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The map label for this gene is clpX [H]

Identifier: 209548851

GI number: 209548851

Start: 1262984

End: 1264261

Strand: Direct

Name: clpX [H]

Synonym: Rleg2_1248

Alternate gene names: 209548851

Gene position: 1262984-1264261 (Clockwise)

Preceding gene: 209548850

Following gene: 209548852

Centisome position: 27.83

GC content: 61.35

Gene sequence:

>1278_bases
ATGAGCAAGGTCAGCGGCAGCAACGGCGGCGACTCCAAGAACACACTCTATTGTTCGTTCTGCGGAAAGAGCCAGCACGA
AGTCCGGAAACTGATTGCCGGGCCGACCGTCTTCATCTGCGATGAATGCGTCGAATTGTGCATGGACATCATCCGCGAGG
AGAACAAGTCCTCGATGGTCAAGTCCCGCGATGGCGTTCCGACGCCCCAGGACATCATCAAGGTCCTCGACGAATACGTC
ATTGGCCAGCGGCAGGCGAAGAAGATCCTGTCGGTCGCCGTTCACAACCATTACAAGCGCCTGGCGCACGCCTCCAAGAA
CGGCGAAGTCGAGCTGGCGAAGTCGAACATCATGCTGGTTGGCCCGACCGGCTGCGGCAAGACCTATCTCGCCCAGACGC
TCGCCCGCATCATCGACGTTCCCTTCACCATGGCCGATGCGACGACGCTGACCGAAGCCGGTTACGTCGGCGAAGACGTC
GAAAACATCATCCTCAAGCTTCTGCAGTCGGCCGACTACAATGTCGAGCGCGCCCAGCGCGGCATCGTCTACATCGACGA
AGTCGACAAGATTTCGCGCAAGTCCGACAATCCGTCGATCACCCGCGACGTGTCGGGCGAGGGCGTGCAGCAGGCGCTGT
TGAAGATCATGGAAGGCACGGTGGCTTCCGTTCCGCCGCAGGGCGGCCGCAAGCACCCGCAGCAGGAATTCCTGCAGGTC
GACACGACCAACATCCTGTTCATCTGCGGCGGCGCCTTTGCCGGCCTCGACAAGATCATCTCCGCCCGCGGCGAGAAGAC
CTCGATCGGCTTCGGCGCGACCGTCAAGGCGCAGGACGACCGCCGCGTCGGCGAAGTCCTGCGCGAACTGGAGCCGGAAG
ACCTGGTCAAGTTCGGCCTTATTCCCGAGTTCATCGGCCGTCTGCCGGTTCTGGCGACGCTCGAGGACCTCGACGAAGAT
GCGCTGATCCAGATCCTGTCCGAGCCGAAGAATGCGTTGATCAAGCAGTACCAGCGCCTGTTCGAGATGGAAGACGTGGA
GCTGACCTTCCATGAGGATGCCCTGCGCGAAATCGCCCGCAAGGCGATCGTCCGCAAGACCGGCGCCCGCGGCCTTCGCT
CGATCATGGAGAAGATCCTGCTCGACACGATGTTCGAATTGCCGACGCTGGAAGGCGTGCGCGAAGTCGTCATCTCCGAG
GAAGTGGTGCGCGGTTCGGCCCGCCCGCTTTACATCTATGCCGATCGTCAGGAAGAAAAGGCCAACGCTTCGGCGTAA

Upstream 100 bases:

>100_bases
GCCCTTCTCGGCAAAGGCTCCGGTGACGGAGTGCCGCCAGGAGCTGATTGAGTGGACCGCGATTTCGCCTTGAAATGCGG
CGTGCTGGAAGGAAAGTGAT

Downstream 100 bases:

>100_bases
CCTTTGCGCTTTCGCACGATTATTTTGGGGGCTTGCCATCGGCAGGCCCCTTTCTATTTGAAAAACCATCCGAGGCACTG
TTAGTATTTTGCCGGTGGGA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MSKVSGSNGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSMVKSRDGVPTPQDIIKVLDEYV
IGQRQAKKILSVAVHNHYKRLAHASKNGEVELAKSNIMLVGPTGCGKTYLAQTLARIIDVPFTMADATTLTEAGYVGEDV
ENIILKLLQSADYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQV
DTTNILFICGGAFAGLDKIISARGEKTSIGFGATVKAQDDRRVGEVLRELEPEDLVKFGLIPEFIGRLPVLATLEDLDED
ALIQILSEPKNALIKQYQRLFEMEDVELTFHEDALREIARKAIVRKTGARGLRSIMEKILLDTMFELPTLEGVREVVISE
EVVRGSARPLYIYADRQEEKANASA

Sequences:

>Translated_425_residues
MSKVSGSNGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSMVKSRDGVPTPQDIIKVLDEYV
IGQRQAKKILSVAVHNHYKRLAHASKNGEVELAKSNIMLVGPTGCGKTYLAQTLARIIDVPFTMADATTLTEAGYVGEDV
ENIILKLLQSADYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQV
DTTNILFICGGAFAGLDKIISARGEKTSIGFGATVKAQDDRRVGEVLRELEPEDLVKFGLIPEFIGRLPVLATLEDLDED
ALIQILSEPKNALIKQYQRLFEMEDVELTFHEDALREIARKAIVRKTGARGLRSIMEKILLDTMFELPTLEGVREVVISE
EVVRGSARPLYIYADRQEEKANASA
>Mature_424_residues
SKVSGSNGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSMVKSRDGVPTPQDIIKVLDEYVI
GQRQAKKILSVAVHNHYKRLAHASKNGEVELAKSNIMLVGPTGCGKTYLAQTLARIIDVPFTMADATTLTEAGYVGEDVE
NIILKLLQSADYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVD
TTNILFICGGAFAGLDKIISARGEKTSIGFGATVKAQDDRRVGEVLRELEPEDLVKFGLIPEFIGRLPVLATLEDLDEDA
LIQILSEPKNALIKQYQRLFEMEDVELTFHEDALREIARKAIVRKTGARGLRSIMEKILLDTMFELPTLEGVREVVISEE
VVRGSARPLYIYADRQEEKANASA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=338, Percent_Identity=53.2544378698225, Blast_Score=333, Evalue=2e-91,
Organism=Escherichia coli, GI1786642, Length=415, Percent_Identity=70.8433734939759, Blast_Score=598, Evalue=1e-172,
Organism=Escherichia coli, GI1790366, Length=104, Percent_Identity=39.4230769230769, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71982908, Length=321, Percent_Identity=47.0404984423676, Blast_Score=283, Evalue=9e-77,
Organism=Caenorhabditis elegans, GI71982905, Length=321, Percent_Identity=47.0404984423676, Blast_Score=283, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI71988663, Length=390, Percent_Identity=38.2051282051282, Blast_Score=250, Evalue=9e-67,
Organism=Caenorhabditis elegans, GI71988660, Length=258, Percent_Identity=38.7596899224806, Blast_Score=166, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6319704, Length=432, Percent_Identity=38.1944444444444, Blast_Score=268, Evalue=2e-72,
Organism=Drosophila melanogaster, GI24648291, Length=320, Percent_Identity=50, Blast_Score=312, Evalue=2e-85,
Organism=Drosophila melanogaster, GI24648289, Length=320, Percent_Identity=50, Blast_Score=312, Evalue=3e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46953; Mature: 46822

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVSGSNGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSMV
CCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHH
KSRDGVPTPQDIIKVLDEYVIGQRQAKKILSVAVHNHYKRLAHASKNGEVELAKSNIMLV
HCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEE
GPTGCGKTYLAQTLARIIDVPFTMADATTLTEAGYVGEDVENIILKLLQSADYNVERAQR
CCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHC
GIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQV
CCEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHH
DTTNILFICGGAFAGLDKIISARGEKTSIGFGATVKAQDDRRVGEVLRELEPEDLVKFGL
CCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHCCHHHHHHHCC
IPEFIGRLPVLATLEDLDEDALIQILSEPKNALIKQYQRLFEMEDVELTFHEDALREIAR
HHHHHCCCCHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHH
KAIVRKTGARGLRSIMEKILLDTMFELPTLEGVREVVISEEVVRGSARPLYIYADRQEEK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
ANASA
CCCCC
>Mature Secondary Structure 
SKVSGSNGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSMV
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHH
KSRDGVPTPQDIIKVLDEYVIGQRQAKKILSVAVHNHYKRLAHASKNGEVELAKSNIMLV
HCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEE
GPTGCGKTYLAQTLARIIDVPFTMADATTLTEAGYVGEDVENIILKLLQSADYNVERAQR
CCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHC
GIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQV
CCEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHH
DTTNILFICGGAFAGLDKIISARGEKTSIGFGATVKAQDDRRVGEVLRELEPEDLVKFGL
CCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHCCHHHHHHHCC
IPEFIGRLPVLATLEDLDEDALIQILSEPKNALIKQYQRLFEMEDVELTFHEDALREIAR
HHHHHCCCCHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHH
KAIVRKTGARGLRSIMEKILLDTMFELPTLEGVREVVISEEVVRGSARPLYIYADRQEEK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
ANASA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]