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The map label for this gene is degU [H]

Identifier: 209548992

GI number: 209548992

Start: 1411811

End: 1412431

Strand: Reverse

Name: degU [H]

Synonym: Rleg2_1389

Alternate gene names: 209548992

Gene position: 1412431-1411811 (Counterclockwise)

Preceding gene: 209548993

Following gene: 209548990

Centisome position: 31.12

GC content: 59.42

Gene sequence:

>621_bases
ATGACATCCATCACGATCGGCGTCGTGGACGACCATCCGCTTTTTCGCGAGGGCGTAACCCGGAGCCTCTCCGAGATCAG
CGACTTTGCCGTCGTTGGGGAAGGCGCCAGCAGCGATGACGCTGCGATGATCGCTGCGAACAATCATCCCGACATCATGC
TCCTCGATGTCTCGATGCCCGGCGGCGGGCTGTCGGCGATCAGCGACGTGCTGACGCGGAGCCCGGCAACGAAAGTGCTG
ATGTTGACGGTATCCGAGGAGGTGGACACGCTGATGGCAGCCCTGCAACGGGGCGCAATGGGCTATGTTCTCAAAGGTGT
CGGCTCGCGCGGTCTCGCCGAAGCCATCCAGACTGTGCTGAGCGGATCACGCTACATCTCCCCGACAATGTCGACAAAGG
TCATGGAGAATTCGCTGAATGGCGGCGCCACCGAGAAGAACGGTCTGACGCCACGGGAACGCGAGGTGATGGATCTCGTC
GCTCAAGGCTTGTCAAACAAGCATATCGGCTTGCGTCTCAGCCTGCAGGAAAAGACGGTGAAGCATCATATGACACAGAT
TTTGAGCAAGCTCGGCGTCTCGAACAGGACTGAAGCGGCTCTGCAATGGCGCCAACACTAG

Upstream 100 bases:

>100_bases
AACGGATCGACAGTCTGGGAGGATCCTTCGACGTGAAGACGGGCGAAGGAGGGACGACGGTGACCATGACCTTCGAGCCT
ATGGAAGTGGGAGATTAGAC

Downstream 100 bases:

>100_bases
ATCAGTTGACCACATCCCCGCTTTAGGTTTTTTAGCGGAGGTAGCGGCCTAGCCGGCGGGCATCGTTTGCCGTCGCTTGC
CGGCTTATGATCGTCCTGCC

Product: LuxR family transcriptional regulator

Products: NA

Alternate protein names: Protease production enhancer protein [H]

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MTSITIGVVDDHPLFREGVTRSLSEISDFAVVGEGASSDDAAMIAANNHPDIMLLDVSMPGGGLSAISDVLTRSPATKVL
MLTVSEEVDTLMAALQRGAMGYVLKGVGSRGLAEAIQTVLSGSRYISPTMSTKVMENSLNGGATEKNGLTPREREVMDLV
AQGLSNKHIGLRLSLQEKTVKHHMTQILSKLGVSNRTEAALQWRQH

Sequences:

>Translated_206_residues
MTSITIGVVDDHPLFREGVTRSLSEISDFAVVGEGASSDDAAMIAANNHPDIMLLDVSMPGGGLSAISDVLTRSPATKVL
MLTVSEEVDTLMAALQRGAMGYVLKGVGSRGLAEAIQTVLSGSRYISPTMSTKVMENSLNGGATEKNGLTPREREVMDLV
AQGLSNKHIGLRLSLQEKTVKHHMTQILSKLGVSNRTEAALQWRQH
>Mature_205_residues
TSITIGVVDDHPLFREGVTRSLSEISDFAVVGEGASSDDAAMIAANNHPDIMLLDVSMPGGGLSAISDVLTRSPATKVLM
LTVSEEVDTLMAALQRGAMGYVLKGVGSRGLAEAIQTVLSGSRYISPTMSTKVMENSLNGGATEKNGLTPREREVMDLVA
QGLSNKHIGLRLSLQEKTVKHHMTQILSKLGVSNRTEAALQWRQH

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=198, Percent_Identity=33.8383838383838, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1787473, Length=204, Percent_Identity=38.2352941176471, Blast_Score=110, Evalue=5e-26,
Organism=Escherichia coli, GI1788521, Length=211, Percent_Identity=35.0710900473934, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790102, Length=198, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788546, Length=203, Percent_Identity=30.0492610837438, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786747, Length=202, Percent_Identity=26.7326732673267, Blast_Score=75, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 21970; Mature: 21838

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSITIGVVDDHPLFREGVTRSLSEISDFAVVGEGASSDDAAMIAANNHPDIMLLDVSMP
CCEEEEEEECCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEEECCCCCEEEEEECCC
GGGLSAISDVLTRSPATKVLMLTVSEEVDTLMAALQRGAMGYVLKGVGSRGLAEAIQTVL
CCCHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHH
SGSRYISPTMSTKVMENSLNGGATEKNGLTPREREVMDLVAQGLSNKHIGLRLSLQEKTV
CCCCEECCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHHH
KHHMTQILSKLGVSNRTEAALQWRQH
HHHHHHHHHHHCCCCCHHHHHHHCCC
>Mature Secondary Structure 
TSITIGVVDDHPLFREGVTRSLSEISDFAVVGEGASSDDAAMIAANNHPDIMLLDVSMP
CEEEEEEECCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEEECCCCCEEEEEECCC
GGGLSAISDVLTRSPATKVLMLTVSEEVDTLMAALQRGAMGYVLKGVGSRGLAEAIQTVL
CCCHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHH
SGSRYISPTMSTKVMENSLNGGATEKNGLTPREREVMDLVAQGLSNKHIGLRLSLQEKTV
CCCCEECCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHHH
KHHMTQILSKLGVSNRTEAALQWRQH
HHHHHHHHHHHCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3136143; 3141378; 3141377; 9384377 [H]