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The map label for this gene is ctaA [H]

Identifier: 209548831

GI number: 209548831

Start: 1241262

End: 1242365

Strand: Direct

Name: ctaA [H]

Synonym: Rleg2_1228

Alternate gene names: 209548831

Gene position: 1241262-1242365 (Clockwise)

Preceding gene: 209548828

Following gene: 209548836

Centisome position: 27.35

GC content: 63.59

Gene sequence:

>1104_bases
ATGGCCGTCGCAAACCCGACCACGGAACAGGCGATCCTCAGCGAAGTGCGCAAGCAGAACCGCGACCGCCGCGCCTTGCG
CTTCTGGCTTGGTTTCGTGCTTTTGGCGCTCTTCTGTCTCGTGCTCGTCGGCGGCGCCACGCGGCTGACCAATTCCGGCC
TGTCGATCACCGAGTGGAGGCCGATTCACGGCGTCATCCCGCCGCTGTCGGCTGCCGAATGGGAGGAAGAATTCCGCCTC
TACCAGCGCATTCCGGAATTTCAGCAATTGAACAATTCCATGACCGTCGACGAGTTCAAGGGCATCTTCTGGTGGGAATG
GGCCCACCGGCTGATCGCCCGCGGCATCGGCGTGATCTTCGCGTTGCCGCTCCTCTATTTCTGGCTGACGGGGCGAATCG
AAAAGCGCCTGCGCTGGCCACTCGTCGGCATCCTGGCGCTCGGCGGCCTGCAGGGTTTTATCGGCTGGTGGATGGTGTCC
TCGGGCCTGTCCGTCCGCACCGACGTCAGCCAGTACAGGCTGGCGACGCATTTGGTCATGGCCTGCCTGATCTTTGCCGG
CTGCATGTGGATCATGCGCGGGCTCTCCCCGCATTCCAACGATCCGGCGCCGGCCCGCAGCTCGCGCGGTTTTGCCGCCA
CGATCGCCATCTTCGCGCTGTTCCAGATCTATCTCGGCGCGCTGGTGGCGGGACTCGACGCCGGTTTTTCCTACAATACC
TGGCCGCTGATGGATGGCGCGCTCATTCCGTCTGATCTCTTGATCCAGCAGCCCTTCTGGATCAATGCCTTCGAGAACCC
GAAGACGGTGCAGTTCATCCACCGCATCGGCGCCTATACGCTCTTCGCATTGACCTTGATCAACATGGTGATCGCGCTTC
GCGCTGCCCCCTGGACCACCCATGCCCGCCGCGCCGTCGTGCTTTTCTCCCTGGTGACGCTGCAGGCGGCCATCGGCATC
GCCACGCTGCTGATGCAGGTGCCGCTTCACTGGGGCTTGCTGCATCAGGCCGGCGCCCTGGTGGTTTTCGGTTTCGCCAT
CGCCAACTGGCGCGGCTTTTACGGCGAATACCCGCACGCCACCGCAATCGCGGAGCGCGGCTGA

Upstream 100 bases:

>100_bases
AGGGACGGGGCGGACCGGCGCGACGGCATGCCGCAAAGGTACGGGGCTTGTTTTGCATGAGCCGGTGGGGCAAATCAACT
GCCGGATAGAAGGAGACATC

Downstream 100 bases:

>100_bases
AGCGGTGTCGTAAGGCACTCTAACGCAGCACCCCATCGAGCAGCGGCATGCCGATGATCGCCGCGGCAGCGATCAGGATG
TAGCAGGCGATGCGGAAGGT

Product: cytochrome oxidase assembly

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MAVANPTTEQAILSEVRKQNRDRRALRFWLGFVLLALFCLVLVGGATRLTNSGLSITEWRPIHGVIPPLSAAEWEEEFRL
YQRIPEFQQLNNSMTVDEFKGIFWWEWAHRLIARGIGVIFALPLLYFWLTGRIEKRLRWPLVGILALGGLQGFIGWWMVS
SGLSVRTDVSQYRLATHLVMACLIFAGCMWIMRGLSPHSNDPAPARSSRGFAATIAIFALFQIYLGALVAGLDAGFSYNT
WPLMDGALIPSDLLIQQPFWINAFENPKTVQFIHRIGAYTLFALTLINMVIALRAAPWTTHARRAVVLFSLVTLQAAIGI
ATLLMQVPLHWGLLHQAGALVVFGFAIANWRGFYGEYPHATAIAERG

Sequences:

>Translated_367_residues
MAVANPTTEQAILSEVRKQNRDRRALRFWLGFVLLALFCLVLVGGATRLTNSGLSITEWRPIHGVIPPLSAAEWEEEFRL
YQRIPEFQQLNNSMTVDEFKGIFWWEWAHRLIARGIGVIFALPLLYFWLTGRIEKRLRWPLVGILALGGLQGFIGWWMVS
SGLSVRTDVSQYRLATHLVMACLIFAGCMWIMRGLSPHSNDPAPARSSRGFAATIAIFALFQIYLGALVAGLDAGFSYNT
WPLMDGALIPSDLLIQQPFWINAFENPKTVQFIHRIGAYTLFALTLINMVIALRAAPWTTHARRAVVLFSLVTLQAAIGI
ATLLMQVPLHWGLLHQAGALVVFGFAIANWRGFYGEYPHATAIAERG
>Mature_366_residues
AVANPTTEQAILSEVRKQNRDRRALRFWLGFVLLALFCLVLVGGATRLTNSGLSITEWRPIHGVIPPLSAAEWEEEFRLY
QRIPEFQQLNNSMTVDEFKGIFWWEWAHRLIARGIGVIFALPLLYFWLTGRIEKRLRWPLVGILALGGLQGFIGWWMVSS
GLSVRTDVSQYRLATHLVMACLIFAGCMWIMRGLSPHSNDPAPARSSRGFAATIAIFALFQIYLGALVAGLDAGFSYNTW
PLMDGALIPSDLLIQQPFWINAFENPKTVQFIHRIGAYTLFALTLINMVIALRAAPWTTHARRAVVLFSLVTLQAAIGIA
TLLMQVPLHWGLLHQAGALVVFGFAIANWRGFYGEYPHATAIAERG

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group [H]

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI17921985, Length=317, Percent_Identity=39.7476340694006, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI17921987, Length=288, Percent_Identity=39.2361111111111, Blast_Score=185, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI17536069, Length=342, Percent_Identity=37.719298245614, Blast_Score=205, Evalue=4e-53,
Organism=Saccharomyces cerevisiae, GI6320989, Length=384, Percent_Identity=37.5, Blast_Score=211, Evalue=2e-55,
Organism=Drosophila melanogaster, GI19922860, Length=355, Percent_Identity=36.6197183098592, Blast_Score=193, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003780 [H]

Pfam domain/function: PF02628 COX15-CtaA [H]

EC number: NA

Molecular weight: Translated: 41120; Mature: 40989

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVANPTTEQAILSEVRKQNRDRRALRFWLGFVLLALFCLVLVGGATRLTNSGLSITEWR
CCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCC
PIHGVIPPLSAAEWEEEFRLYQRIPEFQQLNNSMTVDEFKGIFWWEWAHRLIARGIGVIF
CCCCCCCCCCHHHHHHHHHHHHHCCHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHH
ALPLLYFWLTGRIEKRLRWPLVGILALGGLQGFIGWWMVSSGLSVRTDVSQYRLATHLVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ACLIFAGCMWIMRGLSPHSNDPAPARSSRGFAATIAIFALFQIYLGALVAGLDAGFSYNT
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
WPLMDGALIPSDLLIQQPFWINAFENPKTVQFIHRIGAYTLFALTLINMVIALRAAPWTT
CCCCCCCCCCHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
HARRAVVLFSLVTLQAAIGIATLLMQVPLHWGLLHQAGALVVFGFAIANWRGFYGEYPHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCH
TAIAERG
HHHCCCC
>Mature Secondary Structure 
AVANPTTEQAILSEVRKQNRDRRALRFWLGFVLLALFCLVLVGGATRLTNSGLSITEWR
CCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCC
PIHGVIPPLSAAEWEEEFRLYQRIPEFQQLNNSMTVDEFKGIFWWEWAHRLIARGIGVIF
CCCCCCCCCCHHHHHHHHHHHHHCCHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHH
ALPLLYFWLTGRIEKRLRWPLVGILALGGLQGFIGWWMVSSGLSVRTDVSQYRLATHLVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ACLIFAGCMWIMRGLSPHSNDPAPARSSRGFAATIAIFALFQIYLGALVAGLDAGFSYNT
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
WPLMDGALIPSDLLIQQPFWINAFENPKTVQFIHRIGAYTLFALTLINMVIALRAAPWTT
CCCCCCCCCCHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
HARRAVVLFSLVTLQAAIGIATLLMQVPLHWGLLHQAGALVVFGFAIANWRGFYGEYPHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCH
TAIAERG
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA