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The map label for this gene is pyrH [H]

Identifier: 209549184

GI number: 209549184

Start: 1610313

End: 1611035

Strand: Direct

Name: pyrH [H]

Synonym: Rleg2_1585

Alternate gene names: 209549184

Gene position: 1610313-1611035 (Clockwise)

Preceding gene: 209549183

Following gene: 209549185

Centisome position: 35.49

GC content: 61.69

Gene sequence:

>723_bases
ATGTCTTTAGAGCCTGTCTATAAACGCGTTCTACTCAAGGCTTCCGGCGAAGCGCTCATGGGTAGCCAGGGTTTCGGGAT
CGATGTTGCGGTGGCGGACCGCATTGCATCCGATATCGCCGAAGCAAGGCATATGGGCGTGGAAGTCGGCGTCGTCGTCG
GTGGCGGCAATATTTTCCGCGGTGTCGCGGTCGCGTCCAAGGGCGGTGACCGGGTCACCGGCGACCACATGGGCATGCTC
GGCACTATCATCAATGCGCTGGCGCTGGCGACCTCGCTGCGCAAGCTCAACATCGATACGGTGGTGCTTTCGGCCATCTC
CATGCCCGAGATCTGCGAGAGCTTCTCGCAGCGCGCGACCCTCTATCACCTGTCGATGGGACGTGTGGTGATCTTTGCCG
GCGGCACCGGCAACCCCTTCTTCACCACCGATTCGGCCGCAGCGTTGCGCGCCGCCGAAATGGGCGCGCAAGCGATCTTC
AAGGGCACGCAGGTGGACGGCATCTACACCGCCGACCCGAAGAAATATCCCGATGCGACCCGGCTTGACCGCCTGACGCA
CCAGGAAGTGCTGGACAGGGGGCTTGCGGTAATGGACGTTGCCGCCGTGGCGCTCGCCCGGGAGAATTCCATTCCGATCA
TCGTCTTCTCGATCCACGAGAAAGGCGGTTTTGCTGAAATCCTGACGGGCGGTGGCCTCAAGACCATCGTCTCCGACAAC
TGA

Upstream 100 bases:

>100_bases
TTGATCTTCCAGCCATAGTTGGGAAAACAACAGGGGCATCGCGTGACAACGCGGTGCCCTTCGTGTATCGGGCACTCACG
GCAATTTACGAGGAGCCAAG

Downstream 100 bases:

>100_bases
TATAGACTGCGCCGCCTTTGTCAGGCGCAGCCATCGCGACGCGCTTTATACGGGAGCATCGACATGACTGAAGGTATCGA
CATCAAGGAACTGAAGCGCC

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MSLEPVYKRVLLKASGEALMGSQGFGIDVAVADRIASDIAEARHMGVEVGVVVGGGNIFRGVAVASKGGDRVTGDHMGML
GTIINALALATSLRKLNIDTVVLSAISMPEICESFSQRATLYHLSMGRVVIFAGGTGNPFFTTDSAAALRAAEMGAQAIF
KGTQVDGIYTADPKKYPDATRLDRLTHQEVLDRGLAVMDVAAVALARENSIPIIVFSIHEKGGFAEILTGGGLKTIVSDN

Sequences:

>Translated_240_residues
MSLEPVYKRVLLKASGEALMGSQGFGIDVAVADRIASDIAEARHMGVEVGVVVGGGNIFRGVAVASKGGDRVTGDHMGML
GTIINALALATSLRKLNIDTVVLSAISMPEICESFSQRATLYHLSMGRVVIFAGGTGNPFFTTDSAAALRAAEMGAQAIF
KGTQVDGIYTADPKKYPDATRLDRLTHQEVLDRGLAVMDVAAVALARENSIPIIVFSIHEKGGFAEILTGGGLKTIVSDN
>Mature_239_residues
SLEPVYKRVLLKASGEALMGSQGFGIDVAVADRIASDIAEARHMGVEVGVVVGGGNIFRGVAVASKGGDRVTGDHMGMLG
TIINALALATSLRKLNIDTVVLSAISMPEICESFSQRATLYHLSMGRVVIFAGGTGNPFFTTDSAAALRAAEMGAQAIFK
GTQVDGIYTADPKKYPDATRLDRLTHQEVLDRGLAVMDVAAVALARENSIPIIVFSIHEKGGFAEILTGGGLKTIVSDN

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=236, Percent_Identity=48.3050847457627, Blast_Score=244, Evalue=5e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 25120; Mature: 24989

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLEPVYKRVLLKASGEALMGSQGFGIDVAVADRIASDIAEARHMGVEVGVVVGGGNIFR
CCCCHHHHHHHHHCCCCEEECCCCCCEEHHHHHHHHHHHHHHHHCCEEEEEEEECCCEEE
GVAVASKGGDRVTGDHMGMLGTIINALALATSLRKLNIDTVVLSAISMPEICESFSQRAT
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHCEE
LYHLSMGRVVIFAGGTGNPFFTTDSAAALRAAEMGAQAIFKGTQVDGIYTADPKKYPDAT
EEEEECCCEEEEECCCCCCCEECCHHHHHHHHHHCHHHHHCCCCCCEEEECCCCCCCCHH
RLDRLTHQEVLDRGLAVMDVAAVALARENSIPIIVFSIHEKGGFAEILTGGGLKTIVSDN
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEECCCEEEEECCC
>Mature Secondary Structure 
SLEPVYKRVLLKASGEALMGSQGFGIDVAVADRIASDIAEARHMGVEVGVVVGGGNIFR
CCCHHHHHHHHHCCCCEEECCCCCCEEHHHHHHHHHHHHHHHHCCEEEEEEEECCCEEE
GVAVASKGGDRVTGDHMGMLGTIINALALATSLRKLNIDTVVLSAISMPEICESFSQRAT
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHCEE
LYHLSMGRVVIFAGGTGNPFFTTDSAAALRAAEMGAQAIFKGTQVDGIYTADPKKYPDAT
EEEEECCCEEEEECCCCCCCEECCHHHHHHHHHHCHHHHHCCCCCCEEEECCCCCCCCHH
RLDRLTHQEVLDRGLAVMDVAAVALARENSIPIIVFSIHEKGGFAEILTGGGLKTIVSDN
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEECCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA