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The map label for this gene is kptA

Identifier: 209549522

GI number: 209549522

Start: 1973761

End: 1974315

Strand: Direct

Name: kptA

Synonym: Rleg2_1928

Alternate gene names: 209549522

Gene position: 1973761-1974315 (Clockwise)

Preceding gene: 209549521

Following gene: 209549523

Centisome position: 43.49

GC content: 54.77

Gene sequence:

>555_bases
ATGACGCAGGCAAAGCTGGAGACGGAAGTCTCGAAATATATGAGCTATGTTTTGCGTCATGCGCCTGAAGCCGCCGGTTT
GACGCTAGATGCCGAGGGCTGGGTGTCGTTCGATGAGCTCGAAAAGGCGCTGACGTCGAAATACGACGTTTCCCGCGCCG
ACATTATCGAGATCGTCGAAAACAATCCGAAGAATCGCTTCACCATTGTCGACAACAGAATTCGCGCCAATCAGGGTCAT
AGTGTCGACGTCGATCTCGCATTGACCCCGGTGGAACCGCCAGCGGCTCTCTATCACGGCACGTCTTCGGCCAACTGGCA
TTCGATCGAGCGCGAAGGCTTGAAGAAGATGCAGCGTCATCACGTTCATCTCTCGGCGGATGTCGAAACCGCGAAAATCG
TCGCAACGCGCCGCAAGGGTGAATATCTCATCCTGCGTGTCGATGCGGCCCGCATGTTTTCAGAAGGCCATTCTTTCTTT
GTCTCCGACAATGGAGTATGGCTCGCCGAAAGCGTTCCAGTTCAATATCTTTCGCCAGACGCGGGGACCCCATGA

Upstream 100 bases:

>100_bases
GCGAGAAGCTCCTCGCCAACACGGTCATCGAGAACTACGCGATCGCGATCGACTGACGATCACCGACCCGTCGTCCGGCG
GACTTTTAGGATTTGGCGTC

Downstream 100 bases:

>100_bases
AATCAGCCGTCGTTCAACTTCCGGGCCTCAACCGCGACCGCGATATGATCGCCGCCCTGACGAAGATTTCCGGCAAGCCG
CCGGTGACGATCTGGCAGAC

Product: RNA 2'-phosphotransferase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MTQAKLETEVSKYMSYVLRHAPEAAGLTLDAEGWVSFDELEKALTSKYDVSRADIIEIVENNPKNRFTIVDNRIRANQGH
SVDVDLALTPVEPPAALYHGTSSANWHSIEREGLKKMQRHHVHLSADVETAKIVATRRKGEYLILRVDAARMFSEGHSFF
VSDNGVWLAESVPVQYLSPDAGTP

Sequences:

>Translated_184_residues
MTQAKLETEVSKYMSYVLRHAPEAAGLTLDAEGWVSFDELEKALTSKYDVSRADIIEIVENNPKNRFTIVDNRIRANQGH
SVDVDLALTPVEPPAALYHGTSSANWHSIEREGLKKMQRHHVHLSADVETAKIVATRRKGEYLILRVDAARMFSEGHSFF
VSDNGVWLAESVPVQYLSPDAGTP
>Mature_183_residues
TQAKLETEVSKYMSYVLRHAPEAAGLTLDAEGWVSFDELEKALTSKYDVSRADIIEIVENNPKNRFTIVDNRIRANQGHS
VDVDLALTPVEPPAALYHGTSSANWHSIEREGLKKMQRHHVHLSADVETAKIVATRRKGEYLILRVDAARMFSEGHSFFV
SDNGVWLAESVPVQYLSPDAGTP

Specific function: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP- ribosy

COG id: COG1859

COG function: function code J; RNA:NAD 2'-phosphotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kptA/TPT1 family

Homologues:

Organism=Homo sapiens, GI238550157, Length=185, Percent_Identity=33.5135135135135, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI238550153, Length=185, Percent_Identity=33.5135135135135, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI238550149, Length=187, Percent_Identity=33.1550802139037, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI238550169, Length=186, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=1e-16,
Organism=Homo sapiens, GI238550165, Length=133, Percent_Identity=36.8421052631579, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI87082424, Length=173, Percent_Identity=42.7745664739884, Blast_Score=124, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6324470, Length=196, Percent_Identity=31.6326530612245, Blast_Score=76, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28575019, Length=185, Percent_Identity=28.6486486486486, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KPTA_RHILW (B5ZQT5)

Other databases:

- EMBL:   CP001191
- RefSeq:   YP_002281439.1
- ProteinModelPortal:   B5ZQT5
- SMR:   B5ZQT5
- GeneID:   6980667
- GenomeReviews:   CP001191_GR
- KEGG:   rlt:Rleg2_1928
- HOGENOM:   HBG332834
- OMA:   CEIAVFI
- ProtClustDB:   PRK00819
- HAMAP:   MF_00299
- InterPro:   IPR022928
- InterPro:   IPR002745

Pfam domain/function: PF01885 PTS_2-RNA

EC number: 2.7.-.- [C]

Molecular weight: Translated: 20545; Mature: 20414

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQAKLETEVSKYMSYVLRHAPEAAGLTLDAEGWVSFDELEKALTSKYDVSRADIIEIVE
CCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHH
NNPKNRFTIVDNRIRANQGHSVDVDLALTPVEPPAALYHGTSSANWHSIEREGLKKMQRH
CCCCCEEEEEECEEECCCCCEEEEEEEEECCCCCHHEEECCCCCCCHHHHHHHHHHHHHH
HVHLSADVETAKIVATRRKGEYLILRVDAARMFSEGHSFFVSDNGVWLAESVPVQYLSPD
CEEEECCCCEEEEEEEECCCCEEEEEECHHHHHHCCCEEEEECCCEEEECCCCEEEECCC
AGTP
CCCC
>Mature Secondary Structure 
TQAKLETEVSKYMSYVLRHAPEAAGLTLDAEGWVSFDELEKALTSKYDVSRADIIEIVE
CCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHH
NNPKNRFTIVDNRIRANQGHSVDVDLALTPVEPPAALYHGTSSANWHSIEREGLKKMQRH
CCCCCEEEEEECEEECCCCCEEEEEEEEECCCCCHHEEECCCCCCCHHHHHHHHHHHHHH
HVHLSADVETAKIVATRRKGEYLILRVDAARMFSEGHSFFVSDNGVWLAESVPVQYLSPD
CEEEECCCCEEEEEEEECCCCEEEEEECHHHHHHCCCEEEEECCCEEEECCCCEEEECCC
AGTP
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA