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The map label for this gene is aspC [H]

Identifier: 209547835

GI number: 209547835

Start: 232195

End: 233361

Strand: Direct

Name: aspC [H]

Synonym: Rleg2_0226

Alternate gene names: 209547835

Gene position: 232195-233361 (Clockwise)

Preceding gene: 209547834

Following gene: 209547836

Centisome position: 5.12

GC content: 63.67

Gene sequence:

>1167_bases
ATGTCGATCGTGAAGAGCCTCAGCCCGCGCGCCATGGCGGCGCCAGAAAGCGGGATCGTCGAAGTCGTCAATTATGCCCG
CGGCCGCGAAGGCCTGTTGCCGCTCTGGGTGGGTGAAGGCGACCTGCCGACGCCCGATTTCATTAGCAGGGCGGCGATGG
ACGCGCTTGCTTCAGGCGAGACCTTCTACACCTGGCAGCGCGGCATTCCGGAGCTTCGCCAGGCGCTTTCGGATTATTAC
AGCAGACATTTCGGAATCCGGCTTCCGGTCGAGCATTTCTATGTCACCGGTTCCGGCATGCAGGCGATCCAGATCGCCGT
GCAGACGCTGACCTCGCCGGATGATGAACTGGTTTACCTCACCCCCGCCTGGCCGAATATCGCCGCCGCCCTCGAAATCG
CCGGCGCGCGCTCCGTCGGCGTCGAGCTGCAGTTCGAAGGCGGGAAATGGGCGGTCGATCTCGACCGCGTCGAAGCCGCC
ATCACGCCGAAAACCAGGGGCATCTTTATCAACACGCCGTCGAACCCGACGGGCTGGACGGCGACGAAGAAGGATCTTGC
CGACATCCTGGCGCTGGCCCGCCGGCACGATCTCTGGATCATGGCCGATGAAATCTACGCGCTGTATTATTTTGCCGGCG
GCCGGGCGCCGTCTTTCCTCGATGTGATGGAGCCGGCCGACAAGATCATTTTCGTCAACTCCTTCTCGAAGAACTGGTCG
ATGACCGGCTGGCGCGTCGGCTGGATCGTCGCGCCGCCCGAGATGGGTCAGGTGCTCGAAAACCTCATCCAGTATTCGAC
CTCGGGCGTGGCGCAGTTCATGCAGAAGGGCGCCGTTGCAGCCCTTGATCAGGGCGACGATTTCGTTGCCGCCAATATCG
CCAAGGCGGCCCGGTCCCGCGATATTCTCTGCGATGCGCTTGTCGCCACCAACCGCGTCGAGACGCTGAAGCCGGATGGC
GCACTCTATGCCTTCCTGAAGATCGACGGCGTCACCGACAGCCGCAGCGCCGCCATCGACATCGTCGACAAGACAGGCGT
CGGCCTTGCCCCCGGAACCGCCTTCGGCGCCGGCGGCGAACTCTTCCTGCGCGCCTGTTTCCTGCGCGATCCCGACCAGG
TGGCGGTCGCGGCCGAACGTCTCTGCGACTATATCCTCAGGCGCTGA

Upstream 100 bases:

>100_bases
ACCCGCCCGCCCATTCATCACGAAAATCGATATGGCATCACTGGATATCATGGGATTTGCCGGCGCAAATCCACTATGAA
TGCGGAAACCGGAGATATGC

Downstream 100 bases:

>100_bases
GAAGCGGCTCGGTCGGGTGATTTCGTGCCGGAATCGCCCGATCGATAAAACTTGAGCAAAGCCCGAAATCGGCCTCTAAC
CACAAGTCCAAACATACCGG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MSIVKSLSPRAMAAPESGIVEVVNYARGREGLLPLWVGEGDLPTPDFISRAAMDALASGETFYTWQRGIPELRQALSDYY
SRHFGIRLPVEHFYVTGSGMQAIQIAVQTLTSPDDELVYLTPAWPNIAAALEIAGARSVGVELQFEGGKWAVDLDRVEAA
ITPKTRGIFINTPSNPTGWTATKKDLADILALARRHDLWIMADEIYALYYFAGGRAPSFLDVMEPADKIIFVNSFSKNWS
MTGWRVGWIVAPPEMGQVLENLIQYSTSGVAQFMQKGAVAALDQGDDFVAANIAKAARSRDILCDALVATNRVETLKPDG
ALYAFLKIDGVTDSRSAAIDIVDKTGVGLAPGTAFGAGGELFLRACFLRDPDQVAVAAERLCDYILRR

Sequences:

>Translated_388_residues
MSIVKSLSPRAMAAPESGIVEVVNYARGREGLLPLWVGEGDLPTPDFISRAAMDALASGETFYTWQRGIPELRQALSDYY
SRHFGIRLPVEHFYVTGSGMQAIQIAVQTLTSPDDELVYLTPAWPNIAAALEIAGARSVGVELQFEGGKWAVDLDRVEAA
ITPKTRGIFINTPSNPTGWTATKKDLADILALARRHDLWIMADEIYALYYFAGGRAPSFLDVMEPADKIIFVNSFSKNWS
MTGWRVGWIVAPPEMGQVLENLIQYSTSGVAQFMQKGAVAALDQGDDFVAANIAKAARSRDILCDALVATNRVETLKPDG
ALYAFLKIDGVTDSRSAAIDIVDKTGVGLAPGTAFGAGGELFLRACFLRDPDQVAVAAERLCDYILRR
>Mature_387_residues
SIVKSLSPRAMAAPESGIVEVVNYARGREGLLPLWVGEGDLPTPDFISRAAMDALASGETFYTWQRGIPELRQALSDYYS
RHFGIRLPVEHFYVTGSGMQAIQIAVQTLTSPDDELVYLTPAWPNIAAALEIAGARSVGVELQFEGGKWAVDLDRVEAAI
TPKTRGIFINTPSNPTGWTATKKDLADILALARRHDLWIMADEIYALYYFAGGRAPSFLDVMEPADKIIFVNSFSKNWSM
TGWRVGWIVAPPEMGQVLENLIQYSTSGVAQFMQKGAVAALDQGDDFVAANIAKAARSRDILCDALVATNRVETLKPDGA
LYAFLKIDGVTDSRSAAIDIVDKTGVGLAPGTAFGAGGELFLRACFLRDPDQVAVAAERLCDYILRR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=403, Percent_Identity=23.0769230769231, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI169881279, Length=403, Percent_Identity=23.0769230769231, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI4507369, Length=302, Percent_Identity=27.1523178807947, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI56713254, Length=262, Percent_Identity=24.4274809160305, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI56713256, Length=262, Percent_Identity=24.4274809160305, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI7705897, Length=406, Percent_Identity=25.1231527093596, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI33469970, Length=406, Percent_Identity=25.1231527093596, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI169881281, Length=287, Percent_Identity=21.9512195121951, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1788722, Length=360, Percent_Identity=28.6111111111111, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788627, Length=306, Percent_Identity=29.4117647058824, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786816, Length=349, Percent_Identity=24.9283667621776, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787710, Length=186, Percent_Identity=26.8817204301075, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17567369, Length=386, Percent_Identity=23.5751295336788, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17567663, Length=360, Percent_Identity=24.7222222222222, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71994472, Length=240, Percent_Identity=25.8333333333333, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71994476, Length=240, Percent_Identity=25.8333333333333, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI71981209, Length=365, Percent_Identity=22.7397260273973, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322401, Length=239, Percent_Identity=28.8702928870293, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320317, Length=389, Percent_Identity=21.8508997429306, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI28573069, Length=388, Percent_Identity=25, Blast_Score=104, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24646114, Length=388, Percent_Identity=25, Blast_Score=104, Evalue=8e-23,
Organism=Drosophila melanogaster, GI28573067, Length=388, Percent_Identity=25, Blast_Score=104, Evalue=8e-23,
Organism=Drosophila melanogaster, GI28573065, Length=388, Percent_Identity=25, Blast_Score=104, Evalue=8e-23,
Organism=Drosophila melanogaster, GI18859735, Length=352, Percent_Identity=22.1590909090909, Blast_Score=82, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42201; Mature: 42069

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIVKSLSPRAMAAPESGIVEVVNYARGREGLLPLWVGEGDLPTPDFISRAAMDALASGE
CCCHHCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCC
TFYTWQRGIPELRQALSDYYSRHFGIRLPVEHFYVTGSGMQAIQIAVQTLTSPDDELVYL
EEEEHHCCCHHHHHHHHHHHHHHCCEEECHHEEEEECCCHHHHHHHHHHHCCCCCCEEEE
TPAWPNIAAALEIAGARSVGVELQFEGGKWAVDLDRVEAAITPKTRGIFINTPSNPTGWT
ECCCCCHHHHHEECCCCEECEEEEECCCCEEEEHHHHHEEECCCCCEEEEECCCCCCCCC
ATKKDLADILALARRHDLWIMADEIYALYYFAGGRAPSFLDVMEPADKIIFVNSFSKNWS
CCHHHHHHHHHHHHHCCEEEEEHHEEEEEEEECCCCCCHHHHHCCCCEEEEEEECCCCCC
MTGWRVGWIVAPPEMGQVLENLIQYSTSGVAQFMQKGAVAALDQGDDFVAANIAKAARSR
CCCEEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCC
DILCDALVATNRVETLKPDGALYAFLKIDGVTDSRSAAIDIVDKTGVGLAPGTAFGAGGE
CHHHHHHHHCCCCCEECCCCCEEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCHH
LFLRACFLRDPDQVAVAAERLCDYILRR
HHHHHHHCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SIVKSLSPRAMAAPESGIVEVVNYARGREGLLPLWVGEGDLPTPDFISRAAMDALASGE
CCHHCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCC
TFYTWQRGIPELRQALSDYYSRHFGIRLPVEHFYVTGSGMQAIQIAVQTLTSPDDELVYL
EEEEHHCCCHHHHHHHHHHHHHHCCEEECHHEEEEECCCHHHHHHHHHHHCCCCCCEEEE
TPAWPNIAAALEIAGARSVGVELQFEGGKWAVDLDRVEAAITPKTRGIFINTPSNPTGWT
ECCCCCHHHHHEECCCCEECEEEEECCCCEEEEHHHHHEEECCCCCEEEEECCCCCCCCC
ATKKDLADILALARRHDLWIMADEIYALYYFAGGRAPSFLDVMEPADKIIFVNSFSKNWS
CCHHHHHHHHHHHHHCCEEEEEHHEEEEEEEECCCCCCHHHHHCCCCEEEEEEECCCCCC
MTGWRVGWIVAPPEMGQVLENLIQYSTSGVAQFMQKGAVAALDQGDDFVAANIAKAARSR
CCCEEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCC
DILCDALVATNRVETLKPDGALYAFLKIDGVTDSRSAAIDIVDKTGVGLAPGTAFGAGGE
CHHHHHHHHCCCCCEECCCCCEEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCHH
LFLRACFLRDPDQVAVAAERLCDYILRR
HHHHHHHCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]