Click here to switch to the map view.

The map label for this gene is degP [H]

Identifier: 209550121

GI number: 209550121

Start: 2570194

End: 2571930

Strand: Reverse

Name: degP [H]

Synonym: Rleg2_2539

Alternate gene names: 209550121

Gene position: 2571930-2570194 (Counterclockwise)

Preceding gene: 209550122

Following gene: 209550119

Centisome position: 56.68

GC content: 63.62

Gene sequence:

>1737_bases
ATGGCCCCCACGAATCGCTCGCCCTTCAGACGAACGCTCGCGCTTATGGCCAGCGCTGCAATTCTTGCGCATGCTGGCAT
GAACGGGGTCGCCTATGCGCAAACCGCGCCGCAGACGACGGCGCCCGGCGTTGCTACACCCGCTCCGGCTACTCCGGAAA
CGGCTGCTCCTGCGCCGACGCCGCCTGCAACGGCTGCACCGCAGCCGACCCCGCAAATGCAGGCCGCAACCCCGAACAAC
GGTCCCGCTTCGGTCGCCGATCTCGCCGAAGGGCTGCTCGACGCCGTGGTCAACATCTCGACCTCGCAGAATGTGAAGGA
TGACGAGGGCGTCGGTCCGGCGCCGCGCGCGCCCGACGGCTCGCCGTTCCAGGAGTTCTTCAACGACTTCTTCGACAAGA
AGCAGGGCAACAAGGGCCCGAACCACAATGTCAGCTCGCTCGGCTCCGGCTTCGTCATCGACCCGGCCGGCTATATCGTC
ACCAACAACCATGTGATCGAGGGCGCCGACGACATCGAGATCAATTTCGCCAATGGTTCGAAGCTCAAGGCGAAACTGAT
CGGCACGGATACGAAGACCGATCTTTCGGTGCTGAAGGTCGAGCCGAAGGCACCGCTGAAATCGGTGAAATTCGGCGATT
CCAGCACCATGCGCATCGGCGACTGGGTGATGGCGATCGGCAATCCGTTCGGCTTCGGCGGTTCGGTGACGGTCGGCATC
ATTTCCGGGCGCGGCCGCAACATCAATGCTGGCCCCTATGACAACTTCATTCAGACGGATGCCGCGATCAACAAGGGCAA
TTCCGGCGGACCGCTCTTCAACATGAAGGGTGAGGTGATCGGCATCAATACGGCGATCATTTCGCCGAGCGGCGGCTCGA
TCGGCATCGGCTTCTCGGTGCCTTCAGAGCTTGCCTCCGGCGTCGTCGATCAATTGCGCGAATATGGTGAGACGCGGCGC
GGCTGGCTCGGTGTGCGCATCCAGCCGGTCACCGACGATATCGCTGACAGTCTCGGGCTCGACACTGCCAAGGGTGCTCT
GGTCGCCGGCGTCATCAAGGGCGGCCCGGTCGACGACGGTTCGATCAAGGCGGGTGACGTCATTTTGAAATTCGACGGCA
AGACCGTCAGCGAAATGCGCGATCTGCCGCGCGTCGTGGCGGAAAGCTCGGTTGGCAAGGAAGTCGACGTGGTGGTGCTG
CGCGACGGCAAGGAGCAGACCGTTAAGGTGAAACTCGGCCGGCTCGAAGACAGCGACCAGGCGGCAGCATCCGGCGATGC
GGCGCCCGACGGTTCGCAGGATGACGGCGTGATCACCCCGGACCCCGGCGAGAACAACGACATGGACGAGCCGGACTCCG
GCGATCAGGCCCAGCCGGCACCAGGCGCGCCCACGCCGGACCAACACCAGGGCCAGGTGTCACCGGATGCATCAACACCG
AAGAACGTGCTCGGCCTGTCGCTGTCGCTTTTGAGCGCCGAGACGCGCAAGGCTTTCGGCATTGCCGAGAGCGTCGACGG
TGTCGTCGTGACGGAGGTGACACCCGGCTCCGCCTCGGCCGAAAAAGGGCTGAAGCCCGGCGACGTGATCGTGGAAGTGG
CGCAGGAGTTTATGAAGTCGCCGGACGCGGTCGCTGCCAAGGTGAAGTCGCTGAAGCAGGAAGGCCGCCGCAACGCCCAA
CTGATGATCGCATCGGCAAATGGTGATCTGCGGTTTGTGGCGGTGCCAATGGAGTAA

Upstream 100 bases:

>100_bases
CGTATTGCACGGGGATTTCGCGAAAAGGTGATTTCGCCCTCCATCATTCCGCCTTATGCTGGTGCTCAATGTGCGCATTT
ACCCCTTATGAGGAAGCTTG

Downstream 100 bases:

>100_bases
GGGGGACGGCGGCGACTAGCCGCCCCTTGCTGTTCTCGCTCAACCTCTCCTCCGTCATTCCTGTGCTTGTCACAGGAATC
CAGCCACCGCGCGTCTGCGC

Product: protease Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 578; Mature: 577

Protein sequence:

>578_residues
MAPTNRSPFRRTLALMASAAILAHAGMNGVAYAQTAPQTTAPGVATPAPATPETAAPAPTPPATAAPQPTPQMQAATPNN
GPASVADLAEGLLDAVVNISTSQNVKDDEGVGPAPRAPDGSPFQEFFNDFFDKKQGNKGPNHNVSSLGSGFVIDPAGYIV
TNNHVIEGADDIEINFANGSKLKAKLIGTDTKTDLSVLKVEPKAPLKSVKFGDSSTMRIGDWVMAIGNPFGFGGSVTVGI
ISGRGRNINAGPYDNFIQTDAAINKGNSGGPLFNMKGEVIGINTAIISPSGGSIGIGFSVPSELASGVVDQLREYGETRR
GWLGVRIQPVTDDIADSLGLDTAKGALVAGVIKGGPVDDGSIKAGDVILKFDGKTVSEMRDLPRVVAESSVGKEVDVVVL
RDGKEQTVKVKLGRLEDSDQAAASGDAAPDGSQDDGVITPDPGENNDMDEPDSGDQAQPAPGAPTPDQHQGQVSPDASTP
KNVLGLSLSLLSAETRKAFGIAESVDGVVVTEVTPGSASAEKGLKPGDVIVEVAQEFMKSPDAVAAKVKSLKQEGRRNAQ
LMIASANGDLRFVAVPME

Sequences:

>Translated_578_residues
MAPTNRSPFRRTLALMASAAILAHAGMNGVAYAQTAPQTTAPGVATPAPATPETAAPAPTPPATAAPQPTPQMQAATPNN
GPASVADLAEGLLDAVVNISTSQNVKDDEGVGPAPRAPDGSPFQEFFNDFFDKKQGNKGPNHNVSSLGSGFVIDPAGYIV
TNNHVIEGADDIEINFANGSKLKAKLIGTDTKTDLSVLKVEPKAPLKSVKFGDSSTMRIGDWVMAIGNPFGFGGSVTVGI
ISGRGRNINAGPYDNFIQTDAAINKGNSGGPLFNMKGEVIGINTAIISPSGGSIGIGFSVPSELASGVVDQLREYGETRR
GWLGVRIQPVTDDIADSLGLDTAKGALVAGVIKGGPVDDGSIKAGDVILKFDGKTVSEMRDLPRVVAESSVGKEVDVVVL
RDGKEQTVKVKLGRLEDSDQAAASGDAAPDGSQDDGVITPDPGENNDMDEPDSGDQAQPAPGAPTPDQHQGQVSPDASTP
KNVLGLSLSLLSAETRKAFGIAESVDGVVVTEVTPGSASAEKGLKPGDVIVEVAQEFMKSPDAVAAKVKSLKQEGRRNAQ
LMIASANGDLRFVAVPME
>Mature_577_residues
APTNRSPFRRTLALMASAAILAHAGMNGVAYAQTAPQTTAPGVATPAPATPETAAPAPTPPATAAPQPTPQMQAATPNNG
PASVADLAEGLLDAVVNISTSQNVKDDEGVGPAPRAPDGSPFQEFFNDFFDKKQGNKGPNHNVSSLGSGFVIDPAGYIVT
NNHVIEGADDIEINFANGSKLKAKLIGTDTKTDLSVLKVEPKAPLKSVKFGDSSTMRIGDWVMAIGNPFGFGGSVTVGII
SGRGRNINAGPYDNFIQTDAAINKGNSGGPLFNMKGEVIGINTAIISPSGGSIGIGFSVPSELASGVVDQLREYGETRRG
WLGVRIQPVTDDIADSLGLDTAKGALVAGVIKGGPVDDGSIKAGDVILKFDGKTVSEMRDLPRVVAESSVGKEVDVVVLR
DGKEQTVKVKLGRLEDSDQAAASGDAAPDGSQDDGVITPDPGENNDMDEPDSGDQAQPAPGAPTPDQHQGQVSPDASTPK
NVLGLSLSLLSAETRKAFGIAESVDGVVVTEVTPGSASAEKGLKPGDVIVEVAQEFMKSPDAVAAKVKSLKQEGRRNAQL
MIASANGDLRFVAVPME

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=278, Percent_Identity=33.8129496402878, Blast_Score=150, Evalue=4e-36,
Organism=Homo sapiens, GI22129776, Length=269, Percent_Identity=33.8289962825279, Blast_Score=149, Evalue=9e-36,
Organism=Homo sapiens, GI24308541, Length=263, Percent_Identity=31.5589353612167, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI7019477, Length=281, Percent_Identity=33.8078291814947, Blast_Score=130, Evalue=3e-30,
Organism=Escherichia coli, GI1786356, Length=368, Percent_Identity=39.1304347826087, Blast_Score=247, Evalue=2e-66,
Organism=Escherichia coli, GI1789629, Length=374, Percent_Identity=37.9679144385027, Blast_Score=239, Evalue=4e-64,
Organism=Escherichia coli, GI1789630, Length=287, Percent_Identity=39.0243902439024, Blast_Score=179, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24646839, Length=294, Percent_Identity=30.2721088435374, Blast_Score=134, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 59394; Mature: 59263

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPTNRSPFRRTLALMASAAILAHAGMNGVAYAQTAPQTTAPGVATPAPATPETAAPAPT
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
PPATAAPQPTPQMQAATPNNGPASVADLAEGLLDAVVNISTSQNVKDDEGVGPAPRAPDG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
SPFQEFFNDFFDKKQGNKGPNHNVSSLGSGFVIDPAGYIVTNNHVIEGADDIEINFANGS
CHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEECCCCEEEECCEEECCCCCEEEEECCCC
KLKAKLIGTDTKTDLSVLKVEPKAPLKSVKFGDSSTMRIGDWVMAIGNPFGFGGSVTVGI
EEEEEEECCCCCCCEEEEEECCCCCCCCEECCCCCCEEECEEEEEECCCCCCCCEEEEEE
ISGRGRNINAGPYDNFIQTDAAINKGNSGGPLFNMKGEVIGINTAIISPSGGSIGIGFSV
EECCCCCCCCCCCCCHHHCCHHHCCCCCCCCEEECCCCEEEEEEEEECCCCCCEEECCCC
PSELASGVVDQLREYGETRRGWLGVRIQPVTDDIADSLGLDTAKGALVAGVIKGGPVDDG
HHHHHHHHHHHHHHHHHHHCCEEEEEEEECCHHHHHHCCCCCCCCCEEEEEECCCCCCCC
SIKAGDVILKFDGKTVSEMRDLPRVVAESSVGKEVDVVVLRDGKEQTVKVKLGRLEDSDQ
CEEECCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEEEECCCCCCH
AAASGDAAPDGSQDDGVITPDPGENNDMDEPDSGDQAQPAPGAPTPDQHQGQVSPDASTP
HCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
KNVLGLSLSLLSAETRKAFGIAESVDGVVVTEVTPGSASAEKGLKPGDVIVEVAQEFMKS
HHHHHHHHHHHHHHHHHHHCHHHCCCCEEEEEECCCCCHHHCCCCCHHHHHHHHHHHHCC
PDAVAAKVKSLKQEGRRNAQLMIASANGDLRFVAVPME
CHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEECCC
>Mature Secondary Structure 
APTNRSPFRRTLALMASAAILAHAGMNGVAYAQTAPQTTAPGVATPAPATPETAAPAPT
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
PPATAAPQPTPQMQAATPNNGPASVADLAEGLLDAVVNISTSQNVKDDEGVGPAPRAPDG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
SPFQEFFNDFFDKKQGNKGPNHNVSSLGSGFVIDPAGYIVTNNHVIEGADDIEINFANGS
CHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEECCCCEEEECCEEECCCCCEEEEECCCC
KLKAKLIGTDTKTDLSVLKVEPKAPLKSVKFGDSSTMRIGDWVMAIGNPFGFGGSVTVGI
EEEEEEECCCCCCCEEEEEECCCCCCCCEECCCCCCEEECEEEEEECCCCCCCCEEEEEE
ISGRGRNINAGPYDNFIQTDAAINKGNSGGPLFNMKGEVIGINTAIISPSGGSIGIGFSV
EECCCCCCCCCCCCCHHHCCHHHCCCCCCCCEEECCCCEEEEEEEEECCCCCCEEECCCC
PSELASGVVDQLREYGETRRGWLGVRIQPVTDDIADSLGLDTAKGALVAGVIKGGPVDDG
HHHHHHHHHHHHHHHHHHHCCEEEEEEEECCHHHHHHCCCCCCCCCEEEEEECCCCCCCC
SIKAGDVILKFDGKTVSEMRDLPRVVAESSVGKEVDVVVLRDGKEQTVKVKLGRLEDSDQ
CEEECCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEEEECCCCCCH
AAASGDAAPDGSQDDGVITPDPGENNDMDEPDSGDQAQPAPGAPTPDQHQGQVSPDASTP
HCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
KNVLGLSLSLLSAETRKAFGIAESVDGVVVTEVTPGSASAEKGLKPGDVIVEVAQEFMKS
HHHHHHHHHHHHHHHHHHHCHHHCCCCEEEEEECCCCCHHHCCCCCHHHHHHHHHHHHCC
PDAVAAKVKSLKQEGRRNAQLMIASANGDLRFVAVPME
CHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]