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The map label for this gene is dnaJ2 [H]

Identifier: 209548198

GI number: 209548198

Start: 618443

End: 619663

Strand: Reverse

Name: dnaJ2 [H]

Synonym: Rleg2_0592

Alternate gene names: 209548198

Gene position: 619663-618443 (Counterclockwise)

Preceding gene: 209548199

Following gene: 209548197

Centisome position: 13.66

GC content: 66.75

Gene sequence:

>1221_bases
ATGCGCGATCCTTATAAAATTCTGGGCGTCAAGCGCGACGCGGCAGCGGACGAGATCAAGGCGGCCTGGCGCAACATGGC
CAAGTCCGCCCATCCCGACCACAATCAGGGTGACCCGACGGCAACGGCCCGGTTCGCCGAGATCGGCCGCGCCTATGAAA
CGCTGAAGGACCCGCGCAAACGCAGCCTGTTCGACAATGCCGTGCGGATGGCGGAAGCCAAGAAGAACGAACAGACGATC
ATGCAGCAGCGCCAGGCGGCGCGTGAGGCTGCCGTGCGCGCCAAGGCGGCGCAGGCCAATGCTGAGCGGGTGATGGAAGA
GCTTGCCCGCGCCGCCCAGAAGGCCGCCGCCGACGGCTCCAGACAACAGGCGGGATCGGCCGAGCCCGCCGACGAGATGG
TCGATCGCATTTTCGGCGCCCAGGCCCGCGCTGCGGCCGGCGGCCAGGCGCAGGCTCGCGCGCACCAGGCGCAATACCAG
CAGGCCCAGAGCCAGCAGACACAGAATCAACAGGCCCAGAACCAGCAGGCCCAGAACCAACAGGCGAGCGAGGCAGGCAG
GCGCGTGGATGGCGACGCCACCGAGGGTGACACCAAGAGCGACGAGGAGGCCGGCGAGGCTGGGCCGAATGCCGGCGCCA
ACCTGCCGCTGCCGCTCAGCATCCTGACATCCCTGGTGCGCCGCTTCACCGGCGCCAAGGATACCGGCCTGGAAAAAGCA
CCCGACGAGGTGGCGACGGCGACGGTGACGATCGACGACGTGCTGAAGAGCGGCTGGATCACCGCGTCACTGCCGGAGGG
CCGCGAGATCGGCTTCGCATTGCCGGCCGGCACAAGGGATGGTCACGAGCTGCGGCTCAAGGGACAGGGCTTCAAGCTGC
CGGGCATGCAGCGCGGCGATGCCGTCATCAACATTCGCATTGCGCCCGATCCGCGCTTCACGGTGGACGGTTTCGATCTG
CATGCCGTGCTGCCGCTCAGCATCGAAAATGCCGTTCTCGGCACCGAGGCGCGCATCGAGGGACCGAGCGGGCCGCTCGA
CATTACCATCCCCGCCTGGTCGGGCTCGGACAAGACGATCAAGATCCCCGGCCAGGGATTGCCCCGCGAAGAGGGCGGCA
GAGGCGATCTCGTCGTCGAATTGCGCATTATCCTGTGGGAAAAGCCCGACGACAAAGTCACCGATCTCATGCGGAGCATG
CGCGAAGGCCTGTTCCTGTGA

Upstream 100 bases:

>100_bases
GCGGTGGGGCGGCGCGAATTGTTATTGGGCTTTTGATTTCGGAATTTCGGGATGCCGGGCAAGGACGTGGCTTCCCGCAT
CGCAACACCGGCGGTTTGAC

Downstream 100 bases:

>100_bases
AATATTTATGACTTTCGCACCCTTTGTTACGAAACCTAACAGTTGATGATCCAGGCCAAGCTTGAACCGATTAGCGGCCT
ATGCCATAGGCAGGATCAAT

Product: heat shock protein DnaJ domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MRDPYKILGVKRDAAADEIKAAWRNMAKSAHPDHNQGDPTATARFAEIGRAYETLKDPRKRSLFDNAVRMAEAKKNEQTI
MQQRQAAREAAVRAKAAQANAERVMEELARAAQKAAADGSRQQAGSAEPADEMVDRIFGAQARAAAGGQAQARAHQAQYQ
QAQSQQTQNQQAQNQQAQNQQASEAGRRVDGDATEGDTKSDEEAGEAGPNAGANLPLPLSILTSLVRRFTGAKDTGLEKA
PDEVATATVTIDDVLKSGWITASLPEGREIGFALPAGTRDGHELRLKGQGFKLPGMQRGDAVINIRIAPDPRFTVDGFDL
HAVLPLSIENAVLGTEARIEGPSGPLDITIPAWSGSDKTIKIPGQGLPREEGGRGDLVVELRIILWEKPDDKVTDLMRSM
REGLFL

Sequences:

>Translated_406_residues
MRDPYKILGVKRDAAADEIKAAWRNMAKSAHPDHNQGDPTATARFAEIGRAYETLKDPRKRSLFDNAVRMAEAKKNEQTI
MQQRQAAREAAVRAKAAQANAERVMEELARAAQKAAADGSRQQAGSAEPADEMVDRIFGAQARAAAGGQAQARAHQAQYQ
QAQSQQTQNQQAQNQQAQNQQASEAGRRVDGDATEGDTKSDEEAGEAGPNAGANLPLPLSILTSLVRRFTGAKDTGLEKA
PDEVATATVTIDDVLKSGWITASLPEGREIGFALPAGTRDGHELRLKGQGFKLPGMQRGDAVINIRIAPDPRFTVDGFDL
HAVLPLSIENAVLGTEARIEGPSGPLDITIPAWSGSDKTIKIPGQGLPREEGGRGDLVVELRIILWEKPDDKVTDLMRSM
REGLFL
>Mature_406_residues
MRDPYKILGVKRDAAADEIKAAWRNMAKSAHPDHNQGDPTATARFAEIGRAYETLKDPRKRSLFDNAVRMAEAKKNEQTI
MQQRQAAREAAVRAKAAQANAERVMEELARAAQKAAADGSRQQAGSAEPADEMVDRIFGAQARAAAGGQAQARAHQAQYQ
QAQSQQTQNQQAQNQQAQNQQASEAGRRVDGDATEGDTKSDEEAGEAGPNAGANLPLPLSILTSLVRRFTGAKDTGLEKA
PDEVATATVTIDDVLKSGWITASLPEGREIGFALPAGTRDGHELRLKGQGFKLPGMQRGDAVINIRIAPDPRFTVDGFDL
HAVLPLSIENAVLGTEARIEGPSGPLDITIPAWSGSDKTIKIPGQGLPREEGGRGDLVVELRIILWEKPDDKVTDLMRSM
REGLFL

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG2214

COG function: function code O; DnaJ-class molecular chaperone

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI201862518, Length=64, Percent_Identity=51.5625, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI56549115, Length=64, Percent_Identity=51.5625, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI201862587, Length=64, Percent_Identity=51.5625, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI7706495, Length=64, Percent_Identity=50, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1787235, Length=146, Percent_Identity=32.8767123287671, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786197, Length=64, Percent_Identity=48.4375, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI212645553, Length=64, Percent_Identity=50, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115532476, Length=63, Percent_Identity=47.6190476190476, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323870, Length=64, Percent_Identity=43.75, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19920464, Length=342, Percent_Identity=25.7309941520468, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24658562, Length=65, Percent_Identity=53.8461538461538, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24658555, Length=65, Percent_Identity=53.8461538461538, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012724
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- InterPro:   IPR001305 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]

EC number: NA

Molecular weight: Translated: 43759; Mature: 43759

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS00636 DNAJ_1 ; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDPYKILGVKRDAAADEIKAAWRNMAKSAHPDHNQGDPTATARFAEIGRAYETLKDPRK
CCCCHHHEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHH
RSLFDNAVRMAEAKKNEQTIMQQRQAAREAAVRAKAAQANAERVMEELARAAQKAAADGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RQQAGSAEPADEMVDRIFGAQARAAAGGQAQARAHQAQYQQAQSQQTQNQQAQNQQAQNQ
HHCCCCCCCHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QASEAGRRVDGDATEGDTKSDEEAGEAGPNAGANLPLPLSILTSLVRRFTGAKDTGLEKA
HHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
PDEVATATVTIDDVLKSGWITASLPEGREIGFALPAGTRDGHELRLKGQGFKLPGMQRGD
CHHHHEEEEEHHHHHHCCCEEEECCCCCCCEEECCCCCCCCCEEEEECCCCCCCCCCCCC
AVINIRIAPDPRFTVDGFDLHAVLPLSIENAVLGTEARIEGPSGPLDITIPAWSGSDKTI
EEEEEEECCCCCEEECCCCEEEEEEEECCCCEECCCCEECCCCCCEEEEEECCCCCCCEE
KIPGQGLPREEGGRGDLVVELRIILWEKPDDKVTDLMRSMREGLFL
ECCCCCCCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRDPYKILGVKRDAAADEIKAAWRNMAKSAHPDHNQGDPTATARFAEIGRAYETLKDPRK
CCCCHHHEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHH
RSLFDNAVRMAEAKKNEQTIMQQRQAAREAAVRAKAAQANAERVMEELARAAQKAAADGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RQQAGSAEPADEMVDRIFGAQARAAAGGQAQARAHQAQYQQAQSQQTQNQQAQNQQAQNQ
HHCCCCCCCHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QASEAGRRVDGDATEGDTKSDEEAGEAGPNAGANLPLPLSILTSLVRRFTGAKDTGLEKA
HHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
PDEVATATVTIDDVLKSGWITASLPEGREIGFALPAGTRDGHELRLKGQGFKLPGMQRGD
CHHHHEEEEEHHHHHHCCCEEEECCCCCCCEEECCCCCCCCCEEEEECCCCCCCCCCCCC
AVINIRIAPDPRFTVDGFDLHAVLPLSIENAVLGTEARIEGPSGPLDITIPAWSGSDKTI
EEEEEEECCCCCEEECCCCEEEEEEEECCCCEECCCCEECCCCCCEEEEEECCCCCCCEE
KIPGQGLPREEGGRGDLVVELRIILWEKPDDKVTDLMRSMREGLFL
ECCCCCCCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA