Click here to switch to the map view.

The map label for this gene is coaD [H]

Identifier: 209549344

GI number: 209549344

Start: 1790168

End: 1790662

Strand: Direct

Name: coaD [H]

Synonym: Rleg2_1748

Alternate gene names: 209549344

Gene position: 1790168-1790662 (Clockwise)

Preceding gene: 209549340

Following gene: 209549345

Centisome position: 39.45

GC content: 62.83

Gene sequence:

>495_bases
ATGACGACAGCTTTTTATCCCGGGTCCTTCGACCCGATCACCAATGGGCACGTGGATGTTCTGGTCCAGGCGCTGAACGT
CGCCGAAAAGGTGATCGTCGCGATCGGCATCCATCCCGGCAAGGCGCCGCTCTTTTCCTTCGAGGAGAGAGCCGAGCTGA
TCCGCCTGTCGCTGGCTGAAGTGCTGCCCGGCAAGACCGGCGACATCGACGTCGTCGCCTTTGACAATCTGGTCGTCGAT
GCCGCCCGCAGCCATGGCGCCACGCTTTTGATCCGCGGTCTTCGCGACGGCACCGATCTTGATTACGAAATGCAGATGGC
CGGGATGAACCGGACGATGGCGCCTGATATCCAGACCATCTTTTTGCCGGCGGGCACGGCCTCGCGGCCCATTACCGCCA
CATTGGTCCGCCAGATCGCCGCCATGGGCGGCGATGTCAGCGCCTTCGTGCCGGCCGCCGTCTTGCAAGCCCTCACATCC
AAGCGCCCAGACTGA

Upstream 100 bases:

>100_bases
GTTCAACCGTCCGGGATGATTGGCCAAATCACTTGCGGCCAAATGACTTGCGAGAAGGCAGCATCCGTGACAAAAGGCGT
CAAACCAACGGTCGGGCCAG

Downstream 100 bases:

>100_bases
CGAGTACAAGTCTAACAAGTACAAAGTCTGATAAGAACCAAGTCCAGCAAGCGCAAAGACCAGGCGGAACCCGCCGCAAC
GGAGCCCACATGAAACTCTT

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MTTAFYPGSFDPITNGHVDVLVQALNVAEKVIVAIGIHPGKAPLFSFEERAELIRLSLAEVLPGKTGDIDVVAFDNLVVD
AARSHGATLLIRGLRDGTDLDYEMQMAGMNRTMAPDIQTIFLPAGTASRPITATLVRQIAAMGGDVSAFVPAAVLQALTS
KRPD

Sequences:

>Translated_164_residues
MTTAFYPGSFDPITNGHVDVLVQALNVAEKVIVAIGIHPGKAPLFSFEERAELIRLSLAEVLPGKTGDIDVVAFDNLVVD
AARSHGATLLIRGLRDGTDLDYEMQMAGMNRTMAPDIQTIFLPAGTASRPITATLVRQIAAMGGDVSAFVPAAVLQALTS
KRPD
>Mature_163_residues
TTAFYPGSFDPITNGHVDVLVQALNVAEKVIVAIGIHPGKAPLFSFEERAELIRLSLAEVLPGKTGDIDVVAFDNLVVDA
ARSHGATLLIRGLRDGTDLDYEMQMAGMNRTMAPDIQTIFLPAGTASRPITATLVRQIAAMGGDVSAFVPAAVLQALTSK
RPD

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=158, Percent_Identity=43.0379746835443, Blast_Score=145, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 17386; Mature: 17255

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAFYPGSFDPITNGHVDVLVQALNVAEKVIVAIGIHPGKAPLFSFEERAELIRLSLAE
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHH
VLPGKTGDIDVVAFDNLVVDAARSHGATLLIRGLRDGTDLDYEMQMAGMNRTMAPDIQTI
HCCCCCCCEEEEEECCHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCEEE
FLPAGTASRPITATLVRQIAAMGGDVSAFVPAAVLQALTSKRPD
EEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TTAFYPGSFDPITNGHVDVLVQALNVAEKVIVAIGIHPGKAPLFSFEERAELIRLSLAE
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHH
VLPGKTGDIDVVAFDNLVVDAARSHGATLLIRGLRDGTDLDYEMQMAGMNRTMAPDIQTI
HCCCCCCCEEEEEECCHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCEEE
FLPAGTASRPITATLVRQIAAMGGDVSAFVPAAVLQALTSKRPD
EEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA