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The map label for this gene is 209548879

Identifier: 209548879

GI number: 209548879

Start: 1293850

End: 1295520

Strand: Direct

Name: 209548879

Synonym: Rleg2_1276

Alternate gene names: NA

Gene position: 1293850-1295520 (Clockwise)

Preceding gene: 209548878

Following gene: 209548880

Centisome position: 28.51

GC content: 63.26

Gene sequence:

>1671_bases
ATGGCGAAACAGGACGAGTTGGTATTCCTGCCTCTGGGCGGCGTTGGCGAGATCGGCATGAATCTCGCTCTTTATGGCTA
CGGCCCGCCCGAGCATCGCCAATGGATCATGGTCGATTGCGGCGTCACCTTTCCCGGCCCCGACCTGCCGGGCGTCGACC
TCGTGCTGCCCGATATCCGCTTCCTCGCCAGTGAGCGCAAGAACCTCAAGGCGATCATCATCACCCATGCGCATGAAGAC
CATTATGGCGCGCTCGCCGATCTCTGGCCGGGCCTGAATGTGCCGGTCTATGCCTCGGGCTTTACCGCTGGTCTGCTCGA
AGCCAAGCGCAATTTCGAAAAGGCCAGGATCGGCGAAGTGCCGGTGACGCCGTTCAAGGCAGGCGACACGATCAATATCG
GCCCCTTCAGCATCGAAGGCGTGGCCGTCAACCATTCGATCCCCGAGCCGATGTCGCTGATGATCCGCACGCCGGTCGGC
AACGTCATCCATACCGGCGACTGGAAGATCGACCACGAGCCCTCGCTCGGCCCGTTGACCGATGAGACGCGGTTCCGCCA
GCTCGGCGACGAGGGCGTTCTGGCGCTGATGTGCGATTCTACCAATGCGCTGCGTGACGGTGTTTCGCCCTCCGAAAAGG
ATGTCTCGGAAAGCCTGCGCAAGATCATCGAGGATGCCGAGGGCCGGGTTGCGATCACCACCTTCTCGTCGAATGTCGGA
CGCATCCGCACCGTTGCCGAAGCCGCCGAGGCGGCTGGCCGCGAAGTGCTGCTGCTCGGCAGCTCGCTGAAGCGGGTCGT
CGACGTCGCCCAGGATATCGGCCTGATGGAGGGCGTAAAACCCTTCATCTCCGAGGAGGAATACGGCTACATCCCGCGCG
ACAAGGTCGTCGTCATCCTGACCGGCAGCCAGGGCGAGGCGCGGGCAGCGCTTGCCAAGCTCTCCCGCGACGAGATGCGC
AATGTTGCCTTTGCGGCAGGCGATATCGTCGTCTTTTCCTCCCGCGCCATTCCCGGCAACGAGAAGGCGATCCAGGACAT
CAAGAACGGCCTCGTCGAGCAGGGCGTGCACATCATCACCGATACCGAGGCCCTGGTTCACGTTTCCGGCCATCCTCGCC
GCAACGAGCTGCAGCGGATGTACGAGTGGACGCGGCCGAAGATCGTCGTGCCGGTGCATGGTGAGGCGACCCATCTGACG
GCGCATAAGGAACTTGCCGAGCAATCCGGCATCGCCCTGGTGCCGCGCGTGCGCAACGGCGATATTCTGCGGCTGGCGCC
CGGTCCAGCCGAGGTGATCGGCCAGGCGCCGCATGGCCGCATCTACAAGGACGGCTCGTTGATCGGCGATTTTGACGAGA
TGGGGATCGGCGAGCGCAAGAAGCTCTCCTATGTCGGCCATGTCGCGGTCAGCGTCGTGCTCGACGCCCGCTATGACATC
GTCGGTGATCCCGATCTCGTTTCGATCGGCCTGCCTGTTTATGACGACGAGGGCGAAGAGATGGAAGATACGCTCTTCGA
TGCGGCGATCAGCGCCATCGAAAGCATTCCGCGCGCCCGTCGCAAGGATATCGACATGGTGCAGGAGGCCGTGCGCCGCG
CCATCCGCGCCGCGGCAAACCATGCCTGGGGCAAGAAGCCGGTTGTCACCGCCTTCGTCACCAAGGTCTGA

Upstream 100 bases:

>100_bases
TTGATGATAATGGCTTGTTGATGCTCGATACCGGCACTGGCAGGATAATGCCCATTGCTGCCGGTGATGTGTTTTTTGGA
TAGCGGAAAAAACGAAAATT

Downstream 100 bases:

>100_bases
TCATGCTTGGCCGGGTAAACCACATCGCCATCGCCGTTCCCGATCTGGCAGCGGCGACCGCCGCCTATCGCGACACGCTG
GGTGCTGCCGTATCGCAGCC

Product: beta-lactamase

Products: NA

Alternate protein names: RNase J [H]

Number of amino acids: Translated: 556; Mature: 555

Protein sequence:

>556_residues
MAKQDELVFLPLGGVGEIGMNLALYGYGPPEHRQWIMVDCGVTFPGPDLPGVDLVLPDIRFLASERKNLKAIIITHAHED
HYGALADLWPGLNVPVYASGFTAGLLEAKRNFEKARIGEVPVTPFKAGDTINIGPFSIEGVAVNHSIPEPMSLMIRTPVG
NVIHTGDWKIDHEPSLGPLTDETRFRQLGDEGVLALMCDSTNALRDGVSPSEKDVSESLRKIIEDAEGRVAITTFSSNVG
RIRTVAEAAEAAGREVLLLGSSLKRVVDVAQDIGLMEGVKPFISEEEYGYIPRDKVVVILTGSQGEARAALAKLSRDEMR
NVAFAAGDIVVFSSRAIPGNEKAIQDIKNGLVEQGVHIITDTEALVHVSGHPRRNELQRMYEWTRPKIVVPVHGEATHLT
AHKELAEQSGIALVPRVRNGDILRLAPGPAEVIGQAPHGRIYKDGSLIGDFDEMGIGERKKLSYVGHVAVSVVLDARYDI
VGDPDLVSIGLPVYDDEGEEMEDTLFDAAISAIESIPRARRKDIDMVQEAVRRAIRAAANHAWGKKPVVTAFVTKV

Sequences:

>Translated_556_residues
MAKQDELVFLPLGGVGEIGMNLALYGYGPPEHRQWIMVDCGVTFPGPDLPGVDLVLPDIRFLASERKNLKAIIITHAHED
HYGALADLWPGLNVPVYASGFTAGLLEAKRNFEKARIGEVPVTPFKAGDTINIGPFSIEGVAVNHSIPEPMSLMIRTPVG
NVIHTGDWKIDHEPSLGPLTDETRFRQLGDEGVLALMCDSTNALRDGVSPSEKDVSESLRKIIEDAEGRVAITTFSSNVG
RIRTVAEAAEAAGREVLLLGSSLKRVVDVAQDIGLMEGVKPFISEEEYGYIPRDKVVVILTGSQGEARAALAKLSRDEMR
NVAFAAGDIVVFSSRAIPGNEKAIQDIKNGLVEQGVHIITDTEALVHVSGHPRRNELQRMYEWTRPKIVVPVHGEATHLT
AHKELAEQSGIALVPRVRNGDILRLAPGPAEVIGQAPHGRIYKDGSLIGDFDEMGIGERKKLSYVGHVAVSVVLDARYDI
VGDPDLVSIGLPVYDDEGEEMEDTLFDAAISAIESIPRARRKDIDMVQEAVRRAIRAAANHAWGKKPVVTAFVTKV
>Mature_555_residues
AKQDELVFLPLGGVGEIGMNLALYGYGPPEHRQWIMVDCGVTFPGPDLPGVDLVLPDIRFLASERKNLKAIIITHAHEDH
YGALADLWPGLNVPVYASGFTAGLLEAKRNFEKARIGEVPVTPFKAGDTINIGPFSIEGVAVNHSIPEPMSLMIRTPVGN
VIHTGDWKIDHEPSLGPLTDETRFRQLGDEGVLALMCDSTNALRDGVSPSEKDVSESLRKIIEDAEGRVAITTFSSNVGR
IRTVAEAAEAAGREVLLLGSSLKRVVDVAQDIGLMEGVKPFISEEEYGYIPRDKVVVILTGSQGEARAALAKLSRDEMRN
VAFAAGDIVVFSSRAIPGNEKAIQDIKNGLVEQGVHIITDTEALVHVSGHPRRNELQRMYEWTRPKIVVPVHGEATHLTA
HKELAEQSGIALVPRVRNGDILRLAPGPAEVIGQAPHGRIYKDGSLIGDFDEMGIGERKKLSYVGHVAVSVVLDARYDIV
GDPDLVSIGLPVYDDEGEEMEDTLFDAAISAIESIPRARRKDIDMVQEAVRRAIRAAANHAWGKKPVVTAFVTKV

Specific function: Unknown

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108
- InterPro:   IPR001587 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 60359; Mature: 60228

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKQDELVFLPLGGVGEIGMNLALYGYGPPEHRQWIMVDCGVTFPGPDLPGVDLVLPDIR
CCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCEECCHHH
FLASERKNLKAIIITHAHEDHYGALADLWPGLNVPVYASGFTAGLLEAKRNFEKARIGEV
HHHHCCCCCEEEEEEECCCCCCCCHHHHCCCCCCCEEECCCHHHHHHHHHCCCHHHCCCC
PVTPFKAGDTINIGPFSIEGVAVNHSIPEPMSLMIRTPVGNVIHTGDWKIDHEPSLGPLT
CCCCCCCCCEEECCCEEEEEEEECCCCCCCCEEEEECCCCCEEECCCEEECCCCCCCCCC
DETRFRQLGDEGVLALMCDSTNALRDGVSPSEKDVSESLRKIIEDAEGRVAITTFSSNVG
CHHHHHHCCCCCEEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCC
RIRTVAEAAEAAGREVLLLGSSLKRVVDVAQDIGLMEGVKPFISEEEYGYIPRDKVVVIL
HHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCEEEEE
TGSQGEARAALAKLSRDEMRNVAFAAGDIVVFSSRAIPGNEKAIQDIKNGLVEQGVHIIT
ECCCCHHHHHHHHHHHHHHHHHEEEECCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEE
DTEALVHVSGHPRRNELQRMYEWTRPKIVVPVHGEATHLTAHKELAEQSGIALVPRVRNG
CCCEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCEEEHHHHHHHHHCCCEEEEEECCC
DILRLAPGPAEVIGQAPHGRIYKDGSLIGDFDEMGIGERKKLSYVGHVAVSVVLDARYDI
CEEEECCCHHHHCCCCCCCCEEECCCEECCHHHCCCCCCHHHHHHHHEEEEEEEECCCCC
VGDPDLVSIGLPVYDDEGEEMEDTLFDAAISAIESIPRARRKDIDMVQEAVRRAIRAAAN
CCCCCEEEECCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
HAWGKKPVVTAFVTKV
CCCCCCCEEEEEEECC
>Mature Secondary Structure 
AKQDELVFLPLGGVGEIGMNLALYGYGPPEHRQWIMVDCGVTFPGPDLPGVDLVLPDIR
CCCCCEEEEECCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCEECCHHH
FLASERKNLKAIIITHAHEDHYGALADLWPGLNVPVYASGFTAGLLEAKRNFEKARIGEV
HHHHCCCCCEEEEEEECCCCCCCCHHHHCCCCCCCEEECCCHHHHHHHHHCCCHHHCCCC
PVTPFKAGDTINIGPFSIEGVAVNHSIPEPMSLMIRTPVGNVIHTGDWKIDHEPSLGPLT
CCCCCCCCCEEECCCEEEEEEEECCCCCCCCEEEEECCCCCEEECCCEEECCCCCCCCCC
DETRFRQLGDEGVLALMCDSTNALRDGVSPSEKDVSESLRKIIEDAEGRVAITTFSSNVG
CHHHHHHCCCCCEEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCC
RIRTVAEAAEAAGREVLLLGSSLKRVVDVAQDIGLMEGVKPFISEEEYGYIPRDKVVVIL
HHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCEEEEE
TGSQGEARAALAKLSRDEMRNVAFAAGDIVVFSSRAIPGNEKAIQDIKNGLVEQGVHIIT
ECCCCHHHHHHHHHHHHHHHHHEEEECCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEE
DTEALVHVSGHPRRNELQRMYEWTRPKIVVPVHGEATHLTAHKELAEQSGIALVPRVRNG
CCCEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCEEEHHHHHHHHHCCCEEEEEECCC
DILRLAPGPAEVIGQAPHGRIYKDGSLIGDFDEMGIGERKKLSYVGHVAVSVVLDARYDI
CEEEECCCHHHHCCCCCCCCEEECCCEECCHHHCCCCCCHHHHHHHHEEEEEEEECCCCC
VGDPDLVSIGLPVYDDEGEEMEDTLFDAAISAIESIPRARRKDIDMVQEAVRRAIRAAAN
CCCCCEEEECCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
HAWGKKPVVTAFVTKV
CCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]