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The map label for this gene is aglR [H]

Identifier: 209547962

GI number: 209547962

Start: 356858

End: 357886

Strand: Reverse

Name: aglR [H]

Synonym: Rleg2_0354

Alternate gene names: 209547962

Gene position: 357886-356858 (Counterclockwise)

Preceding gene: 209547969

Following gene: 209547935

Centisome position: 7.89

GC content: 63.75

Gene sequence:

>1029_bases
GTGAATCTCAAACAGCTATCGGAATTGCTGGGGCTGTCGCAGACGACGGTGAGCCGAGCGCTCAATGGTTATCCCGAGGT
CAACGAGGCCACCCGGGAGCGCGTGCTTCAAGCTGTCAAGGAAACCGGGTATCGCCCGAACAAGGCGGCGCAGCGGCTTG
CGACCGGCAAGGCCGGCTCGATCGGCCTTGTCATGCCGACCGCGCCCGGCCATCAGTCCGACGTGCATTTCGGCGAATTC
CTGGCCGGGCTCGGCGAAGAGGCCGTACGCCACGACTTCCACTTCGTCATCATGCCGGCCGACCCGGATGACGAGGTTGC
AGCCCTCAGGCGCCTGGCGATCAGCGGTAATGTCGATGCGCTGTTCGTTGCCTATATGCGCGGCCACGACCCGCGCCTCC
CCATGCTGAAATCGCTCTCGATGCCCTATGTCGTGCACGGGCGATCCTTCGGCTCGGAGCCGGACTATCCCTTTCTCGAC
ATCGACAATGAAGGCGCCTTCTACGATGCGACGCGGCTTCTGCTGCAGCTCGGCCATACGCGCTTTGCGCTGATGAACGG
GCCGATGCATCTCGATTTCGCCATTCGCAGGAAGAACGGTGTCATAGCGGCGCTGGCCGAGCGAGGACTGGCGCTCGACG
AGGATTGCATCAGCCATGCGCTGATGACGGACGAGCAAGGCCTGTTGGCGATGGAACACTTCCTGCAGCTGCCGGAGCGG
CCGACGGCCATCCTCTGCGCCAGCACGGTGCTGGCGCTCGGCGCGATCCGCGCGGTCAACCAGGCTGGATTGCGGCTCGG
CGAGGATATCTCGCTGATCGCCCATGACGACGTGCTGCCGCTGTTGAAGCCGGAAAATTTCTCCGTGCCGCTGACAACGA
CGCGCTCTTCGCTCAGAGCCGCCGGCGTTCGCATCGCACAACGGTTGATCGGCACGGTGAAGCAGGCAGGCCCCTTCCCC
GAACAGGAACTCTGGAAAACCGAACTGATCGTCAGAGCCTCGACCGGCCCTGCCCCGCAGCAGCTCTAA

Upstream 100 bases:

>100_bases
CGCGCCAGATGCTACATAATTGAAAGCGCTTTGGATGCCACTGGGAGGCGGCAGGCCTATTAGAAACGGCCGACGGGCGG
GCCGGGAGGAAGCATAGCAG

Downstream 100 bases:

>100_bases
AGCGCGTGGCGATCTTTCAGATTCGCTCCTTGCTTTAGCTCTTTGTTTTATGCATGTCGTTTGCGGCAAAAGCGCTTCGC
GCTTTGCCTGGGAAAACCGC

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MNLKQLSELLGLSQTTVSRALNGYPEVNEATRERVLQAVKETGYRPNKAAQRLATGKAGSIGLVMPTAPGHQSDVHFGEF
LAGLGEEAVRHDFHFVIMPADPDDEVAALRRLAISGNVDALFVAYMRGHDPRLPMLKSLSMPYVVHGRSFGSEPDYPFLD
IDNEGAFYDATRLLLQLGHTRFALMNGPMHLDFAIRRKNGVIAALAERGLALDEDCISHALMTDEQGLLAMEHFLQLPER
PTAILCASTVLALGAIRAVNQAGLRLGEDISLIAHDDVLPLLKPENFSVPLTTTRSSLRAAGVRIAQRLIGTVKQAGPFP
EQELWKTELIVRASTGPAPQQL

Sequences:

>Translated_342_residues
MNLKQLSELLGLSQTTVSRALNGYPEVNEATRERVLQAVKETGYRPNKAAQRLATGKAGSIGLVMPTAPGHQSDVHFGEF
LAGLGEEAVRHDFHFVIMPADPDDEVAALRRLAISGNVDALFVAYMRGHDPRLPMLKSLSMPYVVHGRSFGSEPDYPFLD
IDNEGAFYDATRLLLQLGHTRFALMNGPMHLDFAIRRKNGVIAALAERGLALDEDCISHALMTDEQGLLAMEHFLQLPER
PTAILCASTVLALGAIRAVNQAGLRLGEDISLIAHDDVLPLLKPENFSVPLTTTRSSLRAAGVRIAQRLIGTVKQAGPFP
EQELWKTELIVRASTGPAPQQL
>Mature_342_residues
MNLKQLSELLGLSQTTVSRALNGYPEVNEATRERVLQAVKETGYRPNKAAQRLATGKAGSIGLVMPTAPGHQSDVHFGEF
LAGLGEEAVRHDFHFVIMPADPDDEVAALRRLAISGNVDALFVAYMRGHDPRLPMLKSLSMPYVVHGRSFGSEPDYPFLD
IDNEGAFYDATRLLLQLGHTRFALMNGPMHLDFAIRRKNGVIAALAERGLALDEDCISHALMTDEQGLLAMEHFLQLPER
PTAILCASTVLALGAIRAVNQAGLRLGEDISLIAHDDVLPLLKPENFSVPLTTTRSSLRAAGVRIAQRLIGTVKQAGPFP
EQELWKTELIVRASTGPAPQQL

Specific function: Probable regulatory protein for the binding-protein- dependent transport system for alpha-glucosides such as sucrose, maltose and trehalose [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=345, Percent_Identity=29.2753623188406, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI1787948, Length=282, Percent_Identity=30.1418439716312, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1789068, Length=342, Percent_Identity=28.0701754385965, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789202, Length=281, Percent_Identity=31.6725978647687, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1790194, Length=282, Percent_Identity=27.6595744680851, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787580, Length=275, Percent_Identity=22.1818181818182, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787906, Length=313, Percent_Identity=26.8370607028754, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788474, Length=300, Percent_Identity=29, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI48994940, Length=336, Percent_Identity=23.5119047619048, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37279; Mature: 37279

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKQLSELLGLSQTTVSRALNGYPEVNEATRERVLQAVKETGYRPNKAAQRLATGKAGS
CCHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCC
IGLVMPTAPGHQSDVHFGEFLAGLGEEAVRHDFHFVIMPADPDDEVAALRRLAISGNVDA
EEEEECCCCCCCCCCCHHHHHHHCCHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCHH
LFVAYMRGHDPRLPMLKSLSMPYVVHGRSFGSEPDYPFLDIDNEGAFYDATRLLLQLGHT
EEEEEHHCCCCCCCHHHHCCCCEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCC
RFALMNGPMHLDFAIRRKNGVIAALAERGLALDEDCISHALMTDEQGLLAMEHFLQLPER
EEEEECCCEEEEEEEEECCCEEEEHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCC
PTAILCASTVLALGAIRAVNQAGLRLGEDISLIAHDDVLPLLKPENFSVPLTTTRSSLRA
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
AGVRIAQRLIGTVKQAGPFPEQELWKTELIVRASTGPAPQQL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHEEEEECCCCCCCCC
>Mature Secondary Structure
MNLKQLSELLGLSQTTVSRALNGYPEVNEATRERVLQAVKETGYRPNKAAQRLATGKAGS
CCHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCC
IGLVMPTAPGHQSDVHFGEFLAGLGEEAVRHDFHFVIMPADPDDEVAALRRLAISGNVDA
EEEEECCCCCCCCCCCHHHHHHHCCHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCHH
LFVAYMRGHDPRLPMLKSLSMPYVVHGRSFGSEPDYPFLDIDNEGAFYDATRLLLQLGHT
EEEEEHHCCCCCCCHHHHCCCCEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCC
RFALMNGPMHLDFAIRRKNGVIAALAERGLALDEDCISHALMTDEQGLLAMEHFLQLPER
EEEEECCCEEEEEEEEECCCEEEEHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCC
PTAILCASTVLALGAIRAVNQAGLRLGEDISLIAHDDVLPLLKPENFSVPLTTTRSSLRA
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
AGVRIAQRLIGTVKQAGPFPEQELWKTELIVRASTGPAPQQL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]