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The map label for this gene is fecC [C]

Identifier: 209549621

GI number: 209549621

Start: 2089616

End: 2090686

Strand: Direct

Name: fecC [C]

Synonym: Rleg2_2028

Alternate gene names: 209549621

Gene position: 2089616-2090686 (Clockwise)

Preceding gene: 209549620

Following gene: 209549622

Centisome position: 46.05

GC content: 65.36

Gene sequence:

>1071_bases
ATGGCCGAGATCGCCGCCATATCGATCGAAGCCGAAGCCGGGAGGGAGCGCTACCGCGCGCTCGCCCGGCGCAAGCTGTT
GATCCTCGCCGCCATGACGGCAGCGCTCTGTCTGTCATTTGCCGTCGATCTCGCCTGGGGCCCGGCCCGCTACAGCCTCA
GTGAGGTCGTGGCCGCCCTCCTCGACCCCTCCTCCGTTTCGGATCAGGTCCGCGCCGTCGTCTGGAACATCCGCATGCCG
GTCGCCGTCATGGCGATCGTCGTCGGCGCCTCGCTCTCCGTTGCCGGCGCGCAGATGCAGACCATCCTCGCCAATCCGCT
CGCCAGCCCTTTCACGCTTGGCATTTCGGCGGCGGCAAGCTTCGGCGCGGCTCTGGCGATCGTCACCAGCGTTCCGCTTC
TGCCTGTGGCCGCCGGTCTGCTGGTGCCAGTCAACGCCTTCGTGATGGCGCTGATTGCCACGCTCTTCATCCATTTCGTC
TCGCAGGCCCGCGGCGTCTGGGTGCAGACCGTGGTGCTGCTCGGCATCGCCCTGGTCTTCACCTTCAATGCGGCCCTCGC
CTTCCTGCAATATCTCGCCTCCGAACAGGCGCTTTCGGCGGTCGTCTTCTGGACGATGGGCAGCCTGACCAAGGCGACAT
GGCCGAAAATCTGGGTGACGCTCGCCGTCTTGCTGAGTGCCCTTCCGCTCTTTGCCCGCAATGCCTGGGCGCTGACCGCC
ATCCGCCTCGGCGAGGACAAGGCCGCGAGCTTCGGCGTCAATGTCCGCCGCATCCGGCTGGAAACCATGCTGGTTGTCTC
GCTGCTTGCCGCAGTCCCCGTCAGCTTCGTCGGCACCATCGGTTTCGTCGGCCTGGTCGGCCCGCATATCGCCCGAATGA
TTCTCGGCGAGGATCAGCGCTTCTTCTTGCCGGGCTCGATTCTGTCGGGCGCGCTATTGCTGTCGCTGACCTCGATCGTC
TCGAAGTCGATCATCCCCGGCGTCGTCTTCCCGATCGGCATCATCACCGCACTGGTCGGCGTGCCCTTCTTCTTCTCGCT
CATCCTCTCGAACAGGAGCCGGTCATGGTAG

Upstream 100 bases:

>100_bases
CGATCCGGATGCCACCTTCAAGGAATTCCACGAAAAATTCCTGCCGGTCGCCTATCAGCCGGGCTACTGGGTCGACGCCA
AGGCAGCTGAGTAAAACAGG

Downstream 100 bases:

>100_bases
CGCTTCAGTTGCAATCGGTCGGCGCCTATCACGGCCGCAAGCTCTTCGTCGAGAACGTGACGACACCGGTCATGAAATCC
GGCGAGATCGTCGCGGTCAT

Product: transporter permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MAEIAAISIEAEAGRERYRALARRKLLILAAMTAALCLSFAVDLAWGPARYSLSEVVAALLDPSSVSDQVRAVVWNIRMP
VAVMAIVVGASLSVAGAQMQTILANPLASPFTLGISAAASFGAALAIVTSVPLLPVAAGLLVPVNAFVMALIATLFIHFV
SQARGVWVQTVVLLGIALVFTFNAALAFLQYLASEQALSAVVFWTMGSLTKATWPKIWVTLAVLLSALPLFARNAWALTA
IRLGEDKAASFGVNVRRIRLETMLVVSLLAAVPVSFVGTIGFVGLVGPHIARMILGEDQRFFLPGSILSGALLLSLTSIV
SKSIIPGVVFPIGIITALVGVPFFFSLILSNRSRSW

Sequences:

>Translated_356_residues
MAEIAAISIEAEAGRERYRALARRKLLILAAMTAALCLSFAVDLAWGPARYSLSEVVAALLDPSSVSDQVRAVVWNIRMP
VAVMAIVVGASLSVAGAQMQTILANPLASPFTLGISAAASFGAALAIVTSVPLLPVAAGLLVPVNAFVMALIATLFIHFV
SQARGVWVQTVVLLGIALVFTFNAALAFLQYLASEQALSAVVFWTMGSLTKATWPKIWVTLAVLLSALPLFARNAWALTA
IRLGEDKAASFGVNVRRIRLETMLVVSLLAAVPVSFVGTIGFVGLVGPHIARMILGEDQRFFLPGSILSGALLLSLTSIV
SKSIIPGVVFPIGIITALVGVPFFFSLILSNRSRSW
>Mature_355_residues
AEIAAISIEAEAGRERYRALARRKLLILAAMTAALCLSFAVDLAWGPARYSLSEVVAALLDPSSVSDQVRAVVWNIRMPV
AVMAIVVGASLSVAGAQMQTILANPLASPFTLGISAAASFGAALAIVTSVPLLPVAAGLLVPVNAFVMALIATLFIHFVS
QARGVWVQTVVLLGIALVFTFNAALAFLQYLASEQALSAVVFWTMGSLTKATWPKIWVTLAVLLSALPLFARNAWALTAI
RLGEDKAASFGVNVRRIRLETMLVVSLLAAVPVSFVGTIGFVGLVGPHIARMILGEDQRFFLPGSILSGALLLSLTSIVS
KSIIPGVVFPIGIITALVGVPFFFSLILSNRSRSW

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790741, Length=292, Percent_Identity=33.5616438356164, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790740, Length=297, Percent_Identity=31.6498316498317, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1788004, Length=279, Percent_Identity=32.6164874551971, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1786347, Length=363, Percent_Identity=30.8539944903581, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1786805, Length=278, Percent_Identity=31.294964028777, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1786804, Length=339, Percent_Identity=30.9734513274336, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37567; Mature: 37436

Theoretical pI: Translated: 11.16; Mature: 11.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEIAAISIEAEAGRERYRALARRKLLILAAMTAALCLSFAVDLAWGPARYSLSEVVAAL
CCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LDPSSVSDQVRAVVWNIRMPVAVMAIVVGASLSVAGAQMQTILANPLASPFTLGISAAAS
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
FGAALAIVTSVPLLPVAAGLLVPVNAFVMALIATLFIHFVSQARGVWVQTVVLLGIALVF
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
TFNAALAFLQYLASEQALSAVVFWTMGSLTKATWPKIWVTLAVLLSALPLFARNAWALTA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEE
IRLGEDKAASFGVNVRRIRLETMLVVSLLAAVPVSFVGTIGFVGLVGPHIARMILGEDQR
EEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FFLPGSILSGALLLSLTSIVSKSIIPGVVFPIGIITALVGVPFFFSLILSNRSRSW
EEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AEIAAISIEAEAGRERYRALARRKLLILAAMTAALCLSFAVDLAWGPARYSLSEVVAAL
CCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LDPSSVSDQVRAVVWNIRMPVAVMAIVVGASLSVAGAQMQTILANPLASPFTLGISAAAS
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
FGAALAIVTSVPLLPVAAGLLVPVNAFVMALIATLFIHFVSQARGVWVQTVVLLGIALVF
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
TFNAALAFLQYLASEQALSAVVFWTMGSLTKATWPKIWVTLAVLLSALPLFARNAWALTA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEE
IRLGEDKAASFGVNVRRIRLETMLVVSLLAAVPVSFVGTIGFVGLVGPHIARMILGEDQR
EEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FFLPGSILSGALLLSLTSIVSKSIIPGVVFPIGIITALVGVPFFFSLILSNRSRSW
EEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]