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The map label for this gene is gbpR [H]

Identifier: 209398611

GI number: 209398611

Start: 3005941

End: 3006849

Strand: Direct

Name: gbpR [H]

Synonym: ECH74115_3272

Alternate gene names: 209398611

Gene position: 3005941-3006849 (Clockwise)

Preceding gene: 209396851

Following gene: 209399235

Centisome position: 53.95

GC content: 49.94

Gene sequence:

>909_bases
ATGGCGAACTGGGCGCAAAAATTAAAACTACATCACCTTGAAATGCTGGTGGCGCTGGGTGAACAGGGCAATCTAACCCA
TGTCGCACGAATGATGAATATCACCCAACCTGCGCTTTCGAAATGGTTGTCACAACTCGAAGATGAGATTGGAATCACAC
TTTTTGAGCGGCACAGCAAAGGATTACGTCCGACTGAAGGCGGCAAATTGTTATTGCAACATGCCCAACGGTTAATCAAT
GACATGGAGCGATCGCAACATGAACTGGCCCGTTTTAAACAAGGTGGACTGGTCGGCAGTCTGAAAATTGGCTGTTCTCC
CGTCGCCACTGACTGCGTATCCCAGGCGATTTTGCATTTGCTTACGAAGATGCCAACTCTACACCTGAATATCGAAGAGA
AGGTGATGACCCCATTGCTGCAAGATCTATTGGCCGGTTCTGTCGATGTGGTCGTTGGGCGAATTGGCGGTCGCGCATTG
CAGCTGCCACTGAATTATCAGGTGCTGTACACCGAGCCAGTATGCTTTGTCGCCCGCCCTGAGCACCCACTGGCGAAATA
CGCCACCCTCAGCTGGAATGATCTTGCCAACTGGCGCTGGATCGTCTGGCCGACGGGTACCCCCATTCGCATTAGTATTG
ATAATGCGCTGGTAGACCACGGCGTAATGCTGCCAGAAAACACGATTGAGTCGGCGTCGATGAACGTCAGTACCAACCTG
TTACAAAGCAGCGATATGATCTCTATTTTGTCATTACGCCTGGCGCAACGTTATGCCAGCCAGGGACAACTGGTGATACT
CAACCTGCCAAAGATAGAACAGAAAGGTAGCGTCGGTGTGTTCTGGCGCAATAACGAAACGCCTTCTTATGCTTTAAGTC
AGTTTCTGCACTTTTTACAGCAGAATTAG

Upstream 100 bases:

>100_bases
AGATGTTTCTTTTGTTTTGTATATGTTGCGATATTGTGATTAAAGAGATGAGATGTACAATGGCATTTCGGGCAGAGAGA
TAACCTTGAGGTTATGGCAA

Downstream 100 bases:

>100_bases
TGTGCTGAACGGGGCGCTCGCCCGAGGTTACCTCCCTAAAATTCAACTATGCTGAGAATTCTTAATGTGATCGGTAGCTC
GTTTTACGAATTAATTGTAT

Product: transcriptional regulator, LysR family

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MANWAQKLKLHHLEMLVALGEQGNLTHVARMMNITQPALSKWLSQLEDEIGITLFERHSKGLRPTEGGKLLLQHAQRLIN
DMERSQHELARFKQGGLVGSLKIGCSPVATDCVSQAILHLLTKMPTLHLNIEEKVMTPLLQDLLAGSVDVVVGRIGGRAL
QLPLNYQVLYTEPVCFVARPEHPLAKYATLSWNDLANWRWIVWPTGTPIRISIDNALVDHGVMLPENTIESASMNVSTNL
LQSSDMISILSLRLAQRYASQGQLVILNLPKIEQKGSVGVFWRNNETPSYALSQFLHFLQQN

Sequences:

>Translated_302_residues
MANWAQKLKLHHLEMLVALGEQGNLTHVARMMNITQPALSKWLSQLEDEIGITLFERHSKGLRPTEGGKLLLQHAQRLIN
DMERSQHELARFKQGGLVGSLKIGCSPVATDCVSQAILHLLTKMPTLHLNIEEKVMTPLLQDLLAGSVDVVVGRIGGRAL
QLPLNYQVLYTEPVCFVARPEHPLAKYATLSWNDLANWRWIVWPTGTPIRISIDNALVDHGVMLPENTIESASMNVSTNL
LQSSDMISILSLRLAQRYASQGQLVILNLPKIEQKGSVGVFWRNNETPSYALSQFLHFLQQN
>Mature_301_residues
ANWAQKLKLHHLEMLVALGEQGNLTHVARMMNITQPALSKWLSQLEDEIGITLFERHSKGLRPTEGGKLLLQHAQRLIND
MERSQHELARFKQGGLVGSLKIGCSPVATDCVSQAILHLLTKMPTLHLNIEEKVMTPLLQDLLAGSVDVVVGRIGGRALQ
LPLNYQVLYTEPVCFVARPEHPLAKYATLSWNDLANWRWIVWPTGTPIRISIDNALVDHGVMLPENTIESASMNVSTNLL
QSSDMISILSLRLAQRYASQGQLVILNLPKIEQKGSVGVFWRNNETPSYALSQFLHFLQQN

Specific function: Does not seem to be required for sbpA expression [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081904, Length=302, Percent_Identity=28.1456953642384, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787601, Length=296, Percent_Identity=24.3243243243243, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI157672245, Length=291, Percent_Identity=24.0549828178694, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI145693105, Length=294, Percent_Identity=24.1496598639456, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1790399, Length=281, Percent_Identity=24.5551601423488, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789204, Length=268, Percent_Identity=27.6119402985075, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787879, Length=198, Percent_Identity=26.7676767676768, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789639, Length=150, Percent_Identity=27.3333333333333, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789506, Length=259, Percent_Identity=21.2355212355212, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1790262, Length=231, Percent_Identity=27.7056277056277, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788297, Length=212, Percent_Identity=25, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33801; Mature: 33670

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANWAQKLKLHHLEMLVALGEQGNLTHVARMMNITQPALSKWLSQLEDEIGITLFERHSK
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEECCCC
GLRPTEGGKLLLQHAQRLINDMERSQHELARFKQGGLVGSLKIGCSPVATDCVSQAILHL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHH
LTKMPTLHLNIEEKVMTPLLQDLLAGSVDVVVGRIGGRALQLPLNYQVLYTEPVCFVARP
HHHCCEEEECHHHHHHHHHHHHHHCCCHHEEEECCCCEEEEECCCEEEEEECCEEEEECC
EHPLAKYATLSWNDLANWRWIVWPTGTPIRISIDNALVDHGVMLPENTIESASMNVSTNL
CCCCHHEEECCCCCCCCEEEEEECCCCEEEEEECCHHHHCCCCCCCCCHHHCCCCHHHHH
LQSSDMISILSLRLAQRYASQGQLVILNLPKIEQKGSVGVFWRNNETPSYALSQFLHFLQ
HHCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHH
QN
CC
>Mature Secondary Structure 
ANWAQKLKLHHLEMLVALGEQGNLTHVARMMNITQPALSKWLSQLEDEIGITLFERHSK
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEECCCC
GLRPTEGGKLLLQHAQRLINDMERSQHELARFKQGGLVGSLKIGCSPVATDCVSQAILHL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHH
LTKMPTLHLNIEEKVMTPLLQDLLAGSVDVVVGRIGGRALQLPLNYQVLYTEPVCFVARP
HHHCCEEEECHHHHHHHHHHHHHHCCCHHEEEECCCCEEEEECCCEEEEEECCEEEEECC
EHPLAKYATLSWNDLANWRWIVWPTGTPIRISIDNALVDHGVMLPENTIESASMNVSTNL
CCCCHHEEECCCCCCCCEEEEEECCCCEEEEEECCHHHHCCCCCCCCCHHHCCCCHHHHH
LQSSDMISILSLRLAQRYASQGQLVILNLPKIEQKGSVGVFWRNNETPSYALSQFLHFLQ
HHCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHH
QN
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]