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The map label for this gene is ribD [H]

Identifier: 209548782

GI number: 209548782

Start: 1190345

End: 1191559

Strand: Direct

Name: ribD [H]

Synonym: Rleg2_1179

Alternate gene names: 209548782

Gene position: 1190345-1191559 (Clockwise)

Preceding gene: 209548781

Following gene: 209548783

Centisome position: 26.23

GC content: 65.84

Gene sequence:

>1215_bases
ATGAGCGTCACGCCGCATGACGAGAGTTTCATGGCGGCGGCGATCCGCCTGTCGCGCCGGCATCTCGGCCGCACCGCCAC
CAACCCCTCCGTCGGTTGCCTGATCGTCAGGGACGGTGTCGTCGTCGGCCAGGCTGTCACCGCCGTCGGCGGCCGCCCGC
ATGCCGAGCCGCAGGCGCTCGCCGAAGCAGGCGCTGCTGCCCGCGGCGCCACAGCCTATGTGACGCTCGAACCCTGCTCG
CATCACGGTAAGACCCCCCCTTGCGCCGAGGCGCTGATCGCCTATGGCGTTGCCCGTGTCGTCATCAGCGTCACCGATCC
CGATCCACGCGTCTCCGGCCGTGGTATCGCCATGCTGCGGGAAGCCGGTATCGAGGTGGATGCCGGCGTGCTGGAGGCGG
ATGGACGGCGTTCGCTTGCCGGCTATCTCACCCGCCAGACGAAGAACCGGCCTTATGTGACTCTCAAACTTGCCGTTTCC
GCCGACGGCATGATTGGCCGCGAGGGCGCGGGGCAGGTGGCGATAACCGGTCCGGAGGCCCGCGCCGAGGTTCAGGCGCT
GCGCGCCGAAACCGACGCGATCCTTGTCGGCATCGGCACCGCAATATCAGATGATCCGCTGCTGACGGTTCGGACACCAG
GCCTTGAGGCTCAGTCCCCCATCCGCATCGTGCTCGATCCCTCGCTGGCCCTGCCGCTGACGAGCAAGCTGGTTCAGACG
GCGCGCGATGTCCCGGTGATCGTGGTGGCGAGTGAAGAGATTTCGCCATCAGGGTCAGAGGAAGGGTTATCCCCCTCTGC
CCTGGGAGCTAACCCCCAGCCAATCTCCCCCCTTGTGGGGGAGATGTCCGGCAGGACAGAGGGGGGTGCCACACTCCCCG
CCGCTGCTATGGACCTGGACTCCCGCCGCACCGCTCTCGAAGCCGCCGGTGTCGAGATCGTCTACTGCAATCCCTATCAT
CCGGAAATCCTGCTGCCGGCCTTGGCAACACGCGGTATTTCCTCGCTTCTGGTCGAGGGCGGCGCCAAGACCGCCCGGCT
TTTTCTCGAGGCTGGCCTCGTCGACCGCATTCAGCTTTACCAGGCGCCTGTGGTCATCGGCGAGGGCGGTATTGAATCGC
CGCTTGATGCAACCGACATACCACCGGGTTTTGCCCAGACGGGCACGCAGATGTTCGGCGAAGATCGCCTGGACGAATAC
GAAAGAGGGCTTTGA

Upstream 100 bases:

>100_bases
CGCCTCCGTCTATCGGGATTTCTCGCTTGCCGAGGATTTCGAAAAAGTCATTTCCGAAATCAACGCCAAGATCGCCCGCG
ACCCGCTGGACAGGTGAGCC

Downstream 100 bases:

>100_bases
TGTTTACCGGAATAGTCACCGATGTCGGCACGGTCGAATCCGTTTCCCCGCTGAAGGAAGGCATCCGGCTGCGGGTCGCC
ACCGCCTACGATCCCGCAAC

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MSVTPHDESFMAAAIRLSRRHLGRTATNPSVGCLIVRDGVVVGQAVTAVGGRPHAEPQALAEAGAAARGATAYVTLEPCS
HHGKTPPCAEALIAYGVARVVISVTDPDPRVSGRGIAMLREAGIEVDAGVLEADGRRSLAGYLTRQTKNRPYVTLKLAVS
ADGMIGREGAGQVAITGPEARAEVQALRAETDAILVGIGTAISDDPLLTVRTPGLEAQSPIRIVLDPSLALPLTSKLVQT
ARDVPVIVVASEEISPSGSEEGLSPSALGANPQPISPLVGEMSGRTEGGATLPAAAMDLDSRRTALEAAGVEIVYCNPYH
PEILLPALATRGISSLLVEGGAKTARLFLEAGLVDRIQLYQAPVVIGEGGIESPLDATDIPPGFAQTGTQMFGEDRLDEY
ERGL

Sequences:

>Translated_404_residues
MSVTPHDESFMAAAIRLSRRHLGRTATNPSVGCLIVRDGVVVGQAVTAVGGRPHAEPQALAEAGAAARGATAYVTLEPCS
HHGKTPPCAEALIAYGVARVVISVTDPDPRVSGRGIAMLREAGIEVDAGVLEADGRRSLAGYLTRQTKNRPYVTLKLAVS
ADGMIGREGAGQVAITGPEARAEVQALRAETDAILVGIGTAISDDPLLTVRTPGLEAQSPIRIVLDPSLALPLTSKLVQT
ARDVPVIVVASEEISPSGSEEGLSPSALGANPQPISPLVGEMSGRTEGGATLPAAAMDLDSRRTALEAAGVEIVYCNPYH
PEILLPALATRGISSLLVEGGAKTARLFLEAGLVDRIQLYQAPVVIGEGGIESPLDATDIPPGFAQTGTQMFGEDRLDEY
ERGL
>Mature_403_residues
SVTPHDESFMAAAIRLSRRHLGRTATNPSVGCLIVRDGVVVGQAVTAVGGRPHAEPQALAEAGAAARGATAYVTLEPCSH
HGKTPPCAEALIAYGVARVVISVTDPDPRVSGRGIAMLREAGIEVDAGVLEADGRRSLAGYLTRQTKNRPYVTLKLAVSA
DGMIGREGAGQVAITGPEARAEVQALRAETDAILVGIGTAISDDPLLTVRTPGLEAQSPIRIVLDPSLALPLTSKLVQTA
RDVPVIVVASEEISPSGSEEGLSPSALGANPQPISPLVGEMSGRTEGGATLPAAAMDLDSRRTALEAAGVEIVYCNPYHP
EILLPALATRGISSLLVEGGAKTARLFLEAGLVDRIQLYQAPVVIGEGGIESPLDATDIPPGFAQTGTQMFGEDRLDEYE
RGL

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=244, Percent_Identity=46.7213114754098, Blast_Score=217, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 41842; Mature: 41711

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTPHDESFMAAAIRLSRRHLGRTATNPSVGCLIVRDGVVVGQAVTAVGGRPHAEPQAL
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEECHHHHHCCCCCCCCHHHH
AEAGAAARGATAYVTLEPCSHHGKTPPCAEALIAYGVARVVISVTDPDPRVSGRGIAMLR
HHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCCCCCCCCCHHHH
EAGIEVDAGVLEADGRRSLAGYLTRQTKNRPYVTLKLAVSADGMIGREGAGQVAITGPEA
HCCCEECCCEECCCCCHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCEEEEECCHH
RAEVQALRAETDAILVGIGTAISDDPLLTVRTPGLEAQSPIRIVLDPSLALPLTSKLVQT
HHHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHH
ARDVPVIVVASEEISPSGSEEGLSPSALGANPQPISPLVGEMSGRTEGGATLPAAAMDLD
HCCCCEEEEECCCCCCCCCCCCCCCHHCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHCCC
SRRTALEAAGVEIVYCNPYHPEILLPALATRGISSLLVEGGAKTARLFLEAGLVDRIQLY
HHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHCCHHHHHHH
QAPVVIGEGGIESPLDATDIPPGFAQTGTQMFGEDRLDEYERGL
CCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHCC
>Mature Secondary Structure 
SVTPHDESFMAAAIRLSRRHLGRTATNPSVGCLIVRDGVVVGQAVTAVGGRPHAEPQAL
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEECHHHHHCCCCCCCCHHHH
AEAGAAARGATAYVTLEPCSHHGKTPPCAEALIAYGVARVVISVTDPDPRVSGRGIAMLR
HHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCCCCCCCCCHHHH
EAGIEVDAGVLEADGRRSLAGYLTRQTKNRPYVTLKLAVSADGMIGREGAGQVAITGPEA
HCCCEECCCEECCCCCHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCEEEEECCHH
RAEVQALRAETDAILVGIGTAISDDPLLTVRTPGLEAQSPIRIVLDPSLALPLTSKLVQT
HHHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHH
ARDVPVIVVASEEISPSGSEEGLSPSALGANPQPISPLVGEMSGRTEGGATLPAAAMDLD
HCCCCEEEEECCCCCCCCCCCCCCCHHCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHCCC
SRRTALEAAGVEIVYCNPYHPEILLPALATRGISSLLVEGGAKTARLFLEAGLVDRIQLY
HHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHCCHHHHHHH
QAPVVIGEGGIESPLDATDIPPGFAQTGTQMFGEDRLDEYERGL
CCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]