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The map label for this gene is cph2 [H]

Identifier: 209547860

GI number: 209547860

Start: 255890

End: 257872

Strand: Reverse

Name: cph2 [H]

Synonym: Rleg2_0251

Alternate gene names: 209547860

Gene position: 257872-255890 (Counterclockwise)

Preceding gene: 209547862

Following gene: 209547857

Centisome position: 5.68

GC content: 59.86

Gene sequence:

>1983_bases
ATGAGCGGCACCGGCATGAGCGCGTTGCTGAGGATCGCCTTCAGACCAACGGTGAAGCGGAAAACACGCCATACTCTGGC
GGCGCGGGCGTTGAGGCTTGCGGCACTGCGCATCGCGCTGGTCTGCGCCTGTGCGGGCGGTGTGTCCTATTTCATCAACC
ATTCCGCGCTTGAGCAGTCGGTGCGCTCGCAGCTCTCGTTGTCGACGGAACAGGCTTTGCAGCGCGAATCTCTGCCATTT
CGCGAAGTGAAGGACCTCGAAAAGAATTTCCTTGCCGAATTCGACAGGATCTACGCGATACCGGAAGCCCGGCAGTCATT
GGCGCGGAATTTCGACGATATTTTCTATCGCCATGAGGATGGATCCTACACCCAGCGCCCGGGATTATTTGAAGGCGAGC
CTTTGCCCGATGGACGCAGATTTCCCGGCATGTCGGCGACCTATGCGCCTGACGTGACGCCGGATGCGGACGTGAAGACA
CGGTTTGCGCTGTCGTACCTGCTCTCTTACCAATTCGGTTCCGCCGCCAAGGGCCGCCTCTTCAATTTCTACGGCGTGGT
TCCGGAAAAAGGCTTCCCGATCTATCAGGCTGCCGACATCGCCAAGGTTTTCAAATATGAAGGCCCGGATGCGCTGAAGC
TCGAGACTTTCGAATTTTTTTCCCGCGGCTTCGGCGGGCCTCAAAACGAGACCTTCTTCACCCGCATCTATTGGGATCCC
TCCAACAATGCCTGGATGACGACGATTGCGACGGCCGATGCGCCTGATGCTTCGGGCAAACATCGCATCATGGCTTGCGT
CGACGTGCTGCTCGACGATCTGATGAAACGAACCGCAAATCCGACGCTGCCGGGCGCACGCGCGACGATCTTTGCAGCCG
ATAATCAGGGAACTCTGATCTTCGACGGTAAATACACCGATGCGATCACGGCCAGCGCCGGCGAAGCCTCGATTTCCTCC
CTTGAAATCGCCGACTACCAGCCATTGCTGAAGGCGAGCCAGGCGATCGGAGCGGGTTCAGTATCGCTCATCGAGAGCAC
CAGCGAAATTACCGCCGTCGGCCGGATCCCGGATACGCCCTGGGTGCTTGCCGTCCACTATCCGAAATCCCTGATGCGAC
CCGCCATCCTCACCAATCTCGGGATCGTCGTCGCGGTCGGGCTGCTCACCTTGTTCGTCGAACTCTTCATCCTCCGCTCG
ATCCTGCAAAAGCAGGTCGCCGAACCGCTGGTGAGATTGATCCACGCCACGCAGCTGGTCGGTCGTTCCGGCGTTACTGT
TGCCAATGACGCCCTGCCCACGCATTCCGACGACGAGATCGGCGAGCTTGCCCGCGATTTTGCGTCGATGGCCGCGCGCG
TTCACACAGCCCATGAAGCGCTTGAGGGAAAGATACGGGATCGAACGTCCGAGCTGGAGCGGCTCAATCAGAAGCTCCTG
ACGATCAGCCAGACGGACGAGATGACGGGCGTCGCCAACCGGCGCCGCTTCGACGAGGTTCTCGCAAGCGAGCTCGCCGG
GCTTGGACAAGGGCAGGACCTGTTGATGCTTGCCATGGTGGATGCCGATTGGTTCAAAGGCTATAACGACCGATACGGCC
ATCCGGCGGGAGACGCCTGTCTCAAGGAAATCGCCAGGGTGCTGGAACGCAATACACGCAGCAAACAGGACGTTGTTGCC
CGCTATGGCGGAGAGGAATTCGCCATCATTGCGCGGATCGCCTCAGCCAGCAACGCGCCCGTCATCGGACAGGCCCTATG
TTCGGCAATGGCGACCGTCAAGCTGGCGCATGAGGGATCGCCTTTCGGGCACGTGACGCTCAGCGTCGGCATCGCTCTGG
CGGCCCCGGATCAGAATATCTCTCCGGAAGCGCTCTTGCTCGAAGCCGATCGCGCGCTCTATCGCGCCAAGCAGGCAGGG
CGAAATCAAGCCGTCGTTGCCGAGCCTTCTGCTGACATGCAGATCCAGCAGATAGGCGCTTAA

Upstream 100 bases:

>100_bases
ACGACTGAGGTAAATGCATGATCTCGAACAGCCTGCCGGTTATTGGCATGCGATCGGTCGACGCAATCGGGTTGTCGATC
ATGCAGGCCGGATCGTCGAA

Downstream 100 bases:

>100_bases
AAATTCTAAAGCCCGGGCTCGGCAATGCCCGTTTTGCAGAGGCACGGCTGTATCCGACGCCCCGAACAGTTCGAGTAAGG
GAGCATTCTTCGGCGCCCAT

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 660; Mature: 659

Protein sequence:

>660_residues
MSGTGMSALLRIAFRPTVKRKTRHTLAARALRLAALRIALVCACAGGVSYFINHSALEQSVRSQLSLSTEQALQRESLPF
REVKDLEKNFLAEFDRIYAIPEARQSLARNFDDIFYRHEDGSYTQRPGLFEGEPLPDGRRFPGMSATYAPDVTPDADVKT
RFALSYLLSYQFGSAAKGRLFNFYGVVPEKGFPIYQAADIAKVFKYEGPDALKLETFEFFSRGFGGPQNETFFTRIYWDP
SNNAWMTTIATADAPDASGKHRIMACVDVLLDDLMKRTANPTLPGARATIFAADNQGTLIFDGKYTDAITASAGEASISS
LEIADYQPLLKASQAIGAGSVSLIESTSEITAVGRIPDTPWVLAVHYPKSLMRPAILTNLGIVVAVGLLTLFVELFILRS
ILQKQVAEPLVRLIHATQLVGRSGVTVANDALPTHSDDEIGELARDFASMAARVHTAHEALEGKIRDRTSELERLNQKLL
TISQTDEMTGVANRRRFDEVLASELAGLGQGQDLLMLAMVDADWFKGYNDRYGHPAGDACLKEIARVLERNTRSKQDVVA
RYGGEEFAIIARIASASNAPVIGQALCSAMATVKLAHEGSPFGHVTLSVGIALAAPDQNISPEALLLEADRALYRAKQAG
RNQAVVAEPSADMQIQQIGA

Sequences:

>Translated_660_residues
MSGTGMSALLRIAFRPTVKRKTRHTLAARALRLAALRIALVCACAGGVSYFINHSALEQSVRSQLSLSTEQALQRESLPF
REVKDLEKNFLAEFDRIYAIPEARQSLARNFDDIFYRHEDGSYTQRPGLFEGEPLPDGRRFPGMSATYAPDVTPDADVKT
RFALSYLLSYQFGSAAKGRLFNFYGVVPEKGFPIYQAADIAKVFKYEGPDALKLETFEFFSRGFGGPQNETFFTRIYWDP
SNNAWMTTIATADAPDASGKHRIMACVDVLLDDLMKRTANPTLPGARATIFAADNQGTLIFDGKYTDAITASAGEASISS
LEIADYQPLLKASQAIGAGSVSLIESTSEITAVGRIPDTPWVLAVHYPKSLMRPAILTNLGIVVAVGLLTLFVELFILRS
ILQKQVAEPLVRLIHATQLVGRSGVTVANDALPTHSDDEIGELARDFASMAARVHTAHEALEGKIRDRTSELERLNQKLL
TISQTDEMTGVANRRRFDEVLASELAGLGQGQDLLMLAMVDADWFKGYNDRYGHPAGDACLKEIARVLERNTRSKQDVVA
RYGGEEFAIIARIASASNAPVIGQALCSAMATVKLAHEGSPFGHVTLSVGIALAAPDQNISPEALLLEADRALYRAKQAG
RNQAVVAEPSADMQIQQIGA
>Mature_659_residues
SGTGMSALLRIAFRPTVKRKTRHTLAARALRLAALRIALVCACAGGVSYFINHSALEQSVRSQLSLSTEQALQRESLPFR
EVKDLEKNFLAEFDRIYAIPEARQSLARNFDDIFYRHEDGSYTQRPGLFEGEPLPDGRRFPGMSATYAPDVTPDADVKTR
FALSYLLSYQFGSAAKGRLFNFYGVVPEKGFPIYQAADIAKVFKYEGPDALKLETFEFFSRGFGGPQNETFFTRIYWDPS
NNAWMTTIATADAPDASGKHRIMACVDVLLDDLMKRTANPTLPGARATIFAADNQGTLIFDGKYTDAITASAGEASISSL
EIADYQPLLKASQAIGAGSVSLIESTSEITAVGRIPDTPWVLAVHYPKSLMRPAILTNLGIVVAVGLLTLFVELFILRSI
LQKQVAEPLVRLIHATQLVGRSGVTVANDALPTHSDDEIGELARDFASMAARVHTAHEALEGKIRDRTSELERLNQKLLT
ISQTDEMTGVANRRRFDEVLASELAGLGQGQDLLMLAMVDADWFKGYNDRYGHPAGDACLKEIARVLERNTRSKQDVVAR
YGGEEFAIIARIASASNAPVIGQALCSAMATVKLAHEGSPFGHVTLSVGIALAAPDQNISPEALLLEADRALYRAKQAGR
NQAVVAEPSADMQIQQIGA

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI87081881, Length=179, Percent_Identity=35.7541899441341, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1786584, Length=178, Percent_Identity=34.2696629213483, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1787816, Length=170, Percent_Identity=36.4705882352941, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788381, Length=185, Percent_Identity=34.0540540540541, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI145693134, Length=167, Percent_Identity=32.9341317365269, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787262, Length=168, Percent_Identity=29.7619047619048, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87082007, Length=185, Percent_Identity=33.5135135135135, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787541, Length=192, Percent_Identity=29.6875, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787802, Length=170, Percent_Identity=34.7058823529412, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1787056, Length=161, Percent_Identity=30.4347826086957, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081977, Length=189, Percent_Identity=29.6296296296296, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1788956, Length=214, Percent_Identity=31.3084112149533, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 71907; Mature: 71775

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS50885 HAMP ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGTGMSALLRIAFRPTVKRKTRHTLAARALRLAALRIALVCACAGGVSYFINHSALEQS
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VRSQLSLSTEQALQRESLPFREVKDLEKNFLAEFDRIYAIPEARQSLARNFDDIFYRHED
HHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHEEECCC
GSYTQRPGLFEGEPLPDGRRFPGMSATYAPDVTPDADVKTRFALSYLLSYQFGSAAKGRL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCE
FNFYGVVPEKGFPIYQAADIAKVFKYEGPDALKLETFEFFSRGFGGPQNETFFTRIYWDP
EEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHCCCCCCCCCEEEEEEEECC
SNNAWMTTIATADAPDASGKHRIMACVDVLLDDLMKRTANPTLPGARATIFAADNQGTLI
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEE
FDGKYTDAITASAGEASISSLEIADYQPLLKASQAIGAGSVSLIESTSEITAVGRIPDTP
ECCCCCCCEECCCCCCCCCEEEECCCHHHHHHHHHCCCCCHHHHHCCHHHEEECCCCCCC
WVLAVHYPKSLMRPAILTNLGIVVAVGLLTLFVELFILRSILQKQVAEPLVRLIHATQLV
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRSGVTVANDALPTHSDDEIGELARDFASMAARVHTAHEALEGKIRDRTSELERLNQKLL
CCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
TISQTDEMTGVANRRRFDEVLASELAGLGQGQDLLMLAMVDADWFKGYNDRYGHPAGDAC
EEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECHHHHCCCCCCCCCCCHHHH
LKEIARVLERNTRSKQDVVARYGGEEFAIIARIASASNAPVIGQALCSAMATVKLAHEGS
HHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEEHHCCCCCCHHHHHHHHHHHHHHEECCCC
PFGHVTLSVGIALAAPDQNISPEALLLEADRALYRAKQAGRNQAVVAEPSADMQIQQIGA
CCEEEEEEEEEEEECCCCCCCCCCEEEHHHHHHHHHHHCCCCCEEEECCCCCCCHHCCCC
>Mature Secondary Structure 
SGTGMSALLRIAFRPTVKRKTRHTLAARALRLAALRIALVCACAGGVSYFINHSALEQS
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VRSQLSLSTEQALQRESLPFREVKDLEKNFLAEFDRIYAIPEARQSLARNFDDIFYRHED
HHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHEEECCC
GSYTQRPGLFEGEPLPDGRRFPGMSATYAPDVTPDADVKTRFALSYLLSYQFGSAAKGRL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCE
FNFYGVVPEKGFPIYQAADIAKVFKYEGPDALKLETFEFFSRGFGGPQNETFFTRIYWDP
EEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHCCCCCCCCCEEEEEEEECC
SNNAWMTTIATADAPDASGKHRIMACVDVLLDDLMKRTANPTLPGARATIFAADNQGTLI
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEE
FDGKYTDAITASAGEASISSLEIADYQPLLKASQAIGAGSVSLIESTSEITAVGRIPDTP
ECCCCCCCEECCCCCCCCCEEEECCCHHHHHHHHHCCCCCHHHHHCCHHHEEECCCCCCC
WVLAVHYPKSLMRPAILTNLGIVVAVGLLTLFVELFILRSILQKQVAEPLVRLIHATQLV
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRSGVTVANDALPTHSDDEIGELARDFASMAARVHTAHEALEGKIRDRTSELERLNQKLL
CCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
TISQTDEMTGVANRRRFDEVLASELAGLGQGQDLLMLAMVDADWFKGYNDRYGHPAGDAC
EEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECHHHHCCCCCCCCCCCHHHH
LKEIARVLERNTRSKQDVVARYGGEEFAIIARIASASNAPVIGQALCSAMATVKLAHEGS
HHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEEHHCCCCCCHHHHHHHHHHHHHHEECCCC
PFGHVTLSVGIALAAPDQNISPEALLLEADRALYRAKQAGRNQAVVAEPSADMQIQQIGA
CCEEEEEEEEEEEECCCCCCCCCCEEEHHHHHHHHHHHCCCCCEEEECCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]