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The map label for this gene is glpK2 [H]

Identifier: 209549624

GI number: 209549624

Start: 2092680

End: 2094146

Strand: Reverse

Name: glpK2 [H]

Synonym: Rleg2_2031

Alternate gene names: 209549624

Gene position: 2094146-2092680 (Counterclockwise)

Preceding gene: 209549625

Following gene: 209549623

Centisome position: 46.15

GC content: 63.33

Gene sequence:

>1467_bases
ATGCGGGCAATTCTGGCAATCGACCAGGGCACGACCAATTCAAAGGCCGTTCTCGTTTCCGAAAAGGGAGAAATCGTCGG
CAGAGGCTCGGCTCCGGTCGGCATCTCCTATCCGAAACCGGGATGGGTCGAACAGGACCCGCGCCGGCTCTACGCGTCGG
TCTGCGAAGCGATAGACGCCTGCCTGAGGGCCAGCCCGGCTCTCACCATCGAGGCCGTGGCGATTTCCAACCAGCGCGAG
TCCGTCACTGCCTGGGACGCCGAAACGGGAGAAGCACTAGGACCATTGGTCAGCTGGCAGTGCCGCCGAACGGCGCCGGA
TTGCGAGCGTCTCATTGCCAAGGGCCACCTTGACCGGGTGCAGGCGGTCACCGGCCTGCCATTGGATCCGATGTTTCCGG
GTTCGAAATTCCGATGGCTGCTCGACCGTGTTCCGGCCGGACGATCGGTGCGGCTGGGAACGGTCGACAGCTGGCTGGTC
CACTGCCTGACCGGCGGGCGCCGGCATGTTTGCGATGCGTCGAATGCCGCCAGGAGCCAGTTGTTCGATCTGCGGGAGCA
GAGATGGAGCGAGGAGCTTGGCGAGATCTTCGGCGTCGATATCGCGCTCCTTCCCGAGGTGCTCGACAGTTCTGCCGATT
TCGGCAGAACGCAGGGATTGCCGGGGGTGGCGGATGGCACGCCCATCATGGCCGCGATCGGCGACAGCCACGCTGCCCTA
TTCGGTCACGGCGCCTTCACGCCGGGCGACGGCAAGGTGACCTTCGGAACCGGCTCTTCCGTCATGACGACGCTTGCGCA
ATATATTGCCCCGCGCAACGGCGTCACAACCACGGTCGCATGGCGTATCGGGGGAAAGCCGACCTTCGCTTTCGAAGGCA
ATATTCTCGTCTGCGCCGCCAGTCTTCCCTGGATGGCTGATATTCTCGGCCTTGCGGATGTGGCGGCGCTTGTCGAACTT
GCGGAAAGTGCCGAGCCGGGCGGACCCGGCTTCGTGCCGGCATTCGTGGGGCTGGGAGCACCTTACTGGAATGCCGATGC
CCGCGCCCTGTTCTCTCAGATCAACTTCAATACGACGCGGGCGCAAATGGCGCGGTCGGTTACCGATTCCATCGCCTTGC
AGGTGCATGACGTGATTGCGGCCATGCGGGCACAAAGCGGCGGTGCGCTCGGCGCGCTCTATGTGGATGGCGGACCGAGC
CAGAACCGCTTCCTGATGCAGTGTGTCTCCGACCTCATCAACCATCCGGTGATCCAATGCGAAGCACCCGAGGCATCGGC
TTTGGGCGCTGCTTATCTGGCGGGCCTGTCACTTGGTTTGTGGAGCGATCTCGACATGGTCGCGGGGCTGCCGCGAAAGT
CGCAAACCATCCAGCCGCAACCCGTGGATCGAGCGGGGCTGCTCGATAGCTGGAATGATGCGCTCGCCCGCTCGACGGCC
CGCGAAACAAAGGCTAAAGGTGAATAA

Upstream 100 bases:

>100_bases
ACGCAGCGCAGTCGCTGATCAGGCGCAAGTAATTGAGGTCACGTGACCGGCGGGGACGCCTTTTTTCGTCCCGGTCGTCA
CCTGATCCGGGGAGGATAGA

Downstream 100 bases:

>100_bases
AAATTCACTCTGGGATTAGCGATGACTCGCCTCAACGAACTCCGCCTCATTTCAAGGGTCGCCCAGATGTACCATATCGA
GGGGCGGCGGCAGGCGGAGA

Product: carbohydrate kinase FGGY

Products: NA

Alternate protein names: ATP:glycerol 3-phosphotransferase 2; Glycerokinase 2; GK 2 [H]

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MRAILAIDQGTTNSKAVLVSEKGEIVGRGSAPVGISYPKPGWVEQDPRRLYASVCEAIDACLRASPALTIEAVAISNQRE
SVTAWDAETGEALGPLVSWQCRRTAPDCERLIAKGHLDRVQAVTGLPLDPMFPGSKFRWLLDRVPAGRSVRLGTVDSWLV
HCLTGGRRHVCDASNAARSQLFDLREQRWSEELGEIFGVDIALLPEVLDSSADFGRTQGLPGVADGTPIMAAIGDSHAAL
FGHGAFTPGDGKVTFGTGSSVMTTLAQYIAPRNGVTTTVAWRIGGKPTFAFEGNILVCAASLPWMADILGLADVAALVEL
AESAEPGGPGFVPAFVGLGAPYWNADARALFSQINFNTTRAQMARSVTDSIALQVHDVIAAMRAQSGGALGALYVDGGPS
QNRFLMQCVSDLINHPVIQCEAPEASALGAAYLAGLSLGLWSDLDMVAGLPRKSQTIQPQPVDRAGLLDSWNDALARSTA
RETKAKGE

Sequences:

>Translated_488_residues
MRAILAIDQGTTNSKAVLVSEKGEIVGRGSAPVGISYPKPGWVEQDPRRLYASVCEAIDACLRASPALTIEAVAISNQRE
SVTAWDAETGEALGPLVSWQCRRTAPDCERLIAKGHLDRVQAVTGLPLDPMFPGSKFRWLLDRVPAGRSVRLGTVDSWLV
HCLTGGRRHVCDASNAARSQLFDLREQRWSEELGEIFGVDIALLPEVLDSSADFGRTQGLPGVADGTPIMAAIGDSHAAL
FGHGAFTPGDGKVTFGTGSSVMTTLAQYIAPRNGVTTTVAWRIGGKPTFAFEGNILVCAASLPWMADILGLADVAALVEL
AESAEPGGPGFVPAFVGLGAPYWNADARALFSQINFNTTRAQMARSVTDSIALQVHDVIAAMRAQSGGALGALYVDGGPS
QNRFLMQCVSDLINHPVIQCEAPEASALGAAYLAGLSLGLWSDLDMVAGLPRKSQTIQPQPVDRAGLLDSWNDALARSTA
RETKAKGE
>Mature_488_residues
MRAILAIDQGTTNSKAVLVSEKGEIVGRGSAPVGISYPKPGWVEQDPRRLYASVCEAIDACLRASPALTIEAVAISNQRE
SVTAWDAETGEALGPLVSWQCRRTAPDCERLIAKGHLDRVQAVTGLPLDPMFPGSKFRWLLDRVPAGRSVRLGTVDSWLV
HCLTGGRRHVCDASNAARSQLFDLREQRWSEELGEIFGVDIALLPEVLDSSADFGRTQGLPGVADGTPIMAAIGDSHAAL
FGHGAFTPGDGKVTFGTGSSVMTTLAQYIAPRNGVTTTVAWRIGGKPTFAFEGNILVCAASLPWMADILGLADVAALVEL
AESAEPGGPGFVPAFVGLGAPYWNADARALFSQINFNTTRAQMARSVTDSIALQVHDVIAAMRAQSGGALGALYVDGGPS
QNRFLMQCVSDLINHPVIQCEAPEASALGAAYLAGLSLGLWSDLDMVAGLPRKSQTIQPQPVDRAGLLDSWNDALARSTA
RETKAKGE

Specific function: Key enzyme in the regulation of glycerol uptake and metabolism [H]

COG id: COG0554

COG function: function code C; Glycerol kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI4504007, Length=443, Percent_Identity=34.5372460496614, Blast_Score=260, Evalue=2e-69,
Organism=Homo sapiens, GI189409120, Length=443, Percent_Identity=34.5372460496614, Blast_Score=259, Evalue=3e-69,
Organism=Homo sapiens, GI42794763, Length=447, Percent_Identity=34.2281879194631, Blast_Score=257, Evalue=2e-68,
Organism=Homo sapiens, GI41393575, Length=444, Percent_Identity=35.3603603603604, Blast_Score=256, Evalue=4e-68,
Organism=Homo sapiens, GI88196792, Length=504, Percent_Identity=27.5793650793651, Blast_Score=190, Evalue=2e-48,
Organism=Escherichia coli, GI1790361, Length=496, Percent_Identity=37.5, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI1789168, Length=452, Percent_Identity=23.8938053097345, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1789987, Length=493, Percent_Identity=25.1521298174442, Blast_Score=96, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17535599, Length=502, Percent_Identity=31.6733067729084, Blast_Score=226, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI71986140, Length=512, Percent_Identity=25.9765625, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71986147, Length=256, Percent_Identity=32.03125, Blast_Score=116, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6321755, Length=536, Percent_Identity=30.0373134328358, Blast_Score=194, Evalue=2e-50,
Organism=Drosophila melanogaster, GI17864214, Length=507, Percent_Identity=32.1499013806706, Blast_Score=248, Evalue=8e-66,
Organism=Drosophila melanogaster, GI24655555, Length=454, Percent_Identity=31.2775330396476, Blast_Score=228, Evalue=1e-59,
Organism=Drosophila melanogaster, GI24655560, Length=454, Percent_Identity=31.2775330396476, Blast_Score=228, Evalue=1e-59,
Organism=Drosophila melanogaster, GI24655570, Length=454, Percent_Identity=31.2775330396476, Blast_Score=228, Evalue=1e-59,
Organism=Drosophila melanogaster, GI24655574, Length=454, Percent_Identity=31.2775330396476, Blast_Score=228, Evalue=1e-59,
Organism=Drosophila melanogaster, GI24655565, Length=454, Percent_Identity=31.2775330396476, Blast_Score=228, Evalue=1e-59,
Organism=Drosophila melanogaster, GI24654573, Length=437, Percent_Identity=32.4942791762014, Blast_Score=224, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24656367, Length=504, Percent_Identity=27.5793650793651, Blast_Score=176, Evalue=5e-44,
Organism=Drosophila melanogaster, GI21357867, Length=521, Percent_Identity=26.4875239923225, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI19922058, Length=485, Percent_Identity=25.7731958762887, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24652871, Length=452, Percent_Identity=26.3274336283186, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24656372, Length=352, Percent_Identity=28.6931818181818, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI45552909, Length=262, Percent_Identity=27.8625954198473, Blast_Score=85, Evalue=9e-17,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR005999 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.30 [H]

Molecular weight: Translated: 51599; Mature: 51599

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAILAIDQGTTNSKAVLVSEKGEIVGRGSAPVGISYPKPGWVEQDPRRLYASVCEAIDA
CCEEEEECCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
CLRASPALTIEAVAISNQRESVTAWDAETGEALGPLVSWQCRRTAPDCERLIAKGHLDRV
HHHCCCCEEEEEEEECCCCCCEEECCCCCCHHHHHHHCCHHCCCCHHHHHHHHHCCHHHH
QAVTGLPLDPMFPGSKFRWLLDRVPAGRSVRLGTVDSWLVHCLTGGRRHVCDASNAARSQ
HHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEECCHHHHHHHHHCCCCCEECCCCHHHHHH
LFDLREQRWSEELGEIFGVDIALLPEVLDSSADFGRTQGLPGVADGTPIMAAIGDSHAAL
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEE
FGHGAFTPGDGKVTFGTGSSVMTTLAQYIAPRNGVTTTVAWRIGGKPTFAFEGNILVCAA
EECCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEECCCEEEEEC
SLPWMADILGLADVAALVELAESAEPGGPGFVPAFVGLGAPYWNADARALFSQINFNTTR
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHCCCHHH
AQMARSVTDSIALQVHDVIAAMRAQSGGALGALYVDGGPSQNRFLMQCVSDLINHPVIQC
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEEE
EAPEASALGAAYLAGLSLGLWSDLDMVAGLPRKSQTIQPQPVDRAGLLDSWNDALARSTA
CCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHH
RETKAKGE
HHHHCCCC
>Mature Secondary Structure
MRAILAIDQGTTNSKAVLVSEKGEIVGRGSAPVGISYPKPGWVEQDPRRLYASVCEAIDA
CCEEEEECCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
CLRASPALTIEAVAISNQRESVTAWDAETGEALGPLVSWQCRRTAPDCERLIAKGHLDRV
HHHCCCCEEEEEEEECCCCCCEEECCCCCCHHHHHHHCCHHCCCCHHHHHHHHHCCHHHH
QAVTGLPLDPMFPGSKFRWLLDRVPAGRSVRLGTVDSWLVHCLTGGRRHVCDASNAARSQ
HHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEECCHHHHHHHHHCCCCCEECCCCHHHHHH
LFDLREQRWSEELGEIFGVDIALLPEVLDSSADFGRTQGLPGVADGTPIMAAIGDSHAAL
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEE
FGHGAFTPGDGKVTFGTGSSVMTTLAQYIAPRNGVTTTVAWRIGGKPTFAFEGNILVCAA
EECCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEECCCEEEEEC
SLPWMADILGLADVAALVELAESAEPGGPGFVPAFVGLGAPYWNADARALFSQINFNTTR
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHCCCHHH
AQMARSVTDSIALQVHDVIAAMRAQSGGALGALYVDGGPSQNRFLMQCVSDLINHPVIQC
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEEE
EAPEASALGAAYLAGLSLGLWSDLDMVAGLPRKSQTIQPQPVDRAGLLDSWNDALARSTA
CCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHH
RETKAKGE
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]