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The map label for this gene is purQ [H]

Identifier: 209549523

GI number: 209549523

Start: 1974312

End: 1974983

Strand: Direct

Name: purQ [H]

Synonym: Rleg2_1929

Alternate gene names: 209549523

Gene position: 1974312-1974983 (Clockwise)

Preceding gene: 209549522

Following gene: 209549524

Centisome position: 43.51

GC content: 61.9

Gene sequence:

>672_bases
ATGAAATCAGCCGTCGTTCAACTTCCGGGCCTCAACCGCGACCGCGATATGATCGCCGCCCTGACGAAGATTTCCGGCAA
GCCGCCGGTGACGATCTGGCAGACGGAAACCGAGATCCCCGATGTCGACCTGATCGTCATCCCCGGCGGCTTCTCCTATG
GCGATTACCTGCGCTGCGGCGCGATCGCCGCCCGCATGCCGGTCATGCAGGCGATCATCGACAAGGCTGAAAAAGGCGTG
AAGGTGCTCGGCGTCTGCAACGGCTTCCAGATCCTCGTCGAGGCCGGCCTGCTGCCTGGCGCGCTGATGCGCAATGCTTC
GCTGAAATTCGTCTGCCGCGAAATCAAACTCGAAGTCGTCAATGCCGAGACGGATTTCACACGCGCCTACGCGCAGGGCC
AGATCATCCGCAGCCCGGTTGCCCATCACGACGGCAATTATTTCGCCGATGAAGCAACGCTGGCGGCAATCGAAGGCAAT
GGCCAGGTGGTGTTCCGCTATGCCGAGGGCACCAACCCGAACGGCTCGGTCAACGACATCGCCGCTGTTATGAATGAAAA
GGGCAACGTGCTCGGCATGATGCCGCATCCCGAAAACCTGATCGAAGCCGCCCATGGCGGCTCGGACGGCCGCGGCCTGT
TCGCCTCGGCGCTCGATGTCATTGCCGCCTGA

Upstream 100 bases:

>100_bases
GCATGTTTTCAGAAGGCCATTCTTTCTTTGTCTCCGACAATGGAGTATGGCTCGCCGAAAGCGTTCCAGTTCAATATCTT
TCGCCAGACGCGGGGACCCC

Downstream 100 bases:

>100_bases
AATCCTCTCATCCGGATCTGGAGCAAGATCGATGCGCCCTCGCCTTTCCCTAGCAAATGCCGCCCTGCTTGCCGCTCTCG
CAGCCATGGTCGCGGCCTGC

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MKSAVVQLPGLNRDRDMIAALTKISGKPPVTIWQTETEIPDVDLIVIPGGFSYGDYLRCGAIAARMPVMQAIIDKAEKGV
KVLGVCNGFQILVEAGLLPGALMRNASLKFVCREIKLEVVNAETDFTRAYAQGQIIRSPVAHHDGNYFADEATLAAIEGN
GQVVFRYAEGTNPNGSVNDIAAVMNEKGNVLGMMPHPENLIEAAHGGSDGRGLFASALDVIAA

Sequences:

>Translated_223_residues
MKSAVVQLPGLNRDRDMIAALTKISGKPPVTIWQTETEIPDVDLIVIPGGFSYGDYLRCGAIAARMPVMQAIIDKAEKGV
KVLGVCNGFQILVEAGLLPGALMRNASLKFVCREIKLEVVNAETDFTRAYAQGQIIRSPVAHHDGNYFADEATLAAIEGN
GQVVFRYAEGTNPNGSVNDIAAVMNEKGNVLGMMPHPENLIEAAHGGSDGRGLFASALDVIAA
>Mature_223_residues
MKSAVVQLPGLNRDRDMIAALTKISGKPPVTIWQTETEIPDVDLIVIPGGFSYGDYLRCGAIAARMPVMQAIIDKAEKGV
KVLGVCNGFQILVEAGLLPGALMRNASLKFVCREIKLEVVNAETDFTRAYAQGQIIRSPVAHHDGNYFADEATLAAIEGN
GQVVFRYAEGTNPNGSVNDIAAVMNEKGNVLGMMPHPENLIEAAHGGSDGRGLFASALDVIAA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=227, Percent_Identity=31.2775330396476, Blast_Score=79, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24582111, Length=231, Percent_Identity=26.4069264069264, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24582109, Length=231, Percent_Identity=26.4069264069264, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17137292, Length=231, Percent_Identity=26.4069264069264, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 23706; Mature: 23706

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSAVVQLPGLNRDRDMIAALTKISGKPPVTIWQTETEIPDVDLIVIPGGFSYGDYLRCG
CCCCEEECCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCHHHHH
AIAARMPVMQAIIDKAEKGVKVLGVCNGFQILVEAGLLPGALMRNASLKFVCREIKLEVV
HHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEHHHCCCCHHHHHCCCHHHEEEEEEEEEE
NAETDFTRAYAQGQIIRSPVAHHDGNYFADEATLAAIEGNGQVVFRYAEGTNPNGSVNDI
ECCCHHHHHHHCCCHHHCCCHHCCCCEEECCEEEEEEECCCEEEEEEECCCCCCCCHHHH
AAVMNEKGNVLGMMPHPENLIEAAHGGSDGRGLFASALDVIAA
HHHHCCCCCEEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKSAVVQLPGLNRDRDMIAALTKISGKPPVTIWQTETEIPDVDLIVIPGGFSYGDYLRCG
CCCCEEECCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCHHHHH
AIAARMPVMQAIIDKAEKGVKVLGVCNGFQILVEAGLLPGALMRNASLKFVCREIKLEVV
HHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEHHHCCCCHHHHHCCCHHHEEEEEEEEEE
NAETDFTRAYAQGQIIRSPVAHHDGNYFADEATLAAIEGNGQVVFRYAEGTNPNGSVNDI
ECCCHHHHHHHCCCHHHCCCHHCCCCEEECCEEEEEEECCCEEEEEEECCCCCCCCHHHH
AAVMNEKGNVLGMMPHPENLIEAAHGGSDGRGLFASALDVIAA
HHHHCCCCCEEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA