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The map label for this gene is aphA [H]

Identifier: 209547897

GI number: 209547897

Start: 293862

End: 294572

Strand: Reverse

Name: aphA [H]

Synonym: Rleg2_0289

Alternate gene names: 209547897

Gene position: 294572-293862 (Counterclockwise)

Preceding gene: 209547898

Following gene: 209547893

Centisome position: 6.49

GC content: 62.17

Gene sequence:

>711_bases
ATGTCATCAAACCCGACGAGACGACCGGAAGAGGACGATAGCAGCGAGGAGCGCATCAAGCGTTTTCTCGCAACCGCCTC
GCACGATCTGCAATCGCCGTTGCGCCATATCGCCATGTATGCCGAACTGCTGCTCGACGATCTCGAGGGAACACTCGACG
GCGAACAGCTTCAGAGCCTCCGGATGATCATGGAAAAGGCGCAAGCTGCGCAGCGCCTGACCAAGGCATTGATGAGCCTT
GCCGGTGGAGCGCCTCAGGTGACGCCCGAAGAGGTCGATCTGCAGGCGCTGGCCGAAAATGTCTGGGGCGAACTGACCGA
CGAAATCGCGGTTTCCGATGCGACGCTGGAAAGCCAGGGCCTGCCTTCCCTCCGGACCGACCCTGCCCTGCTCGGCCTGG
TGCTGAGGCATCTGCTGACCAATGCGCTGACCTATCGCAGCGAAGCGCCGCTTCATGTGGTCATCAGCGCGGAGCGGGAG
ATGGCGGATTGGTTCATCCGGATTTCCGACAATGGGGCGGGCATCGATCCGGCTTATCGGGAGCGGATCTTCGAGCCGTT
CTGGAAATTGCCGAAGGTGGGAACGGTGCCGGGCGCCGGCCTCGGACTGACGACGGCGCGGGAGTTTCTGGCGGCGCTTG
GCGGCGATCTCAGCCTTGAACATTCGGATCAAAACGGCAGCCGCTTCCTCATCCGCCTTTCGGTCGCCTGA

Upstream 100 bases:

>100_bases
CTGCAAGGATAAAATCCTGCAGCGATTCAAAGGATTACCGCGTCCTTGGCGCGTCTGATAGGATGTAGGGCGCTATAGCA
GAGATCGGGGAAACCGCCAG

Downstream 100 bases:

>100_bases
GCTTCACGAGCGCATCTTTTCAGATGCTGTAATCGTCCTTCCAAAAATCCGGGACGTCATAGTTCACATATTCGCGGATG
ATGTGCTGCAGCGTCTGGGC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSSNPTRRPEEDDSSEERIKRFLATASHDLQSPLRHIAMYAELLLDDLEGTLDGEQLQSLRMIMEKAQAAQRLTKALMSL
AGGAPQVTPEEVDLQALAENVWGELTDEIAVSDATLESQGLPSLRTDPALLGLVLRHLLTNALTYRSEAPLHVVISAERE
MADWFIRISDNGAGIDPAYRERIFEPFWKLPKVGTVPGAGLGLTTAREFLAALGGDLSLEHSDQNGSRFLIRLSVA

Sequences:

>Translated_236_residues
MSSNPTRRPEEDDSSEERIKRFLATASHDLQSPLRHIAMYAELLLDDLEGTLDGEQLQSLRMIMEKAQAAQRLTKALMSL
AGGAPQVTPEEVDLQALAENVWGELTDEIAVSDATLESQGLPSLRTDPALLGLVLRHLLTNALTYRSEAPLHVVISAERE
MADWFIRISDNGAGIDPAYRERIFEPFWKLPKVGTVPGAGLGLTTAREFLAALGGDLSLEHSDQNGSRFLIRLSVA
>Mature_235_residues
SSNPTRRPEEDDSSEERIKRFLATASHDLQSPLRHIAMYAELLLDDLEGTLDGEQLQSLRMIMEKAQAAQRLTKALMSLA
GGAPQVTPEEVDLQALAENVWGELTDEIAVSDATLESQGLPSLRTDPALLGLVLRHLLTNALTYRSEAPLHVVISAEREM
ADWFIRISDNGAGIDPAYRERIFEPFWKLPKVGTVPGAGLGLTTAREFLAALGGDLSLEHSDQNGSRFLIRLSVA

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87081816, Length=235, Percent_Identity=29.3617021276596, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788713, Length=225, Percent_Identity=25.7777777777778, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082128, Length=226, Percent_Identity=27.8761061946903, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786912, Length=226, Percent_Identity=28.3185840707965, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790861, Length=218, Percent_Identity=27.9816513761468, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 25885; Mature: 25753

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSNPTRRPEEDDSSEERIKRFLATASHDLQSPLRHIAMYAELLLDDLEGTLDGEQLQSL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
RMIMEKAQAAQRLTKALMSLAGGAPQVTPEEVDLQALAENVWGELTDEIAVSDATLESQG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCC
LPSLRTDPALLGLVLRHLLTNALTYRSEAPLHVVISAEREMADWFIRISDNGAGIDPAYR
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHEEEEEEECCCCCCCCHHHH
ERIFEPFWKLPKVGTVPGAGLGLTTAREFLAALGGDLSLEHSDQNGSRFLIRLSVA
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEECC
>Mature Secondary Structure 
SSNPTRRPEEDDSSEERIKRFLATASHDLQSPLRHIAMYAELLLDDLEGTLDGEQLQSL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
RMIMEKAQAAQRLTKALMSLAGGAPQVTPEEVDLQALAENVWGELTDEIAVSDATLESQG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCC
LPSLRTDPALLGLVLRHLLTNALTYRSEAPLHVVISAEREMADWFIRISDNGAGIDPAYR
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHEEEEEEECCCCCCCCHHHH
ERIFEPFWKLPKVGTVPGAGLGLTTAREFLAALGGDLSLEHSDQNGSRFLIRLSVA
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]