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The map label for this gene is hflX [H]

Identifier: 209549232

GI number: 209549232

Start: 1662949

End: 1664274

Strand: Direct

Name: hflX [H]

Synonym: Rleg2_1633

Alternate gene names: 209549232

Gene position: 1662949-1664274 (Clockwise)

Preceding gene: 209549231

Following gene: 209549235

Centisome position: 36.65

GC content: 64.93

Gene sequence:

>1326_bases
ATGCGCGCGACCGTCGTCGTGCCGGTCCTGAAATCGCGCAGCCGCGGCGGCCAGAGCGAATCGGCCTCGACCCGCACACC
GGAAAGCCGGCTCGAAGAAGCGACAGGGCTTGCCCAGGCGATCGACCTCGATGTCGTCACTGGCTCGATCGTGCCGGTCA
ATGATCCGCGACCGGCGACATTGCTCGGCACCGGCAAGATCGAGGAGATCAAGGCGCTGCTCAACGAGCGCGATTCCGGT
CTCGTCATCGTCGATCATCCGCTGACGCCGGTGCAGCAGCGCAATCTCGAAAAGGAATGGAACGCCAAGGTCATCGACCG
CACGGGCCTCATCCTCGAAATCTTCGGCCGTCGCGCCTCCACCAAGGAAGGCACGCTGCAGGTCGATCTCGCCCACCTGA
ATTATCAGAAGGGCAGGCTGGTTCGAAGCTGGACCCACCTTGAACGCCAGCGCGGCGGCGGCGGCTTCATGGGCGGCCCC
GGCGAAACCCAGATCGAAGCCGACCGGCGGATGCTGCAGGATCGCATCATCAAGCTCGAACGCGAGTTGGAGCAGGTCGT
GCGCACCCGCCAGCTCCATCGCGCCAAGCGCCGTAAGGTGCCGCACCCGATCGTGGCGCTGGTCGGCTATACCAATGCCG
GCAAATCGACGCTGTTCAACCGCATCACCGGCGCCGGCGTGCTGGCCGAAGACATGCTCTTTGCCACGCTCGACCCGACG
CTGCGCCGCATGAAGCTGCCACACGGCCGCACCGTCATCCTGTCCGACACCGTGGGCTTCATCTCCGATCTGCCGACCCA
TCTGGTCGCCGCCTTCCGCGCGACGCTGGAAGAGGTGCTGGAAGCCGATCTCATCCTGCATGTCCGTGATATGTCCGATC
CCGACAACCAGGCGCAAAGCTCCGACGTGATGCGCATCCTCGGCGATCTCGGCATCGACGAGGCCGAAGCGGCGAAGCGG
CTGATCGAGGTCTGGAACAAGATCGACCGGCTGGAGCCCGAGGTGCACGACACCATGGTGCAGAAGTCGGCGGGTGCGAC
CAACGTCGTCGCCGTCTCGGCCGTCAGCGGCGAGGGCGTCGACACGCTGATGGACGAGATCAGCCGCCGGCTTTCCGGCG
TCATGACCGAAACGACCGTCCGCCTTCCCGTCGACAAGCTGGCGCTGCTGCCCTGGCTCTACGACCACGCAATCGTCGAC
GGCCGCGAGGACAATGAAGACGGCTCGATCACGCTGGAGCTGCGCCTCTCCGAAACCGAAGCCACCGAACTCGAACGCCG
CATCGGCAACGGCCCGAAATCTTCGAAGGAAGATTGGGAGCGGTAA

Upstream 100 bases:

>100_bases
AGAGCGAAGAAGCAGCGTCCTAACAGGATCAGCCGTCATTTCGACACGCGATACCAAGAACGATTCGATCATCCCTGAGG
CCGCCAAGCACAGGGACGAC

Downstream 100 bases:

>100_bases
AGCACTCGGCACGCCCTTCATTCTGCCCTTCGCTTGCGCTCAGGATGAGCTATCTCTGGCGACTCTAACCCACCCTCCGT
CGTCCTCGGCCTTGAGCCGA

Product: GTP-binding proten HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MRATVVVPVLKSRSRGGQSESASTRTPESRLEEATGLAQAIDLDVVTGSIVPVNDPRPATLLGTGKIEEIKALLNERDSG
LVIVDHPLTPVQQRNLEKEWNAKVIDRTGLILEIFGRRASTKEGTLQVDLAHLNYQKGRLVRSWTHLERQRGGGGFMGGP
GETQIEADRRMLQDRIIKLERELEQVVRTRQLHRAKRRKVPHPIVALVGYTNAGKSTLFNRITGAGVLAEDMLFATLDPT
LRRMKLPHGRTVILSDTVGFISDLPTHLVAAFRATLEEVLEADLILHVRDMSDPDNQAQSSDVMRILGDLGIDEAEAAKR
LIEVWNKIDRLEPEVHDTMVQKSAGATNVVAVSAVSGEGVDTLMDEISRRLSGVMTETTVRLPVDKLALLPWLYDHAIVD
GREDNEDGSITLELRLSETEATELERRIGNGPKSSKEDWER

Sequences:

>Translated_441_residues
MRATVVVPVLKSRSRGGQSESASTRTPESRLEEATGLAQAIDLDVVTGSIVPVNDPRPATLLGTGKIEEIKALLNERDSG
LVIVDHPLTPVQQRNLEKEWNAKVIDRTGLILEIFGRRASTKEGTLQVDLAHLNYQKGRLVRSWTHLERQRGGGGFMGGP
GETQIEADRRMLQDRIIKLERELEQVVRTRQLHRAKRRKVPHPIVALVGYTNAGKSTLFNRITGAGVLAEDMLFATLDPT
LRRMKLPHGRTVILSDTVGFISDLPTHLVAAFRATLEEVLEADLILHVRDMSDPDNQAQSSDVMRILGDLGIDEAEAAKR
LIEVWNKIDRLEPEVHDTMVQKSAGATNVVAVSAVSGEGVDTLMDEISRRLSGVMTETTVRLPVDKLALLPWLYDHAIVD
GREDNEDGSITLELRLSETEATELERRIGNGPKSSKEDWER
>Mature_441_residues
MRATVVVPVLKSRSRGGQSESASTRTPESRLEEATGLAQAIDLDVVTGSIVPVNDPRPATLLGTGKIEEIKALLNERDSG
LVIVDHPLTPVQQRNLEKEWNAKVIDRTGLILEIFGRRASTKEGTLQVDLAHLNYQKGRLVRSWTHLERQRGGGGFMGGP
GETQIEADRRMLQDRIIKLERELEQVVRTRQLHRAKRRKVPHPIVALVGYTNAGKSTLFNRITGAGVLAEDMLFATLDPT
LRRMKLPHGRTVILSDTVGFISDLPTHLVAAFRATLEEVLEADLILHVRDMSDPDNQAQSSDVMRILGDLGIDEAEAAKR
LIEVWNKIDRLEPEVHDTMVQKSAGATNVVAVSAVSGEGVDTLMDEISRRLSGVMTETTVRLPVDKLALLPWLYDHAIVD
GREDNEDGSITLELRLSETEATELERRIGNGPKSSKEDWER

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=266, Percent_Identity=37.593984962406, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI310133116, Length=266, Percent_Identity=37.593984962406, Blast_Score=142, Evalue=8e-34,
Organism=Homo sapiens, GI310124269, Length=247, Percent_Identity=38.0566801619433, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI310124267, Length=247, Percent_Identity=38.0566801619433, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI310124171, Length=247, Percent_Identity=38.0566801619433, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI310124169, Length=247, Percent_Identity=38.0566801619433, Blast_Score=140, Evalue=2e-33,
Organism=Escherichia coli, GI1790615, Length=374, Percent_Identity=46.524064171123, Blast_Score=292, Evalue=3e-80,
Organism=Caenorhabditis elegans, GI17561038, Length=437, Percent_Identity=29.7482837528604, Blast_Score=194, Evalue=6e-50,
Organism=Drosophila melanogaster, GI24650079, Length=404, Percent_Identity=35.1485148514851, Blast_Score=161, Evalue=9e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48867; Mature: 48867

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRATVVVPVLKSRSRGGQSESASTRTPESRLEEATGLAQAIDLDVVTGSIVPVNDPRPAT
CCCEEEEHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECCEEECCCCCCCE
LLGTGKIEEIKALLNERDSGLVIVDHPLTPVQQRNLEKEWNAKVIDRTGLILEIFGRRAS
EEECCCHHHHHHHHCCCCCCEEEECCCCCCHHHHCCCHHCCCEEECCCCHHHHHHCCCCC
TKEGTLQVDLAHLNYQKGRLVRSWTHLERQRGGGGFMGGPGETQIEADRRMLQDRIIKLE
CCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RELEQVVRTRQLHRAKRRKVPHPIVALVGYTNAGKSTLFNRITGAGVLAEDMLFATLDPT
HHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHCCHH
LRRMKLPHGRTVILSDTVGFISDLPTHLVAAFRATLEEVLEADLILHVRDMSDPDNQAQS
HHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHH
SDVMRILGDLGIDEAEAAKRLIEVWNKIDRLEPEVHDTMVQKSAGATNVVAVSAVSGEGV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEECCCCCH
DTLMDEISRRLSGVMTETTVRLPVDKLALLPWLYDHAIVDGREDNEDGSITLELRLSETE
HHHHHHHHHHHHHHHHHCEEECCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCH
ATELERRIGNGPKSSKEDWER
HHHHHHHHCCCCCCCHHHCCC
>Mature Secondary Structure
MRATVVVPVLKSRSRGGQSESASTRTPESRLEEATGLAQAIDLDVVTGSIVPVNDPRPAT
CCCEEEEHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECCEEECCCCCCCE
LLGTGKIEEIKALLNERDSGLVIVDHPLTPVQQRNLEKEWNAKVIDRTGLILEIFGRRAS
EEECCCHHHHHHHHCCCCCCEEEECCCCCCHHHHCCCHHCCCEEECCCCHHHHHHCCCCC
TKEGTLQVDLAHLNYQKGRLVRSWTHLERQRGGGGFMGGPGETQIEADRRMLQDRIIKLE
CCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RELEQVVRTRQLHRAKRRKVPHPIVALVGYTNAGKSTLFNRITGAGVLAEDMLFATLDPT
HHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHCCHH
LRRMKLPHGRTVILSDTVGFISDLPTHLVAAFRATLEEVLEADLILHVRDMSDPDNQAQS
HHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHH
SDVMRILGDLGIDEAEAAKRLIEVWNKIDRLEPEVHDTMVQKSAGATNVVAVSAVSGEGV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEECCCCCH
DTLMDEISRRLSGVMTETTVRLPVDKLALLPWLYDHAIVDGREDNEDGSITLELRLSETE
HHHHHHHHHHHHHHHHHCEEECCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCH
ATELERRIGNGPKSSKEDWER
HHHHHHHHCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]