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The map label for this gene is ribE [H]

Identifier: 209548783

GI number: 209548783

Start: 1191559

End: 1192170

Strand: Direct

Name: ribE [H]

Synonym: Rleg2_1180

Alternate gene names: 209548783

Gene position: 1191559-1192170 (Clockwise)

Preceding gene: 209548782

Following gene: 209548793

Centisome position: 26.26

GC content: 64.22

Gene sequence:

>612_bases
ATGTTTACCGGAATAGTCACCGATGTCGGCACGGTCGAATCCGTTTCCCCGCTGAAGGAAGGCATCCGGCTGCGGGTCGC
CACCGCCTACGATCCCGCAACGATCGACATGGGCGCCTCGATCTCGCATTCCGGCATCTGCCTGACCGTGACGGGTCTGC
CTGATGAAGGCAGCAACGGCCGCTGGTTCGAGGTCGAGGCCTGGGAAGAGGCGCTGCGGCTGACGACGATCGGCACCTGG
CGGGAAGGCAGCCGCATCAATCTCGAACGGTCACTGAAAATAGGCGATGAACTCGGCGGTCACATCGTTTCCGGCCATGT
CGACGGCAAGGCGGAAATCCTCTCGGTGACATCGGAGGGCGACGCCACCCGTTACCGGCTGCGCGCGCCCGAGCATCTGG
CGAAATTCGTCGCCCCCAAGGGCTCGATCGCCCTCGACGGCACCTCGCTGACCGTCAATGCGGTCGACGGCACCGATTTC
GACGTCCTGCTCATCCGCCACACGCTCGAGGTCACCACCTGGGGCGAACGCAAGGCCGGCGATTTCGTCAATTTCGAAGT
CGACACCATGGCGCGTTACGCCGCCCGGCTGGCGGAATTCCCGAGCGCCTGA

Upstream 100 bases:

>100_bases
AATCGCCGCTTGATGCAACCGACATACCACCGGGTTTTGCCCAGACGGGCACGCAGATGTTCGGCGAAGATCGCCTGGAC
GAATACGAAAGAGGGCTTTG

Downstream 100 bases:

>100_bases
ATCGAAAACCTGTAGCGGTTTCCAAGGTCACAAGTCGCTCACCAATCCGGGGAGAGCTTCGTCAGGTACTGGCCATAGGC
GCTCTTGCCGAGCTTCTCCG

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MFTGIVTDVGTVESVSPLKEGIRLRVATAYDPATIDMGASISHSGICLTVTGLPDEGSNGRWFEVEAWEEALRLTTIGTW
REGSRINLERSLKIGDELGGHIVSGHVDGKAEILSVTSEGDATRYRLRAPEHLAKFVAPKGSIALDGTSLTVNAVDGTDF
DVLLIRHTLEVTTWGERKAGDFVNFEVDTMARYAARLAEFPSA

Sequences:

>Translated_203_residues
MFTGIVTDVGTVESVSPLKEGIRLRVATAYDPATIDMGASISHSGICLTVTGLPDEGSNGRWFEVEAWEEALRLTTIGTW
REGSRINLERSLKIGDELGGHIVSGHVDGKAEILSVTSEGDATRYRLRAPEHLAKFVAPKGSIALDGTSLTVNAVDGTDF
DVLLIRHTLEVTTWGERKAGDFVNFEVDTMARYAARLAEFPSA
>Mature_203_residues
MFTGIVTDVGTVESVSPLKEGIRLRVATAYDPATIDMGASISHSGICLTVTGLPDEGSNGRWFEVEAWEEALRLTTIGTW
REGSRINLERSLKIGDELGGHIVSGHVDGKAEILSVTSEGDATRYRLRAPEHLAKFVAPKGSIALDGTSLTVNAVDGTDF
DVLLIRHTLEVTTWGERKAGDFVNFEVDTMARYAARLAEFPSA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=191, Percent_Identity=39.2670157068063, Blast_Score=117, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6319733, Length=209, Percent_Identity=34.9282296650718, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 21920; Mature: 21920

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVTDVGTVESVSPLKEGIRLRVATAYDPATIDMGASISHSGICLTVTGLPDEGSNG
CCCEEECCCCCCCCHHHHHCCEEEEEEECCCCEEEECCCCCCCCCEEEEEEECCCCCCCC
RWFEVEAWEEALRLTTIGTWREGSRINLERSLKIGDELGGHIVSGHVDGKAEILSVTSEG
CEEEEHHHHHHEEEEEEECCCCCCEEEEEEEEECCCCCCCEEEEEECCCCEEEEEEECCC
DATRYRLRAPEHLAKFVAPKGSIALDGTSLTVNAVDGTDFDVLLIRHTLEVTTWGERKAG
CCEEEEECCHHHHHHHHCCCCCEEECCCEEEEEEECCCCEEEEEEEEEEEEEECCCCCCC
DFVNFEVDTMARYAARLAEFPSA
CEEEEEHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFTGIVTDVGTVESVSPLKEGIRLRVATAYDPATIDMGASISHSGICLTVTGLPDEGSNG
CCCEEECCCCCCCCHHHHHCCEEEEEEECCCCEEEECCCCCCCCCEEEEEEECCCCCCCC
RWFEVEAWEEALRLTTIGTWREGSRINLERSLKIGDELGGHIVSGHVDGKAEILSVTSEG
CEEEEHHHHHHEEEEEEECCCCCCEEEEEEEEECCCCCCCEEEEEECCCCEEEEEEECCC
DATRYRLRAPEHLAKFVAPKGSIALDGTSLTVNAVDGTDFDVLLIRHTLEVTTWGERKAG
CCEEEEECCHHHHHHHHCCCCCEEECCCEEEEEEECCCCEEEEEEEEEEEEEECCCCCCC
DFVNFEVDTMARYAARLAEFPSA
CEEEEEHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8144477 [H]