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The map label for this gene is resE [H]

Identifier: 209549921

GI number: 209549921

Start: 2397561

End: 2399255

Strand: Reverse

Name: resE [H]

Synonym: Rleg2_2337

Alternate gene names: 209549921

Gene position: 2399255-2397561 (Counterclockwise)

Preceding gene: 209549923

Following gene: 209549920

Centisome position: 52.87

GC content: 61.12

Gene sequence:

>1695_bases
TTGAAGGTCAGGCTAACATCCCACATTACATTCGTCTTGGTGACACTCACCTGTGCGGCGGCTGTGTTGCTGTGCGGATT
TGCGTGGCTCGCCGCCATTAAGGTAGATGATCTCTCGCTGCGCCGGCAGGCCGACTTTGTCCGGCAGGGACTGGAAGAAC
AGATCGCGGCGCTGCCCCGCGAACAGGAAAGCGTCGCCAAATGGGACGACGCCTTCCTTTATGCCAAGCAGCGAAACCAT
GAATGGCTGCTCGACAATATCGGCCGGTGGACGAGCCAGTATTTCGGGCATGACCGGACCTATATCTTCGACGATACCAA
CCGCTTGATGTTTGCATTCCGCGACGGCGCGGATGCCATGCCGCCGCGGCTTGGCAGCGACGACGGCCGAGAAATGACCA
CGCTTGCCGGGGAAATGCGCGCGGTTCTCGTCGAGCAGGCGGCAAAGCCCAGTACCAAACCGCTCGGTCAGCTGGCGACG
GTTCGCACGATCATGATCGGCAATCGGCCGGCCATTGTAAGCGCGCGGCCCATTCTGCCGAGCTCGGCCAGAATGCAGAT
CGAGGCGGGCCAGGAGTTCATCGCCGTCTCGGTCAAGTTCATCGATGGAAAAGCCGCCGAAAGCATCGCCCATTATGCGC
GCCTCGAAGGCTTGCATTTCGCGCCGAAAAGCAAGGACGAACGGGCCCAAGTGCCGGTGTTGTCGCATGACGGCGGCACG
ATCGGCTATCTCGTATGGCCGCCGATCCTGCCCGGATTCATGCTCTTTCAACAGATCGCGCCGGCTGGGCTTGGCTGCCT
GGCGCTGCTGATCGCTGTCGTCTTCTGGCTCGGACGCGGTCTGCATCGGACCTCGCTGACCCTGCTGGACAGCCAGGCTG
AGCTCACCCACCACCGCAACCACCTGGAAGAAATGGTGGCCGATCGAACGGCCGAGATCGAACGGCAGAGGGAGGAGCTG
GACCGGCTGTTGGTGCACGAGCGCCAGGTGAATGCGCTCCAGCGCCAGTTCGTCGCCATGGCGTCGCACGAGTTTCGCAC
ACCGCTCGCAATCATCGACGCCGCAGCCCAGCGGCTCTGCCGCTCGACCACCAATGTCGGCGGCGACTACGTTCACGAAA
AAGCCGGCGTGATCCGCAGCGCGGTGGTGCGCATGGTCGATCTGATGGAGAGCATCCTCGCCAGTGGCCGGCTCGAAACC
GGACAGATTACATTGAAGCGGAGCGAGGGCGATCTGAAAGCCTTGCTCGTCACCTGCTGCGACAGACAGCGCCACCTCAG
CCGCTCGCATCTGTTCCATCTCGATCTTGAGGCGATACCCGAGGGTTTGACGTTCGACCGCAGCGCGATGGAACAGGTCT
TCACCAACCTGATTTCGAACGCCGTCAAATATTCGCCCAATGCGCCTAATATCCATGTTCGCGCCCGGGTTGATGAAAAG
ACGCTGGAGATCGCTATCGCCGACAGCGGCATCGGCATGGATGCGGATGATCTGCCGAAGCTGTTTCAACCCTATTACCG
CGCCCGCAGCGCGACGGGCATTGCCGGCACCGGCATCGGGCTCAACGTCGTCAAGCAGGTCGTCGAACTGCATGGCGGCA
CCGTCGAGGTGACGAGCGAGCTCGGCAAGGGCACAACATTTATCATTCGTCTGCCAATAGGGTCTCTATTGTCGGATCAA
CACGTCGCAGCTTAG

Upstream 100 bases:

>100_bases
GGAGACATGTCGCGGGGCGCAGGGGAGCGCATAATTCACGGTCCGTCAACCTTTGCGTGTCAATTTCTCGGCAGCGGGCG
CCGTCAAAAGGTTGCAGATA

Downstream 100 bases:

>100_bases
GGAAAAGCTTATGGTTACAGTCCTGTGCATAGAAGATGAAGTCGAGATCCGGAACCTCCTCGTCGAAGAGTTGACCGAAG
CCGGCTACAGGACGCTCGAG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 564; Mature: 564

Protein sequence:

>564_residues
MKVRLTSHITFVLVTLTCAAAVLLCGFAWLAAIKVDDLSLRRQADFVRQGLEEQIAALPREQESVAKWDDAFLYAKQRNH
EWLLDNIGRWTSQYFGHDRTYIFDDTNRLMFAFRDGADAMPPRLGSDDGREMTTLAGEMRAVLVEQAAKPSTKPLGQLAT
VRTIMIGNRPAIVSARPILPSSARMQIEAGQEFIAVSVKFIDGKAAESIAHYARLEGLHFAPKSKDERAQVPVLSHDGGT
IGYLVWPPILPGFMLFQQIAPAGLGCLALLIAVVFWLGRGLHRTSLTLLDSQAELTHHRNHLEEMVADRTAEIERQREEL
DRLLVHERQVNALQRQFVAMASHEFRTPLAIIDAAAQRLCRSTTNVGGDYVHEKAGVIRSAVVRMVDLMESILASGRLET
GQITLKRSEGDLKALLVTCCDRQRHLSRSHLFHLDLEAIPEGLTFDRSAMEQVFTNLISNAVKYSPNAPNIHVRARVDEK
TLEIAIADSGIGMDADDLPKLFQPYYRARSATGIAGTGIGLNVVKQVVELHGGTVEVTSELGKGTTFIIRLPIGSLLSDQ
HVAA

Sequences:

>Translated_564_residues
MKVRLTSHITFVLVTLTCAAAVLLCGFAWLAAIKVDDLSLRRQADFVRQGLEEQIAALPREQESVAKWDDAFLYAKQRNH
EWLLDNIGRWTSQYFGHDRTYIFDDTNRLMFAFRDGADAMPPRLGSDDGREMTTLAGEMRAVLVEQAAKPSTKPLGQLAT
VRTIMIGNRPAIVSARPILPSSARMQIEAGQEFIAVSVKFIDGKAAESIAHYARLEGLHFAPKSKDERAQVPVLSHDGGT
IGYLVWPPILPGFMLFQQIAPAGLGCLALLIAVVFWLGRGLHRTSLTLLDSQAELTHHRNHLEEMVADRTAEIERQREEL
DRLLVHERQVNALQRQFVAMASHEFRTPLAIIDAAAQRLCRSTTNVGGDYVHEKAGVIRSAVVRMVDLMESILASGRLET
GQITLKRSEGDLKALLVTCCDRQRHLSRSHLFHLDLEAIPEGLTFDRSAMEQVFTNLISNAVKYSPNAPNIHVRARVDEK
TLEIAIADSGIGMDADDLPKLFQPYYRARSATGIAGTGIGLNVVKQVVELHGGTVEVTSELGKGTTFIIRLPIGSLLSDQ
HVAA
>Mature_564_residues
MKVRLTSHITFVLVTLTCAAAVLLCGFAWLAAIKVDDLSLRRQADFVRQGLEEQIAALPREQESVAKWDDAFLYAKQRNH
EWLLDNIGRWTSQYFGHDRTYIFDDTNRLMFAFRDGADAMPPRLGSDDGREMTTLAGEMRAVLVEQAAKPSTKPLGQLAT
VRTIMIGNRPAIVSARPILPSSARMQIEAGQEFIAVSVKFIDGKAAESIAHYARLEGLHFAPKSKDERAQVPVLSHDGGT
IGYLVWPPILPGFMLFQQIAPAGLGCLALLIAVVFWLGRGLHRTSLTLLDSQAELTHHRNHLEEMVADRTAEIERQREEL
DRLLVHERQVNALQRQFVAMASHEFRTPLAIIDAAAQRLCRSTTNVGGDYVHEKAGVIRSAVVRMVDLMESILASGRLET
GQITLKRSEGDLKALLVTCCDRQRHLSRSHLFHLDLEAIPEGLTFDRSAMEQVFTNLISNAVKYSPNAPNIHVRARVDEK
TLEIAIADSGIGMDADDLPKLFQPYYRARSATGIAGTGIGLNVVKQVVELHGGTVEVTSELGKGTTFIIRLPIGSLLSDQ
HVAA

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=238, Percent_Identity=30.2521008403361, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1789149, Length=283, Percent_Identity=25.7950530035336, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1786912, Length=239, Percent_Identity=28.4518828451883, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1788393, Length=248, Percent_Identity=25, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI145693157, Length=279, Percent_Identity=24.3727598566308, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1786600, Length=230, Percent_Identity=26.9565217391304, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081816, Length=271, Percent_Identity=27.6752767527675, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=30, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1788279, Length=218, Percent_Identity=28.4403669724771, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788713, Length=227, Percent_Identity=26.8722466960352, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1786783, Length=258, Percent_Identity=27.1317829457364, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1790861, Length=299, Percent_Identity=25.752508361204, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1788549, Length=252, Percent_Identity=26.5873015873016, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI87082128, Length=219, Percent_Identity=21.9178082191781, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787894, Length=257, Percent_Identity=24.9027237354086, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 62356; Mature: 62356

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVRLTSHITFVLVTLTCAAAVLLCGFAWLAAIKVDDLSLRRQADFVRQGLEEQIAALPR
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHCCC
EQESVAKWDDAFLYAKQRNHEWLLDNIGRWTSQYFGHDRTYIFDDTNRLMFAFRDGADAM
CHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEECCCCCC
PPRLGSDDGREMTTLAGEMRAVLVEQAAKPSTKPLGQLATVRTIMIGNRPAIVSARPILP
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHEEEECCCCCEEECCCCCC
SSARMQIEAGQEFIAVSVKFIDGKAAESIAHYARLEGLHFAPKSKDERAQVPVLSHDGGT
CCCCEEEECCCEEEEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCE
IGYLVWPPILPGFMLFQQIAPAGLGCLALLIAVVFWLGRGLHRTSLTLLDSQAELTHHRN
EEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHEEECCHHHHHHHHH
HLEEMVADRTAEIERQREELDRLLVHERQVNALQRQFVAMASHEFRTPLAIIDAAAQRLC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
RSTTNVGGDYVHEKAGVIRSAVVRMVDLMESILASGRLETGQITLKRSEGDLKALLVTCC
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHH
DRQRHLSRSHLFHLDLEAIPEGLTFDRSAMEQVFTNLISNAVKYSPNAPNIHVRARVDEK
HHHHHCCHHHEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCC
TLEIAIADSGIGMDADDLPKLFQPYYRARSATGIAGTGIGLNVVKQVVELHGGTVEVTSE
EEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEHH
LGKGTTFIIRLPIGSLLSDQHVAA
CCCCCEEEEEECCHHHHCCCCCCC
>Mature Secondary Structure
MKVRLTSHITFVLVTLTCAAAVLLCGFAWLAAIKVDDLSLRRQADFVRQGLEEQIAALPR
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHCCC
EQESVAKWDDAFLYAKQRNHEWLLDNIGRWTSQYFGHDRTYIFDDTNRLMFAFRDGADAM
CHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEECCCCCC
PPRLGSDDGREMTTLAGEMRAVLVEQAAKPSTKPLGQLATVRTIMIGNRPAIVSARPILP
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHEEEECCCCCEEECCCCCC
SSARMQIEAGQEFIAVSVKFIDGKAAESIAHYARLEGLHFAPKSKDERAQVPVLSHDGGT
CCCCEEEECCCEEEEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCE
IGYLVWPPILPGFMLFQQIAPAGLGCLALLIAVVFWLGRGLHRTSLTLLDSQAELTHHRN
EEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHEEECCHHHHHHHHH
HLEEMVADRTAEIERQREELDRLLVHERQVNALQRQFVAMASHEFRTPLAIIDAAAQRLC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
RSTTNVGGDYVHEKAGVIRSAVVRMVDLMESILASGRLETGQITLKRSEGDLKALLVTCC
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHH
DRQRHLSRSHLFHLDLEAIPEGLTFDRSAMEQVFTNLISNAVKYSPNAPNIHVRARVDEK
HHHHHCCHHHEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCC
TLEIAIADSGIGMDADDLPKLFQPYYRARSATGIAGTGIGLNVVKQVVELHGGTVEVTSE
EEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEHH
LGKGTTFIIRLPIGSLLSDQHVAA
CCCCCEEEEEECCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]