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The map label for this gene is lrp [H]

Identifier: 209549008

GI number: 209549008

Start: 1425578

End: 1426078

Strand: Reverse

Name: lrp [H]

Synonym: Rleg2_1405

Alternate gene names: 209549008

Gene position: 1426078-1425578 (Counterclockwise)

Preceding gene: 209549013

Following gene: 209549006

Centisome position: 31.43

GC content: 58.88

Gene sequence:

>501_bases
ATGGATGAACAGCTCGACAAATTGGATTTGCGCCTGCTCGAGGAACTGCAAAAGGACGGCAGGTTGACGAATAACGAGCT
GGGCGATCGCATCGCGCTTTCACCCTCGCAATGCTCGCGCCGGCGCACGCGGCTGGAGGCCGAGGGCTATATTCGCAGCT
ACCGGGCCTATCTCGATCGGGAGAAGCTGGGCCTGGATATGCTGGTGGTCATTTCCGTGACGCTTGCGACCCACAATAGA
GACAATGCCCGCCGATTTTCCCAGTTGATCAACGGGTTGCCGGAAGTTCTCGAAGCCTATGCTTTGACGGGGGAAATGGA
CTACCACCTGAAGGTGGCGGCCCGCGGCCTCGCCGACCTTTCAAAATTCGTCAACGACGTTCTCTTGCCGCACGAGTCGG
TCCAGCACGTGAAGACCTCGATCGTGCTCGACACGCTGAAGACATTCGAGGGCTTTCCCGTGCACATGCCGGGCAGCCGG
CATGGCGACAGCATGCGATAA

Upstream 100 bases:

>100_bases
TGCGCAAAGTGTGGCGCAAAACACGTGCAAAATCCTTGCATTCTTCATGCTTGGAGAAGATATTATGCACGGTTCGTGAG
CATTCTGGAGATTTCGTGCA

Downstream 100 bases:

>100_bases
ATTTAAGAACATCCCTGCCCCGCCGGCGGCAGGCGTCAGAGCGGCAATTCGGTCGAGAATTTCAGTTCGCGCAGCACGAA
GCTCGAGACAACTGTGCGCA

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MDEQLDKLDLRLLEELQKDGRLTNNELGDRIALSPSQCSRRRTRLEAEGYIRSYRAYLDREKLGLDMLVVISVTLATHNR
DNARRFSQLINGLPEVLEAYALTGEMDYHLKVAARGLADLSKFVNDVLLPHESVQHVKTSIVLDTLKTFEGFPVHMPGSR
HGDSMR

Sequences:

>Translated_166_residues
MDEQLDKLDLRLLEELQKDGRLTNNELGDRIALSPSQCSRRRTRLEAEGYIRSYRAYLDREKLGLDMLVVISVTLATHNR
DNARRFSQLINGLPEVLEAYALTGEMDYHLKVAARGLADLSKFVNDVLLPHESVQHVKTSIVLDTLKTFEGFPVHMPGSR
HGDSMR
>Mature_166_residues
MDEQLDKLDLRLLEELQKDGRLTNNELGDRIALSPSQCSRRRTRLEAEGYIRSYRAYLDREKLGLDMLVVISVTLATHNR
DNARRFSQLINGLPEVLEAYALTGEMDYHLKVAARGLADLSKFVNDVLLPHESVQHVKTSIVLDTLKTFEGFPVHMPGSR
HGDSMR

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=143, Percent_Identity=34.965034965035, Blast_Score=94, Evalue=5e-21,
Organism=Escherichia coli, GI87081742, Length=151, Percent_Identity=27.8145695364238, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 18904; Mature: 18904

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEQLDKLDLRLLEELQKDGRLTNNELGDRIALSPSQCSRRRTRLEAEGYIRSYRAYLDR
CCCHHHHHHHHHHHHHHHCCCCCCHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EKLGLDMLVVISVTLATHNRDNARRFSQLINGLPEVLEAYALTGEMDYHLKVAARGLADL
HHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
SKFVNDVLLPHESVQHVKTSIVLDTLKTFEGFPVHMPGSRHGDSMR
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDEQLDKLDLRLLEELQKDGRLTNNELGDRIALSPSQCSRRRTRLEAEGYIRSYRAYLDR
CCCHHHHHHHHHHHHHHHCCCCCCHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EKLGLDMLVVISVTLATHNRDNARRFSQLINGLPEVLEAYALTGEMDYHLKVAARGLADL
HHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
SKFVNDVLLPHESVQHVKTSIVLDTLKTFEGFPVHMPGSRHGDSMR
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11157937; 11481430 [H]