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The map label for this gene is mcpA [H]

Identifier: 209547695

GI number: 209547695

Start: 80232

End: 82229

Strand: Direct

Name: mcpA [H]

Synonym: Rleg2_0083

Alternate gene names: 209547695

Gene position: 80232-82229 (Clockwise)

Preceding gene: 209547686

Following gene: 209547696

Centisome position: 1.77

GC content: 64.96

Gene sequence:

>1998_bases
TTGAAGATCCGCGGCAAAATTAATCTGCTGGTATGCGTGATGGGCGCGGTGGCGCTTTTGATCGGCGCAACGGCGCTCTC
GGCCATGCACGAATACAATCGCAACCTGACGGCTTACGAGCAGGCTGCCGCCCGCGCCTATGCCGGCGAACGTCTCAACC
GCTTCGTCACGGCCGTGGTCATGGAAGCGCGCGGCATCTATGCGGCCAAGACGATCAAGGACACCCCGAACTTCGCCAAG
GGCCTGCTGGCCGGCCTCGACGAGATCGACAAGGTCATCGCGGGCTGGGCGCCGCTGGTTCCGGAAGACGAGAAGGGCGA
TTTCGCCAAGCTCGTCGCCCGCGCTGCGGAATTCCGCACCTTCCGTATGGAGACTGCCCGTCTCGGCACCGAAGTCGGCC
CCGAGGCCGCCAGCGCCCAGGGCAACAATGACGCCAACCGCGCCAACCGCAAGGCGTTCCAGGCCGAAATCGACGCGGTC
GTCGCCACCGACAAGGCAGCGCTCGAAACCGTCAACACCGAGATCGAAAGCTTCCGGACCTGGGTACTGATGCTCGTCCT
CAGCATCACCGGCATCGGCATCGCGGTCGGCATCGGCATGGGCTTCTATATCGGCACCAGCCATCTGAGCCGCCCGATCA
AGCGCGTCACCCGGGCGATCAACGAGGTCGCCAGCGGCAATTTCGAAGCCGAGGTCCCCTTTGCCGGGCGCCAGGATGAA
ATCGGCGAGATGGCCGCAGCCGTTGCGGTCTTCAAGGCCAACGGCCTTGCCGTCCAGCGCCTGAATGCCCAGGAGACGGC
GATGCGCGCCAAGAGCGACGACCTGCAGTCGAGCATGTCCGTCGTCGTGGCTGCGGCTGCGGCCGGCGACTTTGGCCATC
GCATCAGCAAGGACTACGAGGACGAGAACCTCAACCGCTTCGCCGGCAACATCAACACGCTGTTGTCGAGCGTCGATGCC
GGCATCGGCGAGACCCGCCGCGTCATTGCAAGCCTTGCCGATGGCGACCTCACCCAGACGATGAACGGCAGTTTCCAGGG
CGCCTTCGCCGAGCTGCAGCAGAACGTCAACAACACCTTCGTCACCCTGCAGGCGACCATGCGCGAAGTGCGCCAGACGA
CGGAAGCAATGAACGGCAACACCGCCGAACTGCGCAATGCCAGCGACGACCTGTCGAAGCGCACCGAGCAGCAGGCCGCC
GCCCTCGAACAGACTTCGGCGGCACTCGATCAGATCACCGCCGTCGTTCAGAATTCCACCGAGCGGGCGCATGAAGCCAC
CATCATGGTGTCGGAAGCCAAGGACAAGTCAGGCGCATCAGGCGTCGTCGTCGGCAATGCCGTCGAGGCCATGGGCCGCA
TCGAGCAGGCATCGCGCGAAATCAGCCAGATCATCAACGTCATCGATGAGATCGCCTTCCAGACCAACCTGCTGGCGCTG
AACGCCGGCGTCGAGGCGGCACGCGCCGGCGAGGCCGGCAAGGGCTTTGCGGTTGTGGCACAGGAAGTGCGCGAGCTCGC
CCAGCGTTCGGCAAAGGCTGCCAAGGACATCAAGGCGCTGATCACCAAATCGGGCAACGAGGTGCAGGTCGGCGTCAAGC
TCGTCCAGGCGACCGGGGAGGCGCTGGCGGAAATCGGCACCCGCGTCATCGCCATCAACGATCATATCCATTCGATCGCC
ACGGCTGCCACCGAACAGTCGACCGGCCTCAAGGAAGTCAATACCGCCGTCAACCAGATGGATCAGGTGACCCAGCAGAA
TGCCGCGATGGTGGAAGAGACCTCCGCCGCCACGCACAGGCTTTCGGCCGAAGCCGGCGGGCTGGTCCGCCTCATCTCCC
GCTTCAAGCTGTCGGATGATGCGCCGGCACCGGTGGCGCTTGTGCGCAACGAGCCGCAAAGACCGGTCGCCTCGCCCGCC
CGCCGGGCGATCGCCAAGGTCGCCCGCGCCTTCGGCGGCAACGCGGCCGCTGCGGAACAGAGCTGGGAAGAGTTCTGA

Upstream 100 bases:

>100_bases
CGTAAATATTGGAAATCTAACTTTAATAAATTTCGCCGATATTCCGATCATCGGCTGGAATTTGCTTTCCAGGCAGTGGC
GTAGCTCAGGAGACAGTGCA

Downstream 100 bases:

>100_bases
TCTGTTATCGATCATGCGCCATTTTTAACGCCGCCTCCGGGCGGCGTTAGTCTTTTCTGCCCGGTCCGCGCTGGGCAAAG
ACCCCGCCCCAAACCCCTCC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 665; Mature: 665

Protein sequence:

>665_residues
MKIRGKINLLVCVMGAVALLIGATALSAMHEYNRNLTAYEQAAARAYAGERLNRFVTAVVMEARGIYAAKTIKDTPNFAK
GLLAGLDEIDKVIAGWAPLVPEDEKGDFAKLVARAAEFRTFRMETARLGTEVGPEAASAQGNNDANRANRKAFQAEIDAV
VATDKAALETVNTEIESFRTWVLMLVLSITGIGIAVGIGMGFYIGTSHLSRPIKRVTRAINEVASGNFEAEVPFAGRQDE
IGEMAAAVAVFKANGLAVQRLNAQETAMRAKSDDLQSSMSVVVAAAAAGDFGHRISKDYEDENLNRFAGNINTLLSSVDA
GIGETRRVIASLADGDLTQTMNGSFQGAFAELQQNVNNTFVTLQATMREVRQTTEAMNGNTAELRNASDDLSKRTEQQAA
ALEQTSAALDQITAVVQNSTERAHEATIMVSEAKDKSGASGVVVGNAVEAMGRIEQASREISQIINVIDEIAFQTNLLAL
NAGVEAARAGEAGKGFAVVAQEVRELAQRSAKAAKDIKALITKSGNEVQVGVKLVQATGEALAEIGTRVIAINDHIHSIA
TAATEQSTGLKEVNTAVNQMDQVTQQNAAMVEETSAATHRLSAEAGGLVRLISRFKLSDDAPAPVALVRNEPQRPVASPA
RRAIAKVARAFGGNAAAAEQSWEEF

Sequences:

>Translated_665_residues
MKIRGKINLLVCVMGAVALLIGATALSAMHEYNRNLTAYEQAAARAYAGERLNRFVTAVVMEARGIYAAKTIKDTPNFAK
GLLAGLDEIDKVIAGWAPLVPEDEKGDFAKLVARAAEFRTFRMETARLGTEVGPEAASAQGNNDANRANRKAFQAEIDAV
VATDKAALETVNTEIESFRTWVLMLVLSITGIGIAVGIGMGFYIGTSHLSRPIKRVTRAINEVASGNFEAEVPFAGRQDE
IGEMAAAVAVFKANGLAVQRLNAQETAMRAKSDDLQSSMSVVVAAAAAGDFGHRISKDYEDENLNRFAGNINTLLSSVDA
GIGETRRVIASLADGDLTQTMNGSFQGAFAELQQNVNNTFVTLQATMREVRQTTEAMNGNTAELRNASDDLSKRTEQQAA
ALEQTSAALDQITAVVQNSTERAHEATIMVSEAKDKSGASGVVVGNAVEAMGRIEQASREISQIINVIDEIAFQTNLLAL
NAGVEAARAGEAGKGFAVVAQEVRELAQRSAKAAKDIKALITKSGNEVQVGVKLVQATGEALAEIGTRVIAINDHIHSIA
TAATEQSTGLKEVNTAVNQMDQVTQQNAAMVEETSAATHRLSAEAGGLVRLISRFKLSDDAPAPVALVRNEPQRPVASPA
RRAIAKVARAFGGNAAAAEQSWEEF
>Mature_665_residues
MKIRGKINLLVCVMGAVALLIGATALSAMHEYNRNLTAYEQAAARAYAGERLNRFVTAVVMEARGIYAAKTIKDTPNFAK
GLLAGLDEIDKVIAGWAPLVPEDEKGDFAKLVARAAEFRTFRMETARLGTEVGPEAASAQGNNDANRANRKAFQAEIDAV
VATDKAALETVNTEIESFRTWVLMLVLSITGIGIAVGIGMGFYIGTSHLSRPIKRVTRAINEVASGNFEAEVPFAGRQDE
IGEMAAAVAVFKANGLAVQRLNAQETAMRAKSDDLQSSMSVVVAAAAAGDFGHRISKDYEDENLNRFAGNINTLLSSVDA
GIGETRRVIASLADGDLTQTMNGSFQGAFAELQQNVNNTFVTLQATMREVRQTTEAMNGNTAELRNASDDLSKRTEQQAA
ALEQTSAALDQITAVVQNSTERAHEATIMVSEAKDKSGASGVVVGNAVEAMGRIEQASREISQIINVIDEIAFQTNLLAL
NAGVEAARAGEAGKGFAVVAQEVRELAQRSAKAAKDIKALITKSGNEVQVGVKLVQATGEALAEIGTRVIAINDHIHSIA
TAATEQSTGLKEVNTAVNQMDQVTQQNAAMVEETSAATHRLSAEAGGLVRLISRFKLSDDAPAPVALVRNEPQRPVASPA
RRAIAKVARAFGGNAAAAEQSWEEF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=337, Percent_Identity=42.433234421365, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1787690, Length=289, Percent_Identity=43.2525951557093, Blast_Score=209, Evalue=6e-55,
Organism=Escherichia coli, GI1788194, Length=257, Percent_Identity=47.8599221789883, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI2367378, Length=338, Percent_Identity=41.7159763313609, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1789453, Length=235, Percent_Identity=38.7234042553192, Blast_Score=145, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 70537; Mature: 70537

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRGKINLLVCVMGAVALLIGATALSAMHEYNRNLTAYEQAAARAYAGERLNRFVTAVV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MEARGIYAAKTIKDTPNFAKGLLAGLDEIDKVIAGWAPLVPEDEKGDFAKLVARAAEFRT
HHHCCCEEEHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
FRMETARLGTEVGPEAASAQGNNDANRANRKAFQAEIDAVVATDKAALETVNTEIESFRT
HHHHHHHHCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
WVLMLVLSITGIGIAVGIGMGFYIGTSHLSRPIKRVTRAINEVASGNFEAEVPFAGRQDE
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHH
IGEMAAAVAVFKANGLAVQRLNAQETAMRAKSDDLQSSMSVVVAAAAAGDFGHRISKDYE
HHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCC
DENLNRFAGNINTLLSSVDAGIGETRRVIASLADGDLTQTMNGSFQGAFAELQQNVNNTF
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHCCCCEE
VTLQATMREVRQTTEAMNGNTAELRNASDDLSKRTEQQAAALEQTSAALDQITAVVQNST
EEHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ERAHEATIMVSEAKDKSGASGVVVGNAVEAMGRIEQASREISQIINVIDEIAFQTNLLAL
HHHHHHEEEEECCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
NAGVEAARAGEAGKGFAVVAQEVRELAQRSAKAAKDIKALITKSGNEVQVGVKLVQATGE
ECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHH
ALAEIGTRVIAINDHIHSIATAATEQSTGLKEVNTAVNQMDQVTQQNAAMVEETSAATHR
HHHHHCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSAEAGGLVRLISRFKLSDDAPAPVALVRNEPQRPVASPARRAIAKVARAFGGNAAAAEQ
HHHCCCHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHH
SWEEF
HHHCC
>Mature Secondary Structure
MKIRGKINLLVCVMGAVALLIGATALSAMHEYNRNLTAYEQAAARAYAGERLNRFVTAVV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MEARGIYAAKTIKDTPNFAKGLLAGLDEIDKVIAGWAPLVPEDEKGDFAKLVARAAEFRT
HHHCCCEEEHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
FRMETARLGTEVGPEAASAQGNNDANRANRKAFQAEIDAVVATDKAALETVNTEIESFRT
HHHHHHHHCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
WVLMLVLSITGIGIAVGIGMGFYIGTSHLSRPIKRVTRAINEVASGNFEAEVPFAGRQDE
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHH
IGEMAAAVAVFKANGLAVQRLNAQETAMRAKSDDLQSSMSVVVAAAAAGDFGHRISKDYE
HHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCC
DENLNRFAGNINTLLSSVDAGIGETRRVIASLADGDLTQTMNGSFQGAFAELQQNVNNTF
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHCCCCEE
VTLQATMREVRQTTEAMNGNTAELRNASDDLSKRTEQQAAALEQTSAALDQITAVVQNST
EEHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ERAHEATIMVSEAKDKSGASGVVVGNAVEAMGRIEQASREISQIINVIDEIAFQTNLLAL
HHHHHHEEEEECCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
NAGVEAARAGEAGKGFAVVAQEVRELAQRSAKAAKDIKALITKSGNEVQVGVKLVQATGE
ECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHH
ALAEIGTRVIAINDHIHSIATAATEQSTGLKEVNTAVNQMDQVTQQNAAMVEETSAATHR
HHHHHCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSAEAGGLVRLISRFKLSDDAPAPVALVRNEPQRPVASPARRAIAKVARAFGGNAAAAEQ
HHHCCCHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHH
SWEEF
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]