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The map label for this gene is higA [H]

Identifier: 209548379

GI number: 209548379

Start: 793353

End: 793760

Strand: Direct

Name: higA [H]

Synonym: Rleg2_0775

Alternate gene names: 209548379

Gene position: 793353-793760 (Clockwise)

Preceding gene: 209548378

Following gene: 209548383

Centisome position: 17.48

GC content: 58.09

Gene sequence:

>408_bases
ATGAGCGCACTTGTAAAACTGGTAAGCGAGCACTGGACGCATGTGGCCCCGCTTCTTGCCATGCCGGCCGATGAAGCTGA
ATATGATCATCTTGTGGAGCAGCTTGACGAGATTCTCGCGGAAGTCGGCGACGATGAGGATCATCCCCTGGCGTTGCTTG
CATCGCGCATGGGAGACCTTGTCGAGGCCTATGACCAGCAAAACCGCCCAATGCCTCCCGGGACCGGAGCCGATGCGCTG
CGTTATATCATGGAGGAGCGGGGCCTTGGCCAGTCCGAACTGCCGGAGGTTGGCGCTCAATCCGTCGTATCCGAGATCTT
GAGCGGGAAACGACAAATCAACGTTCGACAGGCGCGCGCCTTGAGCGAGCGGTTTCTCATCCCGGCATCGGTATTTCTAT
CGCTTTGA

Upstream 100 bases:

>100_bases
GCCTGATTGCGATGGTGCACTACAGATTCAAGAAGGTCTATATTCAGCGGATTATGGATCACGCGGAATACGACAAAGGA
GCATGGAAGGGTCAAGCCTG

Downstream 100 bases:

>100_bases
CGATGGACATACAGTGTTGAATTCCAGGACATCCCCGCGACAAGCGACGACAGCTCTCTAAAGCGCGTCGCATCAAACTT
GATTCATGCGACGCGCTTTA

Product: transcription regulator with HTH domain

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 135; Mature: 134

Protein sequence:

>135_residues
MSALVKLVSEHWTHVAPLLAMPADEAEYDHLVEQLDEILAEVGDDEDHPLALLASRMGDLVEAYDQQNRPMPPGTGADAL
RYIMEERGLGQSELPEVGAQSVVSEILSGKRQINVRQARALSERFLIPASVFLSL

Sequences:

>Translated_135_residues
MSALVKLVSEHWTHVAPLLAMPADEAEYDHLVEQLDEILAEVGDDEDHPLALLASRMGDLVEAYDQQNRPMPPGTGADAL
RYIMEERGLGQSELPEVGAQSVVSEILSGKRQINVRQARALSERFLIPASVFLSL
>Mature_134_residues
SALVKLVSEHWTHVAPLLAMPADEAEYDHLVEQLDEILAEVGDDEDHPLALLASRMGDLVEAYDQQNRPMPPGTGADALR
YIMEERGLGQSELPEVGAQSVVSEILSGKRQINVRQARALSERFLIPASVFLSL

Specific function: Part of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin [H]

COG id: COG5499

COG function: function code K; Predicted transcription regulator containing HTH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH cro/C1-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789464, Length=130, Percent_Identity=33.0769230769231, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001387
- InterPro:   IPR010982 [H]

Pfam domain/function: PF01381 HTH_3 [H]

EC number: NA

Molecular weight: Translated: 14846; Mature: 14715

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: PS50943 HTH_CROC1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALVKLVSEHWTHVAPLLAMPADEAEYDHLVEQLDEILAEVGDDEDHPLALLASRMGDL
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
VEAYDQQNRPMPPGTGADALRYIMEERGLGQSELPEVGAQSVVSEILSGKRQINVRQARA
HHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LSERFLIPASVFLSL
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
SALVKLVSEHWTHVAPLLAMPADEAEYDHLVEQLDEILAEVGDDEDHPLALLASRMGDL
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
VEAYDQQNRPMPPGTGADALRYIMEERGLGQSELPEVGAQSVVSEILSGKRQINVRQARA
HHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LSERFLIPASVFLSL
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]