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The map label for this gene is lolC [H]

Identifier: 209548883

GI number: 209548883

Start: 1298273

End: 1299577

Strand: Direct

Name: lolC [H]

Synonym: Rleg2_1280

Alternate gene names: 209548883

Gene position: 1298273-1299577 (Clockwise)

Preceding gene: 209548882

Following gene: 209548884

Centisome position: 28.61

GC content: 61.84

Gene sequence:

>1305_bases
ATGGCAGAGGCAGCAGTGGACCGGAGTTCGAAATCCGGCTTGGGTCCGGCTGGCAAGCCATTTTCCACCTTCGAACGCCT
CGTGGCGTGGCGCTATCTGCGCGCCCGCCGCAAGGAAGCCTTCATTTCGGTGATCGCCGGCTTCTCCTTCGTCGGCATCA
TGCTCGGCGTTGCGACGCTGATCATCGTCATGGCCGTCATGAACGGCTTCCGCACCGAGCTCGTCTCACGCATCCTCGGC
ATCAACGGCCATATGATCGTCCAGCCGTCCGATGGCCCCTTCACCGATTATGCCGACCTCTCCAGCAGGCTTGCCGCCGT
GCCGGGCGTCAAGATGGCGCTGCCCTTGGTGGAAGGCCAGGTGCTTGCCTCTGCCCAGGCTGGCGGCAGCACCGGTGCGC
TGGTGCGCGGCGCCCGCGCCGAGGACCTGACCAAGCTCAAGACGATCTCCGGCAACATCAAATCAGGCGACATGGTGGGT
TTTGCCTCCGGCCAGGGCGTGCTGATCGGCACCGGCATGGCCAACCAGCTCGGCCTGAGCGTCGGCGACCTCATCACGCT
GACGTCGCCGGATGGTGACATTACGCCGATGGGCGTCAGCCCGCGCGTCAAGTCCTACAAGATCTCCGGTCTCTTCGAGA
TCGGCATGTCGGAATATGATTCCTCGATCATCTTCATGCCGCTCGAGGAAGCGCAGCTGTATTTCAATGCCGAGGGACTG
GTGCAGTCGATAGAGCTTTTCGTCGATCACCCCGATGATATCGACACTCTGCGGCCCAAGGTGGAGGAAGCGGCTGGCCG
CCAGATCAACCTCACCGACTGGCGCCAGCGCAACCAGACCTTCTTTTCGGCGCTGCAGGTCGAGCGCAACGTCATGTTCA
TGATCCTGACGCTGATCGTGCTTGTCGCAGCTCTGAACATCATCTCCGGCCTGATCATGCTGGTGAAGGACAAGAGCAGC
GATATCGCCATTCTGCGCACCATGGGCGCCAGCGCCGGCGCGATCATGCGCATCTTCTTCATGACCGGGGCGGCGATCGG
GATCGTCGGCACTGTTGCCGGCGTGCTGCTCGGCGTCCTCGTCTGCGTCAACATCGAATCCATCCGCCAGTTCTTCTCCT
GGATTTCAGGCACGGTGATCTTCAATCCGCAGGTCTATTTTCTCAGTCAGCTGCCGGCCGAGATGCAGCTCAGCGAAACG
ATCTCGATCGTCGTCATGGCGCTGACGCTCTCCTTCATCGCGACCATCTTTCCGGCCTGGCGCGCCTCCAGGCTCGATCC
GGTGCAGGCCCTGCGCTACGAATAA

Upstream 100 bases:

>100_bases
CGGCGAAGTCGAGGTGAAGGACCGCAAGACCGGCGCCCGCGAAACGATGACCATCGAAGCGGCGATCAACAGGTTCGTGG
CTTAAGGAAACGGAGGCGAA

Downstream 100 bases:

>100_bases
GGAATGCCGCCTTCATGAAACGCAACGTCGTTCTCAATCTTACCGGCGTCGAGCGCCATTACGGGCAGGGCGATACGCTG
CTGCCGATCCTGAAGGGCGC

Product: lipoprotein releasing system, transmembrane protein, LolC/E family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MAEAAVDRSSKSGLGPAGKPFSTFERLVAWRYLRARRKEAFISVIAGFSFVGIMLGVATLIIVMAVMNGFRTELVSRILG
INGHMIVQPSDGPFTDYADLSSRLAAVPGVKMALPLVEGQVLASAQAGGSTGALVRGARAEDLTKLKTISGNIKSGDMVG
FASGQGVLIGTGMANQLGLSVGDLITLTSPDGDITPMGVSPRVKSYKISGLFEIGMSEYDSSIIFMPLEEAQLYFNAEGL
VQSIELFVDHPDDIDTLRPKVEEAAGRQINLTDWRQRNQTFFSALQVERNVMFMILTLIVLVAALNIISGLIMLVKDKSS
DIAILRTMGASAGAIMRIFFMTGAAIGIVGTVAGVLLGVLVCVNIESIRQFFSWISGTVIFNPQVYFLSQLPAEMQLSET
ISIVVMALTLSFIATIFPAWRASRLDPVQALRYE

Sequences:

>Translated_434_residues
MAEAAVDRSSKSGLGPAGKPFSTFERLVAWRYLRARRKEAFISVIAGFSFVGIMLGVATLIIVMAVMNGFRTELVSRILG
INGHMIVQPSDGPFTDYADLSSRLAAVPGVKMALPLVEGQVLASAQAGGSTGALVRGARAEDLTKLKTISGNIKSGDMVG
FASGQGVLIGTGMANQLGLSVGDLITLTSPDGDITPMGVSPRVKSYKISGLFEIGMSEYDSSIIFMPLEEAQLYFNAEGL
VQSIELFVDHPDDIDTLRPKVEEAAGRQINLTDWRQRNQTFFSALQVERNVMFMILTLIVLVAALNIISGLIMLVKDKSS
DIAILRTMGASAGAIMRIFFMTGAAIGIVGTVAGVLLGVLVCVNIESIRQFFSWISGTVIFNPQVYFLSQLPAEMQLSET
ISIVVMALTLSFIATIFPAWRASRLDPVQALRYE
>Mature_433_residues
AEAAVDRSSKSGLGPAGKPFSTFERLVAWRYLRARRKEAFISVIAGFSFVGIMLGVATLIIVMAVMNGFRTELVSRILGI
NGHMIVQPSDGPFTDYADLSSRLAAVPGVKMALPLVEGQVLASAQAGGSTGALVRGARAEDLTKLKTISGNIKSGDMVGF
ASGQGVLIGTGMANQLGLSVGDLITLTSPDGDITPMGVSPRVKSYKISGLFEIGMSEYDSSIIFMPLEEAQLYFNAEGLV
QSIELFVDHPDDIDTLRPKVEEAAGRQINLTDWRQRNQTFFSALQVERNVMFMILTLIVLVAALNIISGLIMLVKDKSSD
IAILRTMGASAGAIMRIFFMTGAAIGIVGTVAGVLLGVLVCVNIESIRQFFSWISGTVIFNPQVYFLSQLPAEMQLSETI
SIVVMALTLSFIATIFPAWRASRLDPVQALRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=407, Percent_Identity=30.2211302211302, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI1787360, Length=421, Percent_Identity=30.6413301662708, Blast_Score=164, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46661; Mature: 46530

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEAAVDRSSKSGLGPAGKPFSTFERLVAWRYLRARRKEAFISVIAGFSFVGIMLGVATL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIVMAVMNGFRTELVSRILGINGHMIVQPSDGPFTDYADLSSRLAAVPGVKMALPLVEGQ
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCH
VLASAQAGGSTGALVRGARAEDLTKLKTISGNIKSGDMVGFASGQGVLIGTGMANQLGLS
HHHHCCCCCCCCHHEECCCHHHHHHHHHHCCCCCCCCEEEEECCCEEEEECCCCHHHCCC
VGDLITLTSPDGDITPMGVSPRVKSYKISGLFEIGMSEYDSSIIFMPLEEAQLYFNAEGL
CCCEEEEECCCCCEECCCCCCCCCCEEECHHHHHCHHHCCCCEEEEEEHHHHEEECHHHH
VQSIELFVDHPDDIDTLRPKVEEAAGRQINLTDWRQRNQTFFSALQVERNVMFMILTLIV
HHHHHHHCCCCCCHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVAALNIISGLIMLVKDKSSDIAILRTMGASAGAIMRIFFMTGAAIGIVGTVAGVLLGVL
HHHHHHHHHHHHEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VCVNIESIRQFFSWISGTVIFNPQVYFLSQLPAEMQLSETISIVVMALTLSFIATIFPAW
HHHCHHHHHHHHHHHCCEEEECCCEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RASRLDPVQALRYE
HCCCCCHHHHHCCC
>Mature Secondary Structure 
AEAAVDRSSKSGLGPAGKPFSTFERLVAWRYLRARRKEAFISVIAGFSFVGIMLGVATL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIVMAVMNGFRTELVSRILGINGHMIVQPSDGPFTDYADLSSRLAAVPGVKMALPLVEGQ
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCH
VLASAQAGGSTGALVRGARAEDLTKLKTISGNIKSGDMVGFASGQGVLIGTGMANQLGLS
HHHHCCCCCCCCHHEECCCHHHHHHHHHHCCCCCCCCEEEEECCCEEEEECCCCHHHCCC
VGDLITLTSPDGDITPMGVSPRVKSYKISGLFEIGMSEYDSSIIFMPLEEAQLYFNAEGL
CCCEEEEECCCCCEECCCCCCCCCCEEECHHHHHCHHHCCCCEEEEEEHHHHEEECHHHH
VQSIELFVDHPDDIDTLRPKVEEAAGRQINLTDWRQRNQTFFSALQVERNVMFMILTLIV
HHHHHHHCCCCCCHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVAALNIISGLIMLVKDKSSDIAILRTMGASAGAIMRIFFMTGAAIGIVGTVAGVLLGVL
HHHHHHHHHHHHEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VCVNIESIRQFFSWISGTVIFNPQVYFLSQLPAEMQLSETISIVVMALTLSFIATIFPAW
HHHCHHHHHHHHHHHCCEEEECCCEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RASRLDPVQALRYE
HCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]