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The map label for this gene is slt [C]

Identifier: 209549062

GI number: 209549062

Start: 1486118

End: 1487074

Strand: Direct

Name: slt [C]

Synonym: Rleg2_1459

Alternate gene names: 209549062

Gene position: 1486118-1487074 (Clockwise)

Preceding gene: 209549061

Following gene: 209549063

Centisome position: 32.75

GC content: 62.17

Gene sequence:

>957_bases
ATGAGAGGGCGAAAGCGTCAGTCCGACATGGTGAGGAGATCGGCGAAGGCCCTGCTTTCGCTCTGTTTTCTGTTTTCCGT
CATCGACATGCCGAAAGCTCAGCCGGAAGGAAGCGATGCCGAGCCTGCCTGCCTCTATTTCGGGCCTTCGGCCTCGGGAT
CGAACGAGACGCTCTGTATCCGCAAGGACAGTTTCAGTCGCGATCTCTGCGCCGCAATCGAGCATTTCGCCGAGGCCAAT
CAGTTGCCGCCGGACTATTTCGCCCGCCTCATCTGGCGCGAAAGCACCTTTCGCCCCGACGCGGTCAGTTTCAAGGGGGC
GCAGGGCATCGCCCAGTTCATGCCCGGAACGGCGAAACTGCGCGGTCTCGAAGACAGCTATCAGGTGCTGGAGGCACTGC
GGAAATCGGCGCAGTATCTCGACGAATTGCGCAATCGTTTCGGTAATCTCGGTCTTGCTGCCGCCGCCTATAATGCCGGC
GAAAACGGTCTTGCCGCTTACCTTACGTCAGGAAGATTACCTTACGAGACGCGCGGCTACGTGATGGCGATTACCGCCCA
TACTGTGGAGGAATGGAAGGACAATCCGCCGGCAACGGCGGCAGCCCCGCTCGACAAGGACAAACCTTTTCTCGATGGCT
GCGTGGCGCTTGCCGAACGCCGGACGTTGAAGGACACGCCCTGGCGTCAGGAGGGCGACTGGGCGCCCTGGGGTGTCCAA
CTGGCGGCGAACGCGGATGTCGCGGTGGCCCGGCGCATGTTTCTCGATGCGGTGCAGGATCTGCCTGCGCCGCTCAATGC
GGAACAGCCGCTGATCCTGCGCCAGCGCGACCGCAGCTTCGGCTTTCGCCCGCGTTACGCAGCCCGCATCGGCCGGCAGA
CGCGCCTGGAAGCCAGCAGCCTCTGCAACCAGATCCGCAGTCACGGCGGCACCTGCCTGGTTTTCAAGAATCGATAG

Upstream 100 bases:

>100_bases
GGCTTTTTCATGCGCCATTGCCGAAATGAGGAAGCGTCGCGCCGTGATCGATGCTATCTAGGATCAGCGTCGCGATGGAA
GTCGAACCTGCCGAGATCCG

Downstream 100 bases:

>100_bases
CGTGCCGCTTTCCCATCCTTGGCGAAAACGCCGCTTGCAGGATCGCGACACGGCGCAGCATAGTCGGCGCGGATCATGCA
AAGGGAGGAACGACAATGCG

Product: Lytic transglycosylase

Products: 1,6-Anhydrobond [C]

Alternate protein names: Transglycosylase; Glycosyltransferase Protein; Transglycosylase SLT Domain-Containing Protein; Lytic Transglycosylase; SLT Domain-Containing Protein; Transglycosylase Transmembrane Protein; Glycosyltransferase

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MRGRKRQSDMVRRSAKALLSLCFLFSVIDMPKAQPEGSDAEPACLYFGPSASGSNETLCIRKDSFSRDLCAAIEHFAEAN
QLPPDYFARLIWRESTFRPDAVSFKGAQGIAQFMPGTAKLRGLEDSYQVLEALRKSAQYLDELRNRFGNLGLAAAAYNAG
ENGLAAYLTSGRLPYETRGYVMAITAHTVEEWKDNPPATAAAPLDKDKPFLDGCVALAERRTLKDTPWRQEGDWAPWGVQ
LAANADVAVARRMFLDAVQDLPAPLNAEQPLILRQRDRSFGFRPRYAARIGRQTRLEASSLCNQIRSHGGTCLVFKNR

Sequences:

>Translated_318_residues
MRGRKRQSDMVRRSAKALLSLCFLFSVIDMPKAQPEGSDAEPACLYFGPSASGSNETLCIRKDSFSRDLCAAIEHFAEAN
QLPPDYFARLIWRESTFRPDAVSFKGAQGIAQFMPGTAKLRGLEDSYQVLEALRKSAQYLDELRNRFGNLGLAAAAYNAG
ENGLAAYLTSGRLPYETRGYVMAITAHTVEEWKDNPPATAAAPLDKDKPFLDGCVALAERRTLKDTPWRQEGDWAPWGVQ
LAANADVAVARRMFLDAVQDLPAPLNAEQPLILRQRDRSFGFRPRYAARIGRQTRLEASSLCNQIRSHGGTCLVFKNR
>Mature_318_residues
MRGRKRQSDMVRRSAKALLSLCFLFSVIDMPKAQPEGSDAEPACLYFGPSASGSNETLCIRKDSFSRDLCAAIEHFAEAN
QLPPDYFARLIWRESTFRPDAVSFKGAQGIAQFMPGTAKLRGLEDSYQVLEALRKSAQYLDELRNRFGNLGLAAAAYNAG
ENGLAAYLTSGRLPYETRGYVMAITAHTVEEWKDNPPATAAAPLDKDKPFLDGCVALAERRTLKDTPWRQEGDWAPWGVQ
LAANADVAVARRMFLDAVQDLPAPLNAEQPLILRQRDRSFGFRPRYAARIGRQTRLEASSLCNQIRSHGGTCLVFKNR

Specific function: Murein-Degrading Enzyme. Catalyzes The Cleavage Of The Glycosidic Bonds Between N-Acetylmuramic Acid And N- Acetylglucosamine Residues In Peptidoglycan. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division. [C]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Periplasmic Protein. Tightly Associated With The Murein Sacculus [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 35337; Mature: 35337

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGRKRQSDMVRRSAKALLSLCFLFSVIDMPKAQPEGSDAEPACLYFGPSASGSNETLCI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCEEEE
RKDSFSRDLCAAIEHFAEANQLPPDYFARLIWRESTFRPDAVSFKGAQGIAQFMPGTAKL
ECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCHHHH
RGLEDSYQVLEALRKSAQYLDELRNRFGNLGLAAAAYNAGENGLAAYLTSGRLPYETRGY
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCE
VMAITAHTVEEWKDNPPATAAAPLDKDKPFLDGCVALAERRTLKDTPWRQEGDWAPWGVQ
EEEEEHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEE
LAANADVAVARRMFLDAVQDLPAPLNAEQPLILRQRDRSFGFRPRYAARIGRQTRLEASS
EECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCHHHHHHCCHHHHHHHH
LCNQIRSHGGTCLVFKNR
HHHHHHHCCCEEEEEECC
>Mature Secondary Structure
MRGRKRQSDMVRRSAKALLSLCFLFSVIDMPKAQPEGSDAEPACLYFGPSASGSNETLCI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCEEEE
RKDSFSRDLCAAIEHFAEANQLPPDYFARLIWRESTFRPDAVSFKGAQGIAQFMPGTAKL
ECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCHHHH
RGLEDSYQVLEALRKSAQYLDELRNRFGNLGLAAAAYNAGENGLAAYLTSGRLPYETRGY
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCE
VMAITAHTVEEWKDNPPATAAAPLDKDKPFLDGCVALAERRTLKDTPWRQEGDWAPWGVQ
EEEEEHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEE
LAANADVAVARRMFLDAVQDLPAPLNAEQPLILRQRDRSFGFRPRYAARIGRQTRLEASS
EECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCHHHHHHCCHHHHHHHH
LCNQIRSHGGTCLVFKNR
HHHHHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA