, Percent_Identity=26.3157894736842, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45549126, Length=323, Percent_Identity=26.3157894736842, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24646159, Length=321, Percent_Identity=26.1682242990654, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37344; Mature: 37344

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00062 ALDOKETO_REDUCTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYRNLGASGLRVPVLSFGAGTFGGSGPLFGAWGNTEADEARRLVDICLEAGVNLFDTAD
CCCCCCCCCCCEEEHEEECCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCCEECHH
VYSAGASEEVLGQAIRGRRDAVLISTKTALPIGEGPQDWGTSRARLIRATEAALSRLGTD
HHHCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCH
YIDLLQLHAFDASTPVGEVLSTLDGLVASGKIRYVGVSNFAGWELMKSLAVAERHGYPRY
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHCCCHHH
VAHQVYYSLAGRDYEWELMPLGADQGVGALVWSPLAWGRLTGKIRRGQPLPSESRLHETA
HHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHH
QYGPPVDDEKLFDIVDVLDAIAEETGKTVPQIAINWLLGRPTVSSVIIGARNEEQLRQNL
HCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHEECCCCHHHHHHHH
GAVGWSLSKEQIEKLDAVSAVTTPYPYFPYRRQEGFARLNPPIV
HHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCC
>Mature Secondary Structure
MDYRNLGASGLRVPVLSFGAGTFGGSGPLFGAWGNTEADEARRLVDICLEAGVNLFDTAD
CCCCCCCCCCCEEEHEEECCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCCEECHH
VYSAGASEEVLGQAIRGRRDAVLISTKTALPIGEGPQDWGTSRARLIRATEAALSRLGTD
HHHCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCH
YIDLLQLHAFDASTPVGEVLSTLDGLVASGKIRYVGVSNFAGWELMKSLAVAERHGYPRY
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHCCCHHH
VAHQVYYSLAGRDYEWELMPLGADQGVGALVWSPLAWGRLTGKIRRGQPLPSESRLHETA
HHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHH
QYGPPVDDEKLFDIVDVLDAIAEETGKTVPQIAINWLLGRPTVSSVIIGARNEEQLRQNL
HCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHEECCCCHHHHHHHH
GAVGWSLSKEQIEKLDAVSAVTTPYPYFPYRRQEGFARLNPPIV
HHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]