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The map label for this gene is zraS [C]

Identifier: 209549636

GI number: 209549636

Start: 2105018

End: 2107093

Strand: Reverse

Name: zraS [C]

Synonym: Rleg2_2043

Alternate gene names: 209549636

Gene position: 2107093-2105018 (Counterclockwise)

Preceding gene: 209549637

Following gene: 209549632

Centisome position: 46.43

GC content: 61.66

Gene sequence:

>2076_bases
TTGACCGATCAGACCGGATTACCTTCGATAGCCGTTGCCGATCTGAGGCAGTTCGCCGCGTCACTCGATGAGGAAATCGC
GGTCGGCGTCCTGACCGAAGAGGCCGTCCGCGGAAATGACCTCAGACCGATTGCTGCCTGGGTTGCCGCCCAACCGAGTT
GGTCCGACCTGCCATTCATCGTCCTGACCCAGCGCGGCGGGGGACCTGAACGAAACCCTGCCGCCGCCAAGCTTTCCGAA
ATCCTTGGCAATGTGACCTTTCTGGAGAGGCCCTTCCATGCGACGTCCTTCATCAGTGTTGCGCGGACTGCATTAAGGGG
GCGCCTGCGCCAGTATGAAGCGCGCGCCCGGCTGGAGGCATTAGGCGAGGGAGAGCGGCGGTTGCAGACAGCACTTGCGG
CCGGCCGTCTCGGGGCGTGGGAGCTGGAACTATCCTCGATGGCCTTGTCTGCATCGGCGACCTGCAAAGCTGTCTTCGGT
CGAGAGCCGGACGTTGAGGTGACGCGTGATGATCTGATCGCCAGCATCCACCCTGACGATCGCGACCTTGTGCTGACACG
CCTTCGCGAGACGATCGATACGGGACGCGATTATTCGATCGAGCATAGAACGATCTGGCCGGATGGATCAGAGCATTGGA
CCGAGGTTCATGCCCAGCTTTATGCCGACAGATATGGCTCTGCGCGGAAGCTTGTCGGGGTCTGCTCCGATACCACTGTT
CGCAAGACCATTGAGGAGAATCTGAGACGGCTCAACGAGAATCTCGAGGAGCGCGTCAGGGAAAGGACCAGGGAAGTCAA
CGCTGCCCACCAGACGTTGCTTGAAGAGGTCGCCCAGCGTGAGAGAGCCGAAGAGCAGCTCCGCCAATCCCAGAAAATGG
AAGCGATCGGTCAACTTACGGGCGGCGTTGCCCACGACTTCAACAATCTGTTGATGGTGGTTCTCGGAAATCTGGAGCTG
CTCGGCAAACATTTTGCCGGAGATGGCAAGGCGATGCGGCTGGTCGACGGGGCGCTTCAGGGCGCGCGCCGAGGGGCGGC
GCTGACACAGCGTTTGCTTGCCTTTGCCAGACAGCAGGATCTGCAGGTCAAGCCCGTCGATCTGGCCGATCTGGTCTCCG
GGATGAACGACTTGCTGCGGCGCTCGGTCGGATCCTCGATCAGTATCGAGACCACCTTGCCGGCGAAATTGCCGCCGGCG
CTGGTCGATGCGAACCAGCTCGAACTGGCGCTGCTCAACCTTGCGGTCAATGCCCGCGATGCGATGCCGGATGGCGGAAT
GTTGTCGATTTCGCTACGCGAGGAGCAGGTTGTCGGCAATGACGGCGATCTCGGCGAGGGAGCCTATCTCGTGTTGGCGG
TGGCCGACAGCGGCACGGGCATGGATGCCGAGACGCTGAAGAAGGCCGTCGATCCGTTTTTCTCGACCAAGGAACTCGGA
AAGGGTACTGGCCTCGGCCTTTCGATGATCCATGGACTTGCCGTTCAGCTCAATGGCGCGCTTGTTCTGACAAGCGAACT
TGGCGTAGGGACGACCGCCGAATTGTGGCTTCCGGCGACCGAACAGCGCGCCGAGCGGCCGGCTGAGGCTGTGCTCTCCA
CACCGCAGGCTGCATCCCGACTGAAGATCCTTCTGGTCGACGACGACGCCTTGATCGCCATGAGTTCGGTCGACATGCTC
GAAGATCTCGGCCACGAGGTCGTCGAGGCAAATTCCGGCGCGCAGGCGCTCGAGCTGATCGGGAGCGGCCAGCATTTCGA
TCTGATGATCACCGACTATTCGATGCCCGGCATGACAGGCGCACAGCTCGCCGAGGCGGCGCGGGCCATTCATCCGGCGC
TGCCGATCGTGCTGGCGACCGGCTATGCCGATCTTCCCGCCGGCACCGACATTGATCTACCGAGACTGGCGAAACCCTAT
AACCAGGACCAGCTTGCCAGGGAAATCGCTAAGGCGGTGGCAGGCGAAGCGAATCCGCCTCTCAGGTTCGATAGCCGGAT
AAGCGGCTCAGGGGCGGGGCGTCTCGAGACCGACGATGCCGGCGATGAAATCGGCGATGGCGCCTGTGTCGTCTAG

Upstream 100 bases:

>100_bases
TTGCCAACCGACAACAAGGACGGCGGCAATTCTTAATTTCCCGAACCCGAAGGCCCTGATCTACGCACCGGCCGGACGCG
ACGCACAGGTCGCCGCATCA

Downstream 100 bases:

>100_bases
ATCGAAGACCGGCAGGGCCGTATCCGTCACGGCGTGGTCGGCGGCGATGGCGCAGATATGGGGATCGCTCGGCGCCAGCG
GCTGGCGGTTGGCGGCCTCC

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 691; Mature: 690

Protein sequence:

>691_residues
MTDQTGLPSIAVADLRQFAASLDEEIAVGVLTEEAVRGNDLRPIAAWVAAQPSWSDLPFIVLTQRGGGPERNPAAAKLSE
ILGNVTFLERPFHATSFISVARTALRGRLRQYEARARLEALGEGERRLQTALAAGRLGAWELELSSMALSASATCKAVFG
REPDVEVTRDDLIASIHPDDRDLVLTRLRETIDTGRDYSIEHRTIWPDGSEHWTEVHAQLYADRYGSARKLVGVCSDTTV
RKTIEENLRRLNENLEERVRERTREVNAAHQTLLEEVAQRERAEEQLRQSQKMEAIGQLTGGVAHDFNNLLMVVLGNLEL
LGKHFAGDGKAMRLVDGALQGARRGAALTQRLLAFARQQDLQVKPVDLADLVSGMNDLLRRSVGSSISIETTLPAKLPPA
LVDANQLELALLNLAVNARDAMPDGGMLSISLREEQVVGNDGDLGEGAYLVLAVADSGTGMDAETLKKAVDPFFSTKELG
KGTGLGLSMIHGLAVQLNGALVLTSELGVGTTAELWLPATEQRAERPAEAVLSTPQAASRLKILLVDDDALIAMSSVDML
EDLGHEVVEANSGAQALELIGSGQHFDLMITDYSMPGMTGAQLAEAARAIHPALPIVLATGYADLPAGTDIDLPRLAKPY
NQDQLAREIAKAVAGEANPPLRFDSRISGSGAGRLETDDAGDEIGDGACVV

Sequences:

>Translated_691_residues
MTDQTGLPSIAVADLRQFAASLDEEIAVGVLTEEAVRGNDLRPIAAWVAAQPSWSDLPFIVLTQRGGGPERNPAAAKLSE
ILGNVTFLERPFHATSFISVARTALRGRLRQYEARARLEALGEGERRLQTALAAGRLGAWELELSSMALSASATCKAVFG
REPDVEVTRDDLIASIHPDDRDLVLTRLRETIDTGRDYSIEHRTIWPDGSEHWTEVHAQLYADRYGSARKLVGVCSDTTV
RKTIEENLRRLNENLEERVRERTREVNAAHQTLLEEVAQRERAEEQLRQSQKMEAIGQLTGGVAHDFNNLLMVVLGNLEL
LGKHFAGDGKAMRLVDGALQGARRGAALTQRLLAFARQQDLQVKPVDLADLVSGMNDLLRRSVGSSISIETTLPAKLPPA
LVDANQLELALLNLAVNARDAMPDGGMLSISLREEQVVGNDGDLGEGAYLVLAVADSGTGMDAETLKKAVDPFFSTKELG
KGTGLGLSMIHGLAVQLNGALVLTSELGVGTTAELWLPATEQRAERPAEAVLSTPQAASRLKILLVDDDALIAMSSVDML
EDLGHEVVEANSGAQALELIGSGQHFDLMITDYSMPGMTGAQLAEAARAIHPALPIVLATGYADLPAGTDIDLPRLAKPY
NQDQLAREIAKAVAGEANPPLRFDSRISGSGAGRLETDDAGDEIGDGACVV
>Mature_690_residues
TDQTGLPSIAVADLRQFAASLDEEIAVGVLTEEAVRGNDLRPIAAWVAAQPSWSDLPFIVLTQRGGGPERNPAAAKLSEI
LGNVTFLERPFHATSFISVARTALRGRLRQYEARARLEALGEGERRLQTALAAGRLGAWELELSSMALSASATCKAVFGR
EPDVEVTRDDLIASIHPDDRDLVLTRLRETIDTGRDYSIEHRTIWPDGSEHWTEVHAQLYADRYGSARKLVGVCSDTTVR
KTIEENLRRLNENLEERVRERTREVNAAHQTLLEEVAQRERAEEQLRQSQKMEAIGQLTGGVAHDFNNLLMVVLGNLELL
GKHFAGDGKAMRLVDGALQGARRGAALTQRLLAFARQQDLQVKPVDLADLVSGMNDLLRRSVGSSISIETTLPAKLPPAL
VDANQLELALLNLAVNARDAMPDGGMLSISLREEQVVGNDGDLGEGAYLVLAVADSGTGMDAETLKKAVDPFFSTKELGK
GTGLGLSMIHGLAVQLNGALVLTSELGVGTTAELWLPATEQRAERPAEAVLSTPQAASRLKILLVDDDALIAMSSVDMLE
DLGHEVVEANSGAQALELIGSGQHFDLMITDYSMPGMTGAQLAEAARAIHPALPIVLATGYADLPAGTDIDLPRLAKPYN
QDQLAREIAKAVAGEANPPLRFDSRISGSGAGRLETDDAGDEIGDGACVV

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=251, Percent_Identity=30.6772908366534, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1788713, Length=338, Percent_Identity=27.2189349112426, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI48994928, Length=423, Percent_Identity=25.7683215130024, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788549, Length=251, Percent_Identity=26.2948207171315, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081816, Length=238, Percent_Identity=27.7310924369748, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI145693157, Length=286, Percent_Identity=25.8741258741259, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 74207; Mature: 74076

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQTGLPSIAVADLRQFAASLDEEIAVGVLTEEAVRGNDLRPIAAWVAAQPSWSDLPFI
CCCCCCCCHHHHHHHHHHHHCCCHHHEEEEEEHHHHCCCCCCHHHHHHCCCCCCCCCCEE
VLTQRGGGPERNPAAAKLSEILGNVTFLERPFHATSFISVARTALRGRLRQYEARARLEA
EEEECCCCCCCCHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGEGERRLQTALAAGRLGAWELELSSMALSASATCKAVFGREPDVEVTRDDLIASIHPDD
HCCHHHHHHHHHHHCCCCEEEEEHHHHHHCCCCHHHHHCCCCCCCEECHHHEEEECCCCC
RDLVLTRLRETIDTGRDYSIEHRTIWPDGSEHWTEVHAQLYADRYGSARKLVGVCSDTTV
HHHHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHCCCHHHHHEECCCHHH
RKTIEENLRRLNENLEERVRERTREVNAAHQTLLEEVAQRERAEEQLRQSQKMEAIGQLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGVAHDFNNLLMVVLGNLELLGKHFAGDGKAMRLVDGALQGARRGAALTQRLLAFARQQD
CHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LQVKPVDLADLVSGMNDLLRRSVGSSISIETTLPAKLPPALVDANQLELALLNLAVNARD
CCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHCCCCHHHEEHHHHHCCCCC
AMPDGGMLSISLREEQVVGNDGDLGEGAYLVLAVADSGTGMDAETLKKAVDPFFSTKELG
CCCCCCEEEEEEEHHHCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCHHHHC
KGTGLGLSMIHGLAVQLNGALVLTSELGVGTTAELWLPATEQRAERPAEAVLSTPQAASR
CCCCCHHHHHHHHHEEECCEEEEEECCCCCCCHHEECCCHHHHHCCCHHHHHCCCCCCCC
LKILLVDDDALIAMSSVDMLEDLGHEVVEANSGAQALELIGSGQHFDLMITDYSMPGMTG
EEEEEECCCCEEEHHHHHHHHHCCHHHHHCCCCHHHHHHHCCCCEEEEEEEECCCCCCCH
AQLAEAARAIHPALPIVLATGYADLPAGTDIDLPRLAKPYNQDQLAREIAKAVAGEANPP
HHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCCC
LRFDSRISGSGAGRLETDDAGDEIGDGACVV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDQTGLPSIAVADLRQFAASLDEEIAVGVLTEEAVRGNDLRPIAAWVAAQPSWSDLPFI
CCCCCCCHHHHHHHHHHHHCCCHHHEEEEEEHHHHCCCCCCHHHHHHCCCCCCCCCCEE
VLTQRGGGPERNPAAAKLSEILGNVTFLERPFHATSFISVARTALRGRLRQYEARARLEA
EEEECCCCCCCCHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGEGERRLQTALAAGRLGAWELELSSMALSASATCKAVFGREPDVEVTRDDLIASIHPDD
HCCHHHHHHHHHHHCCCCEEEEEHHHHHHCCCCHHHHHCCCCCCCEECHHHEEEECCCCC
RDLVLTRLRETIDTGRDYSIEHRTIWPDGSEHWTEVHAQLYADRYGSARKLVGVCSDTTV
HHHHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHCCCHHHHHEECCCHHH
RKTIEENLRRLNENLEERVRERTREVNAAHQTLLEEVAQRERAEEQLRQSQKMEAIGQLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGVAHDFNNLLMVVLGNLELLGKHFAGDGKAMRLVDGALQGARRGAALTQRLLAFARQQD
CHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LQVKPVDLADLVSGMNDLLRRSVGSSISIETTLPAKLPPALVDANQLELALLNLAVNARD
CCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHCCCCHHHEEHHHHHCCCCC
AMPDGGMLSISLREEQVVGNDGDLGEGAYLVLAVADSGTGMDAETLKKAVDPFFSTKELG
CCCCCCEEEEEEEHHHCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCHHHHC
KGTGLGLSMIHGLAVQLNGALVLTSELGVGTTAELWLPATEQRAERPAEAVLSTPQAASR
CCCCCHHHHHHHHHEEECCEEEEEECCCCCCCHHEECCCHHHHHCCCHHHHHCCCCCCCC
LKILLVDDDALIAMSSVDMLEDLGHEVVEANSGAQALELIGSGQHFDLMITDYSMPGMTG
EEEEEECCCCEEEHHHHHHHHHCCHHHHHCCCCHHHHHHHCCCCEEEEEEEECCCCCCCH
AQLAEAARAIHPALPIVLATGYADLPAGTDIDLPRLAKPYNQDQLAREIAKAVAGEANPP
HHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCCC
LRFDSRISGSGAGRLETDDAGDEIGDGACVV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA