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The map label for this gene is fadB1 [H]

Identifier: 209547838

GI number: 209547838

Start: 236780

End: 237832

Strand: Direct

Name: fadB1 [H]

Synonym: Rleg2_0229

Alternate gene names: 209547838

Gene position: 236780-237832 (Clockwise)

Preceding gene: 209547837

Following gene: 209547841

Centisome position: 5.22

GC content: 68.09

Gene sequence:

>1053_bases
ATGCAGGACGGCGAAGTCATCATCGAACAGCGGGGCACAGCCGGCATCATCCGGCTCAACCGGCCGCGGGCGCTGAACAG
CCTGACGCTGCCGATGATCCGGGCGATCACCGAGGCCCTTGATGGCTTTGCCGCAGATGCCGCGGTGGCGAGCGTCGTGG
TGGCGGGGGAGGGCGAACGCGGCTTCTGCGCCGGCGGCGACATCCGCGCCCTGCATGAAAGCGCCCACGCCGGCGATGGC
CTCGCAAGCGCCTTCTGGCGCGAGGAATTCCGCCTCAACCATCAGATCGCCGTCTACCCCAAACCCTATGTCGCGCTGAT
GGACGGCATCACCATGGGCGGCGGTGTCGGTCTGTCCTCGCACGGCCGCCACCGCATCGTCACCGAGCGCACCCGGCTTG
CCATGCCCGAAACCGGCATCGGCTACGTCCCCGATGTCGGCGCCACCTGGCTGCTGCCGAAGGCCCCGGGCGAAGCCGGA
ACATGGCTCGGCCTGACCGGGCTCGATATTGGTGCGGCCGACGCCATCCATGCCGGGCTTGCCGACCGCCAGATCGCTGC
CGCGCGGCTCGGCTCGGTGATCGAGGCGCTGTCGGCCTTGCCGCGCGGCAGCGCGTCCAGCGATGTCGATGCCCTCTTGC
AGGGGCTTGCTGAGCCTGCGGGAGAAAGCCGGCTCAAGCAGAATGCCGCGATGATCGATCGCGCCTTTCGTTTCGACAGT
GTCGAGGAAATCCTGGCAGCGCTTGCCGGGGAAGAGGGCGACTTCGCCGCCGAGACCCGCCGGGTGCTGTCGACCCGTTC
GCCGACCAGCCTGAAGCTCGCTTTGGCGCTGCTCAGAGCCGGCCGCCGCAGCGCCTCGCTTGCCGAATGCCTCGGCCGCG
AACTCGGCGCCTGCCTGCAGATGCTCGATAACCCCGATTTCTTCGAAGGCATCCGCGCCGCCGTCATCGACAAGGACCGC
AATCCGAAATGGTCGCCGGCAAGTGTCGAGGCTGTGGAACCGGCAATGGTCGAGCGCTTCCTGAAACCGGCCGAGCCGCC
GCTATCACTCTGA

Upstream 100 bases:

>100_bases
ACTGGAGCGACGCTGCATCGTCGTCTATTCATGGTTACGAGCCTTTCCTGGGCAGAATGCTTCAATCGGATCAGGAAGGC
TCCAGCAGCGGAGGTAAACC

Downstream 100 bases:

>100_bases
CTTCGTTTGCTTATCGCCACATGCCGCGCATGCGGGCGCCGACATCGATGCGCACCTGCCGCGCCTGCGCTTGCGCGGCC
GCCTCGGATTTCACCTGCGG

Product: 3-hydroxyisobutyryl-CoA hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MQDGEVIIEQRGTAGIIRLNRPRALNSLTLPMIRAITEALDGFAADAAVASVVVAGEGERGFCAGGDIRALHESAHAGDG
LASAFWREEFRLNHQIAVYPKPYVALMDGITMGGGVGLSSHGRHRIVTERTRLAMPETGIGYVPDVGATWLLPKAPGEAG
TWLGLTGLDIGAADAIHAGLADRQIAAARLGSVIEALSALPRGSASSDVDALLQGLAEPAGESRLKQNAAMIDRAFRFDS
VEEILAALAGEEGDFAAETRRVLSTRSPTSLKLALALLRAGRRSASLAECLGRELGACLQMLDNPDFFEGIRAAVIDKDR
NPKWSPASVEAVEPAMVERFLKPAEPPLSL

Sequences:

>Translated_350_residues
MQDGEVIIEQRGTAGIIRLNRPRALNSLTLPMIRAITEALDGFAADAAVASVVVAGEGERGFCAGGDIRALHESAHAGDG
LASAFWREEFRLNHQIAVYPKPYVALMDGITMGGGVGLSSHGRHRIVTERTRLAMPETGIGYVPDVGATWLLPKAPGEAG
TWLGLTGLDIGAADAIHAGLADRQIAAARLGSVIEALSALPRGSASSDVDALLQGLAEPAGESRLKQNAAMIDRAFRFDS
VEEILAALAGEEGDFAAETRRVLSTRSPTSLKLALALLRAGRRSASLAECLGRELGACLQMLDNPDFFEGIRAAVIDKDR
NPKWSPASVEAVEPAMVERFLKPAEPPLSL
>Mature_350_residues
MQDGEVIIEQRGTAGIIRLNRPRALNSLTLPMIRAITEALDGFAADAAVASVVVAGEGERGFCAGGDIRALHESAHAGDG
LASAFWREEFRLNHQIAVYPKPYVALMDGITMGGGVGLSSHGRHRIVTERTRLAMPETGIGYVPDVGATWLLPKAPGEAG
TWLGLTGLDIGAADAIHAGLADRQIAAARLGSVIEALSALPRGSASSDVDALLQGLAEPAGESRLKQNAAMIDRAFRFDS
VEEILAALAGEEGDFAAETRRVLSTRSPTSLKLALALLRAGRRSASLAECLGRELGACLQMLDNPDFFEGIRAAVIDKDR
NPKWSPASVEAVEPAMVERFLKPAEPPLSL

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=333, Percent_Identity=40.2402402402402, Blast_Score=252, Evalue=4e-67,
Organism=Homo sapiens, GI37594469, Length=303, Percent_Identity=39.6039603960396, Blast_Score=219, Evalue=4e-57,
Organism=Homo sapiens, GI194097323, Length=208, Percent_Identity=33.6538461538462, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI68989263, Length=171, Percent_Identity=30.9941520467836, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1787659, Length=177, Percent_Identity=27.1186440677966, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI221142681, Length=184, Percent_Identity=28.2608695652174, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25144160, Length=346, Percent_Identity=38.4393063583815, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI25144157, Length=346, Percent_Identity=38.4393063583815, Blast_Score=245, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI17554946, Length=177, Percent_Identity=28.8135593220339, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17558304, Length=183, Percent_Identity=31.6939890710383, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17508951, Length=184, Percent_Identity=29.8913043478261, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25144276, Length=184, Percent_Identity=29.8913043478261, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508953, Length=184, Percent_Identity=29.8913043478261, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17540714, Length=195, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=353, Percent_Identity=32.8611898016997, Blast_Score=174, Evalue=2e-44,
Organism=Drosophila melanogaster, GI28571729, Length=338, Percent_Identity=39.0532544378698, Blast_Score=244, Evalue=6e-65,
Organism=Drosophila melanogaster, GI28571730, Length=338, Percent_Identity=39.0532544378698, Blast_Score=244, Evalue=6e-65,
Organism=Drosophila melanogaster, GI20129971, Length=229, Percent_Identity=27.9475982532751, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24653477, Length=229, Percent_Identity=27.9475982532751, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 36944; Mature: 36944

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDGEVIIEQRGTAGIIRLNRPRALNSLTLPMIRAITEALDGFAADAAVASVVVAGEGER
CCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCC
GFCAGGDIRALHESAHAGDGLASAFWREEFRLNHQIAVYPKPYVALMDGITMGGGVGLSS
CCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECCCCHHHHHCCCCCCCCCCCCC
HGRHRIVTERTRLAMPETGIGYVPDVGATWLLPKAPGEAGTWLGLTGLDIGAADAIHAGL
CCCCEEEEHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEECCCCCCCHHHHHHCC
ADRQIAAARLGSVIEALSALPRGSASSDVDALLQGLAEPAGESRLKQNAAMIDRAFRFDS
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC
VEEILAALAGEEGDFAAETRRVLSTRSPTSLKLALALLRAGRRSASLAECLGRELGACLQ
HHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
MLDNPDFFEGIRAAVIDKDRNPKWSPASVEAVEPAMVERFLKPAEPPLSL
HHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MQDGEVIIEQRGTAGIIRLNRPRALNSLTLPMIRAITEALDGFAADAAVASVVVAGEGER
CCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCC
GFCAGGDIRALHESAHAGDGLASAFWREEFRLNHQIAVYPKPYVALMDGITMGGGVGLSS
CCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECCCCHHHHHCCCCCCCCCCCCC
HGRHRIVTERTRLAMPETGIGYVPDVGATWLLPKAPGEAGTWLGLTGLDIGAADAIHAGL
CCCCEEEEHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEECCCCCCCHHHHHHCC
ADRQIAAARLGSVIEALSALPRGSASSDVDALLQGLAEPAGESRLKQNAAMIDRAFRFDS
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC
VEEILAALAGEEGDFAAETRRVLSTRSPTSLKLALALLRAGRRSASLAECLGRELGACLQ
HHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
MLDNPDFFEGIRAAVIDKDRNPKWSPASVEAVEPAMVERFLKPAEPPLSL
HHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751302; 11481430 [H]