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The map label for this gene is slt [H]

Identifier: 209548591

GI number: 209548591

Start: 1010724

End: 1012799

Strand: Reverse

Name: slt [H]

Synonym: Rleg2_0988

Alternate gene names: 209548591

Gene position: 1012799-1010724 (Counterclockwise)

Preceding gene: 209548594

Following gene: 209548590

Centisome position: 22.32

GC content: 63.49

Gene sequence:

>2076_bases
ATGAAGAAAGCTGTCCTAATTCTGTCCGCCTTCGGCTTTATTGCCGCCGCGTGGAGCAGCGTAGCGTCGCCGCTTGCCGG
CGAAAGCACGGCCATGCCCGCCGTCAAGCCGCTCGGCTTCATTCCCGAGACAGCCATGCCGGAATCGATCACCACAGGCG
CCATTCCGCGCAATCCCGCAGTCGCGCCCGTCAACGGCGACCTGAAAGCCGGTCTCGATGCACTTTCCGACAAGGACCCG
CGGCTGGCGCTGTCGATCCGCGACAATATGCGCGACGGTACGCTCGATCGCCATATCCTCACCTGGGCGATCGCCGTTTC
CGGATTGAAGGGCGTTCCCTCCCATGAAATCGCCAGTGCTGCGCAGGAGCTCAAGAGCTGGCCGGGCCTGTCGCGGCTGC
GTGCCTATTCCGAACGCGCGCTTTATGACGAAAACCCCGCCCCATCAGCCGTGCTGGCCGCCTTCGGCGATACCGCGCCT
GAGACGATGCAGGGCGCCGTCATCCTCGGCCGGGCGCTGGTTGCAACAGGCAAACAAGCGCAGGCTGCTAAATATATCCG
TAAAGTCTGGCGCGGCGAAGCTCTCGACAAGGCGACCGAGGACCAGATCCTCATCGAATTTTCCGCGCTGTTGACGCCGG
CCGACCATAAGGCACGGATGGACTATCTGATGTATCGCGGCCGGGTGGCTCAGGCCAAACGCTTCGGCGACATGGGCGAG
GCGCAGTCGCTCTACAAGGCATGGTCCGCCGTCGACGCCGAAGCCGGCAATGCCGGCGCGCTGCTTAACGCCGTCGATGC
GAGATGGCGCAGCGATGCTGGCCTGCTGTTTGCGCGCATCGAATATCTGCGCAAGCAGGACAAATATGCCGAGGCTGCGG
CACTGCTGGAACAGATGCCGCCCGAGCGCAGCGAGCTCGTCAATTCCGGCGAGTGGTGGAACGAGCAGCGCATCGTCAGC
CGTGGCCTCGTCGACCAGGGACAGTTCAAGCCTGCCTATCGCATCGTCGCAAACTACGCCGCAACCAGCCCGACGGATAT
CGTCGAGGCGGAATTCCATGCCGGGTGGTACGCGCTTCGCGGCCTGCAGGATCCGGCAACGGCGGAAAAGCACTTCCGCA
AGATCCTCCAGACATCGAACGGGCCGATTTCGGTTTCACGCGCCTGGTATTGGCTGGGACGAGCGGCGGAGGCTGGCGGC
CCGGGCAAATCCAGTGAATTCTATGCGAAGGCTGCGACGTTTCCCGGCACCTTCTATGGCCAGCTCGCAGCAGAACGGCT
GGGGCGAAAGACGCTGAACGTTACCTATCCCTCGCCGAGCACGGCCGACCGGCAAAACTTCCAGGCACGCGAAGCCGTAC
AGGCAATCGCCCGGCTGGAAGCTGCAGGCCATGGATGGCGGGCCGACATTCTCTATCTCGCGCTCGCCGACCAGCTGCAG
AGCCCCGGTGAACTGGCCGTGCTTGCGGCACAGGCCGAGCAATCCGGCGATCATCATCTGTCGCTGCAGATCGGAAAAAT
CGCCTATGGGCGCGGCATCGATGTCGCAGCGCTCGCCTTTCCGGTCGGCGTCATTCCGGCGAATGCCAATATTTCAGGCT
CCGGCAAGGCGCTTGCCTATGCCATCGCCCGTCAGGAAAGCGCCTTCAACCCGGCCGCGGTTTCGGCGGCGAATGCGCGC
GGCCTGCTGCAGCTTCTGCCGGGAACGGCCCAGGCGGTGGCCAAGCGCCACAACATCGCCTATTCGAAAGACAAGCTGAC
GGCCGATGCCGGTTATAACGCCACACTCGGCGCGCATTATCTCGGCGAGCAGATCGACGCCTTCGGCGGCTCCTATATCC
TCACCTTCATCGCCTATAATGCCGGGCCGAAGCGGGTACCGGAATGGATCGGCCGCTACGGCGATCCGCGCGGCAAATCG
ATCGACGAGATCGTCGACTGGATCGAGCGCATCCCCTTCCCCGAAACGCGGAACTACGTGCAGCGGGTGATGGAGAATTA
CGAGGTCTACAAGGCCCGCCTCGGCCAGTCGACCGATATCGAGCGTGACCTCATCGGCGGACGCAGCGCCTCCTGA

Upstream 100 bases:

>100_bases
TTCCGATAGCAGATGTGAATGAATTTTACCTGGTACGGTAAGGTTTCGTTAAGATGCCTCTAGCCAAATGGCAGGGCGTG
TTTTCGTTGCGAGATCCCGG

Downstream 100 bases:

>100_bases
CGCTGTTTGGCGCGGCTCGAAAAGCAGGCTACACCTTCGGGATCAACAACTCTCGAGGGATGCGATGCCGGATACGGATG
CAGGCGGTTTCCAGGAACGA

Product: Lytic transglycosylase

Products: 1,6-Anhydrobond [C]

Alternate protein names: Peptidoglycan lytic exotransglycosylase [H]

Number of amino acids: Translated: 691; Mature: 691

Protein sequence:

>691_residues
MKKAVLILSAFGFIAAAWSSVASPLAGESTAMPAVKPLGFIPETAMPESITTGAIPRNPAVAPVNGDLKAGLDALSDKDP
RLALSIRDNMRDGTLDRHILTWAIAVSGLKGVPSHEIASAAQELKSWPGLSRLRAYSERALYDENPAPSAVLAAFGDTAP
ETMQGAVILGRALVATGKQAQAAKYIRKVWRGEALDKATEDQILIEFSALLTPADHKARMDYLMYRGRVAQAKRFGDMGE
AQSLYKAWSAVDAEAGNAGALLNAVDARWRSDAGLLFARIEYLRKQDKYAEAAALLEQMPPERSELVNSGEWWNEQRIVS
RGLVDQGQFKPAYRIVANYAATSPTDIVEAEFHAGWYALRGLQDPATAEKHFRKILQTSNGPISVSRAWYWLGRAAEAGG
PGKSSEFYAKAATFPGTFYGQLAAERLGRKTLNVTYPSPSTADRQNFQAREAVQAIARLEAAGHGWRADILYLALADQLQ
SPGELAVLAAQAEQSGDHHLSLQIGKIAYGRGIDVAALAFPVGVIPANANISGSGKALAYAIARQESAFNPAAVSAANAR
GLLQLLPGTAQAVAKRHNIAYSKDKLTADAGYNATLGAHYLGEQIDAFGGSYILTFIAYNAGPKRVPEWIGRYGDPRGKS
IDEIVDWIERIPFPETRNYVQRVMENYEVYKARLGQSTDIERDLIGGRSAS

Sequences:

>Translated_691_residues
MKKAVLILSAFGFIAAAWSSVASPLAGESTAMPAVKPLGFIPETAMPESITTGAIPRNPAVAPVNGDLKAGLDALSDKDP
RLALSIRDNMRDGTLDRHILTWAIAVSGLKGVPSHEIASAAQELKSWPGLSRLRAYSERALYDENPAPSAVLAAFGDTAP
ETMQGAVILGRALVATGKQAQAAKYIRKVWRGEALDKATEDQILIEFSALLTPADHKARMDYLMYRGRVAQAKRFGDMGE
AQSLYKAWSAVDAEAGNAGALLNAVDARWRSDAGLLFARIEYLRKQDKYAEAAALLEQMPPERSELVNSGEWWNEQRIVS
RGLVDQGQFKPAYRIVANYAATSPTDIVEAEFHAGWYALRGLQDPATAEKHFRKILQTSNGPISVSRAWYWLGRAAEAGG
PGKSSEFYAKAATFPGTFYGQLAAERLGRKTLNVTYPSPSTADRQNFQAREAVQAIARLEAAGHGWRADILYLALADQLQ
SPGELAVLAAQAEQSGDHHLSLQIGKIAYGRGIDVAALAFPVGVIPANANISGSGKALAYAIARQESAFNPAAVSAANAR
GLLQLLPGTAQAVAKRHNIAYSKDKLTADAGYNATLGAHYLGEQIDAFGGSYILTFIAYNAGPKRVPEWIGRYGDPRGKS
IDEIVDWIERIPFPETRNYVQRVMENYEVYKARLGQSTDIERDLIGGRSAS
>Mature_691_residues
MKKAVLILSAFGFIAAAWSSVASPLAGESTAMPAVKPLGFIPETAMPESITTGAIPRNPAVAPVNGDLKAGLDALSDKDP
RLALSIRDNMRDGTLDRHILTWAIAVSGLKGVPSHEIASAAQELKSWPGLSRLRAYSERALYDENPAPSAVLAAFGDTAP
ETMQGAVILGRALVATGKQAQAAKYIRKVWRGEALDKATEDQILIEFSALLTPADHKARMDYLMYRGRVAQAKRFGDMGE
AQSLYKAWSAVDAEAGNAGALLNAVDARWRSDAGLLFARIEYLRKQDKYAEAAALLEQMPPERSELVNSGEWWNEQRIVS
RGLVDQGQFKPAYRIVANYAATSPTDIVEAEFHAGWYALRGLQDPATAEKHFRKILQTSNGPISVSRAWYWLGRAAEAGG
PGKSSEFYAKAATFPGTFYGQLAAERLGRKTLNVTYPSPSTADRQNFQAREAVQAIARLEAAGHGWRADILYLALADQLQ
SPGELAVLAAQAEQSGDHHLSLQIGKIAYGRGIDVAALAFPVGVIPANANISGSGKALAYAIARQESAFNPAAVSAANAR
GLLQLLPGTAQAVAKRHNIAYSKDKLTADAGYNATLGAHYLGEQIDAFGGSYILTFIAYNAGPKRVPEWIGRYGDPRGKS
IDEIVDWIERIPFPETRNYVQRVMENYEVYKARLGQSTDIERDLIGGRSAS

Specific function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI87082441, Length=141, Percent_Identity=40.4255319148936, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011989
- InterPro:   IPR016026
- InterPro:   IPR008258
- InterPro:   IPR012289
- InterPro:   IPR008939
- InterPro:   IPR000189 [H]

Pfam domain/function: PF01464 SLT [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 74586; Mature: 74586

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS00922 TRANSGLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKAVLILSAFGFIAAAWSSVASPLAGESTAMPAVKPLGFIPETAMPESITTGAIPRNPA
CCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
VAPVNGDLKAGLDALSDKDPRLALSIRDNMRDGTLDRHILTWAIAVSGLKGVPSHEIASA
CCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHH
AQELKSWPGLSRLRAYSERALYDENPAPSAVLAAFGDTAPETMQGAVILGRALVATGKQA
HHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHCCHHHHHHHHHHCCCHH
QAAKYIRKVWRGEALDKATEDQILIEFSALLTPADHKARMDYLMYRGRVAQAKRFGDMGE
HHHHHHHHHHCCCHHCCCCCCCEEEEEHHHCCCCCHHHHHHHHHHHCHHHHHHHCCCCHH
AQSLYKAWSAVDAEAGNAGALLNAVDARWRSDAGLLFARIEYLRKQDKYAEAAALLEQMP
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PERSELVNSGEWWNEQRIVSRGLVDQGQFKPAYRIVANYAATSPTDIVEAEFHAGWYALR
CCHHHHCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCHHHHC
GLQDPATAEKHFRKILQTSNGPISVSRAWYWLGRAAEAGGPGKSSEFYAKAATFPGTFYG
CCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCHHHH
QLAAERLGRKTLNVTYPSPSTADRQNFQAREAVQAIARLEAAGHGWRADILYLALADQLQ
HHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
SPGELAVLAAQAEQSGDHHLSLQIGKIAYGRGIDVAALAFPVGVIPANANISGSGKALAY
CCCCEEEEEECHHCCCCCEEEEEECCEECCCCCCHHHHHHHHEEEECCCCCCCCCCHHHH
AIARQESAFNPAAVSAANARGLLQLLPGTAQAVAKRHNIAYSKDKLTADAGYNATLGAHY
HHHHHCCCCCCHHHHHHCCCHHHHHCCCHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHH
LGEQIDAFGGSYILTFIAYNAGPKRVPEWIGRYGDPRGKSIDEIVDWIERIPFPETRNYV
HHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHH
QRVMENYEVYKARLGQSTDIERDLIGGRSAS
HHHHHHHHHHHHHCCCCCCCHHHHCCCCCCC
>Mature Secondary Structure
MKKAVLILSAFGFIAAAWSSVASPLAGESTAMPAVKPLGFIPETAMPESITTGAIPRNPA
CCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
VAPVNGDLKAGLDALSDKDPRLALSIRDNMRDGTLDRHILTWAIAVSGLKGVPSHEIASA
CCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHH
AQELKSWPGLSRLRAYSERALYDENPAPSAVLAAFGDTAPETMQGAVILGRALVATGKQA
HHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHCCHHHHHHHHHHCCCHH
QAAKYIRKVWRGEALDKATEDQILIEFSALLTPADHKARMDYLMYRGRVAQAKRFGDMGE
HHHHHHHHHHCCCHHCCCCCCCEEEEEHHHCCCCCHHHHHHHHHHHCHHHHHHHCCCCHH
AQSLYKAWSAVDAEAGNAGALLNAVDARWRSDAGLLFARIEYLRKQDKYAEAAALLEQMP
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PERSELVNSGEWWNEQRIVSRGLVDQGQFKPAYRIVANYAATSPTDIVEAEFHAGWYALR
CCHHHHCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCHHHHC
GLQDPATAEKHFRKILQTSNGPISVSRAWYWLGRAAEAGGPGKSSEFYAKAATFPGTFYG
CCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCHHHH
QLAAERLGRKTLNVTYPSPSTADRQNFQAREAVQAIARLEAAGHGWRADILYLALADQLQ
HHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
SPGELAVLAAQAEQSGDHHLSLQIGKIAYGRGIDVAALAFPVGVIPANANISGSGKALAY
CCCCEEEEEECHHCCCCCEEEEEECCEECCCCCCHHHHHHHHEEEECCCCCCCCCCHHHH
AIARQESAFNPAAVSAANARGLLQLLPGTAQAVAKRHNIAYSKDKLTADAGYNATLGAHY
HHHHHCCCCCCHHHHHHCCCHHHHHCCCHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHH
LGEQIDAFGGSYILTFIAYNAGPKRVPEWIGRYGDPRGKSIDEIVDWIERIPFPETRNYV
HHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHH
QRVMENYEVYKARLGQSTDIERDLIGGRSAS
HHHHHHHHHHHHHCCCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]