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The map label for this gene is csd [H]

Identifier: 209549490

GI number: 209549490

Start: 1939910

End: 1941151

Strand: Reverse

Name: csd [H]

Synonym: Rleg2_1896

Alternate gene names: 209549490

Gene position: 1941151-1939910 (Counterclockwise)

Preceding gene: 209549491

Following gene: 209549489

Centisome position: 42.78

GC content: 61.92

Gene sequence:

>1242_bases
ATGGACAAGATCGTGCCGGCCACGCCATACGATGTCGAAGCCATCCGCCGGGATTTTCCGATCCTGGCGGAGAAGGTGCA
CGGCAAGCCGCTGGTCTATCTCGACAACGGCGCCTCGGCACAGAAGCCGCAGGTGGTGATCGACGCCATCTCGCACGCCT
ACGCCCATGAATATGCCAATGTGCATCGCGGCCTGCACTATCTCTCCAATGCTGCGACGGATGCCTATGAGGCGGCGCGC
GAGAAGGTGCGCCGTTTCCTCAACGCTCCTTCGGTCAACGACATCGTCTTCACCAAGAATTCAACGGAAGCGATCAACAC
CGTCGCCTATGGCTGGGGCATGCCCGAGATCGGCGAGGGCGACGAGATCGTCCTGACGATCATGGAGCATCATTCCAACA
TCGTGCCCTGGCACTTCATCCGTGAGCGGCAGGGTGCCAAACTCGTCTGGGTGCCGGTCGACGACGAGGGCGCCTTCCAT
ATCGAGGATTTCGAGAAGAGCCTGACGGAGCGCACCAAGCTCGTCGCCATCACCCATATGTCGAATGCGCTCGGCACGAT
CGTTCCCGTCAAGGAAGTTTGCCGGATTGCGCATGAGCGCGGCATCCCGGTGCTGATCGACGGCAGCCAGGGCGCCGTGC
ATCTGCCTGTCGACGTGCAGGATATCGATTGCGACTGGTATGTGATGACCGGCCACAAGCTCTACGGCCCGTCGGGCATC
GGCGTGCTTTACGGCAAGAAGGAGCGGCTTTCCCAAATGCGCCCCTTCCAGGGCGGCGGCGAGATGATTTTCGAAGTTGC
CGAGGACGCGGTCACCTACAATGATCCGCCGCACCGCTTCGAGGCCGGCACGCCGCCGATCGTCCAGGCGATCGGGCTCG
GCTACGCGCTCGACTATATGGAGAAGGTCGGCCGCGAGGCGATCGCCCGGCATGAGGCCGATCTTGCCGCTTACGCTGTG
GAACGGCTGAAAACGGTCAATTCGCTGCGCGTCTTCGGAACGGCGCCCGACAAGGGCAGCATCTTTTCCTTCGAGCTTGC
CGGCATCCATGCCCATGACGTCTCGATGGTGATCGACCGGCAGGGCGTTGCGGTGCGAGCCGGCACGCATTGCGCCATGC
CGCTCTTGAAACGCTTCGGCGTCACCTCCACATGCCGTGCATCCTTCGGCATGTACAATACCCGCGCCGAGGTCGATGCC
CTGGCCGATGCGCTTGAATATGCGCGCAAGTTCTTTGCTTGA

Upstream 100 bases:

>100_bases
CGCCGAGATCGTCGAGGAACTGGAAGACGAGGCCCTGGTCGAAGCGCTGGAAGGCGTGATTTCGGCCTGGCTCGAAAAGC
ACGCCTGATCGGATATAGCA

Downstream 100 bases:

>100_bases
GGAGTGTCCGTGATGAGCCTGGACGAAAGCGAACAGAAGATCGACGTGCGCGAAGGCATCGTGCATTCCAGCATTCCGGC
CGATGAGCTGGCGCGGCTCA

Product: SufS subfamily cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MDKIVPATPYDVEAIRRDFPILAEKVHGKPLVYLDNGASAQKPQVVIDAISHAYAHEYANVHRGLHYLSNAATDAYEAAR
EKVRRFLNAPSVNDIVFTKNSTEAINTVAYGWGMPEIGEGDEIVLTIMEHHSNIVPWHFIRERQGAKLVWVPVDDEGAFH
IEDFEKSLTERTKLVAITHMSNALGTIVPVKEVCRIAHERGIPVLIDGSQGAVHLPVDVQDIDCDWYVMTGHKLYGPSGI
GVLYGKKERLSQMRPFQGGGEMIFEVAEDAVTYNDPPHRFEAGTPPIVQAIGLGYALDYMEKVGREAIARHEADLAAYAV
ERLKTVNSLRVFGTAPDKGSIFSFELAGIHAHDVSMVIDRQGVAVRAGTHCAMPLLKRFGVTSTCRASFGMYNTRAEVDA
LADALEYARKFFA

Sequences:

>Translated_413_residues
MDKIVPATPYDVEAIRRDFPILAEKVHGKPLVYLDNGASAQKPQVVIDAISHAYAHEYANVHRGLHYLSNAATDAYEAAR
EKVRRFLNAPSVNDIVFTKNSTEAINTVAYGWGMPEIGEGDEIVLTIMEHHSNIVPWHFIRERQGAKLVWVPVDDEGAFH
IEDFEKSLTERTKLVAITHMSNALGTIVPVKEVCRIAHERGIPVLIDGSQGAVHLPVDVQDIDCDWYVMTGHKLYGPSGI
GVLYGKKERLSQMRPFQGGGEMIFEVAEDAVTYNDPPHRFEAGTPPIVQAIGLGYALDYMEKVGREAIARHEADLAAYAV
ERLKTVNSLRVFGTAPDKGSIFSFELAGIHAHDVSMVIDRQGVAVRAGTHCAMPLLKRFGVTSTCRASFGMYNTRAEVDA
LADALEYARKFFA
>Mature_413_residues
MDKIVPATPYDVEAIRRDFPILAEKVHGKPLVYLDNGASAQKPQVVIDAISHAYAHEYANVHRGLHYLSNAATDAYEAAR
EKVRRFLNAPSVNDIVFTKNSTEAINTVAYGWGMPEIGEGDEIVLTIMEHHSNIVPWHFIRERQGAKLVWVPVDDEGAFH
IEDFEKSLTERTKLVAITHMSNALGTIVPVKEVCRIAHERGIPVLIDGSQGAVHLPVDVQDIDCDWYVMTGHKLYGPSGI
GVLYGKKERLSQMRPFQGGGEMIFEVAEDAVTYNDPPHRFEAGTPPIVQAIGLGYALDYMEKVGREAIARHEADLAAYAV
ERLKTVNSLRVFGTAPDKGSIFSFELAGIHAHDVSMVIDRQGVAVRAGTHCAMPLLKRFGVTSTCRASFGMYNTRAEVDA
LADALEYARKFFA

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=407, Percent_Identity=23.8329238329238, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI156713448, Length=423, Percent_Identity=26.241134751773, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1787970, Length=404, Percent_Identity=46.039603960396, Blast_Score=382, Evalue=1e-107,
Organism=Escherichia coli, GI1789175, Length=406, Percent_Identity=40.1477832512315, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI48994898, Length=368, Percent_Identity=23.3695652173913, Blast_Score=98, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI25143064, Length=243, Percent_Identity=29.2181069958848, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI193211090, Length=374, Percent_Identity=24.8663101604278, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17533177, Length=332, Percent_Identity=24.0963855421687, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319831, Length=395, Percent_Identity=24.5569620253165, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI20129463, Length=404, Percent_Identity=25.990099009901, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 45626; Mature: 45626

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIVPATPYDVEAIRRDFPILAEKVHGKPLVYLDNGASAQKPQVVIDAISHAYAHEYAN
CCCCCCCCCCCHHHHHCCCCHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
VHRGLHYLSNAATDAYEAAREKVRRFLNAPSVNDIVFTKNSTEAINTVAYGWGMPEIGEG
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHCCCCCCCCCCC
DEIVLTIMEHHSNIVPWHFIRERQGAKLVWVPVDDEGAFHIEDFEKSLTERTKLVAITHM
CEEEEEEEHHCCCCCCHHHHHHCCCCEEEEEEECCCCCEEHHHHHHHHHHHHEEEEEEEC
SNALGTIVPVKEVCRIAHERGIPVLIDGSQGAVHLPVDVQDIDCDWYVMTGHKLYGPSGI
CCHHHHHCCHHHHHHHHHHCCCEEEEECCCCCEECCEEEEECCCCEEEEECCEEECCCCC
GVLYGKKERLSQMRPFQGGGEMIFEVAEDAVTYNDPPHRFEAGTPPIVQAIGLGYALDYM
EEEECCHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
EKVGREAIARHEADLAAYAVERLKTVNSLRVFGTAPDKGSIFSFELAGIHAHDVSMVIDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCEEEEEEECEEECCEEEEEEC
QGVAVRAGTHCAMPLLKRFGVTSTCRASFGMYNTRAEVDALADALEYARKFFA
CCEEEECCCHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDKIVPATPYDVEAIRRDFPILAEKVHGKPLVYLDNGASAQKPQVVIDAISHAYAHEYAN
CCCCCCCCCCCHHHHHCCCCHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
VHRGLHYLSNAATDAYEAAREKVRRFLNAPSVNDIVFTKNSTEAINTVAYGWGMPEIGEG
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHCCCCCCCCCCC
DEIVLTIMEHHSNIVPWHFIRERQGAKLVWVPVDDEGAFHIEDFEKSLTERTKLVAITHM
CEEEEEEEHHCCCCCCHHHHHHCCCCEEEEEEECCCCCEEHHHHHHHHHHHHEEEEEEEC
SNALGTIVPVKEVCRIAHERGIPVLIDGSQGAVHLPVDVQDIDCDWYVMTGHKLYGPSGI
CCHHHHHCCHHHHHHHHHHCCCEEEEECCCCCEECCEEEEECCCCEEEEECCEEECCCCC
GVLYGKKERLSQMRPFQGGGEMIFEVAEDAVTYNDPPHRFEAGTPPIVQAIGLGYALDYM
EEEECCHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
EKVGREAIARHEADLAAYAVERLKTVNSLRVFGTAPDKGSIFSFELAGIHAHDVSMVIDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCEEEEEEECEEECCEEEEEEC
QGVAVRAGTHCAMPLLKRFGVTSTCRASFGMYNTRAEVDALADALEYARKFFA
CCEEEECCCHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]