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The map label for this gene is ompR [H]

Identifier: 209549359

GI number: 209549359

Start: 1805076

End: 1805816

Strand: Direct

Name: ompR [H]

Synonym: Rleg2_1763

Alternate gene names: 209549359

Gene position: 1805076-1805816 (Clockwise)

Preceding gene: 209549348

Following gene: 209549360

Centisome position: 39.78

GC content: 59.78

Gene sequence:

>741_bases
GTGCTGAATCAGAAGGTTAGAATTCTGATCGTCGAGGACGATCCTGATATGGCGGAGCTTATCTCCGATCTCGTCGAGGC
CGAGGGGTGGATACCGACCTGCGCGGGATCCGCCGAGGAGGCGACCGATATCCTGGCGCGAGAGCAGATGCATCTGGTGC
TTGTCGATCATAACCTGCCGCGTACATCCGGCCGAGCTTTCGCCCAAAAACTGCGGTCAGAGATCAATATCGGCATCGTC
ATGGTGACGGCAGCCGGCAGTGCTGCCGATCGCGTCCTCGGCCTTGAAACCGCTGCGGATGATTATGTCGTCAAGCCGTT
CGAACCGATCGAACTGACGGCCCGCATCAAAGCTGTCTTACGGCGAACCGTGCCGTCGCTGAAACAGGAAAAGGAGAGCG
AGCGGGAGCACGAACGTCCCTCTTTGCTGCTTGGCGACTGGGCAATCGATCTGATGGGCCGGCAAGCCGTCTGCCTCGCA
GATCGCAGCAAAACGCTGACAACGGCTGAGTTCGCCTTGCTTGAAATCCTTGCGCAGACCCCCAATCAGCCGGTGAGCCG
AGCGCAGATCCTCGATCGGCTTGGCTCGGAAAGTGATCGCTACATCGACCGCAACGTCGACGTCCTGGTTCTGCGGCTCC
GGCGGAAAATCGAACGCAATCCCGACCTTCCGCGCCATATCAAGACACGACGCGGAAAGGGCTATGTCCTGCACACTGGC
GACGGCGAGCCGTCAGCGTGA

Upstream 100 bases:

>100_bases
AACGACGTTACATTCATTACAAATGTGACAAACCTCATCATCAGCAAGTCTTTGAACATTGGCGGCGGCATGCCTATGAT
AGCGGGGGGAGGATCAAGCT

Downstream 100 bases:

>100_bases
TCAGCCGCTCCTTTCTGTCGTCGATTGCCTTTCGCTTGCCTTTCGCGATTGCCTTCATCTGCTTCCTGGTTTTCAGTCTT
TCAGCGATCGCGATCTACGG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MLNQKVRILIVEDDPDMAELISDLVEAEGWIPTCAGSAEEATDILAREQMHLVLVDHNLPRTSGRAFAQKLRSEINIGIV
MVTAAGSAADRVLGLETAADDYVVKPFEPIELTARIKAVLRRTVPSLKQEKESEREHERPSLLLGDWAIDLMGRQAVCLA
DRSKTLTTAEFALLEILAQTPNQPVSRAQILDRLGSESDRYIDRNVDVLVLRLRRKIERNPDLPRHIKTRRGKGYVLHTG
DGEPSA

Sequences:

>Translated_246_residues
MLNQKVRILIVEDDPDMAELISDLVEAEGWIPTCAGSAEEATDILAREQMHLVLVDHNLPRTSGRAFAQKLRSEINIGIV
MVTAAGSAADRVLGLETAADDYVVKPFEPIELTARIKAVLRRTVPSLKQEKESEREHERPSLLLGDWAIDLMGRQAVCLA
DRSKTLTTAEFALLEILAQTPNQPVSRAQILDRLGSESDRYIDRNVDVLVLRLRRKIERNPDLPRHIKTRRGKGYVLHTG
DGEPSA
>Mature_246_residues
MLNQKVRILIVEDDPDMAELISDLVEAEGWIPTCAGSAEEATDILAREQMHLVLVDHNLPRTSGRAFAQKLRSEINIGIV
MVTAAGSAADRVLGLETAADDYVVKPFEPIELTARIKAVLRRTVPSLKQEKESEREHERPSLLLGDWAIDLMGRQAVCLA
DRSKTLTTAEFALLEILAQTPNQPVSRAQILDRLGSESDRYIDRNVDVLVLRLRRKIERNPDLPRHIKTRRGKGYVLHTG
DGEPSA

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=237, Percent_Identity=35.8649789029536, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=34.051724137931, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=34.4978165938865, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1786599, Length=242, Percent_Identity=34.7107438016529, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=35.9307359307359, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786784, Length=240, Percent_Identity=31.25, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=30.7359307359307, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1790860, Length=236, Percent_Identity=30.0847457627119, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1790552, Length=233, Percent_Identity=30.9012875536481, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=31.6017316017316, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789402, Length=233, Percent_Identity=30.4721030042918, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=26.3157894736842, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787375, Length=234, Percent_Identity=29.0598290598291, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87082012, Length=231, Percent_Identity=29.004329004329, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27442; Mature: 27442

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNQKVRILIVEDDPDMAELISDLVEAEGWIPTCAGSAEEATDILAREQMHLVLVDHNLP
CCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCEEEEEEECCCC
RTSGRAFAQKLRSEINIGIVMVTAAGSAADRVLGLETAADDYVVKPFEPIELTARIKAVL
CCCHHHHHHHHHHHCCCEEEEEEECCCHHHHHEECCCCCCCCEECCCCCHHHHHHHHHHH
RRTVPSLKQEKESEREHERPSLLLGDWAIDLMGRQAVCLADRSKTLTTAEFALLEILAQT
HHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHC
PNQPVSRAQILDRLGSESDRYIDRNVDVLVLRLRRKIERNPDLPRHIKTRRGKGYVLHTG
CCCCHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCEEEEECC
DGEPSA
CCCCCC
>Mature Secondary Structure
MLNQKVRILIVEDDPDMAELISDLVEAEGWIPTCAGSAEEATDILAREQMHLVLVDHNLP
CCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCEEEEEEECCCC
RTSGRAFAQKLRSEINIGIVMVTAAGSAADRVLGLETAADDYVVKPFEPIELTARIKAVL
CCCHHHHHHHHHHHCCCEEEEEEECCCHHHHHEECCCCCCCCEECCCCCHHHHHHHHHHH
RRTVPSLKQEKESEREHERPSLLLGDWAIDLMGRQAVCLADRSKTLTTAEFALLEILAQT
HHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHC
PNQPVSRAQILDRLGSESDRYIDRNVDVLVLRLRRKIERNPDLPRHIKTRRGKGYVLHTG
CCCCHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCEEEEECC
DGEPSA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]