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The map label for this gene is pgmB [H]

Identifier: 209400484

GI number: 209400484

Start: 1854977

End: 1855636

Strand: Direct

Name: pgmB [H]

Synonym: ECH74115_1962

Alternate gene names: 209400484

Gene position: 1854977-1855636 (Clockwise)

Preceding gene: 209397081

Following gene: 209398922

Centisome position: 33.29

GC content: 57.12

Gene sequence:

>660_bases
ATGAAACTGCAAGGGGTAATTTTCGATCTGGATGGTGTAATCACCGATACCGCGCATCTGCATTTCCAGGCGTGGCAGCA
GATTGCCGCTGAAATTGGCATCAGCATTGATGCGCAGTTTAACGAATCCCTAAAAGGGATCAGCCGCGATGAGTCTCTGC
GGCGCATTCTGCAACACGGGGGCAAAGAGGGCGACTTTAACCCGCAGGAGCGGACGCAACTGGCGTATCGCAAAAATCTG
CTTTACGTCCACTCACTGCGCGAGCTGACGGTTAATGCTGTGCTGCCCGGTATTCGCAATTTGCTGGCAGAGCTCCGCGC
ACAGCAGATCCCGGTAGGGCTGGCTTCTGTCTCCCTGAATGCGCCGACGATTTTAGCGGCGCTGGAGCTGCGCGAGTTTT
TCACCTTCTGCGCGGATGCTTCCCAACTTAAAAACTCGAAACCGGATCCGGAAATCTTTCTCGCTGCCTGTGCCGGGCTG
GGCGTGCCGCCGCAGGCATGTATCGGCATTGAAGATGCGCAGGCGGGCATTGACGCCATTAACGCCAGCGGTATGCGCTC
GGTGGGGATCGGCGCAGGCTTAACCGGGGCGCAATTATTGTTGCCCTCAACGGACTCCCTGACCTGGCCGCGGTTATCGG
CCTTCTGGCAAAACGTATAG

Upstream 100 bases:

>100_bases
TGAACGGGCAGCTTATATCCGTGGCTGAAGAATCTGTTTTCTGTTTGGGTGATTTTATTTTGCCCTTCAATGGGACCGCT
ACCACGCATCAGGAGGATGA

Downstream 100 bases:

>100_bases
CAAAGGAATCAACATGGCTCAGCTTTCGTTACAACATATTCAAAAAATCTACGATAACCAGGTGCATGTGGTGAAGGACT
TCAACCTGGAAATTGCCGAT

Product: beta-phosphoglucomutase

Products: NA

Alternate protein names: Beta-PGM [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MKLQGVIFDLDGVITDTAHLHFQAWQQIAAEIGISIDAQFNESLKGISRDESLRRILQHGGKEGDFNPQERTQLAYRKNL
LYVHSLRELTVNAVLPGIRNLLAELRAQQIPVGLASVSLNAPTILAALELREFFTFCADASQLKNSKPDPEIFLAACAGL
GVPPQACIGIEDAQAGIDAINASGMRSVGIGAGLTGAQLLLPSTDSLTWPRLSAFWQNV

Sequences:

>Translated_219_residues
MKLQGVIFDLDGVITDTAHLHFQAWQQIAAEIGISIDAQFNESLKGISRDESLRRILQHGGKEGDFNPQERTQLAYRKNL
LYVHSLRELTVNAVLPGIRNLLAELRAQQIPVGLASVSLNAPTILAALELREFFTFCADASQLKNSKPDPEIFLAACAGL
GVPPQACIGIEDAQAGIDAINASGMRSVGIGAGLTGAQLLLPSTDSLTWPRLSAFWQNV
>Mature_219_residues
MKLQGVIFDLDGVITDTAHLHFQAWQQIAAEIGISIDAQFNESLKGISRDESLRRILQHGGKEGDFNPQERTQLAYRKNL
LYVHSLRELTVNAVLPGIRNLLAELRAQQIPVGLASVSLNAPTILAALELREFFTFCADASQLKNSKPDPEIFLAACAGL
GVPPQACIGIEDAQAGIDAINASGMRSVGIGAGLTGAQLLLPSTDSLTWPRLSAFWQNV

Specific function: Reversible transformation of glucose 6-phosphate and beta-glucose 1-phosphate [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Homo sapiens, GI197382691, Length=199, Percent_Identity=28.643216080402, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1787576, Length=219, Percent_Identity=97.2602739726027, Blast_Score=433, Evalue=1e-123,
Organism=Escherichia coli, GI1789046, Length=191, Percent_Identity=30.8900523560209, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788021, Length=188, Percent_Identity=30.3191489361702, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789787, Length=212, Percent_Identity=25.4716981132075, Blast_Score=63, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17137324, Length=197, Percent_Identity=28.4263959390863, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI116008157, Length=200, Percent_Identity=27.5, Blast_Score=71, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010976
- InterPro:   IPR010972
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =5.4.2.6 [H]

Molecular weight: Translated: 23642; Mature: 23642

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLQGVIFDLDGVITDTAHLHFQAWQQIAAEIGISIDAQFNESLKGISRDESLRRILQHG
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHHHCC
GKEGDFNPQERTQLAYRKNLLYVHSLRELTVNAVLPGIRNLLAELRAQQIPVGLASVSLN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
APTILAALELREFFTFCADASQLKNSKPDPEIFLAACAGLGVPPQACIGIEDAQAGIDAI
CCHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHCCCCCHHHHCCCCHHHHCHHHH
NASGMRSVGIGAGLTGAQLLLPSTDSLTWPRLSAFWQNV
CCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MKLQGVIFDLDGVITDTAHLHFQAWQQIAAEIGISIDAQFNESLKGISRDESLRRILQHG
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHHHCC
GKEGDFNPQERTQLAYRKNLLYVHSLRELTVNAVLPGIRNLLAELRAQQIPVGLASVSLN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
APTILAALELREFFTFCADASQLKNSKPDPEIFLAACAGLGVPPQACIGIEDAQAGIDAI
CCHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHCCCCCHHHHCCCCHHHHCHHHH
NASGMRSVGIGAGLTGAQLLLPSTDSLTWPRLSAFWQNV
CCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]