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The map label for this gene is nqo3 [H]

Identifier: 209548870

GI number: 209548870

Start: 1283330

End: 1285411

Strand: Direct

Name: nqo3 [H]

Synonym: Rleg2_1267

Alternate gene names: 209548870

Gene position: 1283330-1285411 (Clockwise)

Preceding gene: 209548869

Following gene: 209548871

Centisome position: 28.28

GC content: 63.93

Gene sequence:

>2082_bases
ATGGCAAAACTGAAGATTGACGGCAACGAGATCGAAGTTCCGGATCATTACACGCTGTTGCAGGCGTGCGAGGATGCCGG
TGCCGAGGTTCCGCGCTTCTGCTTCCATGAGCGCCTGTCGGTTGCCGGCAATTGCCGCATGTGCCTTGTCGAGGTGAAGG
GCGGCCCGCCGAAGCCGCAGGCTTCCTGCGCCATGAGCGTACGCGACATCCGCGGCGGCCCGAACGGCGAACTGCCCGAG
GTCTTCACCAACACGCCGATGGTCAAGAAGGCCCGCGAAGGCGTGATGGAATTCCTGCTGATCAACCATCCGCTCGATTG
CCCGATCTGCGACCAGGGCGGCGAATGCGACCTGCAGGACCAGGCGATGGCCTTCGGCATCGACACCTCGCGCTACCAGG
AAGACAAACGCGCCGTCGAAGACAAGTATATCGGCCCGCTCGTCAAGACGGTGATGAACCGCTGCATCCACTGCACGCGC
TGCGTCCGCTTCACCACCGAGGTCGCCGGCATTTCCGAGCTTGGCCTGATCGGCCGCGGCGAAGATGCCGAAATCACCAC
CTATCTCGAACAGGCGATGACCTCCGAGCTTCAGGGCAATGTCGTCGATCTCTGCCCGGTGGGTGCGCTGACTTCCAAGC
CCTTCGCCTTCACCGCCCGTCCCTGGGAATTGAACAAGACCGAATCGATCGACGTCATGGATGCCGTCGGTTCGGCGATC
CGCGTCGATACCCGCGGCCGCGAAGTCATGCGTGTGCTGCCGCGCGTCAACGAGGCGATCAACGAAGAGTGGATCTCCGA
CAAGAGCCGCTTCATCTGGGACGGCCTGAAGACCCAGCGCCTCGACCGGCCTTACGTCCGCCGCGACGGCCGCCTGCAGC
CCGCCACCTGGGCCGAAGCCTTCGGCGCCATCAAGGCCGCCGTCGGCGCCACGTCGGGCGACAAGATCGGCGCGATCGCA
GGCGACCTTGCCTCGGTCGAGGAAATGTATGCGCTTTCCGAACTGGTGAAATCGCTCGGATCCGCCAATCTCGACTGTCG
CCAGGATGGGGCGGCACTCGATCCGTCGCTCGGCCGTGCAAGCTACCTCTTCAACCCGACCATTTCCGGCATCGACCAGG
CCGACGCGCTGCTGATCATCGGCGCCAATCCGCGCTTCGAGGCAGCCATCCTCAACGCCCGCATCCGCAAGCGCTGGCGC
CGCGGCAAGTTCCCGATCGGCGTCATCGGCGAGCCAGGCGAACTGCGCTACAGCTATGACTATCTCGGCGGTGGTCCCGA
CACGCTGAAGGATCTGGTCGACGGCGGCCACGCCTTCGCCGAGGTTCTGAAGAACGCCGCCAAGCCGATGATCATCATCG
GCCAGGGCGCGCTGTCGCGCACCGACGGCGCCGGTGTTCTCGCCAGTGCCGCCAAGCTTGCCGGTTCGGTCGGCGCAGTC
GTCGAAGGCTGGAACGGCTTTGCCGTCCTCCACACCGCCGCATCGCGCGTCGGCGGCCTCGACCTCGGCTTCGTGCCGGG
TGCCAAGGGTGTCAACGCCGCCGAAATGCTGACGGCGATGGATGTGCTCTTCCTGCTCGGCGCCGACGAGCTCGATTTCA
CCGCCAAGAAGGCCAAGCTTACCGTCTATATCGGCTCGCATGGCGACAACGGCGCCCATCATGCCGACGTCATTCTGCCG
GCCGCAGCCTATACCGAAAAGTCCGGCACCTGGGTCAACACCGAAGGCCGTGTCCAGATGGGCAACCGCGCAGGCTTTGC
GCCGGGCGACGCCCGCGAGGACTGGGCGATCATCCGTGCCCTTTCCGACGTGCTCGGCAAGAAGCTTCCGTTCGATTCGC
TGAGCGAATTGCGCGTCCGGCTCTATGCCGCTTTCCCGCATTTCGCCGCCATCGACGAGATCGCCGAAAACGATAGCGCC
CAAATTGCCGCAGTTGCGAAAAAAGCCGGCAAGATGAACAAGTCAGGGTTTGCGTCGCCGGTGAAAGACTTCTATTTGAC
GAACCCGATAGCGCGTGCCTCGGCAGTGATGGCGGAGTGCTCGGCATTGGCCCGCAACAACTTCAAAGTCGCGGCAGAGT
AA

Upstream 100 bases:

>100_bases
AGATGTCGGCAGGACGAAAGATCCGGCTTGGCAATGAGACTGTTGCAAAAATAGGTTTGTTTGCCGTCATCAGGCAAACG
GGAAACAGGACTGAGCGACG

Downstream 100 bases:

>100_bases
GGGCAGGGGACTATGGATTCTTTCTTTTCGACCTATGTCTTGCCGGCGATCATCATGATCGGTCAGTCGCTGCTGCTTCT
GGTCTGCCTGCTTGTCTTCA

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I, chain 3; NDH-1, chain 3 [H]

Number of amino acids: Translated: 693; Mature: 692

Protein sequence:

>693_residues
MAKLKIDGNEIEVPDHYTLLQACEDAGAEVPRFCFHERLSVAGNCRMCLVEVKGGPPKPQASCAMSVRDIRGGPNGELPE
VFTNTPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQAMAFGIDTSRYQEDKRAVEDKYIGPLVKTVMNRCIHCTR
CVRFTTEVAGISELGLIGRGEDAEITTYLEQAMTSELQGNVVDLCPVGALTSKPFAFTARPWELNKTESIDVMDAVGSAI
RVDTRGREVMRVLPRVNEAINEEWISDKSRFIWDGLKTQRLDRPYVRRDGRLQPATWAEAFGAIKAAVGATSGDKIGAIA
GDLASVEEMYALSELVKSLGSANLDCRQDGAALDPSLGRASYLFNPTISGIDQADALLIIGANPRFEAAILNARIRKRWR
RGKFPIGVIGEPGELRYSYDYLGGGPDTLKDLVDGGHAFAEVLKNAAKPMIIIGQGALSRTDGAGVLASAAKLAGSVGAV
VEGWNGFAVLHTAASRVGGLDLGFVPGAKGVNAAEMLTAMDVLFLLGADELDFTAKKAKLTVYIGSHGDNGAHHADVILP
AAAYTEKSGTWVNTEGRVQMGNRAGFAPGDAREDWAIIRALSDVLGKKLPFDSLSELRVRLYAAFPHFAAIDEIAENDSA
QIAAVAKKAGKMNKSGFASPVKDFYLTNPIARASAVMAECSALARNNFKVAAE

Sequences:

>Translated_693_residues
MAKLKIDGNEIEVPDHYTLLQACEDAGAEVPRFCFHERLSVAGNCRMCLVEVKGGPPKPQASCAMSVRDIRGGPNGELPE
VFTNTPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQAMAFGIDTSRYQEDKRAVEDKYIGPLVKTVMNRCIHCTR
CVRFTTEVAGISELGLIGRGEDAEITTYLEQAMTSELQGNVVDLCPVGALTSKPFAFTARPWELNKTESIDVMDAVGSAI
RVDTRGREVMRVLPRVNEAINEEWISDKSRFIWDGLKTQRLDRPYVRRDGRLQPATWAEAFGAIKAAVGATSGDKIGAIA
GDLASVEEMYALSELVKSLGSANLDCRQDGAALDPSLGRASYLFNPTISGIDQADALLIIGANPRFEAAILNARIRKRWR
RGKFPIGVIGEPGELRYSYDYLGGGPDTLKDLVDGGHAFAEVLKNAAKPMIIIGQGALSRTDGAGVLASAAKLAGSVGAV
VEGWNGFAVLHTAASRVGGLDLGFVPGAKGVNAAEMLTAMDVLFLLGADELDFTAKKAKLTVYIGSHGDNGAHHADVILP
AAAYTEKSGTWVNTEGRVQMGNRAGFAPGDAREDWAIIRALSDVLGKKLPFDSLSELRVRLYAAFPHFAAIDEIAENDSA
QIAAVAKKAGKMNKSGFASPVKDFYLTNPIARASAVMAECSALARNNFKVAAE
>Mature_692_residues
AKLKIDGNEIEVPDHYTLLQACEDAGAEVPRFCFHERLSVAGNCRMCLVEVKGGPPKPQASCAMSVRDIRGGPNGELPEV
FTNTPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQAMAFGIDTSRYQEDKRAVEDKYIGPLVKTVMNRCIHCTRC
VRFTTEVAGISELGLIGRGEDAEITTYLEQAMTSELQGNVVDLCPVGALTSKPFAFTARPWELNKTESIDVMDAVGSAIR
VDTRGREVMRVLPRVNEAINEEWISDKSRFIWDGLKTQRLDRPYVRRDGRLQPATWAEAFGAIKAAVGATSGDKIGAIAG
DLASVEEMYALSELVKSLGSANLDCRQDGAALDPSLGRASYLFNPTISGIDQADALLIIGANPRFEAAILNARIRKRWRR
GKFPIGVIGEPGELRYSYDYLGGGPDTLKDLVDGGHAFAEVLKNAAKPMIIIGQGALSRTDGAGVLASAAKLAGSVGAVV
EGWNGFAVLHTAASRVGGLDLGFVPGAKGVNAAEMLTAMDVLFLLGADELDFTAKKAKLTVYIGSHGDNGAHHADVILPA
AAYTEKSGTWVNTEGRVQMGNRAGFAPGDAREDWAIIRALSDVLGKKLPFDSLSELRVRLYAAFPHFAAIDEIAENDSAQ
IAAVAKKAGKMNKSGFASPVKDFYLTNPIARASAVMAECSALARNNFKVAAE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=694, Percent_Identity=51.1527377521614, Blast_Score=690, Evalue=0.0,
Organism=Escherichia coli, GI145693161, Length=709, Percent_Identity=26.657263751763, Blast_Score=196, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17565758, Length=700, Percent_Identity=49, Blast_Score=623, Evalue=1e-179,
Organism=Caenorhabditis elegans, GI32566231, Length=587, Percent_Identity=51.1073253833049, Blast_Score=565, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI193209088, Length=258, Percent_Identity=61.2403100775194, Blast_Score=323, Evalue=3e-88,
Organism=Drosophila melanogaster, GI24640559, Length=684, Percent_Identity=50.4385964912281, Blast_Score=642, Evalue=0.0,
Organism=Drosophila melanogaster, GI24640557, Length=684, Percent_Identity=50.4385964912281, Blast_Score=642, Evalue=0.0,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 74383; Mature: 74251

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLKIDGNEIEVPDHYTLLQACEDAGAEVPRFCFHERLSVAGNCRMCLVEVKGGPPKPQ
CCEEEECCCEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCC
ASCAMSVRDIRGGPNGELPEVFTNTPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQD
HHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
QAMAFGIDTSRYQEDKRAVEDKYIGPLVKTVMNRCIHCTRCVRFTTEVAGISELGLIGRG
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCC
EDAEITTYLEQAMTSELQGNVVDLCPVGALTSKPFAFTARPWELNKTESIDVMDAVGSAI
CCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEECCCCCCCCCCCCHHHHHCCCEE
RVDTRGREVMRVLPRVNEAINEEWISDKSRFIWDGLKTQRLDRPYVRRDGRLQPATWAEA
EECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHCCCCHHHCCCCCCCHHHHHH
FGAIKAAVGATSGDKIGAIAGDLASVEEMYALSELVKSLGSANLDCRQDGAALDPSLGRA
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
SYLFNPTISGIDQADALLIIGANPRFEAAILNARIRKRWRRGKFPIGVIGEPGELRYSYD
EEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEC
YLGGGPDTLKDLVDGGHAFAEVLKNAAKPMIIIGQGALSRTDGAGVLASAAKLAGSVGAV
CCCCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCHHHH
VEGWNGFAVLHTAASRVGGLDLGFVPGAKGVNAAEMLTAMDVLFLLGADELDFTAKKAKL
EECCCCEEHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEE
TVYIGSHGDNGAHHADVILPAAAYTEKSGTWVNTEGRVQMGNRAGFAPGDAREDWAIIRA
EEEEECCCCCCCCCCCEEEEHHHHCCCCCCEECCCCCEEECCCCCCCCCCCCHHHHHHHH
LSDVLGKKLPFDSLSELRVRLYAAFPHFAAIDEIAENDSAQIAAVAKKAGKMNKSGFASP
HHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCH
VKDFYLTNPIARASAVMAECSALARNNFKVAAE
HHHHHHCCHHHHHHHHHHHHHHHHCCCEEEECC
>Mature Secondary Structure 
AKLKIDGNEIEVPDHYTLLQACEDAGAEVPRFCFHERLSVAGNCRMCLVEVKGGPPKPQ
CEEEECCCEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCC
ASCAMSVRDIRGGPNGELPEVFTNTPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQD
HHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
QAMAFGIDTSRYQEDKRAVEDKYIGPLVKTVMNRCIHCTRCVRFTTEVAGISELGLIGRG
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCC
EDAEITTYLEQAMTSELQGNVVDLCPVGALTSKPFAFTARPWELNKTESIDVMDAVGSAI
CCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEECCCCCCCCCCCCHHHHHCCCEE
RVDTRGREVMRVLPRVNEAINEEWISDKSRFIWDGLKTQRLDRPYVRRDGRLQPATWAEA
EECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHCCCCHHHCCCCCCCHHHHHH
FGAIKAAVGATSGDKIGAIAGDLASVEEMYALSELVKSLGSANLDCRQDGAALDPSLGRA
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
SYLFNPTISGIDQADALLIIGANPRFEAAILNARIRKRWRRGKFPIGVIGEPGELRYSYD
EEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEC
YLGGGPDTLKDLVDGGHAFAEVLKNAAKPMIIIGQGALSRTDGAGVLASAAKLAGSVGAV
CCCCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCHHHH
VEGWNGFAVLHTAASRVGGLDLGFVPGAKGVNAAEMLTAMDVLFLLGADELDFTAKKAKL
EECCCCEEHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEE
TVYIGSHGDNGAHHADVILPAAAYTEKSGTWVNTEGRVQMGNRAGFAPGDAREDWAIIRA
EEEEECCCCCCCCCCCEEEEHHHHCCCCCCEECCCCCEEECCCCCCCCCCCCHHHHHHHH
LSDVLGKKLPFDSLSELRVRLYAAFPHFAAIDEIAENDSAQIAAVAKKAGKMNKSGFASP
HHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCH
VKDFYLTNPIARASAVMAECSALARNNFKVAAE
HHHHHHCCHHHHHHHHHHHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1605643; 8422400 [H]