Click here to switch to the map view.

The map label for this gene is gst [C]

Identifier: 209549549

GI number: 209549549

Start: 1999463

End: 2000089

Strand: Direct

Name: gst [C]

Synonym: Rleg2_1955

Alternate gene names: 209549549

Gene position: 1999463-2000089 (Clockwise)

Preceding gene: 209549548

Following gene: 209549553

Centisome position: 44.06

GC content: 62.36

Gene sequence:

>627_bases
ATGACCGAAGAATTGGTATTCTACACGAACCCGATGTCACGCGGCCGCACCGCACGCTGGATGCTGGAGGAAATCGGTCA
GCCCTATCGCACAGAGCTTCTGACCTTCGGCGAAACCATGAAGGCACCGGAATATCTGCGGGTCAACCCGATGGGCAAGG
TGCCGGCGATCCGCCATGGCAACACCGTCGTCACCGAATGCGCGGCGATCTGCGCCTATCTCGCCGAAACCTTCCCGGAA
AAGGGGCTGGCCCCCAAACCGCAGGAGCGCGCCGCCTATTACCGCTGGATGTTCTTTGCCGCCGGTCCGCTGGAATCGGC
GGTGACGATGAAGGCGCTCGGCTTCGACATTCCGACGGAGAAGTTGCGCATGGCCGGCTGCGGCGGCTTCGGCGACGTTA
TGAACACGCTTGAAATGGCCGTTTCCGGCTCGACTTATGTTGCCGGCGAACGCTTCACCGCCGCCGACGTCTATGTCGGC
TCGCATGTCGGCTGGGGCCTCGGCTTCGGCAGCATCGAAAAGCGCCAGGCCTTCGTCGATTATTTCGGCCGCATCAGCGA
ACGTGAGGCCTATAAGCGCGCCAATGCGCTGGATGACGAGGCCGGCAAGACGATGCAGGCGGCCTGA

Upstream 100 bases:

>100_bases
CGGGCTTCATCCAGTACCGCAAGGCTCTCTAAAGATCGGGGGTTGCACAAACACCTTGCCGCGCTATTGATTCCGAGCGA
CGCAACAGGAGGAGGATGTC

Downstream 100 bases:

>100_bases
TCGCCGCCGGCGCGGCTCCAATGTGGCCGCGCCGGGATGTCAGCCCTCAGGCGAGCGGCATATGGATATCCGTCATCAAC
TCGGTCGGCGGCACGTCGCG

Product: glutathione S-transferase domain

Products: HX; R-S-Glutathione; S-(2,4-dinitrophenyl)glutathione [C]

Alternate protein names: Glutathione S-Transferase Domain-Containing Protein; Glutathione S-Transferase Domain Protein; Glutathione S-Transferase-Like; Glutathione S-Transferase-Like Protein; Glutathione S-Transferase Domain; Glutathione Transferase; Glutathione S-Transferase Family Protein; Glutathione S-Transferase N-Terminal Domain Protein; Glutathione S-Transferase Protein; Glutathione S-Transferase III; Glutathione S-Transferase N-Terminal Domain; Glutathione S-Transferase N-Terminal Domain-Containing; Transcriptional Regulator; Glutathione S Transferase; Gst Protein; Glutatione S-Transferase; GSH-Dependent Dehydroascorbate Reductase

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MTEELVFYTNPMSRGRTARWMLEEIGQPYRTELLTFGETMKAPEYLRVNPMGKVPAIRHGNTVVTECAAICAYLAETFPE
KGLAPKPQERAAYYRWMFFAAGPLESAVTMKALGFDIPTEKLRMAGCGGFGDVMNTLEMAVSGSTYVAGERFTAADVYVG
SHVGWGLGFGSIEKRQAFVDYFGRISEREAYKRANALDDEAGKTMQAA

Sequences:

>Translated_208_residues
MTEELVFYTNPMSRGRTARWMLEEIGQPYRTELLTFGETMKAPEYLRVNPMGKVPAIRHGNTVVTECAAICAYLAETFPE
KGLAPKPQERAAYYRWMFFAAGPLESAVTMKALGFDIPTEKLRMAGCGGFGDVMNTLEMAVSGSTYVAGERFTAADVYVG
SHVGWGLGFGSIEKRQAFVDYFGRISEREAYKRANALDDEAGKTMQAA
>Mature_207_residues
TEELVFYTNPMSRGRTARWMLEEIGQPYRTELLTFGETMKAPEYLRVNPMGKVPAIRHGNTVVTECAAICAYLAETFPEK
GLAPKPQERAAYYRWMFFAAGPLESAVTMKALGFDIPTEKLRMAGCGGFGDVMNTLEMAVSGSTYVAGERFTAADVYVGS
HVGWGLGFGSIEKRQAFVDYFGRISEREAYKRANALDDEAGKTMQAA

Specific function: Conjugation Of Reduced Glutathione To A Wide Number Of Exogenous And Endogenous Hydrophobic Electrophiles. [C]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.5.1.18 [C]

Molecular weight: Translated: 23004; Mature: 22872

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEELVFYTNPMSRGRTARWMLEEIGQPYRTELLTFGETMKAPEYLRVNPMGKVPAIRHG
CCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCEECC
NTVVTECAAICAYLAETFPEKGLAPKPQERAAYYRWMFFAAGPLESAVTMKALGFDIPTE
CHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHH
KLRMAGCGGFGDVMNTLEMAVSGSTYVAGERFTAADVYVGSHVGWGLGFGSIEKRQAFVD
HHHHHCCCCHHHHHHHHHHHHCCCEEECCCCEEEHHEEECCCCCCCCCCCCHHHHHHHHH
YFGRISEREAYKRANALDDEAGKTMQAA
HHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TEELVFYTNPMSRGRTARWMLEEIGQPYRTELLTFGETMKAPEYLRVNPMGKVPAIRHG
CCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCEECC
NTVVTECAAICAYLAETFPEKGLAPKPQERAAYYRWMFFAAGPLESAVTMKALGFDIPTE
CHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHH
KLRMAGCGGFGDVMNTLEMAVSGSTYVAGERFTAADVYVGSHVGWGLGFGSIEKRQAFVD
HHHHHCCCCHHHHHHHHHHHHCCCEEECCCCEEEHHEEECCCCCCCCCCCCHHHHHHHHH
YFGRISEREAYKRANALDDEAGKTMQAA
HHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; Glutathione; 1-chloro-2,4-dinitrobenzene; reduced glutathione [C]

Specific reaction: RX + Glutathione = HX + R-S-Glutathione 1-chloro-2,4-dinitrobenzene + reduced glutathione = S-(2,4-dinitrophenyl)glutathione [C]

General reaction: Aryl group transfer [C]

Inhibitor: Cd2+; CibacronBlue; Co2+; Cu2+; Hematin; Hg2+; Ni2+; Sulfophthaleins; Tributyl tinacetate; Triethyl tinbromide; Zn2+ [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA