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The map label for this gene is zraS [C]

Identifier: 209549360

GI number: 209549360

Start: 1805813

End: 1807918

Strand: Direct

Name: zraS [C]

Synonym: Rleg2_1764

Alternate gene names: 209549360

Gene position: 1805813-1807918 (Clockwise)

Preceding gene: 209549359

Following gene: 209549363

Centisome position: 39.79

GC content: 61.4

Gene sequence:

>2106_bases
GTGATCAGCCGCTCCTTTCTGTCGTCGATTGCCTTTCGCTTGCCTTTCGCGATTGCCTTCATCTGCTTCCTGGTTTTCAG
TCTTTCAGCGATCGCGATCTACGGGCTGCAGCGCGCCCGTGACGAAATGGCTGCCTATGGCCTACAGGCCTTCACGAGCC
TGGCCAAAGCCTCGCTTGTTTCCCGGCAAGTATCCGATCTGGTGTCGAGCGCGCCCTTCCTGATGAACTCGACCTCGCCC
TACCGGGTGGCGAGCGAGAGCCGCGCTGTCGTGCTGCAGGTCGACAGCCTGCTGAAGACGGCCGAGCCGCACGGAGCAGA
CCAGTCTGCGCGCGGCTTTGCCAGCGCGAGGATGGTTGAGCTTCTCGACCTTATCAGGACACAGACGCTTGTGCTTGCCA
GGGACGCCGACGCCGCCCAGAACCACAAGGCTGAAGCCGCGGCGGCGCTAGGGGAGGTGGCGACCGGCAAGGGCATTGTC
GATCCCGATCTGCGCCGTCAAGTGAACGGAATCGTGCAAGCGGCTTCCACCTCCGACAGTCTTTTCCAGCTTGGCGAACT
TCGCAGGCGATACGTGGCGGGTACCACCAAGGCGCAAGGGGGGACCGAGCCGGAGTCGAGGATTTCGCCTGCCGAGTTGC
AGCCGTATGAGCGCGTGTTCGAAGCTCAAACACGATACCTTTTGAATATGTTCGCGATCCGGGCGGCGGTCGCAAAGCTG
CATGCCGTCTCCCGCGACCTCTCTCATGCAACGGAGACGCAAAGCGATGCAGTTGCACGCCAGCTGAATGACGATCTGCT
TTCGACCTCCGATGCCTTGAGCCGGCTCCTGGTCACCGTGGCCTTGGCTTTTCTGCTCGTGCTCGTCATGGCCATATTCT
CCATCCGGTCGGTCATGCGCGTGTCACGGGGCATCGTGGCGCTGTCGAACGGCATGAATGCGCTCGCCAAGGGTGAAAAC
GAAGTGGGGCCGCCAGCCTACGGCGGAAATGAAACCGAGCTTGTGCGTCTGCTGGATGCGTTCCGCGCCTTCAAGGACAG
CGTGGATCGCGTGTCTCGATTAAGACGCACGGCAGAAGCCGCCGCCCGCACCATCCGGTCGACCTTTCGCAACATGAACG
AGGGGATCGCGCTTTTCGACAAGATGGGGCGACCGATCACCATGAACAGGCGGATCATCGAACTGTTTGGCCACTCGGGT
TCCGCGCGCAAATTGCCGCTGCGCCGGTTTGTCGAGCCCGTGCCGGAGATTGATCCCGCCTTGCTGCCCTCAGATCCGGA
CCGCGGCGCCCTGTTGGAGCGTGCCGTCATCCGCCATCGGACCGGTGACCAGCGGGTAGTTGAGATTTCCATGTCACGAC
AGCCGGAGGGCGGCATCGTTCTTCTTGCGCGCGACGTAACGCTGATGGATCGACAGGAGGCGGAAGCGGCAAAGGTTCAG
CGGCTGGACGGTATCATGCGCATGACGCATCAGGTGAGCCACGAAGTGGGCAACATGATCGGCATCATCACCGGCAGCCT
CGGCCTTCTGGAGCGTGAAACCGGCTTCAACGATCGGCAAAAACGCAACATTGCCCGGATCCGCAAGGCGGCCGAGAGGG
GACGATCGCTAGCCGGCAGCATGTTATCGATCGGCAGCCAGCAGCCGTTCTATCCAAGCCCGGTGGATGTCGGCAGTCTC
CTCCGCGGGATGGCCGATATCCTGGAGATCGCTGTCGGTGCAAAGTGCCATATAAAGCTGGAGCTGGATGCTGACCTGCC
GGTCGTATCGCTCGACGCGGCTCTCTTGGAACAGTCCGTTCTGAACCTCTGTCTCAACGCTTCGGCAGCGATGCCGCTGG
GAGGCATCATCGTTATCGGCGCGACGGCAACGACGGAAATCTTGCTGATTTCGGTGACCGACAGCGGCATAGGCATGAGC
CCAGAGGTGATAGACAAAGCTTTCGAGCCCTATTTCACCACGCGAGGTTCCCACGGTGGAGCAGGGCTCGGCCTTGCCAT
GGTGTACGGCTTTGTCCGTCAGAGCGGCGGGGAGGCGTCCATCTATTCCTCTCCCGGAAACGGAACGACCGTCAGGCTTA
GCTTCCCGACCGGTTTGCGCTCTTAA

Upstream 100 bases:

>100_bases
TCCGGCGGAAAATCGAACGCAATCCCGACCTTCCGCGCCATATCAAGACACGACGCGGAAAGGGCTATGTCCTGCACACT
GGCGACGGCGAGCCGTCAGC

Downstream 100 bases:

>100_bases
TCAGCGGTCAGGAGGTGCCACCAGATTAACGCTCATTGCGCTCGAAAAACCACGCGAGCAGGATGCCGGTGAAGAGCATG
CCGGCCGCGACGAAGATCGT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 701; Mature: 701

Protein sequence:

>701_residues
MISRSFLSSIAFRLPFAIAFICFLVFSLSAIAIYGLQRARDEMAAYGLQAFTSLAKASLVSRQVSDLVSSAPFLMNSTSP
YRVASESRAVVLQVDSLLKTAEPHGADQSARGFASARMVELLDLIRTQTLVLARDADAAQNHKAEAAAALGEVATGKGIV
DPDLRRQVNGIVQAASTSDSLFQLGELRRRYVAGTTKAQGGTEPESRISPAELQPYERVFEAQTRYLLNMFAIRAAVAKL
HAVSRDLSHATETQSDAVARQLNDDLLSTSDALSRLLVTVALAFLLVLVMAIFSIRSVMRVSRGIVALSNGMNALAKGEN
EVGPPAYGGNETELVRLLDAFRAFKDSVDRVSRLRRTAEAAARTIRSTFRNMNEGIALFDKMGRPITMNRRIIELFGHSG
SARKLPLRRFVEPVPEIDPALLPSDPDRGALLERAVIRHRTGDQRVVEISMSRQPEGGIVLLARDVTLMDRQEAEAAKVQ
RLDGIMRMTHQVSHEVGNMIGIITGSLGLLERETGFNDRQKRNIARIRKAAERGRSLAGSMLSIGSQQPFYPSPVDVGSL
LRGMADILEIAVGAKCHIKLELDADLPVVSLDAALLEQSVLNLCLNASAAMPLGGIIVIGATATTEILLISVTDSGIGMS
PEVIDKAFEPYFTTRGSHGGAGLGLAMVYGFVRQSGGEASIYSSPGNGTTVRLSFPTGLRS

Sequences:

>Translated_701_residues
MISRSFLSSIAFRLPFAIAFICFLVFSLSAIAIYGLQRARDEMAAYGLQAFTSLAKASLVSRQVSDLVSSAPFLMNSTSP
YRVASESRAVVLQVDSLLKTAEPHGADQSARGFASARMVELLDLIRTQTLVLARDADAAQNHKAEAAAALGEVATGKGIV
DPDLRRQVNGIVQAASTSDSLFQLGELRRRYVAGTTKAQGGTEPESRISPAELQPYERVFEAQTRYLLNMFAIRAAVAKL
HAVSRDLSHATETQSDAVARQLNDDLLSTSDALSRLLVTVALAFLLVLVMAIFSIRSVMRVSRGIVALSNGMNALAKGEN
EVGPPAYGGNETELVRLLDAFRAFKDSVDRVSRLRRTAEAAARTIRSTFRNMNEGIALFDKMGRPITMNRRIIELFGHSG
SARKLPLRRFVEPVPEIDPALLPSDPDRGALLERAVIRHRTGDQRVVEISMSRQPEGGIVLLARDVTLMDRQEAEAAKVQ
RLDGIMRMTHQVSHEVGNMIGIITGSLGLLERETGFNDRQKRNIARIRKAAERGRSLAGSMLSIGSQQPFYPSPVDVGSL
LRGMADILEIAVGAKCHIKLELDADLPVVSLDAALLEQSVLNLCLNASAAMPLGGIIVIGATATTEILLISVTDSGIGMS
PEVIDKAFEPYFTTRGSHGGAGLGLAMVYGFVRQSGGEASIYSSPGNGTTVRLSFPTGLRS
>Mature_701_residues
MISRSFLSSIAFRLPFAIAFICFLVFSLSAIAIYGLQRARDEMAAYGLQAFTSLAKASLVSRQVSDLVSSAPFLMNSTSP
YRVASESRAVVLQVDSLLKTAEPHGADQSARGFASARMVELLDLIRTQTLVLARDADAAQNHKAEAAAALGEVATGKGIV
DPDLRRQVNGIVQAASTSDSLFQLGELRRRYVAGTTKAQGGTEPESRISPAELQPYERVFEAQTRYLLNMFAIRAAVAKL
HAVSRDLSHATETQSDAVARQLNDDLLSTSDALSRLLVTVALAFLLVLVMAIFSIRSVMRVSRGIVALSNGMNALAKGEN
EVGPPAYGGNETELVRLLDAFRAFKDSVDRVSRLRRTAEAAARTIRSTFRNMNEGIALFDKMGRPITMNRRIIELFGHSG
SARKLPLRRFVEPVPEIDPALLPSDPDRGALLERAVIRHRTGDQRVVEISMSRQPEGGIVLLARDVTLMDRQEAEAAKVQ
RLDGIMRMTHQVSHEVGNMIGIITGSLGLLERETGFNDRQKRNIARIRKAAERGRSLAGSMLSIGSQQPFYPSPVDVGSL
LRGMADILEIAVGAKCHIKLELDADLPVVSLDAALLEQSVLNLCLNASAAMPLGGIIVIGATATTEILLISVTDSGIGMS
PEVIDKAFEPYFTTRGSHGGAGLGLAMVYGFVRQSGGEASIYSSPGNGTTVRLSFPTGLRS

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=227, Percent_Identity=29.0748898678414, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788549, Length=264, Percent_Identity=26.1363636363636, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI48994928, Length=150, Percent_Identity=30, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1790300, Length=262, Percent_Identity=24.4274809160305, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87081816, Length=217, Percent_Identity=26.2672811059908, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 75559; Mature: 75559

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISRSFLSSIAFRLPFAIAFICFLVFSLSAIAIYGLQRARDEMAAYGLQAFTSLAKASLV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRQVSDLVSSAPFLMNSTSPYRVASESRAVVLQVDSLLKTAEPHGADQSARGFASARMVE
HHHHHHHHHCCCHHCCCCCCCEECCCCCEEEEEHHHHHHHCCCCCCCCHHHHHHHHHHHH
LLDLIRTQTLVLARDADAAQNHKAEAAAALGEVATGKGIVDPDLRRQVNGIVQAASTSDS
HHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHH
LFQLGELRRRYVAGTTKAQGGTEPESRISPAELQPYERVFEAQTRYLLNMFAIRAAVAKL
HHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HAVSRDLSHATETQSDAVARQLNDDLLSTSDALSRLLVTVALAFLLVLVMAIFSIRSVMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSRGIVALSNGMNALAKGENEVGPPAYGGNETELVRLLDAFRAFKDSVDRVSRLRRTAEA
HHHCHHEECCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AARTIRSTFRNMNEGIALFDKMGRPITMNRRIIELFGHSGSARKLPLRRFVEPVPEIDPA
HHHHHHHHHHHHHCHHHHHHHCCCCEECCCHHHHHHCCCCCCCCCCHHHHHCCCCCCCCC
LLPSDPDRGALLERAVIRHRTGDQRVVEISMSRQPEGGIVLLARDVTLMDRQEAEAAKVQ
CCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHH
RLDGIMRMTHQVSHEVGNMIGIITGSLGLLERETGFNDRQKRNIARIRKAAERGRSLAGS
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MLSIGSQQPFYPSPVDVGSLLRGMADILEIAVGAKCHIKLELDADLPVVSLDAALLEQSV
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEHHHHHHHHHHH
LNLCLNASAAMPLGGIIVIGATATTEILLISVTDSGIGMSPEVIDKAFEPYFTTRGSHGG
HHHHHCCCCCCCCCCEEEEECCCCEEEEEEEEECCCCCCCHHHHHHHHCCHHCCCCCCCC
AGLGLAMVYGFVRQSGGEASIYSSPGNGTTVRLSFPTGLRS
CHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEECCCCCCC
>Mature Secondary Structure
MISRSFLSSIAFRLPFAIAFICFLVFSLSAIAIYGLQRARDEMAAYGLQAFTSLAKASLV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRQVSDLVSSAPFLMNSTSPYRVASESRAVVLQVDSLLKTAEPHGADQSARGFASARMVE
HHHHHHHHHCCCHHCCCCCCCEECCCCCEEEEEHHHHHHHCCCCCCCCHHHHHHHHHHHH
LLDLIRTQTLVLARDADAAQNHKAEAAAALGEVATGKGIVDPDLRRQVNGIVQAASTSDS
HHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHH
LFQLGELRRRYVAGTTKAQGGTEPESRISPAELQPYERVFEAQTRYLLNMFAIRAAVAKL
HHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HAVSRDLSHATETQSDAVARQLNDDLLSTSDALSRLLVTVALAFLLVLVMAIFSIRSVMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSRGIVALSNGMNALAKGENEVGPPAYGGNETELVRLLDAFRAFKDSVDRVSRLRRTAEA
HHHCHHEECCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AARTIRSTFRNMNEGIALFDKMGRPITMNRRIIELFGHSGSARKLPLRRFVEPVPEIDPA
HHHHHHHHHHHHHCHHHHHHHCCCCEECCCHHHHHHCCCCCCCCCCHHHHHCCCCCCCCC
LLPSDPDRGALLERAVIRHRTGDQRVVEISMSRQPEGGIVLLARDVTLMDRQEAEAAKVQ
CCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHH
RLDGIMRMTHQVSHEVGNMIGIITGSLGLLERETGFNDRQKRNIARIRKAAERGRSLAGS
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MLSIGSQQPFYPSPVDVGSLLRGMADILEIAVGAKCHIKLELDADLPVVSLDAALLEQSV
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEHHHHHHHHHHH
LNLCLNASAAMPLGGIIVIGATATTEILLISVTDSGIGMSPEVIDKAFEPYFTTRGSHGG
HHHHHCCCCCCCCCCEEEEECCCCEEEEEEEEECCCCCCCHHHHHHHHCCHHCCCCCCCC
AGLGLAMVYGFVRQSGGEASIYSSPGNGTTVRLSFPTGLRS
CHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA