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The map label for this gene is 209548578

Identifier: 209548578

GI number: 209548578

Start: 995189

End: 996553

Strand: Direct

Name: 209548578

Synonym: Rleg2_0975

Alternate gene names: NA

Gene position: 995189-996553 (Clockwise)

Preceding gene: 209548577

Following gene: 209548587

Centisome position: 21.93

GC content: 65.35

Gene sequence:

>1365_bases
ATGACCGATCTTTCAGAAGGCAATGCCTTTCTCACCGGCTGGTTGCCGGGCGTCTTCATCAGGACGGCGGCGCCGATCGT
CGCGATCACCACCGTCAACGGCCTCTTCACCGTCGTCGACGCCTATTTCCTCGGCGCCTATGTCGGCCCCGACGCGCTCT
CCGCCGTCAGCCTGATCTTCCCGGGGCTGATGCTGCTGATCGCCCTGCAATCGCTCGTCTCGAACGGCATGGCGAGCATC
CTCGCCCGCCGGCTCGGGGCCGGCGATCGCCGGGGCGCGGGCCGGGTATTTGCCGGGGCCCATATGCTGGCGCTGGCCGT
CACGCTCGTCCTCAACATCCTCTACTGGACCCTGGGGCGGCAGATCATCGACGCCGGTGCCGGCACGGCCGCCGTGGCCG
AGGGCGCCAGGTTGTTCATGGGCGCGATGATCGCCTTTGCGCCAGTGAGCTTCTTCCTGTCGCTGCATCTCGACGGATTG
CGCTGCGAGGGCAAGATCGGCTTCATGACGCTGGTGACGCTGACGGCCTCGCTGCTCAACATCTTCGCCAACTGGCTGTT
CATGGCGGTGATGCATTGGGGCGTGCTCGGTTCGGCTGCCGGCTCCATCGCCGCGCAATTCGTCTGTCTCGCCGCCGTGC
TCGCCTATCGCTGGCGCCGGCCGGCGGCACTCAGGCCTTACCGAGGATTCGCCCTTGCCGAATGGCGCGGCATCGTCGCC
TTCGGCGCGCCGATGAGCCTTGGCTTCATCGGCATATCGCTGGCATCCGCCGCCATTCTCGTCAATATCTCGCTCTGGAG
CACGCATGATCATGTCGCGACGGTCGCCGCCTACGGCATCATCACCCGGATCATGACCTTCACCTATCTGCCGCTGCTCG
GTCTCAGCATCGCCTTGCAGACGATTGCCGGCAACAATCACGGCGCCGGCCTTGGTCTTCGCGTCGGCCGCAGCCTGCAG
ATCGCCATGCTTGCGGCGCTCGTCTATTGCAGTCTGGTCGAGATCGCCGTCGAACTGCTGGCCGGCCGTCTCGGCGCCGT
CTTCGTCGCCGATCCTGCCATTGTCGCCGAGGTCAGGCGAATCCTGCCCTGGACGATCGGCGCCTATTTTCTCTTCGGGC
AGATGCTGATCCTGTCGTCCTATTTCCAGTCGATCGGCGATGCGTCGCGCGCGGCGATCTTCGGCCTGTCGCGGCCTTAT
CTCTTCACCCTGCCGCTCACCTTCCTGCTGCCCTTCGTCTTCGGCGAGCAGGGGATCTGGATGGTGCCGGTCTTTGCCGA
GGCAGGCATGTTCATCCTGGCCTTTCTGGTGCTGTCGCAGAATGCCAGGCACCGCGGCTGGCGGTACGGGCTTCTGCCCG
CCTGA

Upstream 100 bases:

>100_bases
GGTGCTCGATCTCTAAATCATTTTTGATTCCCTTTGAGGCCGCCTGAATCCGGATGTTTTCAACCCGGATCGGACCTCGC
CATCCCGCACGGATTTTTCT

Downstream 100 bases:

>100_bases
ATCGTAATAGCCGCGCTCGGGAGCGCGGCTATTACCCGATGCCGTCTATTCCTTGCCCGCCGAAGCGGCCGCTGTCGCGG
CGTCAGCCTCGTTCAGCGCC

Product: multi antimicrobial extrusion protein MatE

Products: NA

Alternate protein names: Na+ Driven Multidrug Efflux Pump; Multi Antimicrobial Extrusion Protein MatE; Multi Anti Extrusion Protein MatE; Na+-Driven Multidrug Efflux Pump; MOP/MATE Family Multidrug-Resistance Efflux Pump; Multidrug Efflux Pump VmrA; DNA Damage-Inducible Protein; Drug/Sodium Antiporter; C-5 Cytosine-Specific DNA Methylase; DinF Protein; Na+-Driven Multidrug Resistance Efflux Pump Protein; Cation Efflux Pump; MATE Efflux Family Protein Authentic Frameshift; Mate Efflux Family Protein; Na+ Driven Multidrug Efflux Protein; MatE Family Transporter; Integral Membrane Protein; Na+-Driven Multidrug Efflux Pump NorM; MatE Family Transport-Related Membrane Protein; Multidrug Efflux Protein MatE Family; Cation Transport Related Membrane Protein; Multi Anti Extrusion Protein MatE Family Protein

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MTDLSEGNAFLTGWLPGVFIRTAAPIVAITTVNGLFTVVDAYFLGAYVGPDALSAVSLIFPGLMLLIALQSLVSNGMASI
LARRLGAGDRRGAGRVFAGAHMLALAVTLVLNILYWTLGRQIIDAGAGTAAVAEGARLFMGAMIAFAPVSFFLSLHLDGL
RCEGKIGFMTLVTLTASLLNIFANWLFMAVMHWGVLGSAAGSIAAQFVCLAAVLAYRWRRPAALRPYRGFALAEWRGIVA
FGAPMSLGFIGISLASAAILVNISLWSTHDHVATVAAYGIITRIMTFTYLPLLGLSIALQTIAGNNHGAGLGLRVGRSLQ
IAMLAALVYCSLVEIAVELLAGRLGAVFVADPAIVAEVRRILPWTIGAYFLFGQMLILSSYFQSIGDASRAAIFGLSRPY
LFTLPLTFLLPFVFGEQGIWMVPVFAEAGMFILAFLVLSQNARHRGWRYGLLPA

Sequences:

>Translated_454_residues
MTDLSEGNAFLTGWLPGVFIRTAAPIVAITTVNGLFTVVDAYFLGAYVGPDALSAVSLIFPGLMLLIALQSLVSNGMASI
LARRLGAGDRRGAGRVFAGAHMLALAVTLVLNILYWTLGRQIIDAGAGTAAVAEGARLFMGAMIAFAPVSFFLSLHLDGL
RCEGKIGFMTLVTLTASLLNIFANWLFMAVMHWGVLGSAAGSIAAQFVCLAAVLAYRWRRPAALRPYRGFALAEWRGIVA
FGAPMSLGFIGISLASAAILVNISLWSTHDHVATVAAYGIITRIMTFTYLPLLGLSIALQTIAGNNHGAGLGLRVGRSLQ
IAMLAALVYCSLVEIAVELLAGRLGAVFVADPAIVAEVRRILPWTIGAYFLFGQMLILSSYFQSIGDASRAAIFGLSRPY
LFTLPLTFLLPFVFGEQGIWMVPVFAEAGMFILAFLVLSQNARHRGWRYGLLPA
>Mature_453_residues
TDLSEGNAFLTGWLPGVFIRTAAPIVAITTVNGLFTVVDAYFLGAYVGPDALSAVSLIFPGLMLLIALQSLVSNGMASIL
ARRLGAGDRRGAGRVFAGAHMLALAVTLVLNILYWTLGRQIIDAGAGTAAVAEGARLFMGAMIAFAPVSFFLSLHLDGLR
CEGKIGFMTLVTLTASLLNIFANWLFMAVMHWGVLGSAAGSIAAQFVCLAAVLAYRWRRPAALRPYRGFALAEWRGIVAF
GAPMSLGFIGISLASAAILVNISLWSTHDHVATVAAYGIITRIMTFTYLPLLGLSIALQTIAGNNHGAGLGLRVGRSLQI
AMLAALVYCSLVEIAVELLAGRLGAVFVADPAIVAEVRRILPWTIGAYFLFGQMLILSSYFQSIGDASRAAIFGLSRPYL
FTLPLTFLLPFVFGEQGIWMVPVFAEAGMFILAFLVLSQNARHRGWRYGLLPA

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 48412; Mature: 48281

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLSEGNAFLTGWLPGVFIRTAAPIVAITTVNGLFTVVDAYFLGAYVGPDALSAVSLIF
CCCCCCCCEEEEECHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
PGLMLLIALQSLVSNGMASILARRLGAGDRRGAGRVFAGAHMLALAVTLVLNILYWTLGR
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QIIDAGAGTAAVAEGARLFMGAMIAFAPVSFFLSLHLDGLRCEGKIGFMTLVTLTASLLN
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHH
IFANWLFMAVMHWGVLGSAAGSIAAQFVCLAAVLAYRWRRPAALRPYRGFALAEWRGIVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCEEE
FGAPMSLGFIGISLASAAILVNISLWSTHDHVATVAAYGIITRIMTFTYLPLLGLSIALQ
ECCCHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIAGNNHGAGLGLRVGRSLQIAMLAALVYCSLVEIAVELLAGRLGAVFVADPAIVAEVRR
HHCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHH
ILPWTIGAYFLFGQMLILSSYFQSIGDASRAAIFGLSRPYLFTLPLTFLLPFVFGEQGIW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEECCCCCHHHHHHHHHHHHHHCCCCCE
MVPVFAEAGMFILAFLVLSQNARHRGWRYGLLPA
EEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDLSEGNAFLTGWLPGVFIRTAAPIVAITTVNGLFTVVDAYFLGAYVGPDALSAVSLIF
CCCCCCCEEEEECHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
PGLMLLIALQSLVSNGMASILARRLGAGDRRGAGRVFAGAHMLALAVTLVLNILYWTLGR
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QIIDAGAGTAAVAEGARLFMGAMIAFAPVSFFLSLHLDGLRCEGKIGFMTLVTLTASLLN
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHH
IFANWLFMAVMHWGVLGSAAGSIAAQFVCLAAVLAYRWRRPAALRPYRGFALAEWRGIVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCEEE
FGAPMSLGFIGISLASAAILVNISLWSTHDHVATVAAYGIITRIMTFTYLPLLGLSIALQ
ECCCHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIAGNNHGAGLGLRVGRSLQIAMLAALVYCSLVEIAVELLAGRLGAVFVADPAIVAEVRR
HHCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHH
ILPWTIGAYFLFGQMLILSSYFQSIGDASRAAIFGLSRPYLFTLPLTFLLPFVFGEQGIW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEECCCCCHHHHHHHHHHHHHHCCCCCE
MVPVFAEAGMFILAFLVLSQNARHRGWRYGLLPA
EEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA