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The map label for this gene is moaB [H]

Identifier: 209548126

GI number: 209548126

Start: 534255

End: 534806

Strand: Reverse

Name: moaB [H]

Synonym: Rleg2_0520

Alternate gene names: 209548126

Gene position: 534806-534255 (Counterclockwise)

Preceding gene: 209548127

Following gene: 209548123

Centisome position: 11.79

GC content: 64.49

Gene sequence:

>552_bases
ATGGCAGATCAGGACGACAACCGCCCCTTCATCGCCGTCGGCATTGCGGTTCTCACCGTCTCGGATACGCGCACGCCGGA
AACGGACAAGTCAGGCGACACGCTGGCGGCGCGAATCACCGAGGCGGGCCACCGGCTGGTCGACCGGGCGATCGTGCCCG
ATGATCGCGAGAAAATCGCTGCCCGGGTCAAGGCCTGGACCGAGAGAGAGGAGATCGACGTCGTCATCACCACTGGCGGC
ACCGGCTTTACCGGCCGCGATGTGACGCCCGAGGCGCTGGAGCCTTTGTTCGAAAAACGCATGGACGGCTTTTCCGCCAT
CTTCCACCGCATCTCCTACGAGAAGATCGGCACGGCGACGATCCAGTCGCGCGCCACGGCAGGCGTTGCCAACGCCACCT
TCATCTTCGCGCTGCCGGGGTCGCCCGGCGCCTGCCGGGATGCCTGGGACGGCATTTTGAAAGCACAGCTCGACTACCGC
AGCCTGCCCTGCAATTTCGTCGAGATCATGCCGCGTCTGGACGAGCACCTGAAACGCGGCGCGATGAAATAG

Upstream 100 bases:

>100_bases
TTGCGAGCATGGCTGAGGCGCAAGACGCGGCGGCAGCCCTTCACGGCGAGCGGCCCGACTGGTATTTCCAGGCGACGGAA
ACGGTTTCGGGAGGCATGTG

Downstream 100 bases:

>100_bases
GCTGGCTGACCCGGCTCGCTATGTGGCAAGGCCCGGCAGAGTGGGCATCGTTTCCCAGCTGTCACCCGACAGCAGGATGC
AGCTTGTGCCGTGAACATCC

Product: molybdenum cofactor biosynthesis protein B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MADQDDNRPFIAVGIAVLTVSDTRTPETDKSGDTLAARITEAGHRLVDRAIVPDDREKIAARVKAWTEREEIDVVITTGG
TGFTGRDVTPEALEPLFEKRMDGFSAIFHRISYEKIGTATIQSRATAGVANATFIFALPGSPGACRDAWDGILKAQLDYR
SLPCNFVEIMPRLDEHLKRGAMK

Sequences:

>Translated_183_residues
MADQDDNRPFIAVGIAVLTVSDTRTPETDKSGDTLAARITEAGHRLVDRAIVPDDREKIAARVKAWTEREEIDVVITTGG
TGFTGRDVTPEALEPLFEKRMDGFSAIFHRISYEKIGTATIQSRATAGVANATFIFALPGSPGACRDAWDGILKAQLDYR
SLPCNFVEIMPRLDEHLKRGAMK
>Mature_182_residues
ADQDDNRPFIAVGIAVLTVSDTRTPETDKSGDTLAARITEAGHRLVDRAIVPDDREKIAARVKAWTEREEIDVVITTGGT
GFTGRDVTPEALEPLFEKRMDGFSAIFHRISYEKIGTATIQSRATAGVANATFIFALPGSPGACRDAWDGILKAQLDYRS
LPCNFVEIMPRLDEHLKRGAMK

Specific function: Maybe involved in the biosynthesis of molybdopterin. Can bind GTP and has low GTPase activity. Can bind MPT, but has no MPT adenylyl transferase activity [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=146, Percent_Identity=33.5616438356164, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI10880983, Length=146, Percent_Identity=33.5616438356164, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1787000, Length=157, Percent_Identity=53.5031847133758, Blast_Score=174, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17564954, Length=144, Percent_Identity=36.8055555555556, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17136978, Length=144, Percent_Identity=39.5833333333333, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24638841, Length=144, Percent_Identity=39.5833333333333, Blast_Score=93, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR013484
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 20062; Mature: 19931

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADQDDNRPFIAVGIAVLTVSDTRTPETDKSGDTLAARITEAGHRLVDRAIVPDDREKIA
CCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
ARVKAWTEREEIDVVITTGGTGFTGRDVTPEALEPLFEKRMDGFSAIFHRISYEKIGTAT
HHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHH
IQSRATAGVANATFIFALPGSPGACRDAWDGILKAQLDYRSLPCNFVEIMPRLDEHLKRG
HHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHC
AMK
CCC
>Mature Secondary Structure 
ADQDDNRPFIAVGIAVLTVSDTRTPETDKSGDTLAARITEAGHRLVDRAIVPDDREKIA
CCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
ARVKAWTEREEIDVVITTGGTGFTGRDVTPEALEPLFEKRMDGFSAIFHRISYEKIGTAT
HHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHH
IQSRATAGVANATFIFALPGSPGACRDAWDGILKAQLDYRSLPCNFVEIMPRLDEHLKRG
HHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHC
AMK
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]