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The map label for this gene is frr [H]

Identifier: 209549185

GI number: 209549185

Start: 1611099

End: 1611659

Strand: Direct

Name: frr [H]

Synonym: Rleg2_1586

Alternate gene names: 209549185

Gene position: 1611099-1611659 (Clockwise)

Preceding gene: 209549184

Following gene: 209549186

Centisome position: 35.5

GC content: 59.71

Gene sequence:

>561_bases
ATGACTGAAGGTATCGACATCAAGGAACTGAAGCGCCGCATGGACGGCGCGGTTTCCGCATTCAAGAGCGACATCGCATC
GCTGCGCACCGGCCGCGCTTCGGCCAACATCCTCGATCCGGTCACGATCGAGGCCTATGGTTCGCGCATGCCGCTGAACC
AGGTCGCCAATATCACTGTGCCCGAGCCGCGCATGCTGTCGGTTTCCGTCTGGGACAAGTCGATGGTCAGCGCCGTCGAG
CGCGGCATTCGCGAATCCAATCTCGGCCTCAACCCGATCGTCGACGGCCAGAGCCTGCGCATTCCGCTGCCCGAACTGAA
CGAGGAGCGCCGCAAGTCGCTCGTCAAGGTGGCTCATGACTATGCCGAAAAGAGCAAGGTCGCGATTCGCCATGTTCGCC
GTGACGGTATGGACGGCCTTAAGAAGGCCGAAAAAGATGGCGTAATCGGCCAGGACGAGGGCAGGGCGCAGTCGGAACGT
GTACAGAAGATGACCGACGAGACGATTTCCGAAATCGACCGCTTGCTTGGCGAGAAGGAAAAGGAAATCATGCAGGTCTA
G

Upstream 100 bases:

>100_bases
GGGCGGTGGCCTCAAGACCATCGTCTCCGACAACTGATATAGACTGCGCCGCCTTTGTCAGGCGCAGCCATCGCGACGCG
CTTTATACGGGAGCATCGAC

Downstream 100 bases:

>100_bases
TGGATCTGTGCCTTTGCCTGGAAAGACCGGACGGGAAATGTCGGAATCTGTATTTGTGACTGTGCCAGAGCATGTTGCCA
TCATCATGGACGGCAATGGC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MTEGIDIKELKRRMDGAVSAFKSDIASLRTGRASANILDPVTIEAYGSRMPLNQVANITVPEPRMLSVSVWDKSMVSAVE
RGIRESNLGLNPIVDGQSLRIPLPELNEERRKSLVKVAHDYAEKSKVAIRHVRRDGMDGLKKAEKDGVIGQDEGRAQSER
VQKMTDETISEIDRLLGEKEKEIMQV

Sequences:

>Translated_186_residues
MTEGIDIKELKRRMDGAVSAFKSDIASLRTGRASANILDPVTIEAYGSRMPLNQVANITVPEPRMLSVSVWDKSMVSAVE
RGIRESNLGLNPIVDGQSLRIPLPELNEERRKSLVKVAHDYAEKSKVAIRHVRRDGMDGLKKAEKDGVIGQDEGRAQSER
VQKMTDETISEIDRLLGEKEKEIMQV
>Mature_185_residues
TEGIDIKELKRRMDGAVSAFKSDIASLRTGRASANILDPVTIEAYGSRMPLNQVANITVPEPRMLSVSVWDKSMVSAVER
GIRESNLGLNPIVDGQSLRIPLPELNEERRKSLVKVAHDYAEKSKVAIRHVRRDGMDGLKKAEKDGVIGQDEGRAQSERV
QKMTDETISEIDRLLGEKEKEIMQV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=182, Percent_Identity=31.8681318681319, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI291042689, Length=148, Percent_Identity=34.4594594594595, Blast_Score=93, Evalue=1e-19,
Organism=Escherichia coli, GI1786368, Length=179, Percent_Identity=46.927374301676, Blast_Score=167, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24661488, Length=185, Percent_Identity=29.1891891891892, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20738; Mature: 20607

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEGIDIKELKRRMDGAVSAFKSDIASLRTGRASANILDPVTIEAYGSRMPLNQVANITV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHCCCCCCHHHHCCCCC
PEPRMLSVSVWDKSMVSAVERGIRESNLGLNPIVDGQSLRIPLPELNEERRKSLVKVAHD
CCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
YAEKSKVAIRHVRRDGMDGLKKAEKDGVIGQDEGRAQSERVQKMTDETISEIDRLLGEKE
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
KEIMQV
HHHHCC
>Mature Secondary Structure 
TEGIDIKELKRRMDGAVSAFKSDIASLRTGRASANILDPVTIEAYGSRMPLNQVANITV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHCCCCCCHHHHCCCCC
PEPRMLSVSVWDKSMVSAVERGIRESNLGLNPIVDGQSLRIPLPELNEERRKSLVKVAHD
CCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
YAEKSKVAIRHVRRDGMDGLKKAEKDGVIGQDEGRAQSERVQKMTDETISEIDRLLGEKE
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
KEIMQV
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA