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The map label for this gene is yieH [H]

Identifier: 209548243

GI number: 209548243

Start: 663179

End: 663868

Strand: Reverse

Name: yieH [H]

Synonym: Rleg2_0637

Alternate gene names: 209548243

Gene position: 663868-663179 (Counterclockwise)

Preceding gene: 209548244

Following gene: 209548241

Centisome position: 14.63

GC content: 62.61

Gene sequence:

>690_bases
ATGAACGGCTTCGATCTCATTATCTTCGATTGCGACGGCGTGCTCGTCGATTCCGAAATCATCGCCGCAGAAGTCGAATC
CGCGCTTCTGACGGAGGCGGGATATCCGATCGGCGTCGAGGAAATGGGCGAACGTTTCGCCGGCATGACATGGCGCAACA
TCCTGCTGCAGATCGAGCGCGAAGCGAGCATTCCGTTTTCGGCCTCGCTGCTTGAGAAGTCCGAGCAACTGCTCGACACC
AGGCTGGCAAATGACGTCAAGGCCATTCCGGGCGTCGAATTCGCCGTCTCAAGGCTCTCGATGAAGCGCTGCATCTGCTC
GAATTCGAGCAGCAAGCGGCTCGACATGATGCTCGGCAAGGTGGGGCTGAAGCCGCTGTTTGCCCCCAATATCTTTTCCG
CCAAGGATCTCGGCCCCGACCGGGCCAAGCCGAAGCCCGACATCTTCCTGCACGGCGCAAGCCAGATGGGTGTCTCGCCC
GACAAGGTGGTCGTCGTCGAGGATTCCGTGCACGGCGTGCATGCGGCGCGCGCCGCCGGCATGCGCGTCATCGGCTTCAC
CGGCGCCTCGCACAGCTATCCCGCCCATGCCGACAAGCTGACCGATGCCGGCGCCGAAACGGCGATCTCCCGCATGAACG
ACCTGCCTGGTGTCGTCGCCGCGCTTGCGGCCTGGGAAGGCGTTCTCTAG

Upstream 100 bases:

>100_bases
ATCGCAGCCATGCTTGAGATCCGGTTGAGCTTTGGGCGGGCATCGTGTAAAGCCGCTGCATCCCCGGACAAGACCCAGAT
TTCCAGCAAGGCGTGAACAT

Downstream 100 bases:

>100_bases
GACCTTAGGCGCTGGGCCGCCATCGCGCCCGCCCTTTTGCGAGGAACCGGGCAAATAACAGGCGGCAACCCCAATAATCC
GCTGCCCATTTCGCTATTTG

Product: HAD-superfamily hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MNGFDLIIFDCDGVLVDSEIIAAEVESALLTEAGYPIGVEEMGERFAGMTWRNILLQIEREASIPFSASLLEKSEQLLDT
RLANDVKAIPGVEFAVSRLSMKRCICSNSSSKRLDMMLGKVGLKPLFAPNIFSAKDLGPDRAKPKPDIFLHGASQMGVSP
DKVVVVEDSVHGVHAARAAGMRVIGFTGASHSYPAHADKLTDAGAETAISRMNDLPGVVAALAAWEGVL

Sequences:

>Translated_229_residues
MNGFDLIIFDCDGVLVDSEIIAAEVESALLTEAGYPIGVEEMGERFAGMTWRNILLQIEREASIPFSASLLEKSEQLLDT
RLANDVKAIPGVEFAVSRLSMKRCICSNSSSKRLDMMLGKVGLKPLFAPNIFSAKDLGPDRAKPKPDIFLHGASQMGVSP
DKVVVVEDSVHGVHAARAAGMRVIGFTGASHSYPAHADKLTDAGAETAISRMNDLPGVVAALAAWEGVL
>Mature_229_residues
MNGFDLIIFDCDGVLVDSEIIAAEVESALLTEAGYPIGVEEMGERFAGMTWRNILLQIEREASIPFSASLLEKSEQLLDT
RLANDVKAIPGVEFAVSRLSMKRCICSNSSSKRLDMMLGKVGLKPLFAPNIFSAKDLGPDRAKPKPDIFLHGASQMGVSP
DKVVVVEDSVHGVHAARAAGMRVIGFTGASHSYPAHADKLTDAGAETAISRMNDLPGVVAALAAWEGVL

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates phosphoenolpyruvate and AMP [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1790151, Length=202, Percent_Identity=29.2079207920792, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789046, Length=180, Percent_Identity=30.5555555555556, Blast_Score=67, Evalue=1e-12,
Organism=Drosophila melanogaster, GI20129151, Length=185, Percent_Identity=29.7297297297297, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI116008157, Length=185, Percent_Identity=31.3513513513514, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 24438; Mature: 24438

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGFDLIIFDCDGVLVDSEIIAAEVESALLTEAGYPIGVEEMGERFAGMTWRNILLQIER
CCCCEEEEEECCCEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHCC
EASIPFSASLLEKSEQLLDTRLANDVKAIPGVEFAVSRLSMKRCICSNSSSKRLDMMLGK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
VGLKPLFAPNIFSAKDLGPDRAKPKPDIFLHGASQMGVSPDKVVVVEDSVHGVHAARAAG
HCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHCCCCCCEEEEEECCCCHHHHHHHCC
MRVIGFTGASHSYPAHADKLTDAGAETAISRMNDLPGVVAALAAWEGVL
EEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MNGFDLIIFDCDGVLVDSEIIAAEVESALLTEAGYPIGVEEMGERFAGMTWRNILLQIER
CCCCEEEEEECCCEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHCC
EASIPFSASLLEKSEQLLDTRLANDVKAIPGVEFAVSRLSMKRCICSNSSSKRLDMMLGK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
VGLKPLFAPNIFSAKDLGPDRAKPKPDIFLHGASQMGVSPDKVVVVEDSVHGVHAARAAG
HCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHCCCCCCEEEEEECCCCHHHHHHHCC
MRVIGFTGASHSYPAHADKLTDAGAETAISRMNDLPGVVAALAAWEGVL
EEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]