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The map label for this gene is map [H]

Identifier: 209549112

GI number: 209549112

Start: 1544461

End: 1545297

Strand: Reverse

Name: map [H]

Synonym: Rleg2_1512

Alternate gene names: 209549112

Gene position: 1545297-1544461 (Counterclockwise)

Preceding gene: 209549113

Following gene: 209549111

Centisome position: 34.05

GC content: 64.4

Gene sequence:

>837_bases
ATGGTGAACTATATCGAAGCCTCTTCCGCGCCCTCGAAGAATACGGGCGCCATCCGGCTTTACGACGCGCAAGCATACGA
GGGCATGCGCAGGGCATGCCAGCTGACCGCGCGCTGCCTCGATGCGCTGGCCGACATCGTCAAGCCGGGGCTGGTGACCG
ATGACATCGACCGGTTCGTCTTCGATTTCGGCATGGATCACGGCGCCCATCCGGCGACGCTGAATTATCGCGGCTACACC
AAATCGACGTGCACCTCGATCAACCATGTCGTCTGCCATGGCATTCCGAACGACAAGCCGCTGCGCGAAGGCGATATCGT
CAATATCGACGTCACCTTCGTGCTCGACGGCTGGCACGGCGATTCCAGCCGGATGTATCCGGTGGGAACGATCAAGCGCG
CCGCCGAGCGACTGCTCGAGGTCACCTATGAATCGCTGATGCGCGGCATTTCCGCCGTCAGGCCCGGCGCCCGCACCGGC
GCAATCGGCGAGGCGATCCAGACCTATGCCGAGGCCGAGCGCTGCTCGGTGGTGCGTGATTTCTGCGGCCACGGCGTCGG
CCGGCTGTTTCACGATTCGCCGAATATCCTGCATTACGGCCGCGCCAATGAGGGACCGGAGCTGCGTGAAGGCATGATCT
TCACCATCGAGCCGATGATCAATCTCGGCCGGCCGCATGTGAAGGTGCTGGCCGACGGCTGGACGGCGGTCACCCGCGAC
CGCTCGCTTTCGGCGCAGTACGAACACACCGTCGGCGTCACCTCCGACGGCTGCGAGATCTTCACTCTGTCGCCCGGCGG
GCTCGACCGCCCCGGCCTGCCATCGCTTGCCGGGTGA

Upstream 100 bases:

>100_bases
GTATCTTTTCAGAAATCTCGCCCCGACGGTTGATCGCGATGGACGAACCCGGCATAGCTGCATTATGAACAATTCTAATA
TTCTCCGCTAAGGCCCTGCA

Downstream 100 bases:

>100_bases
CGATCCGATGGCGAAGAGGCCGGTTGCGACATCTTCCGACGACGAGTTGCCTTTCGAGATCGAAGAGCCTGTTGCCGCCG
ACGAACGCGCGTTCTTCGGC

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MVNYIEASSAPSKNTGAIRLYDAQAYEGMRRACQLTARCLDALADIVKPGLVTDDIDRFVFDFGMDHGAHPATLNYRGYT
KSTCTSINHVVCHGIPNDKPLREGDIVNIDVTFVLDGWHGDSSRMYPVGTIKRAAERLLEVTYESLMRGISAVRPGARTG
AIGEAIQTYAEAERCSVVRDFCGHGVGRLFHDSPNILHYGRANEGPELREGMIFTIEPMINLGRPHVKVLADGWTAVTRD
RSLSAQYEHTVGVTSDGCEIFTLSPGGLDRPGLPSLAG

Sequences:

>Translated_278_residues
MVNYIEASSAPSKNTGAIRLYDAQAYEGMRRACQLTARCLDALADIVKPGLVTDDIDRFVFDFGMDHGAHPATLNYRGYT
KSTCTSINHVVCHGIPNDKPLREGDIVNIDVTFVLDGWHGDSSRMYPVGTIKRAAERLLEVTYESLMRGISAVRPGARTG
AIGEAIQTYAEAERCSVVRDFCGHGVGRLFHDSPNILHYGRANEGPELREGMIFTIEPMINLGRPHVKVLADGWTAVTRD
RSLSAQYEHTVGVTSDGCEIFTLSPGGLDRPGLPSLAG
>Mature_278_residues
MVNYIEASSAPSKNTGAIRLYDAQAYEGMRRACQLTARCLDALADIVKPGLVTDDIDRFVFDFGMDHGAHPATLNYRGYT
KSTCTSINHVVCHGIPNDKPLREGDIVNIDVTFVLDGWHGDSSRMYPVGTIKRAAERLLEVTYESLMRGISAVRPGARTG
AIGEAIQTYAEAERCSVVRDFCGHGVGRLFHDSPNILHYGRANEGPELREGMIFTIEPMINLGRPHVKVLADGWTAVTRD
RSLSAQYEHTVGVTSDGCEIFTLSPGGLDRPGLPSLAG

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=258, Percent_Identity=45.3488372093023, Blast_Score=244, Evalue=5e-65,
Organism=Homo sapiens, GI40385867, Length=249, Percent_Identity=40.9638554216867, Blast_Score=203, Evalue=1e-52,
Organism=Escherichia coli, GI1786364, Length=249, Percent_Identity=50.6024096385542, Blast_Score=251, Evalue=4e-68,
Organism=Caenorhabditis elegans, GI71996291, Length=263, Percent_Identity=42.2053231939163, Blast_Score=220, Evalue=6e-58,
Organism=Saccharomyces cerevisiae, GI6323273, Length=255, Percent_Identity=43.5294117647059, Blast_Score=221, Evalue=1e-58,
Organism=Drosophila melanogaster, GI21355531, Length=245, Percent_Identity=43.6734693877551, Blast_Score=222, Evalue=2e-58,
Organism=Drosophila melanogaster, GI24583427, Length=260, Percent_Identity=40.3846153846154, Blast_Score=201, Evalue=4e-52,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 30296; Mature: 30296

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNYIEASSAPSKNTGAIRLYDAQAYEGMRRACQLTARCLDALADIVKPGLVTDDIDRFV
CCCEECCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
FDFGMDHGAHPATLNYRGYTKSTCTSINHVVCHGIPNDKPLREGDIVNIDVTFVLDGWHG
HHHCCCCCCCCCEEEECCCCHHHHHHCCEEEEECCCCCCCCCCCCEEEEEEEEEEECCCC
DSSRMYPVGTIKRAAERLLEVTYESLMRGISAVRPGARTGAIGEAIQTYAEAERCSVVRD
CCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
FCGHGVGRLFHDSPNILHYGRANEGPELREGMIFTIEPMINLGRPHVKVLADGWTAVTRD
HHCCCHHHHCCCCCCEEEECCCCCCCHHHCCEEEEEECHHCCCCCCEEEEECCCEEEECC
RSLSAQYEHTVGVTSDGCEIFTLSPGGLDRPGLPSLAG
CCCCCCHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MVNYIEASSAPSKNTGAIRLYDAQAYEGMRRACQLTARCLDALADIVKPGLVTDDIDRFV
CCCEECCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
FDFGMDHGAHPATLNYRGYTKSTCTSINHVVCHGIPNDKPLREGDIVNIDVTFVLDGWHG
HHHCCCCCCCCCEEEECCCCHHHHHHCCEEEEECCCCCCCCCCCCEEEEEEEEEEECCCC
DSSRMYPVGTIKRAAERLLEVTYESLMRGISAVRPGARTGAIGEAIQTYAEAERCSVVRD
CCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
FCGHGVGRLFHDSPNILHYGRANEGPELREGMIFTIEPMINLGRPHVKVLADGWTAVTRD
HHCCCHHHHCCCCCCEEEECCCCCCCHHHCCEEEEEECHHCCCCCCEEEEECCCEEEECC
RSLSAQYEHTVGVTSDGCEIFTLSPGGLDRPGLPSLAG
CCCCCCHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]