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The map label for this gene is degQ [H]

Identifier: 209548967

GI number: 209548967

Start: 1382683

End: 1384086

Strand: Direct

Name: degQ [H]

Synonym: Rleg2_1364

Alternate gene names: 209548967

Gene position: 1382683-1384086 (Clockwise)

Preceding gene: 209548964

Following gene: 209548968

Centisome position: 30.47

GC content: 63.39

Gene sequence:

>1404_bases
ATGCAAGGCCTGTTCAAACACGCCTCCGTTTCGCTGCTCGCTCTGACGCTGCTTCTGCCGGCTGCCGCTTACGCGCAGAC
GGCAAAGACGGTGCCCGAGAGCCAGATGCAGATGCAGCTCTCCTTCGCGCCGCTCGTCAAGCAGACATCCGGCGCCGTCG
TCAATGTCTATGCGGAAAAGACCGTCCAGCGGCAGTCGCCCTTTGCCGGCGATCCCTTCTTCGAGCAGTTTTTCGGCCAG
CAGATGCCGAATCGCTCGGAAAAGCAGTCCTCGCTCGGTTCCGGCGTCATCGTCGAGGCGAACGGCACTGTCGTGACCAA
CAATCACGTGGTCGAAGGCGCCGACGATATCAAGGTTGCGCTGCCTGATGGACGCGAGTTCCCCTGCAAAGTGGTGCTGC
GCGACGACCGCGTCGATCTTGCCGTGCTGAAGATCGACACCAAGGAAAGCTTCCCGACATTGCCGATCGGCAATTCCGAT
GCCGTCGAGGTCGGTGATCTCGTGCTGGCGATCGGCAACCCCTTCGGCGTCGGCCAGACGGTGACGAGCGGTATCGTCTC
CGCGCTTGCCCGCAACCAGGTGGTCAGGAACGAGTTCGGCTTCTTCATCCAGACCGACGCCTCGATCAATCCCGGCAATT
CCGGCGGCGCCCTGATGAACATGAAGGGCGAACTGATCGGCATCAATACGGCGATCTTCTCGCGCGGCGGCGGCTCGAAC
GGTATCGGCTTTGCCATCCCCGCCAATCTGGTCAAGGTCTTCCTCGCTTCGGCCGATGCCGGCGTCAAATCCTTCGAGCG
GCCCTATGTCGGCGCGAGTTTCGATGCGGTGACCTCGGAAGTCGCCGAAGCGCTTGGACTGAATAAGGCGCGCGGCGCAC
TGGTGGTCAAGGTTTCGGAAGGCGGCCCGGCCGCCAAGGCCGGGCTGAAGGCAGGTGAAATCGTCACCGCTGTCGACGGT
ATTTCGGTCGAGCATCCGGATGCGCTGCTTTACCGGCTGACGACGGCCGGTCTCGGAAAATCGGTCAAGCTCACGGTCGT
CGAGAACGGCCGCGAGGAGCAGCTGCCGCTGACGCTCGATCGCGCCCCGGAAACCTCGCCGCGCGACCAGCGCACCATCG
GCGGGCGTACTCCCTTCAGCGGTGCTGTCGTCGAGAACCTGTCGCCGCGGGTCGCCGACGAGTTGCGCATGCCGCCGGAA
TCGGCAGGCGTCGTCGTATCTGAGGTGAAGGAGGATTCGCCTGCCGCCCGTCTCGGTTTCGAGCCGAAGGATATCATCGT
CTCGATCAACGGCACCGATGTGAAGTCGACCAGCGAGCTGTCCCAAATCGCCGATAGCGACCCCGGCCTCTGGCGGGTGG
AAATCGAGCGCGACGGCCAGCGCATCCGGCAGTTCTTCCGATGA

Upstream 100 bases:

>100_bases
CGCAACTAAATAGTTAGAGCATGATGTCGTCCGAAAACCGCTCACACTTTTCGGCATCATGCTCTAAACGTTGCTCAAGA
GGATTCAAAAAGGGATAATC

Downstream 100 bases:

>100_bases
GCAATGATCTCTTCGCGCCGCGCGTTCCGGAGGAGGTTGCCGCCAGGCGGCCGCTTGCCGACCGGCTGCGGCCGAAGACG
CTTGCCGATGTCACCGGTCA

Product: protease Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MQGLFKHASVSLLALTLLLPAAAYAQTAKTVPESQMQMQLSFAPLVKQTSGAVVNVYAEKTVQRQSPFAGDPFFEQFFGQ
QMPNRSEKQSSLGSGVIVEANGTVVTNNHVVEGADDIKVALPDGREFPCKVVLRDDRVDLAVLKIDTKESFPTLPIGNSD
AVEVGDLVLAIGNPFGVGQTVTSGIVSALARNQVVRNEFGFFIQTDASINPGNSGGALMNMKGELIGINTAIFSRGGGSN
GIGFAIPANLVKVFLASADAGVKSFERPYVGASFDAVTSEVAEALGLNKARGALVVKVSEGGPAAKAGLKAGEIVTAVDG
ISVEHPDALLYRLTTAGLGKSVKLTVVENGREEQLPLTLDRAPETSPRDQRTIGGRTPFSGAVVENLSPRVADELRMPPE
SAGVVVSEVKEDSPAARLGFEPKDIIVSINGTDVKSTSELSQIADSDPGLWRVEIERDGQRIRQFFR

Sequences:

>Translated_467_residues
MQGLFKHASVSLLALTLLLPAAAYAQTAKTVPESQMQMQLSFAPLVKQTSGAVVNVYAEKTVQRQSPFAGDPFFEQFFGQ
QMPNRSEKQSSLGSGVIVEANGTVVTNNHVVEGADDIKVALPDGREFPCKVVLRDDRVDLAVLKIDTKESFPTLPIGNSD
AVEVGDLVLAIGNPFGVGQTVTSGIVSALARNQVVRNEFGFFIQTDASINPGNSGGALMNMKGELIGINTAIFSRGGGSN
GIGFAIPANLVKVFLASADAGVKSFERPYVGASFDAVTSEVAEALGLNKARGALVVKVSEGGPAAKAGLKAGEIVTAVDG
ISVEHPDALLYRLTTAGLGKSVKLTVVENGREEQLPLTLDRAPETSPRDQRTIGGRTPFSGAVVENLSPRVADELRMPPE
SAGVVVSEVKEDSPAARLGFEPKDIIVSINGTDVKSTSELSQIADSDPGLWRVEIERDGQRIRQFFR
>Mature_467_residues
MQGLFKHASVSLLALTLLLPAAAYAQTAKTVPESQMQMQLSFAPLVKQTSGAVVNVYAEKTVQRQSPFAGDPFFEQFFGQ
QMPNRSEKQSSLGSGVIVEANGTVVTNNHVVEGADDIKVALPDGREFPCKVVLRDDRVDLAVLKIDTKESFPTLPIGNSD
AVEVGDLVLAIGNPFGVGQTVTSGIVSALARNQVVRNEFGFFIQTDASINPGNSGGALMNMKGELIGINTAIFSRGGGSN
GIGFAIPANLVKVFLASADAGVKSFERPYVGASFDAVTSEVAEALGLNKARGALVVKVSEGGPAAKAGLKAGEIVTAVDG
ISVEHPDALLYRLTTAGLGKSVKLTVVENGREEQLPLTLDRAPETSPRDQRTIGGRTPFSGAVVENLSPRVADELRMPPE
SAGVVVSEVKEDSPAARLGFEPKDIIVSINGTDVKSTSELSQIADSDPGLWRVEIERDGQRIRQFFR

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=245, Percent_Identity=37.9591836734694, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI7019477, Length=307, Percent_Identity=34.5276872964169, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI22129776, Length=323, Percent_Identity=30.9597523219814, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI24308541, Length=244, Percent_Identity=34.8360655737705, Blast_Score=132, Evalue=6e-31,
Organism=Escherichia coli, GI1789629, Length=464, Percent_Identity=37.7155172413793, Blast_Score=269, Evalue=3e-73,
Organism=Escherichia coli, GI1786356, Length=457, Percent_Identity=38.074398249453, Blast_Score=268, Evalue=6e-73,
Organism=Escherichia coli, GI1789630, Length=372, Percent_Identity=33.6021505376344, Blast_Score=174, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24646839, Length=266, Percent_Identity=34.9624060150376, Blast_Score=133, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 49345; Mature: 49345

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGLFKHASVSLLALTLLLPAAAYAQTAKTVPESQMQMQLSFAPLVKQTSGAVVNVYAEK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEHHHHHHHCCCCCEEEEEEHH
TVQRQSPFAGDPFFEQFFGQQMPNRSEKQSSLGSGVIVEANGTVVTNNHVVEGADDIKVA
HHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHCCCCEEEECCCEEEECCEEEECCCCEEEE
LPDGREFPCKVVLRDDRVDLAVLKIDTKESFPTLPIGNSDAVEVGDLVLAIGNPFGVGQT
CCCCCCCCEEEEEECCCEEEEEEEEECCCCCCCCCCCCCCCEEECEEEEEECCCCCCCHH
VTSGIVSALARNQVVRNEFGFFIQTDASINPGNSGGALMNMKGELIGINTAIFSRGGGSN
HHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEECCCEEEEEHHEEECCCCCC
GIGFAIPANLVKVFLASADAGVKSFERPYVGASFDAVTSEVAEALGLNKARGALVVKVSE
CCEEECHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECC
GGPAAKAGLKAGEIVTAVDGISVEHPDALLYRLTTAGLGKSVKLTVVENGREEQLPLTLD
CCCHHHHCCCCCCEEEEECCCCCCCCCCEEEEEHHCCCCCEEEEEEEECCCCCCCCEEEC
RAPETSPRDQRTIGGRTPFSGAVVENLSPRVADELRMPPESAGVVVSEVKEDSPAARLGF
CCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHCCCCCCCCEEEEECCCCCCHHHCCC
EPKDIIVSINGTDVKSTSELSQIADSDPGLWRVEIERDGQRIRQFFR
CCCCEEEEECCCCCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHC
>Mature Secondary Structure
MQGLFKHASVSLLALTLLLPAAAYAQTAKTVPESQMQMQLSFAPLVKQTSGAVVNVYAEK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEHHHHHHHCCCCCEEEEEEHH
TVQRQSPFAGDPFFEQFFGQQMPNRSEKQSSLGSGVIVEANGTVVTNNHVVEGADDIKVA
HHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHCCCCEEEECCCEEEECCEEEECCCCEEEE
LPDGREFPCKVVLRDDRVDLAVLKIDTKESFPTLPIGNSDAVEVGDLVLAIGNPFGVGQT
CCCCCCCCEEEEEECCCEEEEEEEEECCCCCCCCCCCCCCCEEECEEEEEECCCCCCCHH
VTSGIVSALARNQVVRNEFGFFIQTDASINPGNSGGALMNMKGELIGINTAIFSRGGGSN
HHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEECCCEEEEEHHEEECCCCCC
GIGFAIPANLVKVFLASADAGVKSFERPYVGASFDAVTSEVAEALGLNKARGALVVKVSE
CCEEECHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECC
GGPAAKAGLKAGEIVTAVDGISVEHPDALLYRLTTAGLGKSVKLTVVENGREEQLPLTLD
CCCHHHHCCCCCCEEEEECCCCCCCCCCEEEEEHHCCCCCEEEEEEEECCCCCCCCEEEC
RAPETSPRDQRTIGGRTPFSGAVVENLSPRVADELRMPPESAGVVVSEVKEDSPAARLGF
CCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHCCCCCCCCEEEEECCCCCCHHHCCC
EPKDIIVSINGTDVKSTSELSQIADSDPGLWRVEIERDGQRIRQFFR
CCCCEEEEECCCCCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]