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The map label for this gene is ahpC [C]

Identifier: 209549061

GI number: 209549061

Start: 1485309

End: 1485968

Strand: Direct

Name: ahpC [C]

Synonym: Rleg2_1458

Alternate gene names: 209549061

Gene position: 1485309-1485968 (Clockwise)

Preceding gene: 209549060

Following gene: 209549062

Centisome position: 32.73

GC content: 59.09

Gene sequence:

>660_bases
ATGAGCTTACGCATCAACGATATTGCCCCCGATTTTACCGCCGACACCACTCAGGGACCGATCAGCTTCCATGACTGGAT
CGGCAATGGTTGGGCCGTCCTGTTTTCGCATCCGAAGAACTTCACGCCTGTCTGCACGACCGAGCTCGGCGCCATGGCCG
GCTTGGCGGGAGACTTTTCCAAGCGTGGCGCCAAGATCATCGGCATCTCGGTCGATCCTGTGGAAAGCCATGCCAAGTGG
AAGAACGACATCAAGACCGCCACTGGCTTCGACGTCGAATATCCGCTGATCGGCGACAAGGACCTCAAGGTCGCCAAACT
CTACGACATGCTGCCGGCCGGCGCCGGCGAGAGCTCGGAAGGCCGCACGCCCGCAGACAACGCCACCGTGCGTTCGGTTT
TCATCATTGGTCCCGATAAGAAGATCAAGCTGATCCTCACCTATCCGATGACGACGGGCCGGAATTTCAACGAGATCCTG
CGCGCCATCGATTCCATCCAGCTGACGGCCAAGCACCAGGTGGCGACACCGGCGAACTGGAACCAGGGCGATGACGTCAT
CATCACCGCCGCGGTTTCCAACGAAGACGCGATCACGCGTTTCGGCTCCTTCGATACGGTTCTGCCTTATCTCCGGAAGA
CCAAACAGCCGACAGCCTGA

Upstream 100 bases:

>100_bases
ACCCTGAAGACCGCAATCCAGCGACCGCTTCCGGCGGACGGATCCCATGGCCTCGATTTGAGATGCTCAAGAATTAACAC
AAGGCTTTGGAGGGCCGACC

Downstream 100 bases:

>100_bases
TCGCTGCTTTCAAGCCCGTTTACGAAGCCGCCGCGGCCATTGGCCCGGCGGCTTTTTCATGCGCCATTGCCGAAATGAGG
AAGCGTCGCGCCGTGATCGA

Product: Peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MSLRINDIAPDFTADTTQGPISFHDWIGNGWAVLFSHPKNFTPVCTTELGAMAGLAGDFSKRGAKIIGISVDPVESHAKW
KNDIKTATGFDVEYPLIGDKDLKVAKLYDMLPAGAGESSEGRTPADNATVRSVFIIGPDKKIKLILTYPMTTGRNFNEIL
RAIDSIQLTAKHQVATPANWNQGDDVIITAAVSNEDAITRFGSFDTVLPYLRKTKQPTA

Sequences:

>Translated_219_residues
MSLRINDIAPDFTADTTQGPISFHDWIGNGWAVLFSHPKNFTPVCTTELGAMAGLAGDFSKRGAKIIGISVDPVESHAKW
KNDIKTATGFDVEYPLIGDKDLKVAKLYDMLPAGAGESSEGRTPADNATVRSVFIIGPDKKIKLILTYPMTTGRNFNEIL
RAIDSIQLTAKHQVATPANWNQGDDVIITAAVSNEDAITRFGSFDTVLPYLRKTKQPTA
>Mature_218_residues
SLRINDIAPDFTADTTQGPISFHDWIGNGWAVLFSHPKNFTPVCTTELGAMAGLAGDFSKRGAKIIGISVDPVESHAKWK
NDIKTATGFDVEYPLIGDKDLKVAKLYDMLPAGAGESSEGRTPADNATVRSVFIIGPDKKIKLILTYPMTTGRNFNEILR
AIDSIQLTAKHQVATPANWNQGDDVIITAAVSNEDAITRFGSFDTVLPYLRKTKQPTA

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=225, Percent_Identity=46.6666666666667, Blast_Score=200, Evalue=7e-52,
Organism=Homo sapiens, GI32189392, Length=189, Percent_Identity=31.2169312169312, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI4505591, Length=190, Percent_Identity=32.6315789473684, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI32455266, Length=190, Percent_Identity=32.6315789473684, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI32455264, Length=190, Percent_Identity=32.6315789473684, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI5802974, Length=161, Percent_Identity=29.8136645962733, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI32483377, Length=161, Percent_Identity=29.8136645962733, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI5453549, Length=159, Percent_Identity=28.3018867924528, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1786822, Length=155, Percent_Identity=29.6774193548387, Blast_Score=71, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI25153706, Length=209, Percent_Identity=38.755980861244, Blast_Score=154, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17554494, Length=181, Percent_Identity=28.1767955801105, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI32565831, Length=168, Percent_Identity=29.1666666666667, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI193204376, Length=168, Percent_Identity=29.1666666666667, Blast_Score=84, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6319407, Length=214, Percent_Identity=54.6728971962617, Blast_Score=226, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6320661, Length=188, Percent_Identity=29.7872340425532, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323613, Length=188, Percent_Identity=28.1914893617021, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24652434, Length=224, Percent_Identity=45.9821428571429, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI17975518, Length=212, Percent_Identity=47.1698113207547, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24652436, Length=224, Percent_Identity=45.5357142857143, Blast_Score=188, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24581278, Length=225, Percent_Identity=45.7777777777778, Blast_Score=186, Evalue=7e-48,
Organism=Drosophila melanogaster, GI17738015, Length=185, Percent_Identity=31.3513513513514, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21357347, Length=199, Percent_Identity=27.6381909547739, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17157991, Length=169, Percent_Identity=31.3609467455621, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24641739, Length=169, Percent_Identity=31.3609467455621, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24656348, Length=169, Percent_Identity=29.585798816568, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI17864676, Length=169, Percent_Identity=29.585798816568, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23780; Mature: 23649

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRINDIAPDFTADTTQGPISFHDWIGNGWAVLFSHPKNFTPVCTTELGAMAGLAGDFS
CCEECCCCCCCCCCCCCCCCCCHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCHH
KRGAKIIGISVDPVESHAKWKNDIKTATGFDVEYPLIGDKDLKVAKLYDMLPAGAGESSE
HCCCEEEEEECCCCHHHHHHHHHCCCCCCCCEECCCCCCCCCHHHHHHHHHCCCCCCCCC
GRTPADNATVRSVFIIGPDKKIKLILTYPMTTGRNFNEILRAIDSIQLTAKHQVATPANW
CCCCCCCCEEEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHEEEEECCCCCCCCCC
NQGDDVIITAAVSNEDAITRFGSFDTVLPYLRKTKQPTA
CCCCCEEEEEEECCCCHHHHCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SLRINDIAPDFTADTTQGPISFHDWIGNGWAVLFSHPKNFTPVCTTELGAMAGLAGDFS
CEECCCCCCCCCCCCCCCCCCHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCHH
KRGAKIIGISVDPVESHAKWKNDIKTATGFDVEYPLIGDKDLKVAKLYDMLPAGAGESSE
HCCCEEEEEECCCCHHHHHHHHHCCCCCCCCEECCCCCCCCCHHHHHHHHHCCCCCCCCC
GRTPADNATVRSVFIIGPDKKIKLILTYPMTTGRNFNEILRAIDSIQLTAKHQVATPANW
CCCCCCCCEEEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHEEEEECCCCCCCCCC
NQGDDVIITAAVSNEDAITRFGSFDTVLPYLRKTKQPTA
CCCCCEEEEEEECCCCHHHHCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA