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The map label for this gene is exoB [H]

Identifier: 209547836

GI number: 209547836

Start: 233555

End: 234589

Strand: Direct

Name: exoB [H]

Synonym: Rleg2_0227

Alternate gene names: 209547836

Gene position: 233555-234589 (Clockwise)

Preceding gene: 209547835

Following gene: 209547837

Centisome position: 5.15

GC content: 63.0

Gene sequence:

>1035_bases
ATGGCGGTTTTGGTGACGGGCGGCGCCGGATATATCGGCAGTCACATGGTTTGGGCGCTGCTCGATGCGGGTGAGGATGT
GGTCGTGCTCGACCGTCTCTCCACGGGCTTTCGCTGGGCCGTGGCGCCGGCGGCGCGTTTCTATCTCGGCGACGTCGCCG
ATCCCGACGTCTTGAAGAAGATCTTCATCGAAAACGACATCGAGGCGATCATTCATTTCGCCGGCTCCGCCGTCGTGCCG
GTCTCGGTCGCCGATCCGCTCTCCTATTACGACAACAATTCAGGCAAGACCCGGGCGCTGCTCTCCGCGTCGGTCGAAGC
CGGCATCCGCAACTTCGTCTTCTCGTCGACCGCGGCCGTCTACGGTCAGCAAAAGACCGACCTGCCGGTGAAGGAGACCG
CCTCCCTCAATCCGGAAAATCCCTACGGCCAGTCGAAGCTGATGACCGAATTCATGCTGCGCGATGCCGCTAGCGCCTAT
GATTTCAACTATGTCGCGCTTCGCTACTTCAACGTCGCCGGCGCCGATCCCGACCACCGCGCCGGCCAGTCGACCTCAGG
CGCCACCCACCTCATCAAGGTTGCCTGCGAGGCAGCACTCGGCAGGCGCGACAGCGTCAGCGTTTATGGCATCGATTATC
CCACCCATGACGGCACCGGCGTGCGCGACTACATCCATGTCACCGATCTTGTCGATGCGCATCTGAAGGCGCTGCAGCAC
CTGCGCCGGGGCAAGGGCTCGCTCGTTGCCAATTGCGGTTATGGCAGCGGCTATTCCGTGCTCGACGTGCTGAACATGGT
CACCCGCCTGCACGGGCATTCCTTCAAGATCCACATGGCGCCGCGCCGCGCCGGCGATTCGGCCAGCGTCGTCGCCGACG
CATCGCTTGCCCGGCAGGTGCTCGACTGGAAGCCCAGACACGATTCGCTCGAAACCATCGTCCAGAGCTCGCTCGATTGG
GAACTCTTCCTGTCGAACAGAAACGTCGACGACCTGCACAGCATCCACCGGGCGCTGGCAGCCGCGTCGTTCTAG

Upstream 100 bases:

>100_bases
ATACCGGTTCAAAGGGCCTGGAACGGCCATTCGATAAGAAAATTGGAAAGAAAAACCGGGCCTGATGCCCCTGCTATAAA
ACAAAGCAGGGATGCGGGAC

Downstream 100 bases:

>100_bases
ACCGGCGTCGGACCGTTACCGCCCCATGCCTCGCATGCCGTCACGTGAATAAGGAATGATCAAGCTTTCTCTGGCCGGCT
CTGGCCGACGGAAAAGGGAA

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MAVLVTGGAGYIGSHMVWALLDAGEDVVVLDRLSTGFRWAVAPAARFYLGDVADPDVLKKIFIENDIEAIIHFAGSAVVP
VSVADPLSYYDNNSGKTRALLSASVEAGIRNFVFSSTAAVYGQQKTDLPVKETASLNPENPYGQSKLMTEFMLRDAASAY
DFNYVALRYFNVAGADPDHRAGQSTSGATHLIKVACEAALGRRDSVSVYGIDYPTHDGTGVRDYIHVTDLVDAHLKALQH
LRRGKGSLVANCGYGSGYSVLDVLNMVTRLHGHSFKIHMAPRRAGDSASVVADASLARQVLDWKPRHDSLETIVQSSLDW
ELFLSNRNVDDLHSIHRALAAASF

Sequences:

>Translated_344_residues
MAVLVTGGAGYIGSHMVWALLDAGEDVVVLDRLSTGFRWAVAPAARFYLGDVADPDVLKKIFIENDIEAIIHFAGSAVVP
VSVADPLSYYDNNSGKTRALLSASVEAGIRNFVFSSTAAVYGQQKTDLPVKETASLNPENPYGQSKLMTEFMLRDAASAY
DFNYVALRYFNVAGADPDHRAGQSTSGATHLIKVACEAALGRRDSVSVYGIDYPTHDGTGVRDYIHVTDLVDAHLKALQH
LRRGKGSLVANCGYGSGYSVLDVLNMVTRLHGHSFKIHMAPRRAGDSASVVADASLARQVLDWKPRHDSLETIVQSSLDW
ELFLSNRNVDDLHSIHRALAAASF
>Mature_343_residues
AVLVTGGAGYIGSHMVWALLDAGEDVVVLDRLSTGFRWAVAPAARFYLGDVADPDVLKKIFIENDIEAIIHFAGSAVVPV
SVADPLSYYDNNSGKTRALLSASVEAGIRNFVFSSTAAVYGQQKTDLPVKETASLNPENPYGQSKLMTEFMLRDAASAYD
FNYVALRYFNVAGADPDHRAGQSTSGATHLIKVACEAALGRRDSVSVYGIDYPTHDGTGVRDYIHVTDLVDAHLKALQHL
RRGKGSLVANCGYGSGYSVLDVLNMVTRLHGHSFKIHMAPRRAGDSASVVADASLARQVLDWKPRHDSLETIVQSSLDWE
LFLSNRNVDDLHSIHRALAAASF

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=317, Percent_Identity=40.3785488958991, Blast_Score=212, Evalue=4e-55,
Organism=Homo sapiens, GI56118217, Length=317, Percent_Identity=40.3785488958991, Blast_Score=212, Evalue=4e-55,
Organism=Homo sapiens, GI189083684, Length=317, Percent_Identity=40.3785488958991, Blast_Score=212, Evalue=4e-55,
Organism=Homo sapiens, GI7657641, Length=276, Percent_Identity=27.536231884058, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI42516563, Length=308, Percent_Identity=25.3246753246753, Blast_Score=79, Evalue=5e-15,
Organism=Escherichia coli, GI1786974, Length=330, Percent_Identity=42.4242424242424, Blast_Score=248, Evalue=3e-67,
Organism=Escherichia coli, GI1788353, Length=369, Percent_Identity=26.0162601626016, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI48994969, Length=356, Percent_Identity=27.5280898876405, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790049, Length=274, Percent_Identity=29.5620437956204, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71982035, Length=340, Percent_Identity=36.4705882352941, Blast_Score=201, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI71982038, Length=342, Percent_Identity=36.2573099415205, Blast_Score=200, Evalue=7e-52,
Organism=Caenorhabditis elegans, GI17568069, Length=247, Percent_Identity=30.3643724696356, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17539532, Length=317, Percent_Identity=25.2365930599369, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=319, Percent_Identity=37.9310344827586, Blast_Score=191, Evalue=1e-49,
Organism=Drosophila melanogaster, GI19923002, Length=337, Percent_Identity=40.3560830860534, Blast_Score=226, Evalue=1e-59,
Organism=Drosophila melanogaster, GI21356223, Length=337, Percent_Identity=27.0029673590504, Blast_Score=85, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37252; Mature: 37121

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLVTGGAGYIGSHMVWALLDAGEDVVVLDRLSTGFRWAVAPAARFYLGDVADPDVLKK
CEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECHHHHHHCCCCCCHHHHHH
IFIENDIEAIIHFAGSAVVPVSVADPLSYYDNNSGKTRALLSASVEAGIRNFVFSSTAAV
HHHHCHHHHHHHHCCCEEEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
YGQQKTDLPVKETASLNPENPYGQSKLMTEFMLRDAASAYDFNYVALRYFNVAGADPDHR
HCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCC
AGQSTSGATHLIKVACEAALGRRDSVSVYGIDYPTHDGTGVRDYIHVTDLVDAHLKALQH
CCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LRRGKGSLVANCGYGSGYSVLDVLNMVTRLHGHSFKIHMAPRRAGDSASVVADASLARQV
HHCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHH
LDWKPRHDSLETIVQSSLDWELFLSNRNVDDLHSIHRALAAASF
HCCCCCCHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AVLVTGGAGYIGSHMVWALLDAGEDVVVLDRLSTGFRWAVAPAARFYLGDVADPDVLKK
EEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECHHHHHHCCCCCCHHHHHH
IFIENDIEAIIHFAGSAVVPVSVADPLSYYDNNSGKTRALLSASVEAGIRNFVFSSTAAV
HHHHCHHHHHHHHCCCEEEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
YGQQKTDLPVKETASLNPENPYGQSKLMTEFMLRDAASAYDFNYVALRYFNVAGADPDHR
HCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCC
AGQSTSGATHLIKVACEAALGRRDSVSVYGIDYPTHDGTGVRDYIHVTDLVDAHLKALQH
CCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LRRGKGSLVANCGYGSGYSVLDVLNMVTRLHGHSFKIHMAPRRAGDSASVVADASLARQV
HHCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHH
LDWKPRHDSLETIVQSSLDWELFLSNRNVDDLHSIHRALAAASF
HCCCCCCHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8026752 [H]