Click here to switch to the map view.

The map label for this gene is nrdR

Identifier: 209548781

GI number: 209548781

Start: 1189865

End: 1190341

Strand: Direct

Name: nrdR

Synonym: Rleg2_1178

Alternate gene names: 209548781

Gene position: 1189865-1190341 (Clockwise)

Preceding gene: 209548780

Following gene: 209548782

Centisome position: 26.22

GC content: 61.43

Gene sequence:

>477_bases
ATGCGCTGCCCCTATTGCGGTTCGGAAGATACACAGGTTAAAGATTCGCGTCCGGCGGAGGACAATACGTCCATCCGCCG
GCGGCGTATCTGTCCGGATTGCGGCGGCCGCTTCACTACCTTCGAGCGCGTGCAGCTGCGCGAGCTGATGGTCATCAAGA
AGACCGGCCGCAAGGTTCCCTTCGATCGAGACAAGCTGGTGCGCTCCTTCGAAGTGGCACTGCGCAAACGCCCTGTCGAG
CGTGACCGCATCGAGCGCGCCGTGTCCGGCATCGTCCGCCGGCTCGAAAGCTCCGGCGAGACGGAGATCTCCTCCGAACA
GATCGGCCTGCAGGTGCTCGAAGCGATGAAGAGCCTCGACGATGTCGGCTTCGTGCGCTACGCCTCCGTCTATCGGGATT
TCTCGCTTGCCGAGGATTTCGAAAAAGTCATTTCCGAAATCAACGCCAAGATCGCCCGCGACCCGCTGGACAGGTGA

Upstream 100 bases:

>100_bases
CGATGAAGGCAACGCCGCCGTCGAAGCCGCCGTGCGCGGCAAGGTGGTCAACCTCACTGACCGCTTCCCAATGTATGACT
ACATGGGATAAGGAGTAGCG

Downstream 100 bases:

>100_bases
GCCATGAGCGTCACGCCGCATGACGAGAGTTTCATGGCGGCGGCGATCCGCCTGTCGCGCCGGCATCTCGGCCGCACCGC
CACCAACCCCTCCGTCGGTT

Product: NrdR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MRCPYCGSEDTQVKDSRPAEDNTSIRRRRICPDCGGRFTTFERVQLRELMVIKKTGRKVPFDRDKLVRSFEVALRKRPVE
RDRIERAVSGIVRRLESSGETEISSEQIGLQVLEAMKSLDDVGFVRYASVYRDFSLAEDFEKVISEINAKIARDPLDR

Sequences:

>Translated_158_residues
MRCPYCGSEDTQVKDSRPAEDNTSIRRRRICPDCGGRFTTFERVQLRELMVIKKTGRKVPFDRDKLVRSFEVALRKRPVE
RDRIERAVSGIVRRLESSGETEISSEQIGLQVLEAMKSLDDVGFVRYASVYRDFSLAEDFEKVISEINAKIARDPLDR
>Mature_158_residues
MRCPYCGSEDTQVKDSRPAEDNTSIRRRRICPDCGGRFTTFERVQLRELMVIKKTGRKVPFDRDKLVRSFEVALRKRPVE
RDRIERAVSGIVRRLESSGETEISSEQIGLQVLEAMKSLDDVGFVRYASVYRDFSLAEDFEKVISEINAKIARDPLDR

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=42.1768707482993, Blast_Score=117, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_RHIE6 (B3PVB6)

Other databases:

- EMBL:   CP001074
- RefSeq:   YP_001977735.1
- GeneID:   6399666
- GenomeReviews:   CP001074_GR
- KEGG:   rec:RHECIAT_CH0001579
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 18261; Mature: 18261

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPYCGSEDTQVKDSRPAEDNTSIRRRRICPDCGGRFTTFERVQLRELMVIKKTGRKVP
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
FDRDKLVRSFEVALRKRPVERDRIERAVSGIVRRLESSGETEISSEQIGLQVLEAMKSLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
DVGFVRYASVYRDFSLAEDFEKVISEINAKIARDPLDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRCPYCGSEDTQVKDSRPAEDNTSIRRRRICPDCGGRFTTFERVQLRELMVIKKTGRKVP
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
FDRDKLVRSFEVALRKRPVERDRIERAVSGIVRRLESSGETEISSEQIGLQVLEAMKSLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
DVGFVRYASVYRDFSLAEDFEKVISEINAKIARDPLDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA