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The map label for this gene is czcD [H]

Identifier: 209548457

GI number: 209548457

Start: 869822

End: 870814

Strand: Direct

Name: czcD [H]

Synonym: Rleg2_0854

Alternate gene names: 209548457

Gene position: 869822-870814 (Clockwise)

Preceding gene: 209548456

Following gene: 209548458

Centisome position: 19.17

GC content: 64.45

Gene sequence:

>993_bases
ATGAGTACCGGGATCGAGAATGCTGGAGCAGACGCGCTGGAACATGACCATATCTTCCTCGGCGCCGATCACGCGGTGAA
CGAGCGGCGCATCTGGCTGGTGATCGCGCTGACGGCGGTGATGATGGTGGCGGAAATCGCCGCCGGCACCGCCTATGGCT
CGATGGCGCTGCTCGCTGATGGCTGGCATATGTCGACCCATGCCAGCGCGCTTTTGATTTCGGCGCTCGCCTATCTCTTC
GCCCGCAAGCAGGCGCGCAATCCGCGTTTCACCTTCGGCACCGGCAAGCTCGGCGATCTCGCCGGCTTCGCCAGCGCCAT
CATTCTTGCGCTGATCGCCCTGCTGATGGCCTGGGAAAGCTGGCTGCGCCTTTCAAATCCGGTGCCGATCGGTTTCGCCC
AGGCAATCGCCGTTGCGGTGATCGGCCTTGCCGTCAATCTCGTCAGCGCCTGGCTGCTTGGCGGCGGCCACGCGCATGGC
CATCACGCGCATGGTCATCATGCGCACCATCACGGCGATCATGCCCATCACGGTCATGGTGATCACGCCCACGATCATCA
CGGAAAGCCCGGCGATAACAATATCCGCGCCGCCTATCTGCATGTCATCGCCGATGCCATGACCTCCGTGCTCGCCATCG
CGGCGCTGACCCTCGGCAGCCTCTACGGCTGGCTCTGGCTCGACCCGATCATGGGCATCGTCGGTGGCCTGGTTATCGCC
AACTGGTCCTGGAGCCTGATGCGATCCTCCGGCGGCGTCCTTCTCGACGTCGTGCCGCACGGCGAGACACTGCCGGCGGA
AATCCGCCACGCGATCGAGACGGAGGAGGATCGGATCACCGATCTGCATGTCTGGCAGGTCGGCCCCGGCCATCACGCCG
CCATCGTCGCCGTCGTCACCTCGACGCCGCGCGAACCGGCTTTCTACAAGGGCAGGCTTTCGGCGCTGACGGAATTGTCG
CATGTGACCGTCGAGGTTACGCGCGCGGCGTAA

Upstream 100 bases:

>100_bases
TGAATGCCGAGGACGACGCCGCCAGGGCCGAGGCGGTCGAGGAAATATCGGAAGTCTTGCGAACCTATATCCGCTGAGTG
CCGTGACGAAGGAGCCTGTA

Downstream 100 bases:

>100_bases
TCGCGGCGGCGGCAACAAGGTTGCTCGGCGGACGACGAAGTCGCCGCGGGGACGAGATGCCGCCGCAATCGCGCCTTAGC
TCTGTCCTCCCCACCGCCGG

Product: cation diffusion facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MSTGIENAGADALEHDHIFLGADHAVNERRIWLVIALTAVMMVAEIAAGTAYGSMALLADGWHMSTHASALLISALAYLF
ARKQARNPRFTFGTGKLGDLAGFASAIILALIALLMAWESWLRLSNPVPIGFAQAIAVAVIGLAVNLVSAWLLGGGHAHG
HHAHGHHAHHHGDHAHHGHGDHAHDHHGKPGDNNIRAAYLHVIADAMTSVLAIAALTLGSLYGWLWLDPIMGIVGGLVIA
NWSWSLMRSSGGVLLDVVPHGETLPAEIRHAIETEEDRITDLHVWQVGPGHHAAIVAVVTSTPREPAFYKGRLSALTELS
HVTVEVTRAA

Sequences:

>Translated_330_residues
MSTGIENAGADALEHDHIFLGADHAVNERRIWLVIALTAVMMVAEIAAGTAYGSMALLADGWHMSTHASALLISALAYLF
ARKQARNPRFTFGTGKLGDLAGFASAIILALIALLMAWESWLRLSNPVPIGFAQAIAVAVIGLAVNLVSAWLLGGGHAHG
HHAHGHHAHHHGDHAHHGHGDHAHDHHGKPGDNNIRAAYLHVIADAMTSVLAIAALTLGSLYGWLWLDPIMGIVGGLVIA
NWSWSLMRSSGGVLLDVVPHGETLPAEIRHAIETEEDRITDLHVWQVGPGHHAAIVAVVTSTPREPAFYKGRLSALTELS
HVTVEVTRAA
>Mature_329_residues
STGIENAGADALEHDHIFLGADHAVNERRIWLVIALTAVMMVAEIAAGTAYGSMALLADGWHMSTHASALLISALAYLFA
RKQARNPRFTFGTGKLGDLAGFASAIILALIALLMAWESWLRLSNPVPIGFAQAIAVAVIGLAVNLVSAWLLGGGHAHGH
HAHGHHAHHHGDHAHHGHGDHAHDHHGKPGDNNIRAAYLHVIADAMTSVLAIAALTLGSLYGWLWLDPIMGIVGGLVIAN
WSWSLMRSSGGVLLDVVPHGETLPAEIRHAIETEEDRITDLHVWQVGPGHHAAIVAVVTSTPREPAFYKGRLSALTELSH
VTVEVTRAA

Specific function: Involved in divalent cation and potassium homeostasis in the cell. Catalyzes the active efflux of zinc, cadmium and cobalt, in exchange for potassium and H(+) ions [H]

COG id: COG1230

COG function: function code P; Co/Zn/Cd efflux system component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily [H]

Homologues:

Organism=Homo sapiens, GI20070323, Length=323, Percent_Identity=26.9349845201238, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI222080086, Length=267, Percent_Identity=26.2172284644195, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI40255009, Length=267, Percent_Identity=26.2172284644195, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI21359890, Length=271, Percent_Identity=25.830258302583, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1786966, Length=266, Percent_Identity=34.2105263157895, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI32564488, Length=347, Percent_Identity=28.8184438040346, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI193210990, Length=263, Percent_Identity=25.8555133079848, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17555794, Length=295, Percent_Identity=27.7966101694915, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17555796, Length=279, Percent_Identity=28.3154121863799, Blast_Score=68, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6320411, Length=218, Percent_Identity=25.6880733944954, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323899, Length=192, Percent_Identity=28.125, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24656728, Length=296, Percent_Identity=27.3648648648649, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24656724, Length=296, Percent_Identity=27.3648648648649, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24656720, Length=296, Percent_Identity=27.3648648648649, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24656715, Length=296, Percent_Identity=27.3648648648649, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21357035, Length=296, Percent_Identity=27.3648648648649, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24645863, Length=301, Percent_Identity=24.9169435215947, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 35127; Mature: 34995

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTGIENAGADALEHDHIFLGADHAVNERRIWLVIALTAVMMVAEIAAGTAYGSMALLAD
CCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
GWHMSTHASALLISALAYLFARKQARNPRFTFGTGKLGDLAGFASAIILALIALLMAWES
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
WLRLSNPVPIGFAQAIAVAVIGLAVNLVSAWLLGGGHAHGHHAHGHHAHHHGDHAHHGHG
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
DHAHDHHGKPGDNNIRAAYLHVIADAMTSVLAIAALTLGSLYGWLWLDPIMGIVGGLVIA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NWSWSLMRSSGGVLLDVVPHGETLPAEIRHAIETEEDRITDLHVWQVGPGHHAAIVAVVT
CCCHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEEEEE
STPREPAFYKGRLSALTELSHVTVEVTRAA
CCCCCCCHHHHHHHHHHHHHHEEEEEEECC
>Mature Secondary Structure 
STGIENAGADALEHDHIFLGADHAVNERRIWLVIALTAVMMVAEIAAGTAYGSMALLAD
CCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
GWHMSTHASALLISALAYLFARKQARNPRFTFGTGKLGDLAGFASAIILALIALLMAWES
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
WLRLSNPVPIGFAQAIAVAVIGLAVNLVSAWLLGGGHAHGHHAHGHHAHHHGDHAHHGHG
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
DHAHDHHGKPGDNNIRAAYLHVIADAMTSVLAIAALTLGSLYGWLWLDPIMGIVGGLVIA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NWSWSLMRSSGGVLLDVVPHGETLPAEIRHAIETEEDRITDLHVWQVGPGHHAAIVAVVT
CCCHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEEEEE
STPREPAFYKGRLSALTELSHVTVEVTRAA
CCCCCCCHHHHHHHHHHHHHHEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA