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The map label for this gene is atoS [H]

Identifier: 209547696

GI number: 209547696

Start: 82575

End: 84107

Strand: Direct

Name: atoS [H]

Synonym: Rleg2_0084

Alternate gene names: 209547696

Gene position: 82575-84107 (Clockwise)

Preceding gene: 209547695

Following gene: 209547697

Centisome position: 1.82

GC content: 64.32

Gene sequence:

>1533_bases
ATGCCGGTACAAGATCAGGGCGACAATCCTTCGGCGGATATTCCCGCAGCCGGCGAGACCGCAAGGGCGCCGTGCCCGTC
TGCCGGCATGTTTGGCGGCATGTTCGGCGGATTGTCGGGCAAGCTGCTCTGGCTGACCGTCTTTTTTATCATGCTCGCCG
AAATCCTGATCTTCTTCCCCTCGGTCGCCAGCATGCGCATCCGCTGGCTGGAGGACAGGCTGAACACGGCCGCTGCCGCC
GCAATCGTCATCGATGGGCTGCAGCCGGTCGAGCTGCCGCGCGCGCTGCAGAAGGAGACGCTGGAGGCGACCGGCACCAA
GGCGATCGTGCTGCGCAAGGACGGCACTTCGCGGCTCTTGGCGACGACCGATATGCCGACCTCGGTCGATGAAGCCTATG
ATCTCACCGACGTGCCGCCGGCAACGGCGATGCGCGATGCGCTCGACACCTTGATCTTCGGCGGCAGCCGGATGATCCGC
GTCTACGGCCCGGTTGGCGACACCAATACCGGCGTCGAGGTGGTGATGAAGGACAGGCAGCTGCGCACCGCGATGTTTGC
CTATTCCCGCAACGTTCTCCTGCTGTCGGTGCTGATTTCGCTCTTTACCGCGACGCTGATCTTCTTTGCGATCAACCGCA
TCCTGATCGGCCCGATCCGCCGGCTGACCGGCAGCATGCAGCAATTCTCCTCCGATCCGGAAAACCCCGCCCATATTTAT
ATCGGCGACGGCGGCCGCGACGAATTGGCGGTTGCCGGCCGCAACCTCACCTCGATGCAGATGGAGCTGCAGAAGACGCT
GAAGCAGCAGAAGAACCTCGCCGCTCTCGGCCTCGCCGTTTCCAAGATCAATCACGACATGCGCAATATCCTGGCCTCGG
CGCAGCTGATGTCGGACCGGCTGGTCGATGTCGACGATCCGATGGTCAAAAGCTTCGCCCCGAAGCTGTTGCGCACCATC
GACCGCGCCGTCGGCTATACCACCGAGGTTCTGTCCTACGGCAAGGCCAGCGAATCCGCCCCGCGCCGCCGCCATATCCT
GCTTTTGGAACTCACCCAGGACGTCAAGGACATGCTGGCGATCGATCCGCAGAGCGGCATCGAATTCACCGAGCAGATCG
GCGCCGATCTGAAGGTCGATGCCGATGGTGAGCAACTGTTCCGGGTCATCCACAATCTCTGCCGCAACGCGCTGCAGGCG
CTGACGGCGCCGGGCGAGGGTGCCCCGGGCGCCGTCAGGCGCATCACCGTCGCCGCCCAGCGCGTCGGCAGTGTCGTCAG
CATCACCGTGGATGATACCGGCCCCGGTATGCCGCTGAAGGCGCGCCAGAACCTGTTTGCCGCCTTTCGCGGCTCCGCCC
GCTCCGGCGGCACCGGCCTCGGCCTGACGATCGCCCGCGAGCTGGTGCTCGCCCATGGCGGCACGATCGCGCTGGTGGAA
AAACCGACTGTGGGAACCCAGTTCCGCATCGAGATCCCCGATCGCCCGGTTTCGCTGGAGGATTACCGTAGCCGGACGCA
CAGCGAAAAGTGA

Upstream 100 bases:

>100_bases
TGGCGACATGACGCTGCTCGCAAAGATTTGAAAGCGGAGGCTTTTGGTCTAATATAGAACTCGAGGGCGGCTGAAGTGCT
GCCGATCGGGCGAGACGAAA

Downstream 100 bases:

>100_bases
CGGGCTTCCGAAAGCCGCGGCCGCAAATTATGAAACGCGCGATTTTTTCCGAAATGCTCTTGCATTGTCCCGAAGGACGC
TTTAGAGGATCGCCCACGCA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 509

Protein sequence:

>510_residues
MPVQDQGDNPSADIPAAGETARAPCPSAGMFGGMFGGLSGKLLWLTVFFIMLAEILIFFPSVASMRIRWLEDRLNTAAAA
AIVIDGLQPVELPRALQKETLEATGTKAIVLRKDGTSRLLATTDMPTSVDEAYDLTDVPPATAMRDALDTLIFGGSRMIR
VYGPVGDTNTGVEVVMKDRQLRTAMFAYSRNVLLLSVLISLFTATLIFFAINRILIGPIRRLTGSMQQFSSDPENPAHIY
IGDGGRDELAVAGRNLTSMQMELQKTLKQQKNLAALGLAVSKINHDMRNILASAQLMSDRLVDVDDPMVKSFAPKLLRTI
DRAVGYTTEVLSYGKASESAPRRRHILLLELTQDVKDMLAIDPQSGIEFTEQIGADLKVDADGEQLFRVIHNLCRNALQA
LTAPGEGAPGAVRRITVAAQRVGSVVSITVDDTGPGMPLKARQNLFAAFRGSARSGGTGLGLTIARELVLAHGGTIALVE
KPTVGTQFRIEIPDRPVSLEDYRSRTHSEK

Sequences:

>Translated_510_residues
MPVQDQGDNPSADIPAAGETARAPCPSAGMFGGMFGGLSGKLLWLTVFFIMLAEILIFFPSVASMRIRWLEDRLNTAAAA
AIVIDGLQPVELPRALQKETLEATGTKAIVLRKDGTSRLLATTDMPTSVDEAYDLTDVPPATAMRDALDTLIFGGSRMIR
VYGPVGDTNTGVEVVMKDRQLRTAMFAYSRNVLLLSVLISLFTATLIFFAINRILIGPIRRLTGSMQQFSSDPENPAHIY
IGDGGRDELAVAGRNLTSMQMELQKTLKQQKNLAALGLAVSKINHDMRNILASAQLMSDRLVDVDDPMVKSFAPKLLRTI
DRAVGYTTEVLSYGKASESAPRRRHILLLELTQDVKDMLAIDPQSGIEFTEQIGADLKVDADGEQLFRVIHNLCRNALQA
LTAPGEGAPGAVRRITVAAQRVGSVVSITVDDTGPGMPLKARQNLFAAFRGSARSGGTGLGLTIARELVLAHGGTIALVE
KPTVGTQFRIEIPDRPVSLEDYRSRTHSEK
>Mature_509_residues
PVQDQGDNPSADIPAAGETARAPCPSAGMFGGMFGGLSGKLLWLTVFFIMLAEILIFFPSVASMRIRWLEDRLNTAAAAA
IVIDGLQPVELPRALQKETLEATGTKAIVLRKDGTSRLLATTDMPTSVDEAYDLTDVPPATAMRDALDTLIFGGSRMIRV
YGPVGDTNTGVEVVMKDRQLRTAMFAYSRNVLLLSVLISLFTATLIFFAINRILIGPIRRLTGSMQQFSSDPENPAHIYI
GDGGRDELAVAGRNLTSMQMELQKTLKQQKNLAALGLAVSKINHDMRNILASAQLMSDRLVDVDDPMVKSFAPKLLRTID
RAVGYTTEVLSYGKASESAPRRRHILLLELTQDVKDMLAIDPQSGIEFTEQIGADLKVDADGEQLFRVIHNLCRNALQAL
TAPGEGAPGAVRRITVAAQRVGSVVSITVDDTGPGMPLKARQNLFAAFRGSARSGGTGLGLTIARELVLAHGGTIALVEK
PTVGTQFRIEIPDRPVSLEDYRSRTHSEK

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=244, Percent_Identity=26.6393442622951, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790300, Length=249, Percent_Identity=29.718875502008, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786912, Length=216, Percent_Identity=29.6296296296296, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790436, Length=245, Percent_Identity=26.9387755102041, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55166; Mature: 55035

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVQDQGDNPSADIPAAGETARAPCPSAGMFGGMFGGLSGKLLWLTVFFIMLAEILIFFP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
SVASMRIRWLEDRLNTAAAAAIVIDGLQPVELPRALQKETLEATGTKAIVLRKDGTSRLL
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCEEE
ATTDMPTSVDEAYDLTDVPPATAMRDALDTLIFGGSRMIRVYGPVGDTNTGVEVVMKDRQ
EECCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEHHHH
LRTAMFAYSRNVLLLSVLISLFTATLIFFAINRILIGPIRRLTGSMQQFSSDPENPAHIY
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
IGDGGRDELAVAGRNLTSMQMELQKTLKQQKNLAALGLAVSKINHDMRNILASAQLMSDR
ECCCCCCCCEECCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LVDVDDPMVKSFAPKLLRTIDRAVGYTTEVLSYGKASESAPRRRHILLLELTQDVKDMLA
CCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCHHEEEEEEHHHHHHHHHH
IDPQSGIEFTEQIGADLKVDADGEQLFRVIHNLCRNALQALTAPGEGAPGAVRRITVAAQ
CCCCCCCHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
RVGSVVSITVDDTGPGMPLKARQNLFAAFRGSARSGGTGLGLTIARELVLAHGGTIALVE
HHCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEE
KPTVGTQFRIEIPDRPVSLEDYRSRTHSEK
CCCCCCEEEEECCCCCCCHHHHHHHCCCCC
>Mature Secondary Structure 
PVQDQGDNPSADIPAAGETARAPCPSAGMFGGMFGGLSGKLLWLTVFFIMLAEILIFFP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
SVASMRIRWLEDRLNTAAAAAIVIDGLQPVELPRALQKETLEATGTKAIVLRKDGTSRLL
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCEEE
ATTDMPTSVDEAYDLTDVPPATAMRDALDTLIFGGSRMIRVYGPVGDTNTGVEVVMKDRQ
EECCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEHHHH
LRTAMFAYSRNVLLLSVLISLFTATLIFFAINRILIGPIRRLTGSMQQFSSDPENPAHIY
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
IGDGGRDELAVAGRNLTSMQMELQKTLKQQKNLAALGLAVSKINHDMRNILASAQLMSDR
ECCCCCCCCEECCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LVDVDDPMVKSFAPKLLRTIDRAVGYTTEVLSYGKASESAPRRRHILLLELTQDVKDMLA
CCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCHHEEEEEEHHHHHHHHHH
IDPQSGIEFTEQIGADLKVDADGEQLFRVIHNLCRNALQALTAPGEGAPGAVRRITVAAQ
CCCCCCCHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
RVGSVVSITVDDTGPGMPLKARQNLFAAFRGSARSGGTGLGLTIARELVLAHGGTIALVE
HHCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEE
KPTVGTQFRIEIPDRPVSLEDYRSRTHSEK
CCCCCCEEEEECCCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]