Click here to switch to the map view.

The map label for this gene is garK [H]

Identifier: 209399632

GI number: 209399632

Start: 4112943

End: 4114088

Strand: Reverse

Name: garK [H]

Synonym: ECH74115_4436

Alternate gene names: 209399632

Gene position: 4114088-4112943 (Counterclockwise)

Preceding gene: 209399219

Following gene: 209396695

Centisome position: 73.83

GC content: 53.75

Gene sequence:

>1146_bases
ATGAAAATCGTAATCGCCCCAGACTCTTATAAAGAAAGTTTATCTGCCAGCGAGGTTGCGCAGGCGATAGAAAAAGGATT
TCGGGAAATTTTTCCTGATGCACAGTACGTTTCTGTTCCTGTTGCCGACGGTGGCGAAGGAACGGTGGAAGCGATGATTG
CAGCCACCCAGGGTTCCGAACGTCACGCCTGGGTTACAGGGCCGCTGGGCGAGAAAGTGAATGCCAGTTGGGGGATCTCC
GGCGATGGCAAAACCGCGTTTATTGAAATGGCGGCGGCCAGTGGGCTGGAGCTGGTACCTGCGGAAAAACGCGATCCACT
CGTGACCACTTCACGCGGCACAGGCGAGTTAATCCTGCAGGCGCTGGAGAGCGGCGCGACAAACATTATTATCGGCATTG
GCGGCAGCGCTACAAATGATGGCGGCGCAGGCATGGTACAGGCGCTGGGGGCGAAATTATGCGACGCCAACGGCAATGAA
ATTGGTTTTGGCGGCGGTAGTCTTAATACTCTGAATGATATTGATATTTCCGGCCTCGATCCGCGCTTAAAAGATTGCGT
CATTCGCGTCGCTTGTGATGTCACCAATCCGCTGGTGGGCGATAACGGCGCATCGCGCATCTTTGGCCCACAAAAGGGAG
CCAGTGAAGCGATGATTGTTGAGCTGGACAATAACCTCTCTCACTATGCCGAGGTCATTAAAAAAGCGCTGCATGTTGAT
GTGAAAGATGTCCCCGGCGCAGGAGCTGCGGGTGGTATGGGCGCGGCGCTAATGGCGTTTCTTGGTGCGGAACTGAAAAG
TGGTATTGAAATCGTCACTACGGCGCTGAATCTGGAGGAACATATTCACGATTGTACGCTGGTGATCACCGGTGAAGGGC
GTATTGACAGCCAGAGTATTCACGGCAAGGTACCGATTGGTGTCGCAAACGTGGCGAAGAAGTACCATAAACCGGTGATT
GGCATTGCGGGTAGCCTGACCGATGATGTTGGCGTTGTACATCAGCATGGCATTGATGCGGTCTTCAGCGTATTGACCAG
CATAGGTACGTTGGACGAAGCATTCCGCGGGGCTTATGACAATATCTGCCGTGCTTCACGTAATATCGCCGCGACACTGG
CGATTGGAATGCGCAACGCGGGGTGA

Upstream 100 bases:

>100_bases
TTAATGACGTCGTGCCCGGATGGCGTATTGCAATCCGGGCCTGGAATCCAGGCCGAATAAGAGAAACGCCCTCCGGCGTC
ATGTGGTAACAGGCATAGGT

Downstream 100 bases:

>100_bases
CAAGGGCGCGCAAACCCTCTATACTGCGCGCCGAAGCTGACCAGACAGTCGCCGCTTCGTCGTCGTCCTCTTCGGGGGAG
ACGGGCGGAGGGGAGGAAAG

Product: glycerate kinase I

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKIVIAPDSYKESLSASEVAQAIEKGFREIFPDAQYVSVPVADGGEGTVEAMIAATQGSERHAWVTGPLGEKVNASWGIS
GDGKTAFIEMAAASGLELVPAEKRDPLVTTSRGTGELILQALESGATNIIIGIGGSATNDGGAGMVQALGAKLCDANGNE
IGFGGGSLNTLNDIDISGLDPRLKDCVIRVACDVTNPLVGDNGASRIFGPQKGASEAMIVELDNNLSHYAEVIKKALHVD
VKDVPGAGAAGGMGAALMAFLGAELKSGIEIVTTALNLEEHIHDCTLVITGEGRIDSQSIHGKVPIGVANVAKKYHKPVI
GIAGSLTDDVGVVHQHGIDAVFSVLTSIGTLDEAFRGAYDNICRASRNIAATLAIGMRNAG

Sequences:

>Translated_381_residues
MKIVIAPDSYKESLSASEVAQAIEKGFREIFPDAQYVSVPVADGGEGTVEAMIAATQGSERHAWVTGPLGEKVNASWGIS
GDGKTAFIEMAAASGLELVPAEKRDPLVTTSRGTGELILQALESGATNIIIGIGGSATNDGGAGMVQALGAKLCDANGNE
IGFGGGSLNTLNDIDISGLDPRLKDCVIRVACDVTNPLVGDNGASRIFGPQKGASEAMIVELDNNLSHYAEVIKKALHVD
VKDVPGAGAAGGMGAALMAFLGAELKSGIEIVTTALNLEEHIHDCTLVITGEGRIDSQSIHGKVPIGVANVAKKYHKPVI
GIAGSLTDDVGVVHQHGIDAVFSVLTSIGTLDEAFRGAYDNICRASRNIAATLAIGMRNAG
>Mature_381_residues
MKIVIAPDSYKESLSASEVAQAIEKGFREIFPDAQYVSVPVADGGEGTVEAMIAATQGSERHAWVTGPLGEKVNASWGIS
GDGKTAFIEMAAASGLELVPAEKRDPLVTTSRGTGELILQALESGATNIIIGIGGSATNDGGAGMVQALGAKLCDANGNE
IGFGGGSLNTLNDIDISGLDPRLKDCVIRVACDVTNPLVGDNGASRIFGPQKGASEAMIVELDNNLSHYAEVIKKALHVD
VKDVPGAGAAGGMGAALMAFLGAELKSGIEIVTTALNLEEHIHDCTLVITGEGRIDSQSIHGKVPIGVANVAKKYHKPVI
GIAGSLTDDVGVVHQHGIDAVFSVLTSIGTLDEAFRGAYDNICRASRNIAATLAIGMRNAG

Specific function: Unknown

COG id: COG1929

COG function: function code G; Glycerate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycerate kinase type-1 family [H]

Homologues:

Organism=Escherichia coli, GI145693185, Length=381, Percent_Identity=99.737532808399, Blast_Score=764, Evalue=0.0,
Organism=Escherichia coli, GI1786724, Length=376, Percent_Identity=56.3829787234042, Blast_Score=392, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018193
- InterPro:   IPR004381 [H]

Pfam domain/function: PF02595 Gly_kinase [H]

EC number: =2.7.1.31 [H]

Molecular weight: Translated: 39121; Mature: 39121

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVIAPDSYKESLSASEVAQAIEKGFREIFPDAQYVSVPVADGGEGTVEAMIAATQGSE
CEEEECCCHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEEECCCCC
RHAWVTGPLGEKVNASWGISGDGKTAFIEMAAASGLELVPAEKRDPLVTTSRGTGELILQ
CCEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCEECCCCCCCCEEEECCCHHHHHHH
ALESGATNIIIGIGGSATNDGGAGMVQALGAKLCDANGNEIGFGGGSLNTLNDIDISGLD
HHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCC
PRLKDCVIRVACDVTNPLVGDNGASRIFGPQKGASEAMIVELDNNLSHYAEVIKKALHVD
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCC
VKDVPGAGAAGGMGAALMAFLGAELKSGIEIVTTALNLEEHIHDCTLVITGEGRIDSQSI
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCEEEEEEECCCCCCCCCC
HGKVPIGVANVAKKYHKPVIGIAGSLTDDVGVVHQHGIDAVFSVLTSIGTLDEAFRGAYD
CCCCCCCHHHHHHHHCCCEEEECCCCCCCHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHH
NICRASRNIAATLAIGMRNAG
HHHHHCCCEEEEEEEECCCCC
>Mature Secondary Structure
MKIVIAPDSYKESLSASEVAQAIEKGFREIFPDAQYVSVPVADGGEGTVEAMIAATQGSE
CEEEECCCHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEEECCCCC
RHAWVTGPLGEKVNASWGISGDGKTAFIEMAAASGLELVPAEKRDPLVTTSRGTGELILQ
CCEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCEECCCCCCCCEEEECCCHHHHHHH
ALESGATNIIIGIGGSATNDGGAGMVQALGAKLCDANGNEIGFGGGSLNTLNDIDISGLD
HHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCC
PRLKDCVIRVACDVTNPLVGDNGASRIFGPQKGASEAMIVELDNNLSHYAEVIKKALHVD
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCC
VKDVPGAGAAGGMGAALMAFLGAELKSGIEIVTTALNLEEHIHDCTLVITGEGRIDSQSI
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCEEEEEEECCCCCCCCCC
HGKVPIGVANVAKKYHKPVIGIAGSLTDDVGVVHQHGIDAVFSVLTSIGTLDEAFRGAYD
CCCCCCCHHHHHHHHCCCEEEECCCCCCCHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHH
NICRASRNIAATLAIGMRNAG
HHHHHCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1705543; 9278503 [H]