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The map label for this gene is hupA [C]

Identifier: 209548853

GI number: 209548853

Start: 1267307

End: 1267582

Strand: Direct

Name: hupA [C]

Synonym: Rleg2_1250

Alternate gene names: 209548853

Gene position: 1267307-1267582 (Clockwise)

Preceding gene: 209548852

Following gene: 209548854

Centisome position: 27.93

GC content: 60.14

Gene sequence:

>276_bases
ATGAACAAGAATGAACTCGTGTCCGCAGTCGCCGAAAAGGCAGGACTGACGAAGTCTGACGCGGCTTCCGCTGTTGACGC
GGTTTTTGACGTTGTCCAGGGTGAACTCAAGAACAAGGGCGACATCCGTCTCGCAGGGTTCGGCAGCTTCACCGTTTCTC
ATCGTGCCGCATCGAAGGGCCGCAACCCGTCGACGGGCGCTGAAGTCGACATTCCGGCTCGCAACGTGCCGAAGTTCACG
CCCGGCAAGGGCCTGAAGGACGCCGTCAACGGCTGA

Upstream 100 bases:

>100_bases
GATTTGCAGGGCTTTTGGGTTCCCGGCGGGCCTGATGAAACCTATTCTGCGCCTAGCTTACTTTTGAGTCGTTTCGTACC
ATTTAGAAAGGGGTGGAAAC

Downstream 100 bases:

>100_bases
TCTGAGATTATCCGCCAGCCGTAAACGAGACCGGCTGCGCAGGATTTGGGAGGGGTTCGGCTTTGCCGGACCCCTTTGCT
TTGTGCGCCCTTTTGCTCTT

Product: histone family protein DNA-binding protein

Products: NA

Alternate protein names: HU-like protein; Px [H]

Number of amino acids: Translated: 91; Mature: 91

Protein sequence:

>91_residues
MNKNELVSAVAEKAGLTKSDAASAVDAVFDVVQGELKNKGDIRLAGFGSFTVSHRAASKGRNPSTGAEVDIPARNVPKFT
PGKGLKDAVNG

Sequences:

>Translated_91_residues
MNKNELVSAVAEKAGLTKSDAASAVDAVFDVVQGELKNKGDIRLAGFGSFTVSHRAASKGRNPSTGAEVDIPARNVPKFT
PGKGLKDAVNG
>Mature_91_residues
MNKNELVSAVAEKAGLTKSDAASAVDAVFDVVQGELKNKGDIRLAGFGSFTVSHRAASKGRNPSTGAEVDIPARNVPKFT
PGKGLKDAVNG

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Binds to nod promoters and induces DNA binding [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=48.314606741573, Blast_Score=92, Evalue=9e-21,
Organism=Escherichia coli, GI1786644, Length=90, Percent_Identity=48.8888888888889, Blast_Score=86, Evalue=4e-19,
Organism=Escherichia coli, GI1788005, Length=89, Percent_Identity=37.0786516853933, Blast_Score=69, Evalue=7e-14,
Organism=Escherichia coli, GI1787141, Length=91, Percent_Identity=35.1648351648352, Blast_Score=65, Evalue=1e-12,

Paralogues:

None

Copy number: 1380 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9354; Mature: 9354

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKNELVSAVAEKAGLTKSDAASAVDAVFDVVQGELKNKGDIRLAGFGSFTVSHRAASKG
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHCC
RNPSTGAEVDIPARNVPKFTPGKGLKDAVNG
CCCCCCCEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNKNELVSAVAEKAGLTKSDAASAVDAVFDVVQGELKNKGDIRLAGFGSFTVSHRAASKG
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHCC
RNPSTGAEVDIPARNVPKFTPGKGLKDAVNG
CCCCCCCEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 4038648; 9685414 [H]